Predicting the carcinogenicity of chemicals with alternative approaches: recent advances

A roadmap for the development of alternative (non-animal) methods for systemic toxicity testing

(2014) David Basketter   ALTEX-Alternatives to Animal Experimentation

Nongenotoxic Carcinogenicity of Chemicals: Mechanisms of Action and Early Recognition through a New Set of Structural Alerts

(2013) Romualdo Benigni et al.   CHEMICAL REVIEWS

Evaluation of the Toxicity Forecasting Capability of EPA's ToxCast Phase I Data: Can ToxCast In Vitro Assays Predict Carcinogenicity?

(2013) ROMUALDO BENIGNI   JOURNAL OF ENVIRONMENTAL SCIENCE AND HEALTH PART C-ENVIRONMENTAL CARCINOGENESIS & ECOTOXICOLOGY REVIEWS

IARC Classes 1 and 2 carcinogens are successfully identified by an alternative strategy that detects DNA-reactivity and cell transformation ability of chemicals

(2013) Romualdo Benigni et al.   MUTATION RESEARCH-GENETIC TOXICOLOGY AND ENVIRONMENTAL MUTAGENESIS

Alternatives to the carcinogenicity bioassay for toxicity prediction: are we there yet?

(2012) Romualdo Benigni   Expert Opinion on Drug Metabolism & Toxicology

In vitro cell transformation assays for an integrated, alternative assessment of carcinogenicity: a data-based analysis

(2012) Romualdo Benigni et al.   MUTAGENESIS

In Vitro Perturbations of Targets in Cancer Hallmark Processes Predict Rodent Chemical Carcinogenesis

(2012) Nicole C. Kleinstreuer et al.   TOXICOLOGICAL SCIENCES

A Comprehensive Statistical Analysis of Predicting In Vivo Hazard Using High-Throughput In Vitro Screening

(2012) Russell S. Thomas et al.   TOXICOLOGICAL SCIENCES

Mechanisms of Chemical Carcinogenicity and Mutagenicity: A Review with Implications for Predictive Toxicology

(2011) Romualdo Benigni et al.   CHEMICAL REVIEWS

Cell transformation assays for prediction of carcinogenic potential: state of the science and future research needs

(2011) S. Creton et al.   MUTAGENESIS

Alternative strategies for carcinogenicity assessment: an efficient and simplified approach based on in vitro mutagenicity and cell transformation assays

(2011) R. Benigni et al.   MUTAGENESIS

The new ISSMIC database on in vivo micronucleus and its role in assessing genotoxicity testing strategies

(2011) R. Benigni et al.   MUTAGENESIS

ECVAM prevalidation study on in vitro cell transformation assays: General outline and conclusions of the study

(2011) Raffaella Corvi et al.   MUTATION RESEARCH-GENETIC TOXICOLOGY AND ENVIRONMENTAL MUTAGENESIS

Testing for Carcinogens: Shift From Animals to Automation Gathers Steam—Slowly

(2009) Charlie Schmidt   JNCI-Journal of the National Cancer Institute

Mechanisms of non-genotoxic carcinogens and importance of a weight of evidence approach

(2009) Lya G. Hernández et al.   MUTATION RESEARCH-REVIEWS IN MUTATION RESEARCH

Using chemical categories to fill data gaps in hazard assessment

(2009) K. van Leeuwen et al.   SAR AND QSAR IN ENVIRONMENTAL RESEARCH

Evaluation of the ability of a battery of three in vitro genotoxicity tests to discriminate rodent carcinogens and non-carcinogens

(2008) David Kirkland et al.   MUTATION RESEARCH-GENETIC TOXICOLOGY AND ENVIRONMENTAL MUTAGENESIS

Toxicity Testing in the 21st Century: Implications for Human Health Risk Assessment

(2008) Robert J. Kavlock et al.   RISK ANALYSIS

ACToR — Aggregated Computational Toxicology Resource

(2008) Richard Judson et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY