Oral Administration of Gintonin Protects the Brains of Mice against Aβ-Induced Alzheimer Disease Pathology: Antioxidant and Anti-Inflammatory Effects

Oral Administration of Alpha Linoleic Acid Rescues Aβ-Induced Glia-Mediated Neuroinflammation and Cognitive Dysfunction in C57BL/6N Mice

(2020) Waqar Ali et al.   Cells

Ongoing Research on the Role of Gintonin in the Management of Neurodegenerative Disorders

(2020) Muhammad Ikram et al.   Cells

Biological evidence of gintonin efficacy in memory disorders

(2020) Md. Jakaria et al.   PHARMACOLOGICAL RESEARCH

Hesperetin, a Citrus Flavonoid, Attenuates LPS-Induced Neuroinflammation, Apoptosis and Memory Impairments by Modulating TLR4/NF-κB Signaling

(2019) Tahir Muhammad et al.   Nutrients

Hesperetin Confers Neuroprotection by Regulating Nrf2/TLR4/NF-κB Signaling in an Aβ Mouse Model

(2019) Muhammad Ikram et al.   MOLECULAR NEUROBIOLOGY

Natural Dietary Supplementation of Curcumin Protects Mice Brains against Ethanol-Induced Oxidative Stress-Mediated Neurodegeneration and Memory Impairment via Nrf2/TLR4/RAGE Signaling

(2019) Muhammad Ikram et al.   Nutrients

Caffeine Modulates Cadmium-Induced Oxidative Stress, Neuroinflammation, and Cognitive Impairments by Regulating Nrf-2/HO-1 In Vivo and In Vitro

(2019) Amjad Khan et al.   Journal of Clinical Medicine

Neurological Enhancement Effects of Melatonin against Brain Injury-Induced Oxidative Stress, Neuroinflammation, and Neurodegeneration via AMPK/CREB Signaling

(2019) Shafiq Ur Rehman et al.   Cells

Gintonin Mitigates MPTP-Induced Loss of Nigrostriatal Dopaminergic Neurons and Accumulation of α-Synuclein via the Nrf2/HO-1 Pathway

(2018) Min Gi Jo et al.   MOLECULAR NEUROBIOLOGY

Multi-Target Protective Effects of Gintonin in 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine-Mediated Model of Parkinson’s Disease via Lysophosphatidic Acid Receptors

(2018) Jong Hee Choi et al.   Frontiers in Pharmacology

Oxidative stress and the amyloid beta peptide in Alzheimer’s disease

(2018) C. Cheignon et al.   Redox Biology

Melatonin Rescue Oxidative Stress-Mediated Neuroinflammation/ Neurodegeneration and Memory Impairment in Scopolamine-Induced Amnesia Mice Model

(2018) Tahir Muhammad et al.   Journal of Neuroimmune Pharmacology

Neuroprotective Effect of Quercetin Against the Detrimental Effects of LPS in the Adult Mouse Brain

(2018) Amjad Khan et al.   Frontiers in Pharmacology

NRF2 and NF-қB interplay in cerebrovascular and neurodegenerative disorders: Molecular mechanisms and possible therapeutic approaches

(2018) Farzane Sivandzade et al.   Redox Biology

Natural Dietary Supplementation of Anthocyanins via PI3K/Akt/Nrf2/HO-1 Pathways Mitigate Oxidative Stress, Neurodegeneration, and Memory Impairment in a Mouse Model of Alzheimer’s Disease

(2017) Tahir Ali et al.   MOLECULAR NEUROBIOLOGY

Vanillic acid attenuates Aβ1-42-induced oxidative stress and cognitive impairment in mice

(2017) Faiz Ul Amin et al.   Scientific Reports

Novel osmotin inhibits SREBP2 via the AdipoR1/AMPK/SIRT1 pathway to improve Alzheimer’s disease neuropathological deficits

(2016) S A Shah et al.   MOLECULAR PSYCHIATRY

PARP-1 inhibition influences the oxidative stress response of the human lens

(2016) Andrew J.O. Smith et al.   Redox Biology

Significance of NF-κB as a pivotal therapeutic target in the neurodegenerative pathologies of Alzheimer’s disease and multiple sclerosis

(2015) Mythily Srinivasan et al.   EXPERT OPINION ON THERAPEUTIC TARGETS

Synaptic enhancement induced by gintonin via lysophosphatidic acid receptor activation in central synapses

(2015) Hoyong Park et al.   JOURNAL OF NEUROPHYSIOLOGY

Neuroinflammation in Alzheimer's disease

(2015) Michael T Heneka et al.   LANCET NEUROLOGY

Oral Administration of Gintonin Attenuates Cholinergic Impairments by Scopolamine, Amyloid-β Protein, and Mouse Model of Alzheimer’s Disease

(2015) Hyeon-Joong Kim et al.   MOLECULES AND CELLS

NF-kappaB Signaling Pathways in Neurological Inflammation: A Mini Review

(2015) Ruey-Horng Shih et al.   Frontiers in Molecular Neuroscience

The Transcription Factor Nrf2 Is a Therapeutic Target against Brain Inflammation

(2014) N. G. Innamorato et al.   JOURNAL OF IMMUNOLOGY

Nrf2 Regulates Neurogenesis and Protects Neural Progenitor Cells Against Aβ Toxicity

(2014) Virve Kärkkäinen et al.   STEM CELLS

Yin and Yang of ginseng pharmacology: ginsenosides vs gintonin

(2013) Dong-soon Im et al.   ACTA PHARMACOLOGICA SINICA

Nrf2 impacts cellular bioenergetics by controlling substrate availability for mitochondrial respiration

(2013) K. M. Holmstrom et al.   Biology Open

Amyloid β-Peptide (1–42)-Induced Oxidative Stress in Alzheimer Disease: Importance in Disease Pathogenesis and Progression

(2012) D. Allan Butterfield et al.   ANTIOXIDANTS & REDOX SIGNALING

Gintonin, a ginseng-derived novel ingredient, evokes long-term potentiation through N-methyl-D-aspartic acid receptor activation: Involvement of LPA receptors

(2012) Tae-Joon Shin et al.   MOLECULES AND CELLS

Synaptic changes in Alzheimer’s disease and its models

(2012) J. Pozueta et al.   NEUROSCIENCE

Neuroprotective effect of Nrf2/ARE activators, CDDO ethylamide and CDDO trifluoroethylamide, in a mouse model of amyotrophic lateral sclerosis

(2011) Arie Neymotin et al.   FREE RADICAL BIOLOGY AND MEDICINE

A single NFκB system for both canonical and non-canonical signaling

(2010) Vincent Feng-Sheng Shih et al.   CELL RESEARCH

The selective autophagy substrate p62 activates the stress responsive transcription factor Nrf2 through inactivation of Keap1

(2010) Masaaki Komatsu et al.   NATURE CELL BIOLOGY

NF-κB regulation: the nuclear response

(2009) Arun K. Mankan et al.   JOURNAL OF CELLULAR AND MOLECULAR MEDICINE

Intrahippocampal injection of a lentiviral vector expressing Nrf2 improves spatial learning in a mouse model of Alzheimer's disease

(2009) K. Kanninen et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA