Vertical sleeve gastrectomy activates GPBAR-1/TGR5 to sustain weight loss, improve fatty liver, and remit insulin resistance in mice

The Bile Acid Chenodeoxycholic Acid Increases Human Brown Adipose Tissue Activity

(2015) Evie P.M. Broeders et al.   Cell Metabolism

The regulation of function, growth and survival of GLP-1-producing L-cells

(2015) R. E. Kuhre et al.   CLINICAL SCIENCE

Bile Acids Trigger GLP-1 Release Predominantly by Accessing Basolaterally Located G Protein–Coupled Bile Acid Receptors

(2015) Cheryl A. Brighton et al.   ENDOCRINOLOGY

TGR5 contributes to glucoregulatory improvements after vertical sleeve gastrectomy in mice

(2015) Anne K McGavigan et al.   GUT

Bile diversion to the distal small intestine has comparable metabolic benefits to bariatric surgery

(2015) Charles Robb Flynn et al.   Nature Communications

The role of small heterodimer partner in nonalcoholic fatty liver disease improvement after sleeve gastrectomy in mice

(2015) Andriy Myronovych et al.   Obesity

Bile acids and the gut microbiome

(2014) Jason M. Ridlon et al.   CURRENT OPINION IN GASTROENTEROLOGY

The bile acid TGR5 membrane receptor: From basic research to clinical application

(2014) Henri Duboc et al.   DIGESTIVE AND LIVER DISEASE

Changes in Bariatric Surgery Procedure Use in Michigan, 2006-2013

(2014) Bradley N. Reames et al.   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

Intestinal farnesoid X receptor signaling promotes nonalcoholic fatty liver disease

(2014) Changtao Jiang et al.   JOURNAL OF CLINICAL INVESTIGATION

FXR is a molecular target for the effects of vertical sleeve gastrectomy

(2014) Karen K. Ryan et al.   NATURE

Beyond intestinal soap—bile acids in metabolic control

(2014) Folkert Kuipers et al.   Nature Reviews Endocrinology

The Comparative Effectiveness of Sleeve Gastrectomy, Gastric Bypass, and Adjustable Gastric Banding Procedures for the Treatment of Morbid Obesity

(2013) Arthur M. Carlin et al.   ANNALS OF SURGERY

Vertical Sleeve Gastrectomy Is Effective in Two Genetic Mouse Models of Glucagon-Like Peptide 1 Receptor Deficiency

(2013) H. E. Wilson-Perez et al.   DIABETES

Muricholic bile acids are potent regulators of bile acid synthesis via a positive feedback mechanism

(2013) X. Hu et al.   JOURNAL OF INTERNAL MEDICINE

Mechanisms underlying weight loss after bariatric surgery

(2013) Alexander D. Miras et al.   Nature Reviews Gastroenterology & Hepatology

Vertical sleeve gastrectomy reduces hepatic steatosis while increasing serum bile acids in a weight-loss-independent manner

(2013) Andriy Myronovych et al.   Obesity

Bile acids and gut peptide secretion after bariatric surgery: A 1-year prospective randomized pilot trial

(2013) Robert E. Steinert et al.   Obesity

Increased bile acids in enterohepatic circulation by short-term calorie restriction in male mice

(2013) Zidong Donna Fu et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

Microbiome remodelling leads to inhibition of intestinal farnesoid X receptor signalling and decreased obesity

(2013) Fei Li et al.   Nature Communications

All Bariatric Surgeries Are Not Created Equal: Insights from Mechanistic Comparisons

(2012) Margaret A. Stefater et al.   ENDOCRINE REVIEWS

Kv4.2 knockout mice have hippocampal-dependent learning and memory deficits

(2012) J. N. Lugo et al.   LEARNING & MEMORY

Functional interactions between the gut microbiota and host metabolism

(2012) Valentina Tremaroli et al.   NATURE

TGR5 potentiates GLP-1 secretion in response to anionic exchange resins

(2012) Taoufiq Harach et al.   Scientific Reports

Inhibition of SREBP by a Small Molecule, Betulin, Improves Hyperlipidemia and Insulin Resistance and Reduces Atherosclerotic Plaques

(2011) Jing-Jie Tang et al.   Cell Metabolism

GLP-1 and energy balance: an integrated model of short-term and long-term control

(2011) Jason G. Barrera et al.   Nature Reviews Endocrinology

Forming functional fat: a growing understanding of adipocyte differentiation

(2011) Ana G. Cristancho et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Bacterial biogeography of the human digestive tract

(2011) Jennifer C. Stearns et al.   Scientific Reports

Absence of Thyroid Hormone Activation during Development Underlies a Permanent Defect in Adaptive Thermogenesis

(2010) Jessica A. Hall et al.   ENDOCRINOLOGY

Presence of a functional receptor for GLP-1 in osteoblastic cells, independent of the cAMP-linked GLP-1 receptor

(2010) Bernardo Nuche-Berenguer et al.   JOURNAL OF CELLULAR PHYSIOLOGY

Improvement in Glucose Metabolism After Bariatric Surgery: Comparison of Laparoscopic Roux-en-Y Gastric Bypass and Laparoscopic Sleeve Gastrectomy

(2009) Ralph Peterli et al.   ANNALS OF SURGERY

TGR5-Mediated Bile Acid Sensing Controls Glucose Homeostasis

(2009) Charles Thomas et al.   Cell Metabolism

Serum Bile Acids Are Higher in Humans With Prior Gastric Bypass: Potential Contribution to Improved Glucose and Lipid Metabolism

(2009) Mary-Elizabeth Patti et al.   Obesity

Systematic review of sleeve gastrectomy as staging and primary bariatric procedure

(2009) Stacy A. Brethauer et al.   Surgery for Obesity and Related Diseases

Insulin-like actions of glucagon-like peptide-1: a dual receptor hypothesis

(2009) Eva Tomas et al.   TRENDS IN ENDOCRINOLOGY AND METABOLISM

Bile Acids Metabonomic Study on the CCl4- and α-Naphthylisothiocyanate-Induced Animal Models: Quantitative Analysis of 22 Bile Acids by Ultraperformance Liquid Chromatography−Mass Spectrometry

(2008) Li Yang et al.   CHEMICAL RESEARCH IN TOXICOLOGY