The Effects of Chronic Exposure to Ambient Traffic-Related Air Pollution on Alzheimer’s Disease Phenotypes in Wildtype and Genetically Predisposed Male and Female Rats

Opposite changes in APP processing and human Aβ levels in rats carrying either a protective or a pathogenic APP mutation

(2020) Marc D Tambini et al.   eLife

Reduced repressive epigenetic marks, increased DNA damage and Alzheimer's disease hallmarks in the brain of humans and mice exposed to particulate urban air pollution

(2020) Lilian Calderón-Garcidueñas et al.   ENVIRONMENTAL RESEARCH

Effects of early life exposure to traffic-related air pollution on brain development in juvenile Sprague-Dawley rats

(2020) Kelley T. Patten et al.   Translational Psychiatry

Air Pollution Neurotoxicity in the Adult Brain: Emerging Concepts from Experimental Findings

(2020) Amin Haghani et al.   JOURNAL OF ALZHEIMERS DISEASE

Sex-driven modifiers of Alzheimer risk

(2020) Aneela Rahman et al.   NEUROLOGY

Effects of air pollution on the nervous system and its possible role in neurodevelopmental and neurodegenerative disorders

(2020) Lucio G. Costa et al.   PHARMACOLOGY & THERAPEUTICS

Mouse brain transcriptome responses to inhaled nanoparticulate matter differed by sex and APOE in Nrf2-Nfkb interactions

(2020) Amin Haghani et al.   eLife

Adult mouse hippocampal transcriptome changes associated with long-term behavioral and metabolic effects of gestational air pollution toxicity

(2020) Amin Haghani et al.   Translational Psychiatry

Air Pollution and Alzheimer’s Disease: A Systematic Review and Meta-Analysis

(2020) Pengfei Fu et al.   JOURNAL OF ALZHEIMERS DISEASE

Developmental exposure to near roadway pollution produces behavioral phenotypes relevant to neurodevelopmental disorders in juvenile rats

(2020) Elizabeth L. Berg et al.   Translational Psychiatry

Pathological Cardiopulmonary Evaluation of Rats Chronically Exposed to Traffic-Related Air Pollution

(2020) Sabrina Edwards et al.   ENVIRONMENTAL HEALTH PERSPECTIVES

Gene-environment interactions in Alzheimer's disease: A potential path to precision medicine

(2019) Aseel Eid et al.   PHARMACOLOGY & THERAPEUTICS

Genetic meta-analysis of diagnosed Alzheimer’s disease identifies new risk loci and implicates Aβ, tau, immunity and lipid processing

(2019) Brian W. Kunkle et al.   NATURE GENETICS

Air Pollution and Dementia: A Systematic Review

(2019) Ruth Peters et al.   JOURNAL OF ALZHEIMERS DISEASE

Humanising the mouse genome piece by piece

(2019) Fei Zhu et al.   Nature Communications

The Major Risk Factors for Alzheimer’s Disease: Age, Sex, and Genes Modulate the Microglia Response to Aβ Plaques

(2019) Carlo Sala Frigerio et al.   Cell Reports

Combustion- and friction-derived magnetic air pollution nanoparticles in human hearts

(2019) Lilian Calderón-Garcidueñas et al.   ENVIRONMENTAL RESEARCH

Combustion and friction-derived nanoparticles and industrial-sourced nanoparticles: The culprit of Alzheimer and Parkinson's diseases.

(2019) Lilian Calderón-Garcidueñas et al.   ENVIRONMENTAL RESEARCH

Gene-by-environment interactions in Alzheimer’s disease and Parkinson’s disease

(2019) Amy R. Dunn et al.   NEUROSCIENCE AND BIOBEHAVIORAL REVIEWS

Regional differences in Alzheimer’s disease pathology confound behavioural rescue after amyloid-β attenuation

(2019) Christopher D Morrone et al.   BRAIN

Amyloid-β-independent regulators of tau pathology in Alzheimer disease

(2019) Rik van der Kant et al.   NATURE REVIEWS NEUROSCIENCE

Selective memory and behavioral alterations after ambient ultrafine particulate matter exposure in aged 3xTgAD Alzheimer’s disease mice

(2019) Katrina Jew et al.   Particle and Fibre Toxicology

Traffic-related air pollutants (TRAP-PM) promote neuronal amyloidogenesis through oxidative damage to lipid rafts

(2019) Mafalda Cacciottolo et al.   FREE RADICAL BIOLOGY AND MEDICINE

Gender Difference in the Effects of Outdoor Air Pollution on Cognitive Function Among Elderly in Korea

(2019) Hyunmin Kim et al.   Frontiers in Public Health

Acute exposure to diesel exhaust impairs adult neurogenesis in mice: prominence in males and protective effect of pioglitazone

(2018) Jacki L. Coburn et al.   ARCHIVES OF TOXICOLOGY

Sex-Specific Features of Microglia from Adult Mice

(2018) Alessandro Villa et al.   Cell Reports

The emerging risk of exposure to air pollution on cognitive decline and Alzheimer's disease – Evidence from epidemiological and animal studies

(2018) Jason Kilian et al.   Biomedical Journal

Air pollution and brain health

(2018) Tom C. Russ et al.   CURRENT OPINION IN PSYCHIATRY

Enhanced cerebellar myelination with concomitant iron elevation and ultrastructural irregularities following prenatal exposure to ambient particulate matter in the mouse

(2018) Carolyn Klocke et al.   INHALATION TOXICOLOGY

Water-exchange MRI detects subtle blood-brain barrier breakdown in Alzheimer's disease rats

(2018) Ben R. Dickie et al.   NEUROIMAGE

Combustion-Derived Nanoparticles in Key Brain Target Cells and Organelles in Young Urbanites: Culprit Hidden in Plain Sight in Alzheimer’s Disease Development

(2017) Angélica González-Maciel et al.   JOURNAL OF ALZHEIMERS DISEASE

Toll-like receptor 4 in glial inflammatory responses to air pollution in vitro and in vivo

(2017) Nicholas C. Woodward et al.   Journal of Neuroinflammation

Cell-specific deletion of C1qa identifies microglia as the dominant source of C1q in mouse brain

(2017) Maria I. Fonseca et al.   Journal of Neuroinflammation

Living close to heavy traffic roads, air pollution, and dementia

(2017) Lilian Calderón-Garcidueñas et al.   LANCET

Microglia-derived ASC specks cross-seed amyloid-β in Alzheimer’s disease

(2017) Carmen Venegas et al.   NATURE

Traffic-related air pollution impact on mouse brain accelerates myelin and neuritic aging changes with specificity for CA1 neurons

(2017) Nicholas C. Woodward et al.   NEUROBIOLOGY OF AGING

Diesel engine exhaust accelerates plaque formation in a mouse model of Alzheimer’s disease

(2017) Maja Hullmann et al.   Particle and Fibre Toxicology

Particulate air pollutants, APOE alleles and their contributions to cognitive impairment in older women and to amyloidogenesis in experimental models

(2017) M Cacciottolo et al.   Translational Psychiatry

Early neurovascular dysfunction in a transgenic rat model of Alzheimer’s disease

(2017) Illsung L. Joo et al.   Scientific Reports

Genomic variants, genes, and pathways of Alzheimer's disease: An overview

(2016) Adam C. Naj et al.   AMERICAN JOURNAL OF MEDICAL GENETICS PART B-NEUROPSYCHIATRIC GENETICS

Effects of Ambient Air Pollution Exposure on Olfaction: A Review

(2016) Gaurav S. Ajmani et al.   ENVIRONMENTAL HEALTH PERSPECTIVES

Magnetite pollution nanoparticles in the human brain

(2016) Barbara A. Maher et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Complement and microglia mediate early synapse loss in Alzheimer mouse models

(2016) S. Hong et al.   SCIENCE

Sex and genetic differences in the effects of acute diesel exhaust exposure on inflammation and oxidative stress in mouse brain

(2016) Toby B. Cole et al.   TOXICOLOGY

A hyperspectral method to assay the microphysiological fates of nanomaterials in histological samples

(2016) Elliott D SoRelle et al.   eLife

The amyloid-beta forming tripeptide cleavage mechanism of γ-secretase

(2016) David M Bolduc et al.   eLife

NO2 inhalation promotes Alzheimer’s disease-like progression: cyclooxygenase-2-derived prostaglandin E2 modulation and monoacylglycerol lipase inhibition-targeted medication

(2016) Wei Yan et al.   Scientific Reports

An Unexpected Transient Breakdown of the Blood Brain Barrier Triggers Passage of Large Intravenously Administered Nanoparticles

(2016) Nicole M. Smith et al.   Scientific Reports

Pulmonary inflammatory effects of source-oriented particulate matter from California's San Joaquin Valley

(2015) Laurel E. Plummer et al.   ATMOSPHERIC ENVIRONMENT

Allergic Airway Inflammation is Differentially Exacerbated by Daytime and Nighttime Ultrafine and Submicron Fine Ambient Particles: Heme Oxygenase-1 as an Indicator of PM-Mediated Allergic Inflammation

(2015) Christopher M. Carosino et al.   JOURNAL OF TOXICOLOGY AND ENVIRONMENTAL HEALTH-PART A-CURRENT ISSUES

Distribution and accumulation of 10 nm silver nanoparticles in maternal tissues and visceral yolk sac of pregnant mice, and a potential effect on embryo growth

(2015) Carlye A. Austin et al.   Nanotoxicology

Il10 Deficiency Rebalances Innate Immunity to Mitigate Alzheimer-Like Pathology

(2015) Marie-Victoire Guillot-Sestier et al.   NEURON

Blood-Brain Barrier Breakdown in the Aging Human Hippocampus

(2015) Axel Montagne et al.   NEURON

Cyclic Ozone Exposure Induces Gender-Dependent Neuropathology and Memory Decline in an Animal Model of Alzheimer’s Disease

(2015) Hasina Akhter et al.   TOXICOLOGICAL SCIENCES

A Pilot Study to Assess Effects of Long-Term Inhalation of Airborne Particulate Matter on Early Alzheimer-Like Changes in the Mouse Brain

(2015) Dhaval P. Bhatt et al.   PLoS One

Monoclonal Antibodies against Aβ42 Fibrils Distinguish Multiple Aggregation State Polymorphismsin Vitroand in Alzheimer Disease Brain

(2014) Asa Hatami et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

A Dramatic Increase of C1q Protein in the CNS during Normal Aging

(2013) A. H. Stephan et al.   JOURNAL OF NEUROSCIENCE

A Transgenic Alzheimer Rat with Plaques, Tau Pathology, Behavioral Impairment, Oligomeric A , and Frank Neuronal Loss

(2013) R. M. Cohen et al.   JOURNAL OF NEUROSCIENCE

Meta-analysis of 74,046 individuals identifies 11 new susceptibility loci for Alzheimer's disease

(2013) Jean-Charles Lambert et al.   NATURE GENETICS

Novel object recognition ability in female mice following exposure to nanoparticle-rich diesel exhaust

(2012) Tin-Tin Win-Shwe et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

Diesel Exhaust Activates and Primes Microglia: Air Pollution, Neuroinflammation, and Regulation of Dopaminergic Neurotoxicity

(2011) Shannon Levesque et al.   ENVIRONMENTAL HEALTH PERSPECTIVES

Nanoparticles and Neurotoxicity

(2011) Tin-Tin Win-Shwe et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Air pollution & the brain: Subchronic diesel exhaust exposure causes neuroinflammation and elevates early markers of neurodegenerative disease

(2011) Shannon Levesque et al.   Journal of Neuroinflammation

The Role of Microglia in the Healthy Brain

(2011) M.-E. Tremblay et al.   JOURNAL OF NEUROSCIENCE

Air pollution impairs cognition, provokes depressive-like behaviors and alters hippocampal cytokine expression and morphology

(2011) L K Fonken et al.   MOLECULAR PSYCHIATRY

Intracellular uptake and associated toxicity of silver nanoparticles in Caenorhabditis elegans

(2010) Joel N. Meyer et al.   AQUATIC TOXICOLOGY

Atmospheric Processes Influencing Aerosols Generated by Combustion and the Inference of Their Impact on Public Exposure: A Review

(2009) Zhi Ning et al.   Aerosol and Air Quality Research

A Growing Role for Gender Analysis in Air Pollution Epidemiology

(2009) Jane E. Clougherty   ENVIRONMENTAL HEALTH PERSPECTIVES

Chemicals present in automobile traffic tunnels and the possible community health hazards: A review of the literature

(2009) Jim R. Kuykendall et al.   INHALATION TOXICOLOGY

Size-resolved particle number and volume emission factors for on-road gasoline and diesel motor vehicles

(2009) George A. Ban-Weiss et al.   JOURNAL OF AEROSOL SCIENCE

Air pollution: mechanisms of neuroinflammation and CNS disease

(2009) Michelle L. Block et al.   TRENDS IN NEUROSCIENCES