Progress in research on the roles of TGR5 receptor in liver diseases
Published 2021 View Full Article
- Home
- Publications
- Publication Search
- Publication Details
Title
Progress in research on the roles of TGR5 receptor in liver diseases
Authors
Keywords
-
Journal
SCANDINAVIAN JOURNAL OF GASTROENTEROLOGY
Volume -, Issue -, Pages 1-10
Publisher
Informa UK Limited
Online
2021-03-27
DOI
10.1080/00365521.2021.1903547
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- Dual Agonist of Farnesoid X Receptor and G Protein‐coupled Receptor TGR5 Inhibits Hepatitis B Virus Infection in Vitro and in Vivo
- (2021) Kiyoaki Ito et al. HEPATOLOGY
- TGR5 promotes cholangiocarcinoma by interacting with mortalin
- (2020) Ai-Di Li et al. EXPERIMENTAL CELL RESEARCH
- Hepatoprotective impact of the bile acid receptor TGR5
- (2020) Grégory Merlen et al. LIVER INTERNATIONAL
- Long-term abuse of a high-carbohydrate diet is as harmful as a high-fat diet for development and progression of liver injury in a mouse model of NAFLD/NASH
- (2020) Simona Pompili et al. NUTRITION
- Roseotoxin B alleviates cholestatic liver fibrosis through inhibiting PDGF-B/PDGFR-β pathway in hepatic stellate cells
- (2020) Xingqi Wang et al. Cell Death & Disease
- Deficiency of both farnesoid X receptor and Takeda G protein-coupled receptor 5 exacerbated liver fibrosis in mice
- (2019) Jessica M. Ferrell et al. HEPATOLOGY
- TGR5-dependent hepatoprotection through the regulation of biliary epithelium barrier function
- (2019) Grégory Merlen et al. GUT
- Augmenter of liver regeneration enhances cell proliferation through the microRNA‐26a/Akt/cyclin D1 pathway in hepatic cells
- (2019) Parul Gupta et al. HEPATOLOGY RESEARCH
- Smooth Muscle α-Actin Deficiency Leads to Decreased Liver Fibrosis via Impaired Cytoskeletal Signaling in Hepatic Stellate Cells
- (2019) Don C. Rockey et al. AMERICAN JOURNAL OF PATHOLOGY
- Quercetin improves nonalcoholic fatty liver by ameliorating inflammation, oxidative stress, and lipid metabolism in db / db mice
- (2019) Hao Yang et al. PHYTOTHERAPY RESEARCH
- TGR5 Activation Modulates an Inhibitory Effect on Liver Fibrosis Development Mediated by Anagliptin in Diabetic Rats
- (2019) Daisuke Kaya et al. Cells
- TGR5 agonist ameliorates insulin resistance in skeletal muscles and improves glucose homeostasis in diabetic mice
- (2019) Suling Huang et al. METABOLISM-CLINICAL AND EXPERIMENTAL
- The G Protein-Coupled Bile Acid Receptor TGR5 (Gpbar1) Modulates Endothelin-1 Signaling in Liver
- (2019) Caroline Klindt et al. Cells
- Modulation of endothelium-derived nitric oxide production and activity by taurine and taurine-conjugated bile acids
- (2019) Daniele M. Guizoni et al. NITRIC OXIDE-BIOLOGY AND CHEMISTRY
- Gentiopicroside activates the bile acid receptor Gpbar1 (TGR5) to repress NF-kappaB pathway and ameliorate diabetic nephropathy
- (2019) Haiming Xiao et al. PHARMACOLOGICAL RESEARCH
- Differential effects of FXR or TGR5 activation in cholangiocarcinoma progression
- (2018) O. Erice et al. BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE
- The tumor suppressive miR-26a regulation of FBXO11 inhibits proliferation, migration and invasion of hepatocellular carcinoma cells
- (2018) Yue Ma et al. BIOMEDICINE & PHARMACOTHERAPY
- Dual catenin loss in murine liver causes tight junctional deregulation and progressive intrahepatic cholestasis
- (2018) Tirthadipa Pradhan-Sundd et al. HEPATOLOGY
- Liver fibrosis
- (2018) M. Merve Aydin et al. Turkish Journal of Gastroenterology
- An update on the recent advances in antifibrotic therapy
- (2018) Frank Tacke et al. Expert Review of Gastroenterology & Hepatology
- Agonism for the bile acid receptor GPBAR1 reverses liver and vascular damage in a mouse model of steatohepatitis
- (2018) Adriana Carino et al. FASEB JOURNAL
- Role of TGR5 (GPBAR1) in Liver Disease
- (2018) Dieter Häussinger et al. SEMINARS IN LIVER DISEASE
- TGR5 contributes to hepatic cystogenesis in rodents with polycystic liver diseases through cyclic adenosine monophosphate/Gαs signaling
- (2017) Tatyana V. Masyuk et al. HEPATOLOGY
- Biology of portal hypertension
- (2017) Matthew McConnell et al. Hepatology International
- Bile acids and their receptors during liver regeneration: “Dangerous protectors”
- (2017) Grégory Merlen et al. MOLECULAR ASPECTS OF MEDICINE
- Mechanisms of hepatic stellate cell activation
- (2017) Takuma Tsuchida et al. Nature Reviews Gastroenterology & Hepatology
- Junctional Adhesion Molecules (JAMs): Cell Adhesion Receptors With Pleiotropic Functions in Cell Physiology and Development
- (2017) Klaus Ebnet PHYSIOLOGICAL REVIEWS
- Gpbar1 agonism promotes a Pgc-1α-dependent browning of white adipose tissue and energy expenditure and reverses diet-induced steatohepatitis in mice
- (2017) Adriana Carino et al. Scientific Reports
- Ischemic Preconditioning protects hepatocytes from ischemia-reperfusion injury via TGR5-mediated anti-apoptosis
- (2016) Lin Zhuang et al. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
- Persistent Nonalcoholic Fatty Liver Disease Increases Risk for Carotid Atherosclerosis
- (2016) Dong Hyun Sinn et al. GASTROENTEROLOGY
- G-protein-coupled bile acid receptor plays a key role in bile acid metabolism and fasting-induced hepatic steatosis in mice
- (2016) Ajay C. Donepudi et al. HEPATOLOGY
- The myeloid heat shock transcription factor 1/β-catenin axis regulates NLR family, pyrin domain-containing 3 inflammasome activation in mouse liver ischemia/reperfusion injury
- (2016) Shi Yue et al. HEPATOLOGY
- Vertical sleeve gastrectomy activates GPBAR-1/TGR5 to sustain weight loss, improve fatty liver, and remit insulin resistance in mice
- (2016) Lili Ding et al. HEPATOLOGY
- Global epidemiology of nonalcoholic fatty liver disease-Meta-analytic assessment of prevalence, incidence, and outcomes
- (2016) Zobair M. Younossi et al. HEPATOLOGY
- Hepatic sinusoids in liver injury, inflammation, and fibrosis: new pathophysiological insights
- (2016) Thomas Greuter et al. JOURNAL OF GASTROENTEROLOGY
- Non-alcoholic fatty liver disease and cardiovascular risk: Pathophysiological mechanisms and implications
- (2016) Sven M. Francque et al. JOURNAL OF HEPATOLOGY
- EASL–EASD–EASO Clinical Practice Guidelines for the management of non-alcoholic fatty liver disease
- (2016) JOURNAL OF HEPATOLOGY
- Sinusoidal communication in liver fibrosis and regeneration
- (2016) Giusi Marrone et al. JOURNAL OF HEPATOLOGY
- Nonalcoholic Fatty Liver Disease and Incident Cardiac Events
- (2016) Irfan Zeb et al. JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY
- Plasma membrane-bound G protein-coupled bile acid receptor attenuates liver ischemia/reperfusion injury via the inhibition of toll-like receptor 4 signaling in mice
- (2016) Haojun Yang et al. LIVER TRANSPLANTATION
- Chenodeoxycholic acid activates NLRP3 inflammasome and contributes to cholestatic liver fibrosis
- (2016) Zizhen Gong et al. Oncotarget
- Targeting the PDGF-B/PDGFR-β Interface with Destruxin A5 to Selectively Block PDGF-BB/PDGFR-ββ Signaling and Attenuate Liver Fibrosis
- (2016) Xingqi Wang et al. EBioMedicine
- Cystathionine γ-lyase, a H2S-generating enzyme, is a GPBAR1-regulated gene and contributes to vasodilation caused by secondary bile acids
- (2015) Barbara Renga et al. AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY
- Association Between Quantity of Liver Fat and Cardiovascular Risk in Patients With Nonalcoholic Fatty Liver Disease Independent of Nonalcoholic Steatohepatitis
- (2015) Ahilan Arulanandan et al. Clinical Gastroenterology and Hepatology
- TGR5 in the Cholangiociliopathies
- (2015) Tatyana V. Masyuk et al. DIGESTIVE DISEASES
- TGR5 is essential for bile acid-dependent cholangiocyte proliferation in vivo and in vitro
- (2015) Maria Reich et al. GUT
- Bile acids induce hepatic differentiation of mesenchymal stem cells
- (2015) Iris Sawitza et al. Scientific Reports
- Identification of miR-26a as a Target Gene of Bile Acid Receptor GPBAR-1/TGR5
- (2015) Xiaosong Chen et al. PLoS One
- Reversal of Endothelial Dysfunction by GPBAR1 Agonism in Portal Hypertension Involves a AKT/FOXOA1 Dependent Regulation of H2S Generation and Endothelin-1
- (2015) Barbara Renga et al. PLoS One
- Primary biliary tract malignancies: MRI spectrum and mimics with histopathological correlation
- (2014) Pardeep K. Mittal et al. ABDOMINAL IMAGING
- ATF6 Mediates a Pro-Inflammatory Synergy Between ER Stress and TLR Activation in the Pathogenesis of Liver Ischemia-Reperfusion Injury
- (2014) J. Rao et al. AMERICAN JOURNAL OF TRANSPLANTATION
- ATF3-Mediated NRF2/HO-1 Signaling Regulates TLR4 Innate Immune Responses in Mouse Liver Ischemia/Reperfusion Injury
- (2014) J. Rao et al. AMERICAN JOURNAL OF TRANSPLANTATION
- The Hepatobiliary Paracellular Pathway: A Paradigm Revisited
- (2014) James L. Boyer GASTROENTEROLOGY
- Claudin 2 Deficiency Reduces Bile Flow and Increases Susceptibility to Cholesterol Gallstone Disease in Mice
- (2014) Kengo Matsumoto et al. GASTROENTEROLOGY
- Extrahepatic Platelet-Derived Growth Factor-β, Delivered by Platelets, Promotes Activation of Hepatic Stellate Cells and Biliary Fibrosis in Mice
- (2014) Shuhei Yoshida et al. GASTROENTEROLOGY
- TGR5 reduces macrophage migration through mTOR-induced C/EBPβ differential translation
- (2014) Alessia Perino et al. JOURNAL OF CLINICAL INVESTIGATION
- Aberrant DNA methylation of G-protein-coupled bile acid receptor Gpbar1 predicts prognosis of acute-on-chronic hepatitis B liver failure
- (2014) S. Gao et al. JOURNAL OF VIRAL HEPATITIS
- Elevated Liver Regeneration in Response to Pharmacological Reduction of Elevated Portal Venous Pressure by Terlipressin After Partial Hepatectomy
- (2014) René Fahrner et al. TRANSPLANTATION
- Role of Bile Acids in Liver Injury and Regeneration following Acetaminophen Overdose
- (2013) Bharat Bhushan et al. AMERICAN JOURNAL OF PATHOLOGY
- Bile Acid Receptor TGR5 Agonism Induces NO Production and Reduces Monocyte Adhesion in Vascular Endothelial Cells
- (2013) Taiki Kida et al. ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY
- A systematic review: Burden and severity of subclinical cardiovascular disease among those with nonalcoholic fatty liver; Should we care?
- (2013) Ebenezer T. Oni et al. ATHEROSCLEROSIS
- Systemic bile acid sensing by G protein-coupled bile acid receptor 1 (GPBAR1) promotes PYY and GLP-1 release
- (2013) C Ullmer et al. BRITISH JOURNAL OF PHARMACOLOGY
- The receptor TGR5 protects the liver from bile acid overload during liver regeneration in mice
- (2013) Noémie Péan et al. HEPATOLOGY
- Repeated Oral Administration of Oleanolic Acid Produces Cholestatic Liver Injury in Mice
- (2013) Yuan-Fu Lu et al. MOLECULES
- Lipopolysaccharide Preconditioning Protects Hepatocytes from Ischemia/Reperfusion Injury (IRI) through Inhibiting ATF4-CHOP Pathway in Mice
- (2013) Jianhua Rao et al. PLoS One
- Glucagon-like peptide-1 receptor agonism improves metabolic, biochemical, and histopathological indices of nonalcoholic steatohepatitis in mice
- (2012) James L. Trevaskis et al. AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY
- Expression of bile acid receptor TGR5 in gastric adenocarcinoma
- (2012) Weibiao Cao et al. AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY
- Chenodeoxycholic acid through a TGR5-dependent CREB signaling activation enhances Cyclin D1 expression and promotes human endometrial cancer cell proliferation
- (2012) Ivan Casaburi et al. CELL CYCLE
- Guidelines for the diagnosis and treatment of cholangiocarcinoma: an update
- (2012) Shahid A Khan et al. GUT
- Nonalcoholic fatty liver disease is associated with coronary artery calcification
- (2012) Donghee Kim et al. HEPATOLOGY
- β-catenin regulates innate and adaptive immunity in mouse liver ischemia-reperfusion injury
- (2012) Bibo Ke et al. HEPATOLOGY
- HBV promotes the proliferation of hepatic stellate cells via the PDGF-B/PDGFR-β signaling pathway in vitro
- (2012) QIXUAN BAI et al. INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE
- Bile acid transporters and regulatory nuclear receptors in the liver and beyond
- (2012) Emina Halilbasic et al. JOURNAL OF HEPATOLOGY
- GLP-1 receptor agonists for individualized treatment of type 2 diabetes mellitus
- (2012) Juris J. Meier Nature Reviews Endocrinology
- Endoplasmic Reticulum Stress Modulates Liver Inflammatory Immune Response in the Pathogenesis of Liver Ischemia and Reperfusion Injury
- (2012) Jun Liu et al. TRANSPLANTATION
- Perspective: TGR5 (Gpbar-1) in liver physiology and disease
- (2012) Verena Keitel et al. Clinics and Research in Hepatology and Gastroenterology
- Current strategies to minimize hepatic ischemia–reperfusion injury by targeting reactive oxygen species
- (2012) Hartmut Jaeschke et al. Transplantation Reviews
- Glp-1 analog, liraglutide, ameliorates hepatic steatosis and cardiac hypertrophy in C57BL/6J mice fed a Western diet
- (2011) Jamie E. Mells et al. AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY
- The G-Protein-coupled bile acid receptor, Gpbar1 (TGR5), negatively regulates hepatic inflammatory response through antagonizing nuclear factor kappa light-chain enhancer of activated B cells (NF-κB) in mice
- (2011) Yan-Dong Wang et al. HEPATOLOGY
- Plasma MicroRNA Panel to Diagnose Hepatitis B Virus–Related Hepatocellular Carcinoma
- (2011) Jian Zhou et al. JOURNAL OF CLINICAL ONCOLOGY
- The G Protein-Coupled Bile Acid Receptor, TGR5, Stimulates Gallbladder Filling
- (2011) Tingting Li et al. MOLECULAR ENDOCRINOLOGY
- The biliary HCO3− umbrella: A unifying hypothesis on pathogenetic and therapeutic aspects of fibrosing cholangiopathies
- (2010) Ulrich Beuers et al. HEPATOLOGY
- Innate immunity and primary biliary cirrhosis: Activated invariant natural killer T cells exacerbate murine autoimmune cholangitis and fibrosis
- (2010) Si-Jie Wu et al. HEPATOLOGY
- Anti-PDGF-B monoclonal antibody reduces liver fibrosis development
- (2010) Shinji Ogawa et al. HEPATOLOGY RESEARCH
- Sustained repression and translocation of Ntcp and expression of Mrp4 for cholestasis after rat 90% partial hepatectomy
- (2010) Takuya Miura et al. JOURNAL OF HEPATOLOGY
- CD1d-restricted natural killer T cells contribute to hepatic inflammation and fibrogenesis in mice
- (2010) Sachiko Ishikawa et al. JOURNAL OF HEPATOLOGY
- Mutational Characterization of the Bile Acid Receptor TGR5 in Primary Sclerosing Cholangitis
- (2010) Johannes R. Hov et al. PLoS One
- The membrane-bound bile acid receptor TGR5 is localized in the epithelium of human gallbladders
- (2009) Verena Keitel et al. HEPATOLOGY
- Role of Wnt/β-catenin signaling in liver metabolism and cancer
- (2009) Satdarshan Pal Singh Monga INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY
- MicroRNA Expression, Survival, and Response to Interferon in Liver Cancer
- (2009) Junfang Ji et al. NEW ENGLAND JOURNAL OF MEDICINE
- Senescence of Activated Stellate Cells Limits Liver Fibrosis
- (2008) Valery Krizhanovsky et al. CELL
- Increased risk of cardiovascular disease in non-alcoholic fatty liver disease: causal effect or epiphenomenon?
- (2008) G. Targher et al. DIABETOLOGIA
- Foetal ‘flat’ bile acids reappear during human liver regeneration after surgery
- (2008) P. Stärkel et al. EUROPEAN JOURNAL OF CLINICAL INVESTIGATION
- PDGF-Receptor β-Targeted Adenovirus Redirects Gene Transfer from Hepatocytes to Activated Stellate Cells
- (2008) Marieke H. Schoemaker et al. MOLECULAR PHARMACEUTICS
Create your own webinar
Interested in hosting your own webinar? Check the schedule and propose your idea to the Peeref Content Team.
Create NowAsk a Question. Answer a Question.
Quickly pose questions to the entire community. Debate answers and get clarity on the most important issues facing researchers.
Get Started