Membrane lipid rafts and neurobiology: age-related changes in membrane lipids and loss of neuronal function

Alterations in Brain Cholesterol Metabolism in the APPSLxPS1mut mouse, a Model for Alzheimer's Disease

(2017) Tim Vanmierlo et al.   JOURNAL OF ALZHEIMERS DISEASE

27-Hydroxycholesterol mediates negative effects of dietary cholesterol on cognition in mice

(2015) Maura Heverin et al.   BEHAVIOURAL BRAIN RESEARCH

Safety and tolerability of intracerebroventricular PDGF-BB in Parkinson’s disease patients

(2015) Gesine Paul et al.   JOURNAL OF CLINICAL INVESTIGATION

Long-term atorvastatin treatment leads to alterations in behavior, cognition, and hippocampal biochemistry

(2014) Jan M. Schilling et al.   BEHAVIOURAL BRAIN RESEARCH

Cholesterol in brain disease: sometimes determinant and frequently implicated

(2014) M. G. Martin et al.   EMBO REPORTS

Young blood reverses age-related impairments in cognitive function and synaptic plasticity in mice

(2014) Saul A Villeda et al.   NATURE MEDICINE

What is normal in normal aging? Effects of aging, amyloid and Alzheimer's disease on the cerebral cortex and the hippocampus

(2014) Anders M. Fjell et al.   PROGRESS IN NEUROBIOLOGY

Neuroprotective effects of physical activity on the brain: a closer look at trophic factor signaling

(2014) Cristy Phillips et al.   Frontiers in Cellular Neuroscience

Synaptic Health

(2014) John H. Morrison et al.   JAMA Psychiatry

Perturbations of neural circuitry in aging, mild cognitive impairment, and Alzheimer's disease

(2013) Stephanie L. Leal et al.   AGEING RESEARCH REVIEWS

Interaction of membrane/lipid rafts with the cytoskeleton: Impact on signaling and function

(2013) Brian P. Head et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES

Motor rehabilitation in stroke and traumatic brain injury

(2013) Erika Y. Breceda et al.   CURRENT OPINION IN NEUROLOGY

Phosphodiesterase Inhibition Rescues Chronic Cognitive Deficits Induced by Traumatic Brain Injury

(2013) D. J. Titus et al.   JOURNAL OF NEUROSCIENCE

Reduced neuroplasticity in aged rats: a role for the neurotrophin brain-derived neurotrophic factor

(2013) Francesca Calabrese et al.   NEUROBIOLOGY OF AGING

Critical ages in the life course of the adult brain: nonlinear subcortical aging

(2013) Anders M. Fjell et al.   NEUROBIOLOGY OF AGING

Is It Possible to Improve Memory Function by Upregulation of the Cholesterol 24S-Hydroxylase (CYP46A1) in the Brain?

(2013) Silvia Maioli et al.   PLoS One

How Slow Is the Transbilayer Diffusion (Flip-Flop) of Cholesterol?

(2012) Theodore L. Steck et al.   BIOPHYSICAL JOURNAL

Age-dependent alterations in cAMP signaling contribute to synaptic plasticity deficits following traumatic brain injury

(2012) D.J. Titus et al.   NEUROSCIENCE

Effects of early rolipram treatment on histopathological outcome after controlled cortical impact injury in mice

(2012) Coleen M. Atkins et al.   NEUROSCIENCE LETTERS

Noninvasive Neutron Scattering Measurements Reveal Slower Cholesterol Transport in Model Lipid Membranes

(2011) S. Garg et al.   BIOPHYSICAL JOURNAL

Neuron-targeted Caveolin-1 Protein Enhances Signaling and Promotes Arborization of Primary Neurons

(2011) Brian P. Head et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Sphingomyelin upregulation in mature neurons contributes to TrkB activity by Rac1 endocytosis

(2011) L. Trovo et al.   JOURNAL OF CELL SCIENCE

Marked accumulation of 27-hydroxycholesterol in the brains of Alzheimer's patients with the Swedish APP 670/671 mutation

(2011) Marjan Shafaati et al.   JOURNAL OF LIPID RESEARCH

Regulation of tyrosine kinase B activity by the Cyp46/cholesterol loss pathway in mature hippocampal neurons: relevance for neuronal survival under stress and in aging

(2011) Alejandro O. Sodero et al.   JOURNAL OF NEUROCHEMISTRY

Inhibition of neuronal cholesterol biosynthesis with lovastatin leads to impaired synaptic vesicle release even in the presence of lipoproteins or geranylgeraniol

(2011) Tiffany Mailman et al.   JOURNAL OF NEUROCHEMISTRY

Cholesterol asymmetry in synaptic plasma membranes

(2011) W. Gibson Wood et al.   JOURNAL OF NEUROCHEMISTRY

Lipid changes in the aged brain: Effect on synaptic function and neuronal survival

(2011) María Dolores Ledesma et al.   PROGRESS IN LIPID RESEARCH

Isolation rearing-induced deficits in contextual fear learning do not require CRF2 receptors

(2010) Jodi E. Gresack et al.   BEHAVIOURAL BRAIN RESEARCH

Co-segregation of AMPA receptors with GM1ganglioside in synaptosomal membrane subfractions

(2010) Andy A. Cole et al.   BIOCHEMICAL JOURNAL

Formation and function of apolipoprotein E-containing lipoproteins in the nervous system

(2010) Jean E. Vance et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS

Brain cholesterol in normal and pathological aging

(2010) Mauricio Martin et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS

Neuronal polarization: The cytoskeleton leads the way

(2010) Michael Stiess et al.   Developmental Neurobiology

Cholesterol reduction impairs exocytosis of synaptic vesicles

(2010) A. Linetti et al.   JOURNAL OF CELL SCIENCE

Seladin-1/DHCR24 protects neuroblastoma cells against Aβ toxicity by increasing membrane cholesterol content

(2010) C. Cecchi et al.   JOURNAL OF CELLULAR AND MOLECULAR MEDICINE

The novel protein MANI modulates neurogenesis and neurite-cone growth

(2010) Manisha Mishra et al.   JOURNAL OF CELLULAR AND MOLECULAR MEDICINE

Genetic connections between neurological disorders and cholesterol metabolism

(2010) Ingemar Björkhem et al.   JOURNAL OF LIPID RESEARCH

Heterogeneous intrastriatal pattern of proteins regulating axon growth in normal adult human brain

(2010) Junchao Tong et al.   NEUROBIOLOGY OF DISEASE

Modulators of Cytoskeletal Reorganization in CA1 Hippocampal Neurons Show Increased Expression in Patients at Mid-Stage Alzheimer's Disease

(2010) Patricia F. Kao et al.   PLoS One

Loss of Caveolin-1 Accelerates Neurodegeneration and Aging

(2010) Brian P. Head et al.   PLoS One

The Growth Cone Cytoskeleton in Axon Outgrowth and Guidance

(2010) E. W. Dent et al.   Cold Spring Harbor Perspectives in Biology

Rho and Ras GTPases in Axon Growth, Guidance, and Branching

(2010) A. Hall et al.   Cold Spring Harbor Perspectives in Biology

Increase in sphingolipid catabolic enzyme activity during aging

(2009) Santosh J Sacket et al.   ACTA PHARMACOLOGICA SINICA

Cholesterol 24-Hydroxylase: An Enzyme of Cholesterol Turnover in the Brain

(2009) David W. Russell et al.   Annual Review of Biochemistry

Sphingolipid/cholesterol regulation of neurotransmitter receptor conformation and function

(2009) Jacques Fantini et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES

Sphingolipids and gangliosides of the nervous system in membrane function and dysfunction

(2009) Elena Posse de Chaves et al.   FEBS LETTERS

Control of the Postsynaptic Membrane Viscosity

(2009) M. Renner et al.   JOURNAL OF NEUROSCIENCE

One-Year Brain Atrophy Evident in Healthy Aging

(2009) A. M. Fjell et al.   JOURNAL OF NEUROSCIENCE

cAMP-Dependent Axon Guidance Is Distinctly Regulated by Epac and Protein Kinase A

(2009) A. J. Murray et al.   JOURNAL OF NEUROSCIENCE

Detergent resistant membrane-associated IDE in brain tissue and cultured cells: Relevance to Aβ and insulin degradation

(2009) Ayelén Bulloj et al.   Molecular Neurodegeneration

The trip of the tip: understanding the growth cone machinery

(2009) Laura Anne Lowery et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Age-associated changes in synaptic lipid raft proteins revealed by two-dimensional fluorescence difference gel electrophoresis

(2009) Lei Jiang et al.   NEUROBIOLOGY OF AGING

Deficits in ERK and CREB activation in the hippocampus after traumatic brain injury

(2009) Coleen M. Atkins et al.   NEUROSCIENCE LETTERS

Age-dependent high-density clustering of GM1 ganglioside at presynaptic neuritic terminals promotes amyloid β-protein fibrillogenesis

(2008) Naoki Yamamoto et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES

Are specific nonannular cholesterol binding sites present in G-protein coupled receptors?

(2008) Yamuna Devi Paila et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES

Cholesterol depletion inhibits synaptic transmission and synaptic plasticity in rat hippocampus

(2008) C. Frank et al.   EXPERIMENTAL NEUROLOGY

Neuroprotective effects of the Alzheimer's disease-related gene seladin-1

(2008) Alessandro Peri et al.   JOURNAL OF MOLECULAR ENDOCRINOLOGY

Striatal β-Amyloid Deposition in Parkinson Disease With Dementia

(2008) Michail E. Kalaitzakis et al.   JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY

Cholesterol Loss Enhances TrkB Signaling in Hippocampal Neurons Aging in Vitro

(2008) Mauricio G. Martin et al.   MOLECULAR BIOLOGY OF THE CELL

Leaky synapses: Regulation of spontaneous neurotransmission in central synapses

(2008) C.R. Wasser et al.   NEUROSCIENCE

Caveolin-1 expression is essential for N-methyl-d-aspartate receptor-mediated Src and extracellular signal-regulated kinase 1/2 activation and protection of primary neurons from ischemic cell death

(2007) Brian P. Head et al.   FASEB JOURNAL