Melatonin Rescue Oxidative Stress-Mediated Neuroinflammation/ Neurodegeneration and Memory Impairment in Scopolamine-Induced Amnesia Mice Model

Scopolamine-Induced Memory Impairment Is Alleviated by Xanthotoxin: Role of Acetylcholinesterase and Oxidative Stress Processes

(2018) Krystyna Skalicka-Wozniak et al.   ACS Chemical Neuroscience

Ethanol Extract of Oldenlandia diffusa Herba Attenuates Scopolamine-Induced Cognitive Impairments in Mice via Activation of BDNF, P-CREB and Inhibition of Acetylcholinesterase

(2018) Jung Lee et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Long-Term Overexpression of Heme Oxygenase 1 Promotes Tau Aggregation in Mouse Brain by Inducing Tau Phosphorylation

(2018) Yang Hui et al.   JOURNAL OF ALZHEIMERS DISEASE

Low-Dose Aspirin Upregulates Tyrosine Hydroxylase and Increases Dopamine Production in Dopaminergic Neurons: Implications for Parkinson’s Disease

(2018) Suresh B. Rangasamy et al.   Journal of Neuroimmune Pharmacology

Inhibition of Autophagy Promotes Salinomycin-Induced Apoptosis via Reactive Oxygen Species-Mediated PI3K/AKT/mTOR and ERK/p38 MAPK-Dependent Signaling in Human Prostate Cancer Cells

(2017) Kwang-Youn Kim et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Chronic Silymarin, Quercetin and Naringenin Treatments Increase Monoamines Synthesis and Hippocampal Sirt1 Levels Improving Cognition in Aged Rats

(2017) F. Sarubbo et al.   Journal of Neuroimmune Pharmacology

Angiotensin II Receptor Blockers Attenuate Lipopolysaccharide-Induced Memory Impairment by Modulation of NF-κB-Mediated BDNF/CREB Expression and Apoptosis in Spontaneously Hypertensive Rats

(2017) Ruby Goel et al.   MOLECULAR NEUROBIOLOGY

17β-Estradiol via SIRT1/Acetyl-p53/NF-kB Signaling Pathway Rescued Postnatal Rat Brain Against Acute Ethanol Intoxication

(2017) Mehtab Khan et al.   MOLECULAR NEUROBIOLOGY

Spirulina maxima Extract Prevents Neurotoxicity via Promoting Activation of BDNF/CREB Signaling Pathways in Neuronal Cells and Mice

(2017) Eun-Jeong Koh et al.   MOLECULES

Lithium ameliorates lipopolysaccharide-induced neurotoxicity in the cortex and hippocampus of the adult rat brain

(2017) Muhammad Sohail Khan et al.   NEUROCHEMISTRY INTERNATIONAL

Vitis labruscana leaf extract ameliorates scopolamine-induced impairments with activation of Akt, ERK and CREB in mice

(2017) Ramesh Pariyar et al.   PHYTOMEDICINE

Vanillic acid attenuates Aβ1-42-induced oxidative stress and cognitive impairment in mice

(2017) Faiz Ul Amin et al.   Scientific Reports

Constant Illumination Induces Alzheimer-Like Damages with Endoplasmic Reticulum Involvement and the Protection of Melatonin

(2017) Zhi-Qun Ling et al.   JOURNAL OF ALZHEIMERS DISEASE

Scopolamine-induced greater alterations in neurochemical profile and increased oxidative stress demonstrated a better model of dementia: A comparative study

(2016) Saida Haider et al.   BRAIN RESEARCH BULLETIN

Efficacy of N-Acetylserotonin and Melatonin in the EAE Model of Multiple Sclerosis

(2016) Jie Wen et al.   Journal of Neuroimmune Pharmacology

Cathepsin B Improves ß-Amyloidosis and Learning and Memory in Models of Alzheimer’s Disease

(2016) Christine M Embury et al.   Journal of Neuroimmune Pharmacology

A Novel Aβ B-Cell Epitope Vaccine (rCV01) for Alzheimer’s Disease Improved Synaptic and Cognitive Functions in 3 × Tg-AD Mice

(2016) Yun-Zhou Yu et al.   Journal of Neuroimmune Pharmacology

Astaxanthin Inhibits Acetaldehyde-Induced Cytotoxicity in SH-SY5Y Cells by Modulating Akt/CREB and p38MAPK/ERK Signaling Pathways

(2016) Tingting Yan et al.   Marine Drugs

The Protective Role of Selenium on Scopolamine-Induced Memory Impairment, Oxidative Stress, and Apoptosis in Aged Rats: The Involvement of TRPM2 and TRPV1 Channels

(2016) Hasan Balaban et al.   MOLECULAR NEUROBIOLOGY

Lactucopicrin ameliorates oxidative stress mediated by scopolamine-induced neurotoxicity through activation of the NRF2 pathway

(2016) Ramu Venkatesan et al.   NEUROCHEMISTRY INTERNATIONAL

Glycine inhibits ethanol-induced oxidative stress, neuroinflammation and apoptotic neurodegeneration in postnatal rat brain

(2016) Faiz Ul Amin et al.   NEUROCHEMISTRY INTERNATIONAL

Deer Bone Extract Prevents Against Scopolamine-Induced Memory Impairment in Mice

(2015) Chun Nan Du et al.   JOURNAL OF MEDICINAL FOOD

Protective Effect of Lupeol Against Lipopolysaccharide-Induced Neuroinflammation via the p38/c-Jun N-Terminal Kinase Pathway in the Adult Mouse Brain

(2015) Haroon Badshah et al.   Journal of Neuroimmune Pharmacology

Melatonin ameliorates amyloid beta-induced memory deficits, tau hyperphosphorylation and neurodegeneration via PI3/Akt/GSk3β pathway in the mouse hippocampus

(2015) Tahir Ali et al.   JOURNAL OF PINEAL RESEARCH

Osmotin attenuates amyloid beta-induced memory impairment, tau phosphorylation and neurodegeneration in the mouse hippocampus

(2015) Tahir Ali et al.   Scientific Reports

Bushen-Yizhi formula ameliorates cognition deficits and attenuates oxidative stress-related neuronal apoptosis in scopolamine-induced senescence in mice

(2014) XUE-QIN HOU et al.   INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE

2-Cyclopropylimino-3-Methyl-1,3-Thiazoline Hydrochloride Inhibits Microglial Activation by Suppression of Nuclear Factor-Kappa B and Mitogen-Activated Protein Kinase Signaling

(2014) Eun-A Kim et al.   Journal of Neuroimmune Pharmacology

Brain-Derived Neurotrophic Factor in Alzheimer’s Disease: Risk, Mechanisms, and Therapy

(2014) Jing-Hui Song et al.   MOLECULAR NEUROBIOLOGY

Long-term administration of scopolamine interferes with nerve cell proliferation, differentiation and migration in adult mouse hippocampal dentate gyrus, but it does not induce cell death

(2014) Il-Jun Kang et al.   Neural Regeneration Research

The Intersection of Amyloid Beta and Tau at Synapses in Alzheimer’s Disease

(2014) Tara L. Spires-Jones et al.   NEURON

Cholinergic receptor blockade by scopolamine and mecamylamine exacerbates global cerebral ischemia induced memory dysfunction in C57BL/6J mice

(2014) R.S. Ray et al.   NITRIC OXIDE-BIOLOGY AND CHEMISTRY

Effects of imperatorin on scopolamine-induced cognitive impairment and oxidative stress in mice

(2014) Barbara Budzynska et al.   PSYCHOPHARMACOLOGY

Genome-wide microRNA expression profiles in hippocampus of rats with chronic temporal lobe epilepsy

(2014) Meng-Meng Li et al.   Scientific Reports

The effect of Ginkgo biloba extract on scopolamine-induced apoptosis in the hippocampus of rats

(2013) M. Jahanshahi et al.   ANATOMICAL SCIENCE INTERNATIONAL

Meserine, a Novel Carbamate AChE Inhibitor, Ameliorates Scopolamine-Induced Dementia and Alleviates Amyloidogenesis of APP/PS1 Transgenic Mice

(2013) Bi-Yun Shao et al.   CNS Neuroscience & Therapeutics

Up-Regulation of Neurotrophic Factors by Cinnamon and its Metabolite Sodium Benzoate: Therapeutic Implications for Neurodegenerative Disorders

(2013) Arundhati Jana et al.   Journal of Neuroimmune Pharmacology

Sustained, neuron-specific IKK/NF-κB activation generates a selective neuroinflammatory response promoting local neurodegeneration with aging

(2013) Ayesha Maqbool et al.   Molecular Neurodegeneration

Protective Effects of Mangosteen Extract on H2O2-Induced Cytotoxicity in SK-N-SH Cells and Scopolamine-Induced Memory Impairment in Mice

(2013) Jintana Sattayasai et al.   PLoS One

JNK modulates FOXO3a for the expression of the mitochondrial death and mitophagy marker BNIP3 in pathological hypertrophy and in heart failure

(2012) A H Chaanine et al.   Cell Death & Disease

Cyclic AMP response element-binding protein (CREB) phosphorylation: A mechanistic marker in the development of memory enhancing Alzheimer's disease therapeutics

(2011) R. Scott Bitner   BIOCHEMICAL PHARMACOLOGY

Safety and tolerability of donepezil 23 mg in moderate to severe Alzheimer's disease

(2011) Martin Farlow et al.   BMC Neurology

The ameliorating effects of stigmasterol on scopolamine-induced memory impairments in mice

(2011) Se Jin Park et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Effects of Obovatol on GSH Depleted Glia-Mediated Neurotoxicity and Oxidative Damage

(2011) Moonhee Lee et al.   Journal of Neuroimmune Pharmacology

Hormesis, cellular stress response and vitagenes as critical determinants in aging and longevity

(2011) Vittorio Calabrese et al.   MOLECULAR ASPECTS OF MEDICINE

Protective Role of Ashwagandha Leaf Extract and Its Component Withanone on Scopolamine-Induced Changes in the Brain and Brain-Derived Cells

(2011) Arpita Konar et al.   PLoS One

The cholinergic system in aging and neuronal degeneration

(2010) Reinhard Schliebs et al.   BEHAVIOURAL BRAIN RESEARCH

Melatonin agonists and insomnia

(2010) Sally A Ferguson et al.   Expert Review of Neurotherapeutics

Amyloid-β neurotoxicity in organotypic culture is attenuated by melatonin: involvement of GSK-3β,tauand neuroinflammation

(2010) Juliana Bender Hoppe et al.   JOURNAL OF PINEAL RESEARCH

Purple Sweet Potato Color Alleviates D-galactose-induced Brain Aging in Old Mice by Promoting Survival of Neurons via PI3K Pathway and Inhibiting Cytochrome C-mediated Apoptosis

(2009) Jun Lu et al.   BRAIN PATHOLOGY

Inflammation and Microglia Actions in Alzheimer’s Disease

(2009) Colin K. Combs   Journal of Neuroimmune Pharmacology

Chitosan prevents oxidative stress-induced amyloid β formation and cytotoxicity in NT2 neurons: involvement of transcription factors Nrf2 and NF-κB

(2009) Fariba Khodagholi et al.   MOLECULAR AND CELLULAR BIOCHEMISTRY

Insulin neuroprotection against oxidative stress is mediated by Akt and GSK-3β signaling pathways and changes in protein expression

(2008) Ana I. Duarte et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH