The mystery of C. elegans aging: An emerging role for fat

Modulation of lipid biosynthesis contributes to stress resistance and longevity of C. elegans mutants

(2016) Robert J. Shmookler Reis et al.   Aging-US

Longevity pathways converge on autophagy genes to regulate life span inCaenorhabditis elegans

(2014) Márton L. Tóth et al.   Autophagy

New genes that extend Caenorhabditis elegans’ lifespan in response to reproductive signals

(2011) Mark McCormick et al.   AGING CELL

Loss of intestinal nuclei and intestinal integrity in aging C. elegans

(2011) Matthew D. McGee et al.   AGING CELL

The free-radical damage theory: Accumulating evidence against a simple link of oxidative stress to ageing and lifespan

(2011) John R. Speakman et al.   BIOESSAYS

Antioxidant defense and aging inC. elegans: Is the oxidative damage theory of aging wrong?

(2011) David Gems et al.   CELL CYCLE

Autophagy and Lipid Metabolism Coordinately Modulate Life Span in Germline-less C. elegans

(2011) Louis R. Lapierre et al.   CURRENT BIOLOGY

Increased life span from overexpression of superoxide dismutase in Caenorhabditis elegans is not caused by decreased oxidative damage

(2011) Filipe Cabreiro et al.   FREE RADICAL BIOLOGY AND MEDICINE

Fatty Acid Desaturation Links Germ Cell Loss to Longevity Through NHR-80/HNF4 in C. elegans

(2011) Jérôme Goudeau et al.   PLOS BIOLOGY

Reactive Oxygen Species and Aging in Caenorhabditis elegans: Causal or Casual Relationship?

(2010) Jeremy Michael Van Raamsdonk et al.   ANTIOXIDANTS & REDOX SIGNALING

Aging: ROS or TOR

(2010) Mikhail V Blagosklonny   CELL CYCLE

With TOR, Less Is More: A Key Role for the Conserved Nutrient-Sensing TOR Pathway in Aging

(2010) Pankaj Kapahi et al.   Cell Metabolism

The genetics of ageing

(2010) Cynthia J. Kenyon   NATURE

Gluttony, sloth and the metabolic syndrome: a roadmap to lipotoxicity

(2010) Roger H. Unger et al.   TRENDS IN ENDOCRINOLOGY AND METABOLISM

A Mitochondrial Superoxide Signal Triggers Increased Longevity in Caenorhabditis elegans

(2010) Wen Yang et al.   PLOS BIOLOGY

Is the oxidative stress theory of aging dead?

(2009) Viviana I. Pérez et al.   BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS

Role of visceral adipose tissue in aging

(2009) Derek M. Huffman et al.   BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS

C. elegans Major Fats Are Stored in Vesicles Distinct from Lysosome-Related Organelles

(2009) Eyleen J. O'Rourke et al.   Cell Metabolism

Autophagy regulates lipid metabolism

(2009) Rajat Singh et al.   NATURE

The conserved NAD(H)-dependent corepressor CTBP-1 regulates Caenorhabditis elegans life span

(2009) S. Chen et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Ribosomal Protein S6 Kinase 1 Signaling Regulates Mammalian Life Span

(2009) C. Selman et al.   SCIENCE

A Role for Autophagy in the Extension of Lifespan by Dietary Restriction in C. elegans

(2008) Malene Hansen et al.   PLoS Genetics

Fat Metabolism Links Germline Stem Cells and Longevity in C. elegans

(2008) M. C. Wang et al.   SCIENCE