Neuronal impairment following chronic Toxoplasma gondii infection is aggravated by intestinal nematode challenge in an IFN-γ-dependent manner

p75NTR regulates brain mononuclear cell function and neuronal structure in Toxoplasma infection-induced neuroinflammation

(2019) Henning Peter Düsedau et al.   GLIA

Toxoplasma-Induced Hypermigration of Primary Cortical Microglia Implicates GABAergic Signaling

(2019) Amol K. Bhandage et al.   Frontiers in Cellular and Infection Microbiology

Priming of microglia with IFN-γ slows neuronal gamma oscillations in situ

(2019) Thuy-Truc Ta et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Large-scale study of Toxoplasma and Cytomegalovirus shows an association between infection and serious psychiatric disorders

(2019) Kristoffer Sølvsten Burgdorf et al.   BRAIN BEHAVIOR AND IMMUNITY

The Microglial Innate Immune Receptor TREM2 Is Required for Synapse Elimination and Normal Brain Connectivity

(2018) Fabia Filipello et al.   IMMUNITY

Group 1 innate lymphoid cells in Toxoplasma gondii infection

(2018) I. R. Dunay et al.   PARASITE IMMUNOLOGY

The Untapped Pharmacopeic Potential of Helminths

(2018) Janina Kahl et al.   TRENDS IN PARASITOLOGY

Hookworm Secreted Extracellular Vesicles Interact With Host Cells and Prevent Inducible Colitis in Mice

(2018) Ramon M. Eichenberger et al.   Frontiers in Immunology

Treatment of Toxoplasmosis: Historical Perspective, Animal Models, and Current Clinical Practice

(2018) Ildiko Rita Dunay et al.   CLINICAL MICROBIOLOGY REVIEWS

Chronic Toxoplasma infection is associated with distinct alterations in the synaptic protein composition

(2018) Daniel Lang et al.   Journal of Neuroinflammation

Modulation of Host Immunity by Helminths: The Expanding Repertoire of Parasite Effector Molecules

(2018) Rick M. Maizels et al.   IMMUNITY

Immune cells and CNS physiology: Microglia and beyond

(2018) Geoffrey T. Norris et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Safety and efficacy of helminth treatment in relapsing-remitting multiple sclerosis: Results of the HINT 2 clinical trial

(2017) John Fleming et al.   Multiple Sclerosis Journal

Brains and Brawn: Toxoplasma Infections of the Central Nervous System and Skeletal Muscle

(2017) Elizabeth A. Wohlfert et al.   TRENDS IN PARASITOLOGY

Helminth-induced Ly6Chi monocyte-derived alternatively activated macrophages suppress experimental autoimmune encephalomyelitis

(2017) Cesar Terrazas et al.   Scientific Reports

Behavior of Neutrophil Granulocytes during Toxoplasma gondii Infection in the Central Nervous System

(2017) Aindrila Biswas et al.   Frontiers in Cellular and Infection Microbiology

Toxoplasma Co-infection Prevents Th2 Differentiation and Leads to a Helminth-Specific Th1 Response

(2017) Norus Ahmed et al.   Frontiers in Cellular and Infection Microbiology

Safety and efficacy of helminth treatment in relapsing-remitting multiple sclerosis: Results of the HINT 2 clinical trial

(2017) John Fleming et al.   Multiple Sclerosis Journal

Helminth Immunomodulation in Autoimmune Disease

(2017) Taylor B. Smallwood et al.   Frontiers in Immunology

Toxoplasma Modulates Signature Pathways of Human Epilepsy, Neurodegeneration & Cancer

(2017) Huân M. Ngô et al.   Scientific Reports

Toxoplasma gondii Infection in Mice Impairs Long-Term Fear Memory Consolidation through Dysfunction of the Cortex and Amygdala

(2016) Fumiaki Ihara et al.   INFECTION AND IMMUNITY

Cutting Edge: Helminth Coinfection Blocks Effector Differentiation of CD8 T Cells through Alternate Host Th2- and IL-10–Mediated Responses

(2016) Andrew Marple et al.   JOURNAL OF IMMUNOLOGY

Role of the IL-1 Pathway in Dopaminergic Neurodegeneration and Decreased Voluntary Movement

(2016) Andrea Stojakovic et al.   MOLECULAR NEUROBIOLOGY

Unexpected role of interferon-γ in regulating neuronal connectivity and social behaviour

(2016) Anthony J. Filiano et al.   NATURE

PD-1 immune checkpoint blockade reduces pathology and improves memory in mouse models of Alzheimer's disease

(2016) Kuti Baruch et al.   NATURE MEDICINE

Molecular mechanism linking BDNF/TrkB signaling with the NMDA receptor in memory: the role of Girdin in the CNS

(2016) Norimichi Itoh et al.   REVIEWS IN THE NEUROSCIENCES

GLT-1-Dependent Disruption of CNS Glutamate Homeostasis and Neuronal Function by the Protozoan Parasite Toxoplasma gondii

(2016) Clément N. David et al.   PLoS Pathogens

Chronic Toxoplasma gondii infection enhances β-amyloid phagocytosis and clearance by recruited monocytes

(2016) Luisa Möhle et al.   Acta Neuropathologica Communications

Human helminth therapy to treat inflammatory disorders- where do we stand?

(2015) Helena Helmby   BMC IMMUNOLOGY

Immediate rather than delayed memory impairment in older adults with latent toxoplasmosis

(2015) Angelico Mendy et al.   BRAIN BEHAVIOR AND IMMUNITY

Neuroinflammatory TNFα Impairs Memory via Astrocyte Signaling

(2015) Samia Habbas et al.   CELL

Cognitive deterioration among bipolar disorder patients infected by Toxoplasma gondii is correlated to interleukin 6 levels

(2015) Nora Hamdani et al.   JOURNAL OF AFFECTIVE DISORDERS

Ly6ChighMonocytes Control Cerebral Toxoplasmosis

(2015) Aindrila Biswas et al.   JOURNAL OF IMMUNOLOGY

A Novel Regulatory Macrophage Induced by a Helminth Molecule Instructs IL-10 in CD4+T Cells and Protects against Mucosal Inflammation

(2015) Thomas Ziegler et al.   JOURNAL OF IMMUNOLOGY

Long-Term Relationships: the Complicated Interplay between the Host and the Developmental Stages of Toxoplasma gondii during Acute and Chronic Infections

(2015) Kelly J. Pittman et al.   MICROBIOLOGY AND MOLECULAR BIOLOGY REVIEWS

Persistence ofToxoplasma gondiiin the central nervous system: a fine-tuned balance between the parasite, the brain and the immune system

(2015) N. Blanchard et al.   PARASITE IMMUNOLOGY

Toxoplasma gondii-induced neuronal alterations

(2015) A. Parlog et al.   PARASITE IMMUNOLOGY

Toxoplasma gondii Infections Alter GABAergic Synapses and Signaling in the Central Nervous System

(2015) Justin M. Brooks et al.   mBio

IFNγ and IL-12 Restrict Th2 Responses during Helminth/Plasmodium Co-Infection and Promote IFNγ from Th2 Cells

(2015) Stephanie M. Coomes et al.   PLoS Pathogens

Therapeutic potential of larval excretory/secretory proteins of the pig whipwormTrichuris suisin allergic disease

(2014) F. Ebner et al.   ALLERGY

Differentiation of Type 1 ILCs from a Common Progenitor to All Helper-like Innate Lymphoid Cell Lineages

(2014) Christoph S.N. Klose et al.   CELL

Chronic murine toxoplasmosis is defined by subtle changes in neuronal connectivity

(2014) A. Parlog et al.   Disease Models & Mechanisms

Commentary on Myers et al.: Growing role of the innate immunity receptor CD36 in central nervous system diseases

(2014) Lidia Garcia-Bonilla et al.   EXPERIMENTAL NEUROLOGY

Therapeutic uses of anti- 4-integrin (anti-VLA-4) antibodies in multiple sclerosis

(2014) N. Schwab et al.   INTERNATIONAL IMMUNOLOGY

A Helminth Immunomodulator Reduces Allergic and Inflammatory Responses by Induction of IL-10-Producing Macrophages

(2014) C. Schnoeller et al.   JOURNAL OF IMMUNOLOGY

Altered microglial response to Aβ plaques in APPPS1-21 mice heterozygous for TREM2

(2014) Jason D Ulrich et al.   Molecular Neurodegeneration

A Transgenic Probiotic Secreting a Parasite Immunomodulator for Site-Directed Treatment of Gut Inflammation

(2014) Rose A Whelan et al.   MOLECULAR THERAPY

The impact of Toll-like-receptor-9 on intestinal microbiota composition and extra-intestinal sequelae in experimental Toxoplasma gondii induced ileitis

(2014) Stefan Bereswill et al.   Gut Pathogens

Lessons from helminth infections: ES-62 highlights new interventional approaches in rheumatoid arthritis

(2013) M. A. Pineda et al.   CLINICAL AND EXPERIMENTAL IMMUNOLOGY

The resolution of neuroinflammation in neurodegeneration: leukocyte recruitment via the choroid plexus

(2013) Michal Schwartz et al.   EMBO JOURNAL

Immunomodulation by helminth parasites: Defining mechanisms and mediators

(2013) Henry J. McSorley et al.   INTERNATIONAL JOURNAL FOR PARASITOLOGY

BDNF and memory processing

(2013) Pedro Bekinschtein et al.   NEUROPHARMACOLOGY

Location of the CD8 T Cell Epitope within the Antigenic Precursor Determines Immunogenicity and Protection against the Toxoplasma gondii Parasite

(2013) Virginie Feliu et al.   PLoS Pathogens

Translatability of helminth therapy in inflammatory bowel diseases

(2012) Joel V. Weinstock et al.   INTERNATIONAL JOURNAL FOR PARASITOLOGY

Immunologic Privilege in the Central Nervous System and the Blood–Brain Barrier

(2012) Leslie L Muldoon et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

Neuroinflammation and Synaptic Loss

(2012) Jagadeesh S. Rao et al.   NEUROCHEMICAL RESEARCH

Toxoplasma gondii and Other Risk Factors for Schizophrenia: An Update

(2012) E. F. Torrey et al.   SCHIZOPHRENIA BULLETIN

Immunity to the model intestinal helminth parasite Heligmosomoides polygyrus

(2012) Lisa A. Reynolds et al.   Seminars in Immunopathology

Toxoplasma Co-opts Host Cells It Does Not Invade

(2012) Anita A. Koshy et al.   PLoS Pathogens

Macrophages as a Battleground for Toxoplasma Pathogenesis

(2011) Peter J. Murray   Cell Host & Microbe

Probiotic helminth administration in relapsing–remitting multiple sclerosis: a phase 1 study

(2011) JO Fleming et al.   Multiple Sclerosis Journal

Toxoplasma gondii effectors are master regulators of the inflammatory response

(2011) Mariane B. Melo et al.   TRENDS IN PARASITOLOGY

A Helminth Immunomodulator Exploits Host Signaling Events to Regulate Cytokine Production in Macrophages

(2011) Christian Klotz et al.   PLoS Pathogens

Could Toxoplasma gondii Have any Role in Alzheimer Disease?

(2010) Ozge Yilmaz Kusbeci et al.   ALZHEIMER DISEASE & ASSOCIATED DISORDERS

Immune modulation of learning, memory, neural plasticity and neurogenesis

(2010) Raz Yirmiya et al.   BRAIN BEHAVIOR AND IMMUNITY

Regulation of learning and memory by meningeal immunity: a key role for IL-4

(2010) Noël C. Derecki et al.   JOURNAL OF EXPERIMENTAL MEDICINE

The probable relation between Toxoplasma gondii and Parkinson's disease

(2010) Ozlem Miman et al.   NEUROSCIENCE LETTERS

The relation between inflammation and neurodegeneration in multiple sclerosis brains

(2009) Josa M. Frischer et al.   BRAIN

Toxoplasmosis: A history of clinical observations

(2009) Louis M. Weiss et al.   INTERNATIONAL JOURNAL FOR PARASITOLOGY

Inflammation in ALS and SMA: Sorting out the good from the evil

(2009) Dimitra Papadimitriou et al.   NEUROBIOLOGY OF DISEASE

Functional Analysis of Effector and Regulatory T Cells in a Parasitic Nematode Infection

(2008) S. Rausch et al.   INFECTION AND IMMUNITY

Coinfection with Heligmosomoides polygyrus Fails To Establish CD8+ T-Cell Immunity against Toxoplasma gondii

(2008) I. A. Khan et al.   INFECTION AND IMMUNITY

Neurological and behavioral abnormalities, ventricular dilatation, altered cellular functions, inflammation, and neuronal injury in brains of mice due to common, persistent, parasitic infection

(2008) Gretchen Hermes et al.   Journal of Neuroinflammation

Microglial Dysfunction and Defective  -Amyloid Clearance Pathways in Aging Alzheimer's Disease Mice

(2008) S. E. Hickman et al.   JOURNAL OF NEUROSCIENCE