The roles of inducible chromatin and transcriptional memory in cellular defense system responses to redox-active pollutants

One Ring to Rule them All? Structural and Functional Diversity in the Nuclear Pore Complex

(2021) Javier Fernandez-Martinez et al.   TRENDS IN BIOCHEMICAL SCIENCES

Selective modulation by PARP-1 of HIF-1α-recruitment to chromatin during hypoxia is required for tumor adaptation to hypoxic conditions

(2021) Juan Manuel Martí et al.   Redox Biology

The Redox Theory of Development

(2020) Jason M. Hansen et al.   ANTIOXIDANTS & REDOX SIGNALING

Genome-wide meta-analysis associates GPSM1 with type 2 diabetes, a plausible gene involved in skeletal muscle function

(2020) Qiuju Ding et al.   JOURNAL OF HUMAN GENETICS

Astrocyte Unfolded Protein Response Induces a Specific Reactivity State that Causes Non-Cell-Autonomous Neuronal Degeneration

(2020) Heather L. Smith et al.   NEURON

The exposome and health: Where chemistry meets biology

(2020) Roel Vermeulen et al.   SCIENCE

Acetate supplementation restores chromatin accessibility and promotes tumor cell differentiation under hypoxia

(2020) Yang Li et al.   Cell Death & Disease

Chromatin replication and epigenetic cell memory

(2020) Kathleen R. Stewart-Morgan et al.   NATURE CELL BIOLOGY

Uncoupling histone H3K4 trimethylation from developmental gene expression via an equilibrium of COMPASS, Polycomb and DNA methylation

(2020) Delphine Douillet et al.   NATURE GENETICS

Redox toxicology of environmental chemicals causing oxidative stress

(2020) Fuli Zheng et al.   Redox Biology

Mode of action-based risk assessment of genotoxic carcinogens

(2020) Andrea Hartwig et al.   ARCHIVES OF TOXICOLOGY

Histone H3.3 phosphorylation amplifies stimulation-induced transcription

(2020) Anja Armache et al.   NATURE

ATM-associated signalling triggers the unfolded protein response and cell death in response to stress

(2020) Yuka Hotokezaka et al.   Communications Biology

Structural basis of nucleosome dynamics modulation by histone variants H2A.B and H2A.Z.2.2

(2020) Min Zhou et al.   EMBO JOURNAL

TET is targeted for proteasomal degradation by the PHD-pVHL pathway to reduce DNA hydroxymethylation

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Loss of SWI/SNF Chromatin Remodeling Alters NRF2 Signaling in Non–Small Cell Lung Carcinoma

(2020) Shujie Song et al.   MOLECULAR CANCER RESEARCH

Inducible expression of heat shock protein 20 protects airway epithelial cells against oxidative injury involving the Nrf2-NQO-1 pathway

(2020) Aihua Bao et al.   Cell and Bioscience

General anesthesia activates the mitochondrial unfolded protein response and induces age-dependent, long-lasting changes in mitochondrial function in the developing brain

(2020) Yulim Lee et al.   NEUROTOXICOLOGY

Redox regulation by NRF2 in aging and disease

(2019) Cody J. Schmidlin et al.   FREE RADICAL BIOLOGY AND MEDICINE

Heat Shock Factor 1 Drives Intergenic Association of Its Target Gene Loci upon Heat Shock

(2019) Surabhi Chowdhary et al.   Cell Reports

Structural insight into nucleosome transcription by RNA polymerase II with elongation factors

(2019) Haruhiko Ehara et al.   SCIENCE

Nascent-protein ubiquitination is required for heat shock–induced gene downregulation in human cells

(2019) Fernando Aprile-Garcia et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

P-TEFb Activation by RBM7 Shapes a Pro-survival Transcriptional Response to Genotoxic Stress

(2019) Andrii Bugai et al.   MOLECULAR CELL

Extensive Recovery of Embryonic Enhancer and Gene Memory Stored in Hypomethylated Enhancer DNA

(2019) Unmesh Jadhav et al.   MOLECULAR CELL

The effects of bisphenol A, benzyl butyl phthalate, and di(2-ethylhexyl) phthalate on estrogen receptor alpha in estrogen receptor-positive cells under hypoxia

(2019) Choa Park et al.   ENVIRONMENTAL POLLUTION

Promoter-proximal pausing of RNA polymerase II: a nexus of gene regulation

(2019) Leighton Core et al.   GENES & DEVELOPMENT

Molecular Mechanisms Directing PRC2 Recruitment and H3K27 Methylation

(2019) Anne Laugesen et al.   MOLECULAR CELL

Histone Methylation and Memory of Environmental Stress

(2019) Paola Fabrizio et al.   Cells

A New Portrait of Constitutive Heterochromatin: Lessons from Drosophila melanogaster

(2019) René M. Marsano et al.   TRENDS IN GENETICS

Neonatal Intermittent Hypoxia Induces Lasting Sex-Specific Augmentation of Rat Microglial Cytokine Expression

(2019) Elizabeth A. Kiernan et al.   Frontiers in Immunology

Sensitivity of transcription factors to DNA methylation

(2019) Éléa Héberlé et al.   Essays in Biochemistry

Differential and overlapping targets of the transcriptional regulators NRF1, NRF2, and NRF3 in human cells

(2019) Pengfei Liu et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

New insights into transcriptional reprogramming during cellular stress

(2019) Samu V. Himanen et al.   JOURNAL OF CELL SCIENCE

Cadmium exposure triggers mitochondrial dysfunction and oxidative stress in chicken (Gallus gallus) kidney via mitochondrial UPR inhibition and Nrf2-mediated antioxidant defense activation

(2019) Jing Ge et al.   SCIENCE OF THE TOTAL ENVIRONMENT

Fate-mapping post-hypoxic tumor cells reveals a ROS-resistant phenotype that promotes metastasis

(2019) Inês Godet et al.   Nature Communications

Statement on advancing the assessment of chemical mixtures and their risks for human health and the environment

(2019) Elina Drakvik et al.   ENVIRONMENT INTERNATIONAL

Acute Methylmercury Exposure and the Hypoxia-Inducible Factor-1α Signaling Pathway under Normoxic Conditions in the Rat Brain and Astrocytes in Vitro

(2019) Jie Chang et al.   ENVIRONMENTAL HEALTH PERSPECTIVES

Developmental ROS individualizes organismal stress resistance and lifespan

(2019) Daphne Bazopoulou et al.   NATURE

Epigenomic analysis of gastrulation identifies a unique chromatin state for primed pluripotency

(2019) Yunlong Xiang et al.   NATURE GENETICS

Formation of Chromatin Subcompartments by Phase Separation

(2018) Fabian Erdel et al.   BIOPHYSICAL JOURNAL

HIF-dependent and reversible nucleosome disassembly in hypoxia-inducible gene promoters

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Endoplasmic Reticulum Stress signalling - from basic mechanisms to clinical applications

(2018) Aitor Almanza et al.   FEBS Journal

The transcriptional regulator CCCTC-binding factor limits oxidative stress in endothelial cells

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Pioneer transcription factors shape the epigenetic landscape

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UPR mt coordinates immunity to maintain mitochondrial homeostasis and animal fitness

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Capturing the Onset of PRC2-Mediated Repressive Domain Formation

(2018) Ozgur Oksuz et al.   MOLECULAR CELL

Protein-Based Inheritance: Epigenetics beyond the Chromosome

(2018) Zachary H. Harvey et al.   MOLECULAR CELL

The NIEHS TaRGET II Consortium and environmental epigenomics

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Three classes of response elements for human PRC2 and MLL1/2–Trithorax complexes

(2018) Junqing Du et al.   NUCLEIC ACIDS RESEARCH

Cadmium Exposure Inhibits Branching Morphogenesis and Causes Alterations Consistent With HIF-1α Inhibition in Human Primary Breast Organoids

(2018) Sabrina A Rocco et al.   TOXICOLOGICAL SCIENCES

p38-MK2 signaling axis regulates RNA metabolism after UV-light-induced DNA damage

(2018) Marina E. Borisova et al.   Nature Communications

The Memory of Environmental Chemical Exposure in C. elegans Is Dependent on the Jumonji Demethylases jmjd-2 and jmjd-3/utx-1

(2018) Jessica Camacho et al.   Cell Reports

The Exposome: Molecules to Populations

(2018) Megan M. Niedzwiecki et al.   Annual Review of Pharmacology and Toxicology

Modulating NRF2 in Disease: Timing Is Everything

(2018) Matthew Dodson et al.   Annual Review of Pharmacology and Toxicology

Architectural Proteins and Pluripotency Factors Cooperate to Orchestrate the Transcriptional Response of hESCs to Temperature Stress

(2018) Xiaowen Lyu et al.   MOLECULAR CELL

SUMO Safeguards Somatic and Pluripotent Cell Identities by Enforcing Distinct Chromatin States

(2018) Jack-Christophe Cossec et al.   Cell Stem Cell

NRF2 transcriptionally activates the heat shock factor 1 promoter under oxidative stress and affects survival and migration potential of MCF7 cells

(2018) Soumyadip Paul et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

HMGB1 deficiency reduces H2 O2 -induced oxidative damage in human melanocytes via the Nrf2 pathway

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Tailoring of Proteostasis Networks with Heat Shock Factors

(2018) Jenny Joutsen et al.   Cold Spring Harbor Perspectives in Biology

Chromatin-remodeling factor, RSF1, controls p53-mediated transcription in apoptosis upon DNA strand breaks

(2018) Sunwoo Min et al.   Cell Death & Disease

Wild-type p53 regulates OTOP2 transcription through DNA loop alteration of the promoter in colorectal cancer

(2018) Huajun Qu et al.   FEBS Open Bio

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Widespread changes in nucleosome accessibility without changes in nucleosome occupancy during a rapid transcriptional induction

(2017) Britta Mueller et al.   GENES & DEVELOPMENT

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(2017) Jacky Bhagat   JOURNAL OF APPLIED TOXICOLOGY

Kelch-like ECH-associated protein 1 (KEAP1) differentially regulates nuclear factor erythroid-2–related factors 1 and 2 (NRF1 and NRF2)

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Resveratrol: A novel type of topoisomerase II inhibitor

(2017) Joyce H. Lee et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Molecular Mechanisms of IRE1α-ASK1 Pathway Reactions to Unfolded Protein Response in DRN Neurons of Post-Traumatic Stress Disorder Rats

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Methyl CpG level at distal part of heat-shock protein promoter HSP70 exhibits epigenetic memory for heat stress by modulating recruitment of POU2F1-associated nucleosome-remodeling deacetylase (NuRD) complex

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p97 Negatively Regulates NRF2 by Extracting Ubiquitylated NRF2 from the KEAP1-CUL3 E3 Complex

(2017) Shasha Tao et al.   MOLECULAR AND CELLULAR BIOLOGY

Metazoan Nuclear Pores Provide a Scaffold for Poised Genes and Mediate Induced Enhancer-Promoter Contacts

(2017) Pau Pascual-Garcia et al.   MOLECULAR CELL

ATM, ATR, and DNA-PK: The Trinity at the Heart of the DNA Damage Response

(2017) Andrew N. Blackford et al.   MOLECULAR CELL

Phase separation drives heterochromatin domain formation

(2017) Amy R. Strom et al.   NATURE

Competing memories of mitogen and p53 signalling control cell-cycle entry

(2017) Hee Won Yang et al.   NATURE

Oxidative stress rapidly stabilizes promoter-proximal paused Pol II across the human genome

(2017) Kyle A. Nilson et al.   NUCLEIC ACIDS RESEARCH

ATF5 regulates β-cell survival during stress

(2017) Christine A. Juliana et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Comparative analysis reveals genomic features of stress-induced transcriptional readthrough

(2017) Anna Vilborg et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Oxidative DNA damage is epigenetic by regulating gene transcription via base excision repair

(2017) Aaron M. Fleming et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

DNA sequence-dependent epigenetic inheritance of gene silencing and histone H3K9 methylation

(2017) Xiaoyi Wang et al.   SCIENCE

Mitochondrial-epigenetic crosstalk in environmental toxicology

(2017) Caren Weinhouse   TOXICOLOGY

Live-cell p53 single-molecule binding is modulated by C-terminal acetylation and correlates with transcriptional activity

(2017) Alessia Loffreda et al.   Nature Communications

Transcriptional response to stress is pre-wired by promoter and enhancer architecture

(2017) Anniina Vihervaara et al.   Nature Communications

Histone H3 phosphorylation, immediate-early gene expression, and the nucleosomal response: a historical perspective1This article is part of Special Issue entitled Asilomar Chromatin and has undergone the Journal’s usual peer review process.

(2017) Shannon Healy et al.   Biochemistry and Cell Biology

CTCF-mediated chromatin loops enclose inducible gene regulatory domains

(2016) Martin Oti et al.   BMC GENOMICS

Two Conserved Histone Demethylases Regulate Mitochondrial Stress-Induced Longevity

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Mitochondrial Stress Induces Chromatin Reorganization to Promote Longevity and UPR mt

(2016) Ye Tian et al.   CELL

Epigenetics, cellular memory and gene regulation

(2016) Steven Henikoff et al.   CURRENT BIOLOGY

Capture‐C reveals preformed chromatin interactions between HIF‐binding sites and distant promoters

(2016) James L Platt et al.   EMBO REPORTS

Monoubiquitination of Histone H2B Blocks Eviction of Histone Variant H2A.Z from Inducible Enhancers

(2016) Gregory Segala et al.   MOLECULAR CELL

Mammalian Heat Shock Response and Mechanisms Underlying Its Genome-wide Transcriptional Regulation

(2016) Dig B. Mahat et al.   MOLECULAR CELL

Chromatin-Bound MDM2 Regulates Serine Metabolism and Redox Homeostasis Independently of p53

(2016) Romain Riscal et al.   MOLECULAR CELL

Reprogramming of the Epigenome by MLL1 Links Early-Life Environmental Exposures to Prostate Cancer Risk

(2016) Quan Wang et al.   MOLECULAR ENDOCRINOLOGY

Tumour hypoxia causes DNA hypermethylation by reducing TET activity

(2016) Bernard Thienpont et al.   NATURE

Enhancers as non-coding RNA transcription units: recent insights and future perspectives

(2016) Wenbo Li et al.   NATURE REVIEWS GENETICS

High-Resolution 4C Reveals Rapid p53-Dependent Chromatin Reorganization of the CDKN1A Locus in Response to Stress

(2016) Jean-François Millau et al.   PLoS One

Spatial organization of chromatin domains and compartments in single chromosomes

(2016) Siyuan Wang et al.   SCIENCE

Oxidative stress signaling to chromatin in health and disease

(2016) Sarah Kreuz et al.   Epigenomics

Histone H4 lysine 20 acetylation is associated with gene repression in human cells

(2016) Jun-Ya Kaimori et al.   Scientific Reports

The TIP60 Complex Is a Conserved Coactivator of HIF1A

(2016) Joel I. Perez-Perri et al.   Cell Reports

A Chromatin-Focused siRNA Screen for Regulators of p53-Dependent Transcription

(2016) Morgan A. Sammons et al.   G3-Genes Genomes Genetics

Histone H2B ubiquitylation represses gametogenesis by opposing RSC-dependent chromatin remodeling at the ste11 master regulator locus

(2016) Philippe Materne et al.   eLife

Set1/COMPASS and Mediator are repurposed to promote epigenetic transcriptional memory

(2016) Agustina D'Urso et al.   eLife

REST is a hypoxia-responsive transcriptional repressor

(2016) Miguel A. S. Cavadas et al.   Scientific Reports

Dioxin induces Ahr-dependent robust DNA demethylation of the Cyp1a1 promoter via Tdg in the mouse liver

(2016) Hesbon Z. Amenya et al.   Scientific Reports

Nrf2 regulates PU.1 expression and activity in the alveolar macrophage

(2015) Bashar S. Staitieh et al.   AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY

Non-CG Methylation in the Human Genome

(2015) Yupeng He et al.   Annual Review of Genomics and Human Genetics

Effects of Olive Metabolites on DNA Cleavage Mediated by Human Type II Topoisomerases

(2015) Kendra R. Vann et al.   BIOCHEMISTRY

A hit-and-run heat shock factor governs sustained histone methylation and transcriptional stress memory

(2015) J. La mke et al.   EMBO JOURNAL

Oxidative stress alters global histone modification and DNA methylation

(2015) Yingmei Niu et al.   FREE RADICAL BIOLOGY AND MEDICINE

DNA Methylation, Its Mediators and Genome Integrity

(2015) Huan Meng et al.   International Journal of Biological Sciences

Fumarate and Succinate Regulate Expression of Hypoxia-inducible Genes via TET Enzymes

(2015) Tuomas Laukka et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The unpredictability of prolonged activation of stress response pathways

(2015) Lilian T. Lamech et al.   JOURNAL OF CELL BIOLOGY

Dynamics of chromatin accessibility and epigenetic state in response to UV damage

(2015) S. Schick et al.   JOURNAL OF CELL SCIENCE

Widespread Inducible Transcription Downstream of Human Genes

(2015) Anna Vilborg et al.   MOLECULAR CELL

Widespread Rearrangement of 3D Chromatin Organization Underlies Polycomb-Mediated Stress-Induced Silencing

(2015) Li Li et al.   MOLECULAR CELL

Minireview: Tipping the Balance: Ligand-Independent Activation of Steroid Receptors

(2015) Marcela A. Bennesch et al.   MOLECULAR ENDOCRINOLOGY

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(2015) Ana Pombo et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Histone exchange, chromatin structure and the regulation of transcription

(2015) Swaminathan Venkatesh et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Destruction of a distal hypoxia response element abolishestrans-activation of thePAG1gene mediated by HIF-independent chromatin looping

(2015) Alexandra Schörg et al.   NUCLEIC ACIDS RESEARCH

H3K4 monomethylation dictates nucleosome dynamics and chromatin remodeling at stress-responsive genes

(2015) Mariona Nadal-Ribelles et al.   NUCLEIC ACIDS RESEARCH

The CSB chromatin remodeler and CTCF architectural protein cooperate in response to oxidative stress

(2015) Robert J. Lake et al.   NUCLEIC ACIDS RESEARCH

3-Deoxyglucosone: A Potential Glycating Agent Accountable for Structural Alteration in H3 Histone Protein through Generation of Different AGEs

(2015) Jalaluddin M. Ashraf et al.   PLoS One

Proteotoxic stress reprograms the chromatin landscape of SUMO modification

(2015) Anne Seifert et al.   Science Signaling

DOT1L Activity Promotes Proliferation and Protects Cortical Neural Stem Cells from Activation of ATF4-DDIT3-Mediated ER Stress In Vitro

(2015) Deborah Roidl et al.   STEM CELLS

Mismatch repair proteins recruit DNA methyltransferase 1 to sites of oxidative DNA damage

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Proteotoxic stress reprograms the chromatin landscape of SUMO modification

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Cellular memory of hypoxia elicits neuroblastoma metastasis and enables invasion by non-aggressive neighbouring cells

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Glycation of H1 Histone by 3-Deoxyglucosone: Effects on Protein Structure and Generation of Different Advanced Glycation End Products

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Enhancer Activation Requires trans-Recruitment of a Mega Transcription Factor Complex

(2014) Zhijie Liu et al.   CELL

A 3D Map of the Human Genome at Kilobase Resolution Reveals Principles of Chromatin Looping

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Regulatory crosstalk and interference between the xenobiotic and hypoxia sensing pathways at the AhR-ARNT-HIF1α signaling node

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Predicting the carcinogenicity of chemicals with alternative approaches: recent advances

(2014) Romualdo Benigni   Expert Opinion on Drug Metabolism & Toxicology

Cotranscriptional histone H2B monoubiquitylation is tightly coupled with RNA polymerase II elongation rate

(2014) Gilad Fuchs et al.   GENOME RESEARCH

Methylglyoxal mediated conformational changes in histone H2A—generation of carboxyethylated advanced glycation end products

(2014) Abdul Rouf Mir et al.   INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES

Physicochemical analysis of structural alteration and advanced glycation end products generation during glycation of H2A histone by 3-deoxyglucosone

(2014) Jalaluddin M. Ashraf et al.   IUBMB LIFE

Genomic Heat Shock Element Sequences Drive Cooperative Human Heat Shock Factor 1 DNA Binding and Selectivity

(2014) Alex M. Jaeger et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

8-Oxoguanine DNA Glycosylase-1 Augments Proinflammatory Gene Expression by Facilitating the Recruitment of Site-Specific Transcription Factors

(2014) X. Ba et al.   JOURNAL OF IMMUNOLOGY

Nucleosomes Are Context-Specific, H2A.Z-Modulated Barriers to RNA Polymerase

(2014) Christopher M. Weber et al.   MOLECULAR CELL

Enhancer loops appear stable during development and are associated with paused polymerase

(2014) Yad Ghavi-Helm et al.   NATURE

Ash2L enables P53-dependent apoptosis by favoring stable transcription pre-initiation complex formation on its pro-apoptotic target promoters

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A Novel Pathway Links Oxidative Stress to Loss of Insulin Growth Factor-2 (IGF2) Imprinting through NF-κB Activation

(2014) Bing Yang et al.   PLoS One

Poly(ADP-Ribosyl)ation Is Required to Modulate Chromatin Changes at c-MYC Promoter during Emergence from Quiescence

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The Caenorhabditis elegans HP1 family protein HPL-2 maintains ER homeostasis through the UPR and hormesis

(2014) L. Kozlowski et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Smoking and Preterm Birth

(2014) Rachel Ion et al.   Reproductive Sciences

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(2014) K. Ragunathan et al.   SCIENCE

HSF-1-mediated cytoskeletal integrity determines thermotolerance and life span

(2014) N. A. Baird et al.   SCIENCE

H3K27me and PRC2 transmit a memory of repression across generations and during development

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mTOR- and HIF-1 -mediated aerobic glycolysis as metabolic basis for trained immunity

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PCB 126 toxicity is modulated by cross-talk between caveolae and Nrf2 signaling

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Silencing of the DNA Mismatch Repair Gene MLH1 Induced by Hypoxic Stress in a Pathway Dependent on the Histone Demethylase LSD1

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Bromodomain Protein BRD4 Is Required for Estrogen Receptor-Dependent Enhancer Activation and Gene Transcription

(2014) Sankari Nagarajan et al.   Cell Reports

TET1-Mediated Hydroxymethylation Facilitates Hypoxic Gene Induction in Neuroblastoma

(2014) Christopher J. Mariani et al.   Cell Reports

Redox biology: Interface of the exposome with the proteome, epigenome and genome

(2014) Young-Mi Go et al.   Redox Biology

De Novo Mutations in the Genome Organizer CTCF Cause Intellectual Disability

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Studies on peroxynitrite-modified H1 histone: Implications in systemic lupus erythematosus

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SWR-C and INO80 Chromatin Remodelers Recognize Nucleosome-free Regions Near +1 Nucleosomes

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HIF1A Employs CDK8-Mediator to Stimulate RNAPII Elongation in Response to Hypoxia

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Extensive regulation of the non-coding transcriptome by hypoxia: role of HIF in releasing paused RNApol2

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Cigarette Smoke Component Acrolein Modulates Chromatin Assembly by Inhibiting Histone Acetylation

(2013) Danqi Chen et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

BRG1 and BRM Chromatin-Remodeling Complexes Regulate the Hypoxia Response by Acting as Coactivators for a Subset of Hypoxia-Inducible Transcription Factor Target Genes

(2013) J. A. Sena et al.   MOLECULAR AND CELLULAR BIOLOGY

A high-resolution map of the three-dimensional chromatin interactome in human cells

(2013) Fulai Jin et al.   NATURE

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(2013) Gabriel E Zentner et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

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(2013) Atsushi Maruyama et al.   NUCLEIC ACIDS RESEARCH

A Dual Role for SAGA-Associated Factor 29 (SGF29) in ER Stress Survival by Coordination of Both Histone H3 Acetylation and Histone H3 Lysine-4 Trimethylation

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A Histone Acetylation Switch Regulates H2A.Z Deposition by the SWR-C Remodeling Enzyme

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Extensive Promoter-Centered Chromatin Interactions Provide a Topological Basis for Transcription Regulation

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Candida albicans Infection Affords Protection against Reinfection via Functional Reprogramming of Monocytes

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Post-Translational Modification of Human Heat Shock Factors and Their Functions: A Recent Update by Proteomic Approach

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(2012) Karen Adelman et al.   NATURE REVIEWS GENETICS

Functional interplay between p53 acetylation and H1.2 phosphorylation in p53-regulated transcription

(2012) K Kim et al.   ONCOGENE

UPR-Induced Resistance to Etoposide Is Downstream of PERK and Independent of Changes in Topoisomerase IIα Levels

(2012) Melissa J. Mann et al.   PLoS One

Treatment of doxorubicin-resistant MCF7/Dx cells with nitric oxide causes histone glutathionylation and reversal of drug resistance

(2011) Anastasia de Luca et al.   BIOCHEMICAL JOURNAL

High-resolution genome-wide mapping of HIF-binding sites by ChIP-seq

(2011) J. Schodel et al.   BLOOD

Oxidative Damage Targets Complexes Containing DNA Methyltransferases, SIRT1, and Polycomb Members to Promoter CpG Islands

(2011) Heather M. O'Hagan et al.   CANCER CELL

Estrogen-Dependent Gene Transcription in Human Breast Cancer Cells Relies upon Proteasome-Dependent Monoubiquitination of Histone H2B

(2011) T. Prenzel et al.   CANCER RESEARCH

Mechanisms for the Inheritance of Chromatin States

(2011) Danesh Moazed   CELL

Global Regulation of H2A.Z Localization by the INO80 Chromatin-Remodeling Enzyme Is Essential for Genome Integrity

(2011) Manolis Papamichos-Chronakis et al.   CELL

Regulation of chromatin by histone modifications

(2011) Andrew J Bannister et al.   CELL RESEARCH

Chromatin as an oxygen sensor and active player in the hypoxia response

(2011) Andrew Melvin et al.   CELLULAR SIGNALLING

Spreading Chromatin into Chemical Biology

(2011) C. David Allis et al.   CHEMBIOCHEM

Sir2 histone deacetylase prevents programmed cell death caused by sustained activation of the Hog1 stress-activated protein kinase

(2011) Alexandre Vendrell et al.   EMBO REPORTS

Genome-wide function of H2B ubiquitylation in promoter and genic regions

(2011) K. Batta et al.   GENES & DEVELOPMENT

CpG islands and the regulation of transcription

(2011) A. M. Deaton et al.   GENES & DEVELOPMENT

Reciprocally Regulated Chromatin Association of Cockayne Syndrome Protein B and p53 Protein

(2011) Robert J. Lake et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Hypoxia-Induced Epigenetic Regulation and Silencing of the BRCA1 Promoter

(2011) Y. Lu et al.   MOLECULAR AND CELLULAR BIOLOGY

Regulation of Primary Response Genes

(2011) Trent Fowler et al.   MOLECULAR CELL

53BP1 nuclear bodies form around DNA lesions generated by mitotic transmission of chromosomes under replication stress

(2011) Claudia Lukas et al.   NATURE CELL BIOLOGY

Controlling gene expression in response to stress

(2011) Eulàlia de Nadal et al.   NATURE REVIEWS GENETICS

Recognition of enhancer element–specific histone methylation by TIP60 in transcriptional activation

(2011) Kwang Won Jeong et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Regulation of u-PAR gene expression by H2A.Z is modulated by the MEK–ERK/AP-1 pathway

(2011) Santosh Chauhan et al.   NUCLEIC ACIDS RESEARCH

Aberrant Promoter CpG Methylation Is a Mechanism for Impaired PHD3 Expression in a Diverse Set of Malignant Cells

(2011) Trenton L. Place et al.   PLoS One

Stress-Induced PARP Activation Mediates Recruitment of Drosophila Mi-2 to Promote Heat Shock Gene Expression

(2011) Magdalena Murawska et al.   PLoS Genetics

The Redox Basis of Epigenetic Modifications: From Mechanisms to Functional Consequences

(2010) Anthony R. Cyr et al.   ANTIOXIDANTS & REDOX SIGNALING

Mechanisms and functions of p38 MAPK signalling

(2010) Ana Cuadrado et al.   BIOCHEMICAL JOURNAL

Whole genome analysis of p38 SAPK-mediated gene expression upon stress

(2010) Isabel Ferreiro et al.   BMC GENOMICS

Hypoxia Induces Trimethylated H3 Lysine 4 by Inhibition of JARID1A Demethylase

(2010) X. Zhou et al.   CANCER RESEARCH

Ambient Thermometers in Plants: From Physiological Outputs towards Mechanisms of Thermal Sensing

(2010) C. Robertson McClung et al.   CURRENT BIOLOGY

Do chromatin loops provide epigenetic gene expression states?

(2010) Wulan Deng et al.   CURRENT OPINION IN GENETICS & DEVELOPMENT

DNA methylation analysis of the HIF-1α prolyl hydroxylase domain genes PHD1, PHD2, PHD3 and the factor inhibiting HIF gene FIH in invasive breast carcinomas

(2010) Katie T Huang et al.   HISTOPATHOLOGY

Posttranslational modifications in histones underlie heat acclimation-mediated cytoprotective memory

(2010) Anna Tetievsky et al.   JOURNAL OF APPLIED PHYSIOLOGY

The p38 SAPK Is Recruited to Chromatin via Its Interaction with Transcription Factors

(2010) Isabel Ferreiro et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Redox Signaling, Alkylation (Carbonylation) of Conserved Cysteines Inactivates Class I Histone Deacetylases 1, 2, and 3 and Antagonizes Their Transcriptional Repressor Function

(2010) Kelly Doyle et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Dominant Role for Signal Transduction in the Transcriptional Memory of Yeast GAL Genes

(2010) S. Kundu et al.   MOLECULAR AND CELLULAR BIOLOGY

Recruitment Timing and Dynamics of Transcription Factors at the Hsp70 Loci in Living Cells

(2010) Katie L. Zobeck et al.   MOLECULAR CELL

Interaction of a DNA Zip Code with the Nuclear Pore Complex Promotes H2A.Z Incorporation and INO1 Transcriptional Memory

(2010) William H. Light et al.   MOLECULAR CELL

DNA zip codes control an ancient mechanism for gene targeting to the nuclear periphery

(2010) Sara Ahmed et al.   NATURE CELL BIOLOGY

Inducible gene expression: diverse regulatory mechanisms

(2010) Vikki M. Weake et al.   NATURE REVIEWS GENETICS

Promoter chromatin remodeling of immediate-early genes is mediated through H3 phosphorylation at either serine 28 or 10 by the MSK1 multi-protein complex

(2010) Bojan Drobic et al.   NUCLEIC ACIDS RESEARCH

Roles of Coactivators in Hypoxic Induction of the Erythropoietin Gene

(2010) Feng Wang et al.   PLoS One

RNA polymerase complexes cooperate to relieve the nucleosomal barrier and evict histones

(2010) O. I. Kulaeva et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Molecular coupling of DNA methylation and histone methylation

(2010) Hideharu Hashimoto et al.   Epigenomics

Chromatin Landscape Dictates HSF Binding to Target DNA Elements

(2010) Michael J. Guertin et al.   PLoS Genetics

The Biology of Chromatin Remodeling Complexes

(2009) Cedric R. Clapier et al.   Annual Review of Biochemistry

Control of Inducible Gene Expression by Signal-Dependent Transcriptional Elongation

(2009) Diana C. Hargreaves et al.   CELL

A Unifying Model for the Selective Regulation of Inducible Transcription by CpG Islands and Nucleosome Remodeling

(2009) Vladimir R. Ramirez-Carrozzi et al.   CELL

Epigenetics and environmental chemicals

(2009) Andrea Baccarelli et al.   CURRENT OPINION IN PEDIATRICS

Jmjd3 contributes to the control of gene expression in LPS-activated macrophages

(2009) Francesca De Santa et al.   EMBO JOURNAL

Histone H2A.Z is essential for estrogen receptor signaling

(2009) N. Gevry et al.   GENES & DEVELOPMENT

Gene loops function to maintain transcriptional memory through interaction with the nuclear pore complex

(2009) Sue Mei Tan-Wong et al.   GENES & DEVELOPMENT

Physicochemical studies on peroxynitrite-modified H3 histone

(2009) Kiran Dixit et al.   INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES

Lung cancer secreted microvesicles: Underappreciated modulators of microenvironment in expanding tumors

(2009) Marcin Wysoczynski et al.   INTERNATIONAL JOURNAL OF CANCER

Potent Phagocytic Activity with Impaired Antigen Presentation Identifying Lipopolysaccharide-Tolerant Human Monocytes: Demonstration in Isolated Monocytes from Cystic Fibrosis Patients

(2009) Carlos del Fresno et al.   JOURNAL OF IMMUNOLOGY

Regulation of the Histone Demethylase JMJD1A by Hypoxia-Inducible Factor 1  Enhances Hypoxic Gene Expression and Tumor Growth

(2009) A. J. Krieg et al.   MOLECULAR AND CELLULAR BIOLOGY

Chromatin-Specific Remodeling by HMGB1 and Linker Histone H1 Silences Proinflammatory Genes during Endotoxin Tolerance

(2009) M. E. Gazzar et al.   MOLECULAR AND CELLULAR BIOLOGY

The DNA-damage response in human biology and disease

(2009) Stephen P. Jackson et al.   NATURE

H3.3/H2A.Z double variant–containing nucleosomes mark 'nucleosome-free regions' of active promoters and other regulatory regions

(2009) Chunyuan Jin et al.   NATURE GENETICS

Aberrant Epigenetic Silencing Is Triggered by a Transient Reduction in Gene Expression

(2009) Jon A. Oyer et al.   PLoS One

B2 RNA and Alu RNA repress transcription by disrupting contacts between RNA polymerase II and promoter DNA within assembled complexes

(2009) P. Yakovchuk et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Dynamic bookmarking of primary response genes by p300 and RNA polymerase II complexes

(2009) J. S. Byun et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Comprehensive Mapping of Long-Range Interactions Reveals Folding Principles of the Human Genome

(2009) E. Lieberman-Aiden et al.   SCIENCE

Cellular Stress Response Pathway System as a Sentinel Ensemble in Toxicological Screening

(2009) Steven O. Simmons et al.   TOXICOLOGICAL SCIENCES

The versatile role of MSKs in transcriptional regulation

(2009) Linda Vermeulen et al.   TRENDS IN BIOCHEMICAL SCIENCES

Endotoxin tolerance: new mechanisms, molecules and clinical significance

(2009) Subhra K. Biswas et al.   TRENDS IN IMMUNOLOGY

Preferential binding of HIF-1 to transcriptionally active loci determines cell-type specific response to hypoxia

(2009) Xiaobo Xia et al.   GENOME BIOLOGY

Defining the chromatin signature of inducible genes in T cells

(2009) Pek S Lim et al.   GENOME BIOLOGY

Critical Role of the Stress Chaperone GRP78/BiP in Tumor Proliferation, Survival, and Tumor Angiogenesis in Transgene-Induced Mammary Tumor Development

(2008) D. Dong et al.   CANCER RESEARCH

Rapid, Transcription-Independent Loss of Nucleosomes over a Large Chromatin Domain at Hsp70 Loci

(2008) Steven J. Petesch et al.   CELL

Dietary Polyphenols as Topoisomerase II Poisons: B Ring and C Ring Substituents Determine the Mechanism of Enzyme-Mediated DNA Cleavage Enhancement

(2008) Omari J. Bandele et al.   CHEMICAL RESEARCH IN TOXICOLOGY

The histone H2B-specific ubiquitin ligase RNF20/hBRE1 acts as a putative tumor suppressor through selective regulation of gene expression

(2008) E. Shema et al.   GENES & DEVELOPMENT

Global histone acetylation induces functional genomic reorganization at mammalian nuclear pore complexes

(2008) C. R. Brown et al.   GENES & DEVELOPMENT

CBF/NF-Y controls endoplasmic reticulum stress induced transcription through recruitment of both ATF6(N) and TBP

(2008) Rong Luo et al.   JOURNAL OF CELLULAR BIOCHEMISTRY

p53-Targeted LSD1 Functions in Repression of Chromatin Structure and Transcription In Vivo

(2008) W.-W. Tsai et al.   MOLECULAR AND CELLULAR BIOLOGY

Stress-Dependent Dynamics of Global Chromatin Remodeling in Yeast: Dual Role for SWI/SNF in the Heat Shock Stress Response

(2008) S. Shivaswamy et al.   MOLECULAR AND CELLULAR BIOLOGY

Stress-activated Genomic Expression Changes Serve a Preparative Role for Impending Stress in Yeast

(2008) David B. Berry et al.   MOLECULAR BIOLOGY OF THE CELL

Human Alu RNA Is a Modular Transacting Repressor of mRNA Transcription during Heat Shock

(2008) Peter D. Mariner et al.   MOLECULAR CELL

Histone Ubiquitination: Triggering Gene Activity

(2008) Vikki M. Weake et al.   MOLECULAR CELL

H2B Ubiquitylation Plays a Role in Nucleosome Dynamics during Transcription Elongation

(2008) Alastair B. Fleming et al.   MOLECULAR CELL

Activation of the Chaperone Hsp26 Is Controlled by the Rearrangement of Its Thermosensor Domain

(2008) Titus M. Franzmann et al.   MOLECULAR CELL

Exchange of GATA Factors Mediates Transitions in Looped Chromatin Organization at a Developmentally Regulated Gene Locus

(2008) Huie Jing et al.   MOLECULAR CELL

The Putative Cancer Stem Cell Marker USP22 Is a Subunit of the Human SAGA Complex Required for Activated Transcription and Cell-Cycle Progression

(2008) Xiao-Yong Zhang et al.   MOLECULAR CELL

Poised Polymerases: On Your Mark…Get Set…Go!

(2008) David H. Price   MOLECULAR CELL

An internal thermal sensor controlling temperature preference in Drosophila

(2008) Fumika N. Hamada et al.   NATURE

Monoubiquitinated H2B is associated with the transcribed region of highly expressed genes in human cells

(2008) Neri Minsky et al.   NATURE CELL BIOLOGY

PcG Proteins, DNA Methylation, and Gene Repression by Chromatin Looping

(2008) Vijay K Tiwari et al.   PLOS BIOLOGY