Autophagy-mediated longevity is modulated by lipoprotein biogenesis

Modulation of lipid biosynthesis contributes to stress resistance and longevity of C. elegans mutants

(2016) Robert J. Shmookler Reis et al.   Aging-US

Transcriptional and epigenetic regulation of autophagy in aging

(2015) Louis R Lapierre et al.   Autophagy

Widespread Proteome Remodeling and Aggregation in Aging C. elegans

(2015) Dirk M. Walther et al.   CELL

Lysosomal signaling molecules regulate longevity in Caenorhabditis elegans

(2015) A. Folick et al.   SCIENCE

WIPI-Mediated Autophagy and Longevity

(2015) Mona Grimmel et al.   Cells

Exome sequencing of three cases of familial exceptional longevity

(2014) Timothy P. Cash et al.   AGING CELL

A sterol-enriched vacuolar microdomain mediates stationary phase lipophagy in budding yeast

(2014) Chao-Wen Wang et al.   JOURNAL OF CELL BIOLOGY

Transcriptional regulation of autophagy by an FXR–CREB axis

(2014) Sunmi Seok et al.   NATURE

Nutrient-sensing nuclear receptors coordinate autophagy

(2014) Jae Man Lee et al.   NATURE

Steroid hormone signalling links reproduction to lifespan in dietary-restricted Caenorhabditis elegans

(2014) Manjunatha Thondamal et al.   Nature Communications

Germline Signals Deploy NHR-49 to Modulate Fatty-Acid β-Oxidation and Desaturation in Somatic Tissues of C. elegans

(2014) Ramesh Ratnappan et al.   PLoS Genetics

Autophagy genes are required for normal lipid levels inC. elegans

(2013) Louis R. Lapierre et al.   Autophagy

The NHR-8 Nuclear Receptor Regulates Cholesterol and Bile Acid Homeostasis in C. elegans

(2013) Daniel B. Magner et al.   Cell Metabolism

Reproduction, Fat Metabolism, and Life Span: What Is the Connection?

(2013) Malene Hansen et al.   Cell Metabolism

 -6 Polyunsaturated fatty acids extend life span through the activation of autophagy

(2013) E. J. O'Rourke et al.   GENES & DEVELOPMENT

TFEB controls cellular lipid metabolism through a starvation-induced autoregulatory loop

(2013) Carmine Settembre et al.   NATURE CELL BIOLOGY

MXL-3 and HLH-30 transcriptionally link lipolysis and autophagy to nutrient availability

(2013) Eyleen J. O’Rourke et al.   NATURE CELL BIOLOGY

DAF-16 employs the chromatin remodeller SWI/SNF to promote stress resistance and longevity

(2013) Christian G. Riedel et al.   NATURE CELL BIOLOGY

The TFEB orthologue HLH-30 regulates autophagy and modulates longevity in Caenorhabditis elegans

(2013) Louis R. Lapierre et al.   Nature Communications

Dietary Restriction Induced Longevity Is Mediated by Nuclear Receptor NHR-62 in Caenorhabditis elegans

(2013) Bree N. Heestand et al.   PLoS Genetics

Autophagy links lipid metabolism to longevity inC. elegans

(2012) Louis R. Lapierre et al.   Autophagy

The mystery of C. elegans aging: An emerging role for fat

(2012) Daniel Ackerman et al.   BIOESSAYS

NSBP-1 mediates the effects of cholesterol on insulin/IGF-1 signaling in Caenorhabditis elegans

(2012) Mi Cheong Cheong et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Lessons from C. elegans: signaling pathways for longevity

(2012) Louis R. Lapierre et al.   TRENDS IN ENDOCRINOLOGY AND METABOLISM

Sterol Regulation of Metabolism, Homeostasis, and Development

(2011) Joshua Wollam et al.   Annual Review of Biochemistry

Regulation of Lipid Droplet Cholesterol Efflux From Macrophage Foam Cells

(2011) Mireille Ouimet et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Autophagy and Lipid Metabolism Coordinately Modulate Life Span in Germline-less C. elegans

(2011) Louis R. Lapierre et al.   CURRENT BIOLOGY

The mevalonate pathway in C. elegans

(2011) Manish Rauthan et al.   Lipids in Health and Disease

Role of AMPK-mTOR-Ulk1/2 in the Regulation of Autophagy: Cross Talk, Shortcuts, and Feedbacks

(2011) S. Alers et al.   MOLECULAR AND CELLULAR BIOLOGY

Fatty Acid Desaturation Links Germ Cell Loss to Longevity Through NHR-80/HNF4 in C. elegans

(2011) Jérôme Goudeau et al.   PLOS BIOLOGY

The autophagosomal protein LGG-2 acts synergistically with LGG-1 in dauer formation and longevity in C. elegans

(2010) Adriana Alberti et al.   Autophagy

Insulin-like Signaling Determines Survival during Stress via Posttranscriptional Mechanisms in C. elegans

(2010) Gawain McColl et al.   Cell Metabolism

With TOR, Less Is More: A Key Role for the Conserved Nutrient-Sensing TOR Pathway in Aging

(2010) Pankaj Kapahi et al.   Cell Metabolism

Should we use apoB for risk assessment and as a target for treatment?

(2010) W. Virgil Brown et al.   Journal of Clinical Lipidology

A Comparative Study of Fat Storage Quantitation in Nematode Caenorhabditis elegans Using Label and Label-Free Methods

(2010) Kelvin Yen et al.   PLoS One

Genome-Wide Identification of Binding Sites Defines Distinct Functions for Caenorhabditis elegans PHA-4/FOXA in Development and Environmental Response

(2010) Mei Zhong et al.   PLoS Genetics

Regulation Mechanisms and Signaling Pathways of Autophagy

(2009) Congcong He et al.   Annual Review of Genetics

C. elegans Major Fats Are Stored in Vesicles Distinct from Lysosome-Related Organelles

(2009) Eyleen J. O'Rourke et al.   Cell Metabolism

Autophagy regulates lipid metabolism

(2009) Rajat Singh et al.   NATURE

Collapse of proteostasis represents an early molecular event in Caenorhabditis elegans aging

(2009) A. Ben-Zvi et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

A Gene Network Regulating Lysosomal Biogenesis and Function

(2009) Marco Sardiello et al.   SCIENCE

Fat synthesis and adiposity regulation in Caenorhabditis elegans

(2009) Jennifer L. Watts   TRENDS IN ENDOCRINOLOGY AND METABOLISM

A 13C Isotope Labeling Strategy Reveals the Influence of Insulin Signaling on Lipogenesis in C. elegans

(2008) Carissa L. Perez et al.   Cell Metabolism

A Role for Autophagy in the Extension of Lifespan by Dietary Restriction in C. elegans

(2008) Malene Hansen et al.   PLoS Genetics

Fat Metabolism Links Germline Stem Cells and Longevity in C. elegans

(2008) M. C. Wang et al.   SCIENCE

The many intersecting pathways underlying apolipoprotein B secretion and degradation

(2008) Jeffrey L. Brodsky et al.   TRENDS IN ENDOCRINOLOGY AND METABOLISM