The transcriptional regulator CCCTC-binding factor limits oxidative stress in endothelial cells

Hypoxia induces heart regeneration in adult mice

(2017) Yuji Nakada et al.   NATURE

Cohesin is positioned in mammalian genomes by transcription, CTCF and Wapl

(2017) Georg A. Busslinger et al.   NATURE

CTCF counter-regulates cardiomyocyte development and maturation programs in the embryonic heart

(2017) Melisa Gomez-Velazquez et al.   PLoS Genetics

CTCF-mediated topological boundaries during development foster appropriate gene regulation

(2016) Varun Narendra et al.   GENES & DEVELOPMENT

Efficient attenuation of Friedreich's ataxia (FRDA) cardiomyopathy by modulation of iron homeostasis-human induced pluripotent stem cell (hiPSC) as a drug screening platform for FRDA

(2016) Yee-Ki Lee et al.   INTERNATIONAL JOURNAL OF CARDIOLOGY

'Mitochondrial energy imbalance and lipid peroxidation cause cell death in Friedreich’s ataxia'

(2016) R Abeti et al.   Cell Death & Disease

Disruptions of Topological Chromatin Domains Cause Pathogenic Rewiring of Gene-Enhancer Interactions

(2015) Darío G. Lupiáñez et al.   CELL

The molecular regulation of arteriovenous specification and maintenance

(2015) Jason E. Fish et al.   DEVELOPMENTAL DYNAMICS

The CSB chromatin remodeler and CTCF architectural protein cooperate in response to oxidative stress

(2015) Robert J. Lake et al.   NUCLEIC ACIDS RESEARCH

HTSeq--a Python framework to work with high-throughput sequencing data

(2014) S. Anders et al.   BIOINFORMATICS

Trimmomatic: a flexible trimmer for Illumina sequence data

(2014) Anthony M. Bolger et al.   BIOINFORMATICS

Ezh2-mediated repression of a transcriptional pathway upstream of Mmp9 maintains integrity of the developing vasculature

(2014) P. Delgado-Olguin et al.   DEVELOPMENT

Altered Nucleosome Positioning at the Transcription Start Site and Deficient Transcriptional Initiation in Friedreich Ataxia

(2014) Yogesh K. Chutake et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Functional interplay between MyoD and CTCF in regulating long-range chromatin interactions during differentiation

(2014) C. Battistelli et al.   JOURNAL OF CELL SCIENCE

Vascular development and hemodynamic force in the mouse yolk sac

(2014) Monica D. Garcia et al.   Frontiers in Physiology

Oxidative stress in angiogenesis and vascular disease

(2013) Y.-W. Kim et al.   BLOOD

Cell death and diseases related to oxidative stress:4-hydroxynonenal (HNE) in the balance

(2013) S Dalleau et al.   CELL DEATH AND DIFFERENTIATION

Long-Term Follow-Up of Intrauterine Growth Restriction: Cardiovascular Disorders

(2013) Elena Demicheva et al.   FETAL DIAGNOSIS AND THERAPY

Frataxin Directly Stimulates Mitochondrial Cysteine Desulfurase by Exposing Substrate-binding Sites, and a Mutant Fe-S Cluster Scaffold Protein with Frataxin-bypassing Ability Acts Similarly

(2013) Alok Pandey et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Gene regulation and epigenetics in Friedreich's ataxia

(2013) Cihangir Yandim et al.   JOURNAL OF NEUROCHEMISTRY

Increasing frataxin gene expression with histone deacetylase inhibitors as a therapeutic approach for Friedreich's ataxia

(2013) Joel M. Gottesfeld et al.   JOURNAL OF NEUROCHEMISTRY

Animal and cellular models of Friedreich ataxia

(2013) Morgane Perdomini et al.   JOURNAL OF NEUROCHEMISTRY

The role of iron and reactive oxygen species in cell death

(2013) Scott J Dixon et al.   Nature Chemical Biology

Reactive Oxygen Species in Vascular Formation and Development

(2013) Yijiang Zhou et al.   Oxidative Medicine and Cellular Longevity

Oxidative stress induces mitochondrial fragmentation in frataxin-deficient cells

(2012) Sophie Lefevre et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

STAR: ultrafast universal RNA-seq aligner

(2012) Alexander Dobin et al.   BIOINFORMATICS

Ferroptosis: An Iron-Dependent Form of Nonapoptotic Cell Death

(2012) Scott J. Dixon et al.   CELL

CTCF: insights into insulator function during development

(2012) M. Herold et al.   DEVELOPMENT

The identification and oxidative stress response of a zeta class glutathione S-transferase (GSTZ1) gene from Apis cerana cerana

(2012) Huiru Yan et al.   JOURNAL OF INSECT PHYSIOLOGY

Skeletal Muscle Involvement in Friedreich Ataxia and Potential Effects of Recombinant Human Erythropoietin Administration on Muscle Regeneration and Neovascularization

(2012) Wolfgang Nachbauer et al.   JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY

CTCFBSDB 2.0: a database for CTCF-binding sites and genome organization

(2012) Jesse D. Ziebarth et al.   NUCLEIC ACIDS RESEARCH

Loss of Maternal CTCF Is Associated with Peri-Implantation Lethality of Ctcf Null Embryos

(2012) James M. Moore et al.   PLoS One

CTCF Is Required for Neural Development and Stochastic Expression of Clustered Pcdh Genes in Neurons

(2012) Teruyoshi Hirayama et al.   Cell Reports

CTCF Promotes Muscle Differentiation by Modulating the Activity of Myogenic Regulatory Factors

(2011) Paul Delgado-Olguín et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The multiple functions of cytochrome c and their regulation in life and death decisions of the mammalian cell: From respiration to apoptosis

(2011) Maik Hüttemann et al.   MITOCHONDRION

Prolonged treatment with pimelic o-aminobenzamide HDAC inhibitors ameliorates the disease phenotype of a Friedreich ataxia mouse model

(2011) Chiranjeevi Sandi et al.   NEUROBIOLOGY OF DISEASE

A Computational Tool for Quantitative Analysis of Vascular Networks

(2011) Enrique Zudaire et al.   PLoS One

Restraint of angiogenesis by zinc finger transcription factor CTCF-dependent chromatin insulation

(2011) M. Tang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Friedreich Ataxia: Molecular Mechanisms, Redox Considerations, and Therapeutic Opportunities

(2010) Renata Santos et al.   ANTIOXIDANTS & REDOX SIGNALING

Functional Analysis of CTCF During Mammalian Limb Development

(2010) Natalia Soshnikova et al.   DEVELOPMENTAL CELL

Impaired myocardial perfusion reserve and fibrosis in Friedreich ataxia: a mitochondrial cardiomyopathy with metabolic syndrome

(2010) S. V. Raman et al.   EUROPEAN HEART JOURNAL

NADPH Oxidase 1 Modulates WNT and NOTCH1 Signaling To Control the Fate of Proliferative Progenitor Cells in the Colon

(2010) Nicolas Coant et al.   MOLECULAR AND CELLULAR BIOLOGY

CTCF: Master Weaver of the Genome

(2009) Jennifer E. Phillips et al.   CELL

Transcriptional Control of Endothelial Cell Development

(2009) Sarah De Val et al.   DEVELOPMENTAL CELL

Chromosome crosstalk in three dimensions

(2009) Anita Göndör et al.   NATURE

Systematic and integrative analysis of large gene lists using DAVID bioinformatics resources

(2009) Da Wei Huang et al.   Nature Protocols

NADPH oxidase isoform selective regulation of endothelial cell proliferation and survival

(2009) Hitesh Peshavariya et al.   NAUNYN-SCHMIEDEBERGS ARCHIVES OF PHARMACOLOGY

Epigenetic Silencing in Friedreich Ataxia Is Associated with Depletion of CTCF (CCCTC-Binding Factor) and Antisense Transcription

(2009) Irene De Biase et al.   PLoS One

Maternal depletion of CTCF reveals multiple functions during oocyte and preimplantation embryo development

(2008) L.-B. Wan et al.   DEVELOPMENT

CTCF regulates cell cycle progression of αβ T cells in the thymus

(2008) Helen Heath et al.   EMBO JOURNAL

HDAC Inhibitors Correct Frataxin Deficiency in a Friedreich Ataxia Mouse Model

(2008) Myriam Rai et al.   PLoS One

Hydrogen peroxide scavenging rescues frataxin deficiency in a Drosophila model of Friedreich's ataxia

(2008) P. R. Anderson et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

HOXA13 Is Essential for Placental Vascular Patterning and Labyrinth Endothelial Specification

(2008) Carley A. E. Shaut et al.   PLoS Genetics