Toll-like receptor 4 in glial inflammatory responses to air pollution in vitro and in vivo

Nanoscale Particulate Matter from Urban Traffic Rapidly Induces Oxidative Stress and Inflammation in Olfactory Epithelium with Concomitant Effects on Brain

(2016) Hank Cheng et al.   ENVIRONMENTAL HEALTH PERSPECTIVES

Microglial priming through the lung–brain axis: the role of air pollution–induced circulating factors

(2016) Christen L. Mumaw et al.   FASEB JOURNAL

A Voxel-Based Morphometry Study Reveals Local Brain Structural Alterations Associated with Ambient Fine Particles in Older Women

(2016) Ramon Casanova et al.   Frontiers in Human Neuroscience

Salvianolic Acid B Ameliorates Cerebral Ischemia/Reperfusion Injury Through Inhibiting TLR4/MyD88 Signaling Pathway

(2016) Yujue Wang et al.   INFLAMMATION

Stimulation of TLR4 Attenuates Alzheimer’s Disease–Related Symptoms and Pathology in Tau-Transgenic Mice

(2016) Yiren Qin et al.   JOURNAL OF IMMUNOLOGY

Urban traffic-derived nanoparticulate matter reduces neurite outgrowth via TNFα in vitro

(2016) Hank Cheng et al.   Journal of Neuroinflammation

The Role of Toll-Like Receptor 4 in Infectious and Noninfectious Inflammation

(2016) Monica Molteni et al.   MEDIATORS OF INFLAMMATION

Stroke Damage Is Exacerbated by Nano-Size Particulate Matter in a Mouse Model

(2016) Qinghai Liu et al.   PLoS One

Ambient air pollution and neurotoxicity on brain structure: Evidence from women's health initiative memory study

(2015) Jiu-Chiuan Chen et al.   ANNALS OF NEUROLOGY

Combined Effects of Fine Particulate Matter and Lipopolysaccharide on Apoptotic Responses in NR8383 Macrophages

(2015) Qi Xiong et al.   JOURNAL OF TOXICOLOGY AND ENVIRONMENTAL HEALTH-PART A-CURRENT ISSUES

Effects of Prenatal Exposure to Air Pollutants (Polycyclic Aromatic Hydrocarbons) on the Development of Brain White Matter, Cognition, and Behavior in Later Childhood

(2015) Bradley S. Peterson et al.   JAMA Psychiatry

Induction of a common microglia gene expression signature by aging and neurodegenerative conditions: a co-expression meta-analysis

(2015) Inge R Holtman et al.   Acta Neuropathologica Communications

Characterizing the genetic basis of innate immune response in TLR4-activated human monocytes

(2014) Sarah Kim et al.   Nature Communications

Separate enrichment analysis of pathways for up- and downregulated genes

(2013) G. Hong et al.   Journal of the Royal Society Interface

Microarray and Pathway Analysis Reveal Distinct Mechanisms Underlying Cannabinoid-Mediated Modulation of LPS-Induced Activation of BV-2 Microglial Cells

(2013) Ana Juknat et al.   PLoS One

Prenatal Polycyclic Aromatic Hydrocarbon (PAH) Exposure and Child Behavior at Age 6–7 Years

(2012) Frederica P. Perera et al.   ENVIRONMENTAL HEALTH PERSPECTIVES

Nrf2-regulated phase II enzymes are induced by chronic ambient nanoparticle exposure in young mice with age-related impairments

(2012) Hongqiao Zhang et al.   FREE RADICAL BIOLOGY AND MEDICINE

Microglia are required for astroglial toll-like receptor 4 response and for optimal TLR2 and TLR3 response

(2012) Thomas H. Holm et al.   GLIA

Exposure to severe urban air pollution influences cognitive outcomes, brain volume and systemic inflammation in clinically healthy children

(2011) Lilian Calderón-Garcidueñas et al.   BRAIN AND COGNITION

Glutamatergic Neurons in Rodent Models Respond to Nanoscale Particulate Urban Air Pollutants in Vivo and in Vitro

(2011) Todd E. Morgan et al.   ENVIRONMENTAL HEALTH PERSPECTIVES

Diesel Exhaust Activates and Primes Microglia: Air Pollution, Neuroinflammation, and Regulation of Dopaminergic Neurotoxicity

(2011) Shannon Levesque et al.   ENVIRONMENTAL HEALTH PERSPECTIVES

Toll-like receptors 2 and 4 in ischemic stroke: Outcome and therapeutic values

(2011) David Brea et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

Air pollution impairs cognition, provokes depressive-like behaviors and alters hippocampal cytokine expression and morphology

(2011) L K Fonken et al.   MOLECULAR PSYCHIATRY

Weighted Correlation Network Analysis (WGCNA) Applied to the Tomato Fruit Metabolome

(2011) Matthew V. DiLeo et al.   PLoS One

Microglia activation triggers astrocyte-mediated modulation of excitatory neurotransmission

(2011) O. Pascual et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Traffic-Related Air Pollution and Cognitive Function in a Cohort of Older Men

(2010) Melinda C. Power et al.   ENVIRONMENTAL HEALTH PERSPECTIVES

Endotoxin and polycyclic aromatic hydrocarbons in ambient fine particulate matter from Fresno, California initiate human monocyte inflammatory responses mediated by reactive oxygen species

(2010) L.J. den Hartigh et al.   TOXICOLOGY IN VITRO

Associations of Environmental Factors With Elderly Health and Mortality in China

(2009) Yi Zeng et al.   AMERICAN JOURNAL OF PUBLIC HEALTH

ClueGO: a Cytoscape plug-in to decipher functionally grouped gene ontology and pathway annotation networks

(2009) Gabriela Bindea et al.   BIOINFORMATICS

Long-term exposure to traffic-related particulate matter impairs cognitive function in the elderly

(2009) Ulrich Ranft et al.   ENVIRONMENTAL RESEARCH

Microarray analysis of gene expression profile by treatment of Cinnamomi Ramulus in lipopolysaccharide-stimulated BV-2 cells

(2009) Se-Hee Hwang et al.   GENE

Involvement of TLR2 and TLR4 in inflammatory immune responses induced by fine and coarse ambient air particulate matter

(2009) Joanna Shoenfelt et al.   JOURNAL OF LEUKOCYTE BIOLOGY

Air pollution: mechanisms of neuroinflammation and CNS disease

(2009) Michelle L. Block et al.   TRENDS IN NEUROSCIENCES

WGCNA: an R package for weighted correlation network analysis

(2008) Peter Langfelder et al.   BMC BIOINFORMATICS

Toll-like receptor 4-dependent upregulation of cytokines in a transgenic mouse model of Alzheimer's disease

(2008) Jing-Ji Jin et al.   Journal of Neuroinflammation

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(2008) Bart Ferwerda et al.   MOLECULAR MEDICINE

Long-term Air Pollution Exposure Is Associated with Neuroinflammation, an Altered Innate Immune Response, Disruption of the Blood-Brain Barrier, Ultrafine Particulate Deposition, and Accumulation of Amyloid β-42 and α-Synuclein in Children and Young Adults

(2008) Lilian Calderón-Garcidueñas et al.   TOXICOLOGIC PATHOLOGY

Inhaled ultrafine particulate matter affects CNS inflammatory processes and may act via MAP kinase signaling pathways

(2008) M.T. Kleinman et al.   TOXICOLOGY LETTERS