Neuroendocrine, neuroinflammatory and pathological outcomes of chronic stress: A story of microglial remodeling

Microglia polarization of hippocampus is involved in the mechanism of Apelin-13 ameliorating chronic water immersion restraint stress-induced depression-like behavior in rats

(2020) Shouhong Zhou et al.   NEUROPEPTIDES

Role of oxidative stress in depression

(2020) Shvetank Bhatt et al.   DRUG DISCOVERY TODAY

Microglial physiological properties and interactions with synapses are altered at presymptomatic stages in a mouse model of Huntington’s disease pathology

(2020) Julie C. Savage et al.   Journal of Neuroinflammation

Diazepam limits microglia-mediated neuronal remodeling in the prefrontal cortex and associated behavioral consequences following chronic unpredictable stress

(2020) Justin L. Bollinger et al.   NEUROPSYCHOPHARMACOLOGY

A single administration of the antibiotic, minocycline, reduces fear processing and improves implicit learning in healthy volunteers: analysis of the serum metabolome

(2020) Shi Yu Chan et al.   Translational Psychiatry

Therapeutic modulation of inflammasome pathways

(2020) Dhruv Chauhan et al.   IMMUNOLOGICAL REVIEWS

Ketamine/xylazine and barbiturates modulate microglial morphology and motility differently in a mouse model

(2020) Ines Hristovska et al.   PLoS One

PPARγ-mediated microglial activation phenotype is involved in depressive-like behaviors and neuroinflammation in stressed C57BL/6J and ob/ob mice

(2020) Xiaqing Qin et al.   PSYCHONEUROENDOCRINOLOGY

Negative feedback control of neuronal activity by microglia

(2020) Ana Badimon et al.   NATURE

Remodeling microglia to a protective phenotype in Parkinson’s disease?

(2020) Ifeoluwa Oluleke Awogbindin et al.   NEUROSCIENCE LETTERS

Chronic unpredictable mild stress accelerates lipopolysaccharide- induced microglia activation and damage of dopaminergic neurons in rats

(2019) Hua Kong et al.   PHARMACOLOGY BIOCHEMISTRY AND BEHAVIOR

Longstanding psychological stress in relation to biomarkers of neuronal dysfunction in cerebrospinal fluid: A 25-year follow-up study in women

(2019) Lena Johansson et al.   NEUROBIOLOGY OF AGING

Cell-Type-Specific Interleukin 1 Receptor 1 Signaling in the Brain Regulates Distinct Neuroimmune Activities

(2019) Xiaoyu Liu et al.   IMMUNITY

Repeated social defeat in female mice induces anxiety-like behavior associated with enhanced myelopoiesis and increased monocyte accumulation in the brain

(2019) Wenyuan Yin et al.   BRAIN BEHAVIOR AND IMMUNITY

Ultrastructural evidence of microglial heterogeneity in Alzheimer’s disease amyloid pathology

(2019) Hassan El Hajj et al.   Journal of Neuroinflammation

The behavioral sequelae of social defeat require microglia and are driven by oxidative stress in mice

(2019) Michael L. Lehmann et al.   JOURNAL OF NEUROSCIENCE

Sex differences in depressive-like behaviour may relate to imbalance of microglia activation in the hippocampus

(2019) Lin-Lin Liu et al.   BRAIN BEHAVIOR AND IMMUNITY

Interleukin-1 causes CNS inflammatory cytokine expression via endothelia-microglia bi-cellular signaling

(2019) Ling Zhu et al.   BRAIN BEHAVIOR AND IMMUNITY

Glucocorticoid receptor antagonism prevents microglia-mediated neuronal remodeling and behavioral despair following chronic unpredictable stress

(2019) Matthew J. Horchar et al.   BRAIN BEHAVIOR AND IMMUNITY

Gonadal hormones differentially regulate sex‐specific stress effects on glia in the medial prefrontal cortex

(2019) Justin L. Bollinger et al.   JOURNAL OF NEUROENDOCRINOLOGY

Neuronal impairment following chronic Toxoplasma gondii infection is aggravated by intestinal nematode challenge in an IFN-γ-dependent manner

(2019) Timothy French et al.   Journal of Neuroinflammation

Chronic mild stress induced anxiety-like behaviors can Be attenuated by inhibition of NOX2-derived oxidative stress

(2019) Hang Lv et al.   JOURNAL OF PSYCHIATRIC RESEARCH

Clostridium butyricum miyairi 588 has preventive effects on chronic social defeat stress-induced depressive-like behaviour and modulates microglial activation in mice

(2019) Tian Tian et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Phagocytic elimination of synapses by microglia during sleep

(2019) Mohammed E. Choudhury et al.   GLIA

3D cellular reconstruction of cortical glia and parenchymal morphometric analysis from Serial Block-Face Electron Microscopy of juvenile rat

(2019) Corrado Cali et al.   PROGRESS IN NEUROBIOLOGY

Glucocorticoid-Driven NLRP3 Inflammasome Activation in Hippocampal Microglia Mediates Chronic Stress-Induced Depressive-Like Behaviors

(2019) Xiujing Feng et al.   Frontiers in Molecular Neuroscience

Fighting the Fire: Mechanisms of Inflammatory Gene Regulation by the Glucocorticoid Receptor

(2019) Laura Escoter-Torres et al.   Frontiers in Immunology

Involvement of CX3CL1/CX3CR1 in depression and cognitive impairment induced by chronic unpredictable stress and relevant underlying mechanism

(2019) Ye Liu et al.   BEHAVIOURAL BRAIN RESEARCH

Neuronal network activity controls microglial process surveillance in awake mice via norepinephrine signaling

(2019) Yong U. Liu et al.   NATURE NEUROSCIENCE

Noradrenergic signaling in the wakeful state inhibits microglial surveillance and synaptic plasticity in the mouse visual cortex

(2019) Rianne D. Stowell et al.   NATURE NEUROSCIENCE

Increased interactions and engulfment of dendrites by microglia precede Purkinje cell degeneration in a mouse model of Niemann Pick Type-C

(2019) Larisa Kavetsky et al.   Scientific Reports

SRT2104 attenuates chronic unpredictable mild stress-induced depressive-like behaviors and imbalance between microglial M1 and M2 phenotypes in the mice

(2019) Chun-Mei Duan et al.   BEHAVIOURAL BRAIN RESEARCH

Neuroinflammation induced by secretion of acetylated HMGB1 from activated microglia in hippocampi of mice following chronic cold exposure

(2019) Bin Xu et al.   BRAIN RESEARCH

Glucocorticoid receptors modulate dendritic spine plasticity and microglia activity in an animal model of Alzheimer's disease

(2019) Matteo Pedrazzoli et al.   NEUROBIOLOGY OF DISEASE

Txnip mediates glucocorticoid-activated NLRP3 inflammatory signaling in mouse microglia

(2019) Veni Bharti et al.   NEUROCHEMISTRY INTERNATIONAL

Antidepressant effect of the translocator protein antagonist ONO-2952 on mouse behaviors under chronic social defeat stress

(2019) Kanako Nozaki et al.   NEUROPHARMACOLOGY

Minocycline ameliorates depressive behaviors and neuro-immune dysfunction induced by chronic unpredictable mild stress in the rat

(2018) Cai Zhang et al.   BEHAVIOURAL BRAIN RESEARCH

Opposite Molecular Signatures of Depression in Men and Women

(2018) Marianne L. Seney et al.   BIOLOGICAL PSYCHIATRY

Persistent Increase in Microglial RAGE Contributes to Chronic Stress–Induced Priming of Depressive-like Behavior

(2018) Tina C. Franklin et al.   BIOLOGICAL PSYCHIATRY

Glucocorticoid receptor in astrocytes regulates midbrain dopamine neurodegeneration through connexin hemichannel activity

(2018) Layal Maatouk et al.   CELL DEATH AND DIFFERENTIATION

Microglial interactions with the neurovascular system in physiology and pathology

(2018) Xiaoliang Zhao et al.   Developmental Neurobiology

Orexins and stress

(2018) Laura A. Grafe et al.   FRONTIERS IN NEUROENDOCRINOLOGY

Microglial activation mediates chronic mild stress-induced depressive- and anxiety-like behavior in adult rats

(2018) Ya-Lin Wang et al.   Journal of Neuroinflammation

Multiple Immune-Inflammatory and Oxidative and Nitrosative Stress Pathways Explain the Frequent Presence of Depression in Multiple Sclerosis

(2018) Gerwyn Morris et al.   MOLECULAR NEUROBIOLOGY

Molecular mechanism of noradrenaline during the stress-induced major depressive disorder

(2018) ManojKumar Jaiswal et al.   Neural Regeneration Research

Microglia Polarization and Endoplasmic Reticulum Stress in Chronic Social Defeat Stress Induced Depression Mouse

(2018) Jie Tang et al.   NEUROCHEMICAL RESEARCH

A P2X7 receptor antagonist reverses behavioural alterations, microglial activation and neuroendocrine dysregulation in an unpredictable chronic mild stress (UCMS) model of depression in mice

(2018) Rai Khalid Farooq et al.   PSYCHONEUROENDOCRINOLOGY

Psychological Stress and Mitochondria

(2018) Martin Picard et al.   PSYCHOSOMATIC MEDICINE

Vulnerability of glia and vessels of rat substantia nigra in rotenone Parkinson model

(2018) Sanaa A. M. Elgayar et al.   ULTRASTRUCTURAL PATHOLOGY

TLR9 activation via microglial glucocorticoid receptors contributes to degeneration of midbrain dopamine neurons

(2018) Layal Maatouk et al.   Nature Communications

Microglia remodel synapses by presynaptic trogocytosis and spine head filopodia induction

(2018) Laetitia Weinhard et al.   Nature Communications

Sex-Specific Features of Microglia from Adult Mice

(2018) Alessandro Villa et al.   Cell Reports

A Comprehensive Overview on Stress Neurobiology: Basic Concepts and Clinical Implications

(2018) Lívea Dornela Godoy et al.   Frontiers in Behavioral Neuroscience

Microglia Gone Rogue: Impacts on Psychiatric Disorders across the Lifespan

(2018) Tuan Leng Tay et al.   Frontiers in Molecular Neuroscience

Prenatal Immune Challenge in Mice Leads to Partly Sex-Dependent Behavioral, Microglial, and Molecular Abnormalities Associated with Schizophrenia

(2018) Chin W. Hui et al.   Frontiers in Molecular Neuroscience

Inflammasome signalling in brain function and neurodegenerative disease

(2018) Michael T. Heneka et al.   NATURE REVIEWS NEUROSCIENCE

Effects of Peripheral Immune Challenge on In Vivo Firing of Basolateral Amygdala Neurons in Adult Male Rats

(2018) Soumyabrata Munshi et al.   NEUROSCIENCE

Adverse Early Life Environment Induces Anxiety-like Behavior and Increases 2 Expression of FKBP5 mRNA Splice Variants in Mouse Brain

(2018) Xingrao Ke et al.   PHYSIOLOGICAL GENOMICS

The Corticotropin-Releasing Factor Family: Physiology of the Stress Response

(2018) Jan M. Deussing et al.   PHYSIOLOGICAL REVIEWS

Bidirectional Microglia–Neuron Communication in Health and Disease

(2018) Zsuzsanna Szepesi et al.   Frontiers in Cellular Neuroscience

Microglial Implication in Parkinson’s Disease: Loss of Beneficial Physiological Roles or Gain of Inflammatory Functions?

(2018) Cynthia Lecours et al.   Frontiers in Cellular Neuroscience

Decoding microglia responses to psychosocial stress reveals blood-brain barrier breakdown that may drive stress susceptibility

(2018) Michael L. Lehmann et al.   Scientific Reports

The Influence of Microglial Elimination and Repopulation on Stress Sensitization Induced by Repeated Social Defeat

(2018) Michael D. Weber et al.   BIOLOGICAL PSYCHIATRY

Interleukin-6 Induced by Social Stress Promotes a Unique Transcriptional Signature in the Monocytes That Facilitate Anxiety

(2018) Anzela Niraula et al.   BIOLOGICAL PSYCHIATRY

Partial reduction of microglia does not affect tau pathology in aged mice

(2018) Rachel E. Bennett et al.   Journal of Neuroinflammation

Global, regional, and national incidence, prevalence, and years lived with disability for 354 diseases and injuries for 195 countries and territories, 1990–2017: a systematic analysis for the Global Burden of Disease Study 2017

(2018) Spencer L James et al.   LANCET

Indoleamine 2,3-Dioxygenase-Dependent Neurotoxic Kynurenine Metabolism Contributes to Poststroke Depression Induced in Mice by Ischemic Stroke along with Spatial Restraint Stress

(2018) Young Soo Koo et al.   Oxidative Medicine and Cellular Longevity

Social Stress Mobilizes Hematopoietic Stem Cells to Establish Persistent Splenic Myelopoiesis

(2018) Daniel B. McKim et al.   Cell Reports

The TREM2-APOE Pathway Drives the Transcriptional Phenotype of Dysfunctional Microglia in Neurodegenerative Diseases

(2017) Susanne Krasemann et al.   IMMUNITY

Lack of interleukin-13 receptor α1 delays the loss of dopaminergic neurons during chronic stress

(2017) Simone Mori et al.   Journal of Neuroinflammation

Activation of P2X7 receptor and NLRP3 inflammasome assembly in hippocampal glial cells mediates chronic stress-induced depressive-like behaviors

(2017) Na Yue et al.   Journal of Neuroinflammation

Markers of microglia in post-mortem brain samples from patients with Alzheimer’s disease: a systematic review

(2017) K E Hopperton et al.   MOLECULAR PSYCHIATRY

Microglial recruitment of IL-1β-producing monocytes to brain endothelium causes stress-induced anxiety

(2017) D B McKim et al.   MOLECULAR PSYCHIATRY

Sex-specific transcriptional signatures in human depression

(2017) Benoit Labonté et al.   NATURE MEDICINE

Social stress induces neurovascular pathology promoting depression

(2017) Caroline Menard et al.   NATURE NEUROSCIENCE

Microglia Loss Contributes to the Development of Major Depression Induced by Different Types of Chronic Stresses

(2017) Lijuan Tong et al.   NEUROCHEMICAL RESEARCH

Major depressive disorder and anxiety disorders from the glial perspective: Etiological mechanisms, intervention and monitoring

(2017) Mari Sild et al.   NEUROSCIENCE AND BIOBEHAVIORAL REVIEWS

Chronic Variable Stress Is Responsible for Lipid and DNA Oxidative Disorders and Activation of Oxidative Stress Response Genes in the Brain of Rats

(2017) Mariola Herbet et al.   Oxidative Medicine and Cellular Longevity

Dynamic cross-talk between microglia and peripheral monocytes underlies stress-induced neuroinflammation and behavioral consequences

(2017) Eric S. Wohleb et al.   PROGRESS IN NEURO-PSYCHOPHARMACOLOGY & BIOLOGICAL PSYCHIATRY

Roles of Microglial Phagocytosis and Inflammatory Mediators in the Pathophysiology of Sleep Disorders

(2017) Agnes Nadjar et al.   Frontiers in Cellular Neuroscience

Coupled Proliferation and Apoptosis Maintain the Rapid Turnover of Microglia in the Adult Brain

(2017) Katharine Askew et al.   Cell Reports

Inflammation and vascular remodeling in the ventral hippocampus contributes to vulnerability to stress

(2017) J Pearson-Leary et al.   Translational Psychiatry

Behavioral stress alters corticolimbic microglia in a sex- and brain region-specific manner

(2017) Justin L. Bollinger et al.   PLoS One

Chronic restraint stress triggers dopaminergic and noradrenergic neurodegeneration: Possible role of chronic stress in the onset of Parkinson’s disease

(2016) Shuei Sugama et al.   BRAIN BEHAVIOR AND IMMUNITY

Dynamic microglial modulation of spatial learning and social behavior

(2016) Luisa Torres et al.   BRAIN BEHAVIOR AND IMMUNITY

Divergent effects of repeated restraint versus chronic variable stress on prefrontal cortical immune status after LPS injection

(2016) Brittany L. Smith et al.   BRAIN BEHAVIOR AND IMMUNITY

Fluoxetine treatment affects the inflammatory response and microglial function according to the quality of the living environment

(2016) Silvia Alboni et al.   BRAIN BEHAVIOR AND IMMUNITY

Divergent responses of inflammatory mediators within the amygdala and medial prefrontal cortex to acute psychological stress

(2016) Haley A. Vecchiarelli et al.   BRAIN BEHAVIOR AND IMMUNITY

Altered microglia morphology and higher resilience to stress-induced depression-like behavior in CX3CR1-deficient mice

(2016) Sabine Hellwig et al.   BRAIN BEHAVIOR AND IMMUNITY

Differential effects of stress on microglial cell activation in male and female medial prefrontal cortex

(2016) Justin L. Bollinger et al.   BRAIN BEHAVIOR AND IMMUNITY

Fractalkine receptor deficiency impairs microglial and neuronal responsiveness to chronic stress

(2016) Giampaolo Milior et al.   BRAIN BEHAVIOR AND IMMUNITY

Dark microglia: A new phenotype predominantly associated with pathological states

(2016) Kanchan Bisht et al.   GLIA

Social defeat induces depressive-like states and microglial activation without involvement of peripheral macrophages

(2016) Michael L. Lehmann et al.   Journal of Neuroinflammation

Danger Signals and Inflammasomes: Stress-Evoked Sterile Inflammation in Mood Disorders

(2016) Monika Fleshner et al.   NEUROPSYCHOPHARMACOLOGY

Stress-induced anhedonia is associated with the activation of the inflammatory system in the rat brain: Restorative effect of pharmacological intervention

(2016) Andrea C. Rossetti et al.   PHARMACOLOGICAL RESEARCH

Microglial P2Y12 is necessary for synaptic plasticity in mouse visual cortex

(2016) G. O. Sipe et al.   Nature Communications

Chronic Stress and Glucocorticoids: From Neuronal Plasticity to Neurodegeneration

(2016) Sheela Vyas et al.   NEURAL PLASTICITY

Dendritic Spines in Depression: What We Learned from Animal Models

(2016) Hui Qiao et al.   NEURAL PLASTICITY

Neuron–Microglia Interactions in Mental Health Disorders: “For Better, and For Worse”

(2016) Eric S. Wohleb   Frontiers in Immunology

Stress sounds the alarmin: The role of the danger-associated molecular pattern HMGB1 in stress-induced neuroinflammatory priming

(2015) Matthew G. Frank et al.   BRAIN BEHAVIOR AND IMMUNITY

Astrocyte and Microglial Control of Glutamatergic Signalling: A Primer on Understanding the Disruptive Role of Chronic Stress

(2015) J. Mayhew et al.   JOURNAL OF NEUROENDOCRINOLOGY

Complement C3-Deficient Mice Fail to Display Age-Related Hippocampal Decline

(2015) Q. Shi et al.   JOURNAL OF NEUROSCIENCE

Neuroinflammation in Alzheimer's disease

(2015) Michael T Heneka et al.   LANCET NEUROLOGY

Stress-Induced Depressive Behaviors Require a Functional NLRP3 Inflammasome

(2015) Elísabet Alcocer-Gómez et al.   MOLECULAR NEUROBIOLOGY

Activation and Regulation of NLRP3 Inflammasome by Intrathecal Application of SDF-1a in a Spinal Cord Injury Model

(2015) Adib Zendedel et al.   MOLECULAR NEUROBIOLOGY

Sex differences and stress across the lifespan

(2015) Tracy L Bale et al.   NATURE NEUROSCIENCE

Stress-related synaptic plasticity in the hypothalamus

(2015) Jaideep S. Bains et al.   NATURE REVIEWS NEUROSCIENCE

Stress Effects on Neuronal Structure: Hippocampus, Amygdala and Prefrontal Cortex

(2015) Bruce S McEwen et al.   NEUROPSYCHOPHARMACOLOGY

Social defeat promotes a reactive endothelium in a brain region-dependent manner with increased expression of key adhesion molecules, selectins and chemokines associated with the recruitment of myeloid cells to the brain

(2015) C.M. Sawicki et al.   NEUROSCIENCE

Peripheral and central effects of repeated social defeat stress: Monocyte trafficking, microglial activation, and anxiety

(2015) B.F. Reader et al.   NEUROSCIENCE

The development of depression-like behavior is consolidated by IL-6-induced activation of locus coeruleus neurons and IL-1β-induced elevated leptin levels in mice

(2015) Natsuki Kurosawa et al.   PSYCHOPHARMACOLOGY

Sleep and Alzheimer's disease

(2015) Laure Peter-Derex et al.   SLEEP MEDICINE REVIEWS

Circadian endocrine rhythms: the hypothalamic-pituitary-adrenal axis and its actions

(2014) Nicolas C. Nicolaides et al.   Annals of the New York Academy of Sciences

Microglial NLRP3 inflammasome activation mediates IL-1β-related inflammation in prefrontal cortex of depressive rats

(2014) Ying Pan et al.   BRAIN BEHAVIOR AND IMMUNITY

Evidence for increased microglial priming and macrophage recruitment in the dorsal anterior cingulate white matter of depressed suicides

(2014) Susana G. Torres-Platas et al.   BRAIN BEHAVIOR AND IMMUNITY

Oxidative Stress and Psychological Disorders

(2014) Samina Salim   Current Neuropharmacology

Effects of stress on immune function: the good, the bad, and the beautiful

(2014) Firdaus S. Dhabhar   IMMUNOLOGIC RESEARCH

Chronic stress enhances microglia activation and exacerbates death of nigral dopaminergic neurons under conditions of inflammation

(2014) Rocío M de Pablos et al.   Journal of Neuroinflammation

Knockdown of Interleukin-1 Receptor Type-1 on Endothelial Cells Attenuated Stress-Induced Neuroinflammation and Prevented Anxiety-Like Behavior

(2014) E. S. Wohleb et al.   JOURNAL OF NEUROSCIENCE

Activation of Neuronal NMDA Receptors Triggers Transient ATP-Mediated Microglial Process Outgrowth

(2014) L. Dissing-Olesen et al.   JOURNAL OF NEUROSCIENCE

Inflammasomes in the CNS

(2014) John G. Walsh et al.   NATURE REVIEWS NEUROSCIENCE

Are Sleep Disturbances Preclinical Markers of Parkinson’s Disease?

(2014) Altair B. dos Santos et al.   NEUROCHEMICAL RESEARCH

The Intersection of Amyloid Beta and Tau at Synapses in Alzheimer’s Disease

(2014) Tara L. Spires-Jones et al.   NEURON

Colony-Stimulating Factor 1 Receptor Signaling Is Necessary for Microglia Viability, Unmasking a Microglia Progenitor Cell in the Adult Brain

(2014) Monica R.P. Elmore et al.   NEURON

Fractalkine regulation of microglial physiology and consequences on the brain and behavior

(2014) Rosa Chiara Paolicelli et al.   Frontiers in Cellular Neuroscience

Chronic stress-induced disruption of the astrocyte network is driven by structural atrophy and not loss of astrocytes

(2013) Ross J. Tynan et al.   ACTA NEUROPATHOLOGICA

Re-establishment of Anxiety in Stress-Sensitized Mice Is Caused by Monocyte Trafficking from the Spleen to the Brain

(2013) Eric S. Wohleb et al.   BIOLOGICAL PSYCHIATRY

Chemokines and the hippocampus: A new perspective on hippocampal plasticity and vulnerability

(2013) Lauren L. Williamson et al.   BRAIN BEHAVIOR AND IMMUNITY

Exercise protects against chronic restraint stress-induced oxidative stress in the cortex and hippocampus

(2013) Kim M. Gerecke et al.   BRAIN RESEARCH

Microglia Promote Learning-Dependent Synapse Formation through Brain-Derived Neurotrophic Factor

(2013) Christopher N. Parkhurst et al.   CELL

Sleep and synaptic changes

(2013) Chiara Cirelli   CURRENT OPINION IN NEUROBIOLOGY

Microglia in normal appearing white matter of multiple sclerosis are alerted but immunosuppressed

(2013) Jeroen Melief et al.   GLIA

Stress-Induced Recruitment of Bone Marrow-Derived Monocytes to the Brain Promotes Anxiety-Like Behavior

(2013) E. S. Wohleb et al.   JOURNAL OF NEUROSCIENCE

A Dramatic Increase of C1q Protein in the CNS during Normal Aging

(2013) A. H. Stephan et al.   JOURNAL OF NEUROSCIENCE

Dynamic microglial alterations underlie stress-induced depressive-like behavior and suppressed neurogenesis

(2013) T Kreisel et al.   MOLECULAR PSYCHIATRY

Glucocorticoid-Related Molecular Signaling Pathways Regulating Hippocampal Neurogenesis

(2013) Christoph Anacker et al.   NEUROPSYCHOPHARMACOLOGY

Quercetin suppress microglial neuroinflammatory response and induce antidepressent-like effect in olfactory bulbectomized rats

(2013) P. Rinwa et al.   NEUROSCIENCE

Inflammatory cytokines in depression: Neurobiological mechanisms and therapeutic implications

(2013) J.C. Felger et al.   NEUROSCIENCE

Differential effects of homotypic vs. heterotypic chronic stress regimens on microglial activation in the prefrontal cortex

(2013) Brittany L. Kopp et al.   PHYSIOLOGY & BEHAVIOR

Bone Marrow-Derived Microglia Infiltrate into the Paraventricular Nucleus of Chronic Psychological Stress-Loaded Mice

(2013) Koji Ataka et al.   PLoS One

Chronic exposure to exogenous glucocorticoids primes microglia to pro-inflammatory stimuli and induces NLRP3 mRNA in the hippocampus

(2013) Matthew G. Frank et al.   PSYCHONEUROENDOCRINOLOGY

Direct Proteomic Quantification of the Secretome of Activated Immune Cells

(2013) F. Meissner et al.   SCIENCE

Microglia and macrophages of the central nervous system: the contribution of microglia priming and systemic inflammation to chronic neurodegeneration

(2013) V. Hugh Perry et al.   Seminars in Immunopathology

Janus-faced microglia: beneficial and detrimental consequences of microglial phagocytosis

(2013) Amanda Sierra et al.   Frontiers in Cellular Neuroscience

Stress and Sleep Disorder

(2013) Kuem Sun Han et al.   Experimental Neurobiology

Severe Life Stress and Oxidative Stress in the Brain: From Animal Models to Human Pathology

(2012) Stefania Schiavone et al.   ANTIOXIDANTS & REDOX SIGNALING

Beta adrenergic blockade decreases the immunomodulatory effects of social disruption stress

(2012) M.L. Hanke et al.   BRAIN BEHAVIOR AND IMMUNITY

Learning, memory, and glial cell changes following recovery from chronic unpredictable stress

(2012) Yanqing Bian et al.   BRAIN RESEARCH BULLETIN

Chronic Stress Induced Remodeling of the Prefrontal Cortex: Structural Re-Organization of Microglia and the Inhibitory Effect of Minocycline

(2012) M. Hinwood et al.   CEREBRAL CORTEX

Long-Range Ca2+ Waves Transmit Brain-Damage Signals to Microglia

(2012) Dirk Sieger et al.   DEVELOPMENTAL CELL

Beta-adrenergic receptor activation primes microglia cytokine production

(2012) John D. Johnson et al.   JOURNAL OF NEUROIMMUNOLOGY

Microglia Sculpt Postnatal Neural Circuits in an Activity and Complement-Dependent Manner

(2012) Dorothy P. Schafer et al.   NEURON

Glucocorticoid Receptor and FKBP5 Expression Is Altered Following Exposure to Chronic Stress: Modulation by Antidepressant Treatment

(2012) Gianluigi Guidotti et al.   NEUROPSYCHOPHARMACOLOGY

Peripheral innate immune challenge exaggerated microglia activation, increased the number of inflammatory CNS macrophages, and prolonged social withdrawal in socially defeated mice

(2012) Eric S. Wohleb et al.   PSYCHONEUROENDOCRINOLOGY

Stress-induced redistribution of immune cells—From barracks to boulevards to battlefields: A tale of three hormones – Curt Richter Award Winner

(2012) Firdaus S. Dhabhar et al.   PSYCHONEUROENDOCRINOLOGY

Coordinating genome expression with cell size

(2012) Samuel Marguerat et al.   TRENDS IN GENETICS

Signaling in Innate Immunity and Inflammation

(2012) K. Newton et al.   Cold Spring Harbor Perspectives in Biology

Dexamethasone inhibits the Nox-dependent ROS production via suppression of MKP-1-dependent MAPK pathways in activated microglia

(2011) Yingqian Huo et al.   BMC NEUROSCIENCE

Glucocorticoids mediate stress-induced priming of microglial pro-inflammatory responses

(2011) Matthew G. Frank et al.   BRAIN BEHAVIOR AND IMMUNITY

Evidence that Microglia Mediate the Neurobiological Effects of Chronic Psychological Stress on the Medial Prefrontal Cortex

(2011) M. Hinwood et al.   CEREBRAL CORTEX

Cytokines and brain excitability

(2011) Michael A. Galic et al.   FRONTIERS IN NEUROENDOCRINOLOGY

Biochemical Regulation of Sleep and Sleep Biomarkers

(2011) James M. Clinton et al.   Journal of Clinical Sleep Medicine

Chronic Stress Exacerbates Tau Pathology, Neurodegeneration, and Cognitive Performance through a Corticotropin-Releasing Factor Receptor-Dependent Mechanism in a Transgenic Mouse Model of Tauopathy

(2011) J. C. Carroll et al.   JOURNAL OF NEUROSCIENCE

 -Adrenergic Receptor Antagonism Prevents Anxiety-Like Behavior and Microglial Reactivity Induced by Repeated Social Defeat

(2011) E. S. Wohleb et al.   JOURNAL OF NEUROSCIENCE

The stressed synapse: the impact of stress and glucocorticoids on glutamate transmission

(2011) Maurizio Popoli et al.   NATURE REVIEWS NEUROSCIENCE

Psychoneuroimmunology Meets Neuropsychopharmacology: Translational Implications of the Impact of Inflammation on Behavior

(2011) Ebrahim Haroon et al.   NEUROPSYCHOPHARMACOLOGY

Immune system to brain signaling: Neuropsychopharmacological implications

(2011) Lucile Capuron et al.   PHARMACOLOGY & THERAPEUTICS

Microglial Morphology and Dynamic Behavior Is Regulated by Ionotropic Glutamatergic and GABAergic Neurotransmission

(2011) Aurora M. Fontainhas et al.   PLoS One

Microglial glucocorticoid receptors play a pivotal role in regulating dopaminergic neurodegeneration in parkinsonism

(2011) F. Ros-Bernal et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Synaptic Pruning by Microglia Is Necessary for Normal Brain Development

(2011) R. C. Paolicelli et al.   SCIENCE

Chronic stress alters the density and morphology of microglia in a subset of stress-responsive brain regions

(2010) Ross J. Tynan et al.   BRAIN BEHAVIOR AND IMMUNITY

Immune modulation of learning, memory, neural plasticity and neurogenesis

(2010) Raz Yirmiya et al.   BRAIN BEHAVIOR AND IMMUNITY

A Coordinated Global Control over Cellular Transcription

(2010) Jacob Zhurinsky et al.   CURRENT BIOLOGY

Gene Regulation: Global Transcription Rates Scale with Size

(2010) Huzefa Dungrawala et al.   CURRENT BIOLOGY

Interleukin 18 in the CNS

(2010) Silvia Alboni et al.   Journal of Neuroinflammation

Locus ceruleus controls Alzheimer's disease pathology by modulating microglial functions through norepinephrine

(2010) M. T. Heneka et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Sex- and brain region-specific acceleration of β-amyloidogenesis following behavioral stress in a mouse model of Alzheimer's disease

(2010) Latha Devi et al.   Molecular Brain

Microglial Interactions with Synapses Are Modulated by Visual Experience

(2010) Marie-Ève Tremblay et al.   PLOS BIOLOGY

Diurnal expression of functional and clock-related genes throughout the rat HPA axis: system-wide shifts in response to a restricted feeding schedule

(2009) Milena Girotti et al.   AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM

Involvement of NOX2 in the Development of Behavioral and Pathologic Alterations in Isolated Rats

(2009) Stefania Schiavone et al.   BIOLOGICAL PSYCHIATRY

Inflammation and Its Discontents: The Role of Cytokines in the Pathophysiology of Major Depression

(2009) Andrew H. Miller et al.   BIOLOGICAL PSYCHIATRY

Epidemiologic heterogeneity of common mood and anxiety disorders over the lifecourse in the general population: a systematic review

(2009) Arijit Nandi et al.   BMC Psychiatry

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(2009) Matthew G. Frank et al.   BRAIN BEHAVIOR AND IMMUNITY

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(2009) Guo Jun Liu et al.   EUROPEAN JOURNAL OF NEUROSCIENCE

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(2009) Francis Rodriguez Bambico et al.   EUROPEAN NEUROPSYCHOPHARMACOLOGY

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(2009) George P. Chrousos   Nature Reviews Endocrinology

The role of FKBP5, a co-chaperone of the glucocorticoid receptor in the pathogenesis and therapy of affective and anxiety disorders

(2009) Elisabeth B. Binder   PSYCHONEUROENDOCRINOLOGY

Chronic psychosocial stress at work and risk of depression: evidence from prospective studies

(2008) Johannes Siegrist   EUROPEAN ARCHIVES OF PSYCHIATRY AND CLINICAL NEUROSCIENCE

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(2008) Amanda Sierra et al.   GLIA

Glutathione: a novel treatment target in psychiatry

(2008) Michael Berk et al.   TRENDS IN PHARMACOLOGICAL SCIENCES

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From inflammation to sickness and depression: when the immune system subjugates the brain

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