Dioxin induces Ahr-dependent robust DNA demethylation of the Cyp1a1 promoter via Tdg in the mouse liver

Oxidative stress triggers cytokinesis failure in hepatocytes upon isolation

(2015) A. M. Tormos et al.   FREE RADICAL RESEARCH

Induction of Tet3-dependent Epigenetic Remodeling by Low-dose Hydralazine Attenuates Progression of Chronic Kidney Disease

(2015) Björn Tampe et al.   EBioMedicine

The Aryl Hydrocarbon Receptor: Multitasking in the Immune System

(2014) Brigitta Stockinger et al.   Annual Review of Immunology

Epigenetic Determinants of CYP1A1 Induction by the Aryl Hydrocarbon Receptor Agonist 3,3',4,4',5-Pentachlorobiphenyl (PCB 126)

(2014) Sabine Vorrink et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Epigenetic mechanisms of importance for drug treatment

(2014) Maxim Ivanov et al.   TRENDS IN PHARMACOLOGICAL SCIENCES

Genome-wide Analysis Reveals TET- and TDG-Dependent 5-Methylcytosine Oxidation Dynamics

(2013) Li Shen et al.   CELL

Hydroquinone Increases 5-Hydroxymethylcytosine Formation through Ten Eleven Translocation 1 (TET1) 5-Methylcytosine Dioxygenase

(2013) Jonathan B. Coulter et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Targeted DNA demethylation and activation of endogenous genes using programmable TALE-TET1 fusion proteins

(2013) Morgan L Maeder et al.   NATURE BIOTECHNOLOGY

PPARγ-induced PARylation promotes local DNA demethylation by production of 5-hydroxymethylcytosine

(2013) Katsunori Fujiki et al.   Nature Communications

The Aryl Hydrocarbon Receptor Complex and the Control of Gene Expression

(2012) Timothy V. Beischlag et al.   CRITICAL REVIEWS IN EUKARYOTIC GENE EXPRESSION

Neonatal activation of the nuclear receptor CAR results in epigenetic memory and permanent change of drug metabolism in mouse liver

(2012) Wei-Dong Chen et al.   HEPATOLOGY

Non-genotoxic carcinogen exposure induces defined changes in the 5-hydroxymethylome

(2012) John P Thomson et al.   GENOME BIOLOGY

Hydroxylation of 5-Methylcytosine by TET1 Promotes Active DNA Demethylation in the Adult Brain

(2011) Junjie U. Guo et al.   CELL

Thymine DNA Glycosylase Can Rapidly Excise 5-Formylcytosine and 5-Carboxylcytosine

(2011) Atanu Maiti et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Phenobarbital Mediates an Epigenetic Switch at the Constitutive Androstane Receptor (CAR) Target Gene Cyp2b10 in the Liver of B6C3F1 Mice

(2011) Harri Lempiäinen et al.   PLoS One

Aryl Hydrocarbon Receptor Ligands of Widely Different Toxic Equivalency Factors Induce Similar Histone Marks in Target Gene Chromatin

(2011) Jerald L. Ovesen et al.   TOXICOLOGICAL SCIENCES

The Implications of DNA Methylation for Toxicology: Toward Toxicomethylomics, the Toxicology of DNA Methylation

(2011) Moshe Szyf   TOXICOLOGICAL SCIENCES

Genome-wide interplay of nuclear receptors with the epigenome

(2010) Joost H.A. Martens et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

The aryl hydrocarbon receptor: Regulation of hematopoiesis and involvement in the progression of blood diseases

(2010) Fanny L. Casado et al.   BLOOD CELLS MOLECULES AND DISEASES

Role of Epigenetic Mechanisms in Differential Regulation of the Dioxin-Inducible Human CYP1A1 and CYP1B1 Genes

(2010) S. R. Beedanagari et al.   MOLECULAR PHARMACOLOGY

Active DNA demethylation: many roads lead to Rome

(2010) Susan C. Wu et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Sensitive enzymatic quantification of 5-hydroxymethylcytosine in genomic DNA

(2010) Aleksandra Szwagierczak et al.   NUCLEIC ACIDS RESEARCH

Comparative Contribution of the Aryl Hydrocarbon Receptor Gene to Perinatal Stage Development and Dioxin-Induced Toxicity Between the Urogenital Complex and Testis in the Mouse1

(2009) Seiichiroh Ohsako et al.   BIOLOGY OF REPRODUCTION

Epigenetic responses to environmental change and their evolutionary implications

(2009) B. M. Turner   PHILOSOPHICAL TRANSACTIONS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES

Conversion of 5-Methylcytosine to 5-Hydroxymethylcytosine in Mammalian DNA by MLL Partner TET1

(2009) M. Tahiliani et al.   SCIENCE