The many actions of insulin in skeletal muscle, the paramount tissue determining glycemia

Complexin-2 redistributes to the membrane of muscle cells in response to insulin and contributes to GLUT4 translocation

(2021) Martin Alejandro Pavarotti et al.   BIOCHEMICAL JOURNAL

Deep muscle-proteomic analysis of freeze-dried human muscle biopsies reveals fiber type-specific adaptations to exercise training

(2021) A. S. Deshmukh et al.   Nature Communications

Insulin action in adipocytes, adipose remodeling, and systemic effects

(2021) Anna Santoro et al.   Cell Metabolism

Transendothelial Insulin Transport is Impaired in Skeletal Muscle Capillaries of Obese Male Mice

(2020) Ian M. Williams et al.   Obesity

Transcriptomic profiling of skeletal muscle adaptations to exercise and inactivity

(2020) Nicolas J. Pillon et al.   Nature Communications

Cancer causes metabolic perturbations associated with reduced insulin-stimulated glucose uptake in peripheral tissues and impaired muscle microvascular perfusion

(2020) Xiuqing Han et al.   METABOLISM-CLINICAL AND EXPERIMENTAL

Intracellular calcium leak lowers glucose storage in human muscle, promoting hyperglycemia and diabetes

(2020) Eshwar R Tammineni et al.   eLife

Skeletal Muscle Extracellular Matrix – What Do We Know About Its Composition, Regulation, and Physiological Roles? A Narrative Review

(2020) Robert Csapo et al.   Frontiers in Physiology

Collagen 24 α1 Is Increased in Insulin-Resistant Skeletal Muscle and Adipose Tissue

(2020) Xiong Weng et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

CrossTalk proposal: Intramuscular lipid accumulation causes insulin resistance

(2020) Bret H. Goodpaster   JOURNAL OF PHYSIOLOGY-LONDON

A Cell-Autonomous Signature of Dysregulated Protein Phosphorylation Underlies Muscle Insulin Resistance in Type 2 Diabetes

(2020) Thiago M. Batista et al.   Cell Metabolism

The RabGAPs TBC1D1 and TBC1D4 Control Uptake of Long-Chain Fatty Acids Into Skeletal Muscle via Fatty Acid Transporter SLC27A4/FATP4

(2020) Tim Benninghoff et al.   DIABETES

The insulin‐sensitizing effect of a single exercise bout is similar in type I and type II human muscle fibres

(2020) Magnus R. Larsen et al.   JOURNAL OF PHYSIOLOGY-LONDON

Insulin‐stimulated glucose uptake partly relies on p21‐activated kinase (PAK)2, but not PAK1, in mouse skeletal muscle

(2020) Lisbeth L. V. Møller et al.   JOURNAL OF PHYSIOLOGY-LONDON

Tuning fatty acid oxidation in skeletal muscle with dietary fat and exercise

(2020) Andreas Mæchel Fritzen et al.   Nature Reviews Endocrinology

Effects of Diet versus Gastric Bypass on Metabolic Function in Diabetes

(2020) Mihoko Yoshino et al.   NEW ENGLAND JOURNAL OF MEDICINE

Prior exercise in humans redistributes intramuscular GLUT4 and enhances insulin-stimulated sarcolemmal and endosomal GLUT4 translocation

(2020) Jonas R. Knudsen et al.   Molecular Metabolism

Insulin-promoted mobilization of GLUT4 from a perinuclear storage site requires RAB10

(2020) Alexandria Brumfield et al.   MOLECULAR BIOLOGY OF THE CELL

β-catenin regulates muscle glucose transport via actin remodelling and M-cadherin binding

(2020) Stewart W.C. Masson et al.   Molecular Metabolism

Ceramides in Metabolism: Key Lipotoxic Players

(2020) Bhagirath Chaurasia et al.   Annual Review of Physiology

Intermuscular adipose tissue (IMAT) directly modulates skeletal muscle insulin sensitivity in humans

(2019) Stephan Sachs et al.   AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM

ADAMTS9 Regulates Skeletal Muscle Insulin Sensitivity Through Extracellular Matrix Alterations

(2019) Anne-Sofie Graae et al.   DIABETES

The effect of type 2 diabetes mellitus and obesity on muscle progenitor cell function

(2019) Shuzhi Teng et al.   Stem Cell Research & Therapy

Electroporated GLUT4-7myc -GFP detects in vivo glucose transporter 4 translocation in skeletal muscle without discernible changes in GFP patterns

(2019) Jonas Roland Knudsen et al.   EXPERIMENTAL PHYSIOLOGY

Skeletal Muscle Fiber Type-selective Effects of Acute Exercise on Insulin-stimulated Glucose Uptake in Insulin Resistant, High Fat-fed Rats

(2019) Mark W Pataky et al.   AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM

Rho GTPases—Emerging Regulators of Glucose Homeostasis and Metabolic Health

(2019) Møller et al.   Cells

TBC1D4 is Necessary for Enhancing Muscle Insulin Sensitivity in Response to AICAR and Contraction

(2019) Rasmus Kjøbsted et al.   DIABETES

Thirty sweet years of GLUT4

(2019) Amira Klip et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Perfusion Controls Muscle Glucose Uptake by Altering the Rate of Glucose Dispersion In Vivo

(2019) P. Mason McClatchey et al.   AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM

Fiber Type-specific Effects of Acute Exercise on Insulin-stimulated AS160 Phosphorylation in Insulin-Resistant Rat Skeletal Muscle

(2019) Mark W. Pataky et al.   AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM

Mechanisms involved in follistatin‐induced hypertrophy and increased insulin action in skeletal muscle

(2019) Xiuqing Han et al.   Journal of Cachexia Sarcopenia and Muscle

Insulin‐induced membrane permeability to glucose in human muscles at rest and following exercise

(2019) Glenn K. McConell et al.   JOURNAL OF PHYSIOLOGY-LONDON

Insulin uptake and action in microvascular endothelial cells of lymphatic and blood origin

(2018) Javier R. Jaldin-Fincati et al.   AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM

β-Actin shows limited mobility and is required only for supraphysiological insulin-stimulated glucose transport in young adult soleus muscle

(2018) Agnete B. Madsen et al.   AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM

The cell biology of systemic insulin function

(2018) Victoria L. Tokarz et al.   JOURNAL OF CELL BIOLOGY

Insulin exits skeletal muscle capillaries by fluid-phase transport

(2018) Ian M. Williams et al.   JOURNAL OF CLINICAL INVESTIGATION

Sphingolipid changes do not underlie fatty acid-evoked GLUT4 insulin resistance nor inflammation signals in muscle cells

(2018) Nicolas J. Pillon et al.   JOURNAL OF LIPID RESEARCH

Rac1 muscle knockout exacerbates the detrimental effect of high-fat diet on insulin-stimulated muscle glucose uptake independently of Akt

(2018) Steffen H. Raun et al.   JOURNAL OF PHYSIOLOGY-LONDON

GeneXX: an online tool for the exploration of transcript changes in skeletal muscle associated with exercise

(2018) Saskia Reibe et al.   PHYSIOLOGICAL GENOMICS

Mechanisms Preserving Insulin Action during High Dietary Fat Intake

(2018) Anne-Marie Lundsgaard et al.   Cell Metabolism

Muscle and adipose tissue insulin resistance: malady without mechanism?

(2018) Daniel J. Fazakerley et al.   JOURNAL OF LIPID RESEARCH

Mechanisms of Insulin Action and Insulin Resistance

(2018) Max C. Petersen et al.   PHYSIOLOGICAL REVIEWS

Exercise-induced molecular mechanisms promoting glycogen supercompensation in human skeletal muscle

(2018) Janne R. Hingst et al.   Molecular Metabolism

Exercise training reduces the insulin-sensitizing effect of a single bout of exercise in human skeletal muscle

(2018) Dorte E. Steenberg et al.   JOURNAL OF PHYSIOLOGY-LONDON

Metabolomic analysis of insulin resistance across different mouse strains and diets

(2017) Jacqueline Stöckli et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Skeletal muscle inflammation and insulin resistance in obesity

(2017) Huaizhu Wu et al.   JOURNAL OF CLINICAL INVESTIGATION

Inflammatory mechanisms linking obesity and metabolic disease

(2017) Alan R. Saltiel et al.   JOURNAL OF CLINICAL INVESTIGATION

Insulin action and resistance in obesity and type 2 diabetes

(2017) Michael P Czech   NATURE MEDICINE

Endothelial insulin receptors differentially control insulin signaling kinetics in peripheral tissues and brain of mice

(2017) Masahiro Konishi et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Update on GLUT4 Vesicle Traffic: A Cornerstone of Insulin Action

(2017) Javier R. Jaldin-Fincati et al.   TRENDS IN ENDOCRINOLOGY AND METABOLISM

Skeletal Muscle TRIB3 Mediates Glucose Toxicity in Diabetes and High- Fat Diet–Induced Insulin Resistance

(2016) Wei Zhang et al.   DIABETES

One Week of Bed Rest Leads to Substantial Muscle Atrophy and Induces Whole-Body Insulin Resistance in the Absence of Skeletal Muscle Lipid Accumulation

(2016) Marlou L. Dirks et al.   DIABETES

Enhanced Muscle Insulin Sensitivity After Contraction/Exercise Is Mediated by AMPK

(2016) Rasmus Kjøbsted et al.   DIABETES

A Role for Ceramides, but Not Sphingomyelins, as Antagonists of Insulin Signaling and Mitochondrial Metabolism in C2C12 Myotubes

(2016) Min Park et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Insulin and IGF-1 receptors regulate FoxO-mediated signaling in muscle proteostasis

(2016) Brian T. O’Neill et al.   JOURNAL OF CLINICAL INVESTIGATION

A human model of dietary saturated fatty acid induced insulin resistance

(2016) Juraj Koska et al.   METABOLISM-CLINICAL AND EXPERIMENTAL

A complex of Rab13 with MICAL-L2 and α-actinin-4 is essential for insulin-dependent GLUT4 exocytosis

(2016) Yi Sun et al.   MOLECULAR BIOLOGY OF THE CELL

Exercise-stimulated glucose uptake — regulation and implications for glycaemic control

(2016) Lykke Sylow et al.   Nature Reviews Endocrinology

Globular adiponectin controls insulin-mediated vasoreactivity in muscle through AMPKα2

(2016) Michiel P. de Boer et al.   VASCULAR PHARMACOLOGY

Enhanced insulin signaling in human skeletal muscle and adipose tissue following gastric bypass surgery

(2015) Peter H. Albers et al.   AMERICAN JOURNAL OF PHYSIOLOGY-REGULATORY INTEGRATIVE AND COMPARATIVE PHYSIOLOGY

Role of insulin in the regulation of human skeletal muscle protein synthesis and breakdown: a systematic review and meta-analysis

(2015) Haitham Abdulla et al.   DIABETOLOGIA

Fatty acid transport and transporters in muscle are critically regulated by Akt2

(2015) Swati S. Jain et al.   FEBS LETTERS

Intermuscular and perimuscular fat expansion in obesity correlates with skeletal muscle T cell and macrophage infiltration and insulin resistance

(2015) I M Khan et al.   INTERNATIONAL JOURNAL OF OBESITY

Clathrin-dependent entry and vesicle-mediated exocytosis define insulin transcytosis across microvascular endothelial cells

(2015) Paymon M. Azizi et al.   MOLECULAR BIOLOGY OF THE CELL

An Actin Filament Population Defined by the Tropomyosin Tpm3.1 Regulates Glucose Uptake

(2015) Anthony J. Kee et al.   TRAFFIC

Signaling of the p21-activated kinase (PAK1) coordinates insulin-stimulated actin remodeling and glucose uptake in skeletal muscle cells

(2014) Ragadeepthi Tunduguru et al.   BIOCHEMICAL PHARMACOLOGY

Calcium signaling in insulin action on striated muscle

(2014) A. Contreras-Ferrat et al.   CELL CALCIUM

Compartmentalized Acyl-CoA Metabolism in Skeletal Muscle Regulates Systemic Glucose Homeostasis

(2014) Lei O. Li et al.   DIABETES

Human Muscle Fiber Type–Specific Insulin Signaling: Impact of Obesity and Type 2 Diabetes

(2014) Peter H. Albers et al.   DIABETES

Lipid-Induced Insulin Resistance Is Associated With an Impaired Skeletal Muscle Protein Synthetic Response to Amino Acid Ingestion in Healthy Young Men

(2014) Francis B. Stephens et al.   DIABETES

Roles of TBC1D1 and TBC1D4 in insulin- and exercise-stimulated glucose transport of skeletal muscle

(2014) Gregory D. Cartee   DIABETOLOGIA

Insulin elicits a ROS-activated and an IP3-dependent Ca2+ release, which both impinge on GLUT4 translocation

(2014) A. Contreras-Ferrat et al.   JOURNAL OF CELL SCIENCE

Insulin diffusion and self-association characterized by real-time UV imaging and Taylor dispersion analysis

(2014) Sabrine S. Jensen et al.   JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS

Myosin Va mediates Rab8A-regulated GLUT4 vesicle exocytosis in insulin-stimulated muscle cells

(2014) Yi Sun et al.   MOLECULAR BIOLOGY OF THE CELL

A common Greenlandic TBC1D4 variant confers muscle insulin resistance and type 2 diabetes

(2014) Ida Moltke et al.   NATURE

Identification and characterization of PDGFRα+ mesenchymal progenitors in human skeletal muscle

(2014) A Uezumi et al.   Cell Death & Disease

Dynamic GLUT4 sorting through a syntaxin-6 compartment in muscle cells is derailed by insulin resistance-causing ceramide

(2014) K. P. Foley et al.   Biology Open

Akt and Rac1 signaling are jointly required for insulin-stimulated glucose uptake in skeletal muscle and downregulated in insulin resistance

(2013) Lykke Sylow et al.   CELLULAR SIGNALLING

Rac1 Signaling Is Required for Insulin-Stimulated Glucose Uptake and Is Dysregulated in Insulin-Resistant Murine and Human Skeletal Muscle

(2013) L. Sylow et al.   DIABETES

Early Enhancements of Hepatic and Later of Peripheral Insulin Sensitivity Combined With Increased Postprandial Insulin Secretion Contribute to Improved Glycemic Control After Roux-en-Y Gastric Bypass

(2013) Kirstine N. Bojsen-Møller et al.   DIABETES

Expression of anti-inflammatory macrophage genes within skeletal muscle correlates with insulin sensitivity in human obesity and type 2 diabetes

(2013) L. N. Fink et al.   DIABETOLOGIA

Impaired Akt phosphorylation in insulin-resistant human muscle is accompanied by selective and heterogeneous downstream defects

(2013) K. T. Tonks et al.   DIABETOLOGIA

Slow-Twitch Fiber Proportion in Skeletal Muscle Correlates With Insulin Responsiveness

(2013) Charles A. Stuart et al.   JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM

Physical inactivity affects skeletal muscle insulin signaling in a birth weight-dependent manner

(2013) Brynjulf Mortensen et al.   JOURNAL OF DIABETES AND ITS COMPLICATIONS

Acute exercise and physiological insulin induce distinct phosphorylation signatures on TBC1D1 and TBC1D4 proteins in human skeletal muscle

(2013) Jonas T. Treebak et al.   JOURNAL OF PHYSIOLOGY-LONDON

Endothelial Cells Actively Concentrate Insulin During its Transendothelial Transport

(2013) Amanda J. Genders et al.   MICROCIRCULATION

Pro-Inflammatory macrophages increase in skeletal muscle of high fat-Fed mice and correlate with metabolic risk markers in humans

(2013) Lisbeth N. Fink et al.   Obesity

Exercise, GLUT4, and Skeletal Muscle Glucose Uptake

(2013) Erik A. Richter et al.   PHYSIOLOGICAL REVIEWS

Opening of the mitochondrial permeability transition pore links mitochondrial dysfunction to insulin resistance in skeletal muscle

(2013) E.P. Taddeo et al.   Molecular Metabolism

Insulin stimulates fusion, but not tethering, of GLUT4 vesicles in skeletal muscle of HA-GLUT4-GFP transgenic mice

(2012) Vladimir A. Lizunov et al.   AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM

Insulin Activation of Plasma Nonesterified Fatty Acid Uptake in Metabolic Syndrome

(2012) Maria A. Ramos-Roman et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Glycogen and its metabolism: some new developments and old themes

(2012) Peter J. Roach et al.   BIOCHEMICAL JOURNAL

AS160 deficiency causes whole-body insulin resistance via composite effects in multiple tissues

(2012) Hong Yu Wang et al.   BIOCHEMICAL JOURNAL

Muscle cells challenged with saturated fatty acids mount an autonomous inflammatory response that activates macrophages

(2012) Nicolas J Pillon et al.   Cell Communication and Signaling

Altered Response of Skeletal Muscle to IL-6 in Type 2 Diabetic Patients

(2012) L. Q. Jiang et al.   DIABETES

Exercise Alleviates Lipid-Induced Insulin Resistance in Human Skeletal Muscle-Signaling Interaction at the Level of TBC1 Domain Family Member 4

(2012) C. Pehmoller et al.   DIABETES

Regulation of insulin sensitivity by serine/threonine phosphorylation of insulin receptor substrate proteins IRS1 and IRS2

(2012) K. D. Copps et al.   DIABETOLOGIA

Insulin- and Contraction-Induced Glucose Transporter 4 Traffic in Muscle

(2012) Hans P.M.M. Lauritzen   EXERCISE AND SPORT SCIENCES REVIEWS

GLUT4 exocytosis

(2012) Jacqueline Stöckli et al.   JOURNAL OF CELL SCIENCE

Mitochondrial Oxidative Phosphorylation Is Impaired in Patients with Congenital Lipodystrophy

(2012) Alison Sleigh et al.   JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM

Myo1c binding to submembrane actin mediates insulin-induced tethering of GLUT4 vesicles

(2012) Shlomit Boguslavsky et al.   MOLECULAR BIOLOGY OF THE CELL

Insulin and insulin signaling play a critical role in fat induction of insulin resistance in mouse

(2011) Jie Ning et al.   AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM

A new method to study changes in microvascular blood volume in muscle and adipose tissue: real-time imaging in humans and rat

(2011) Kim A. Sjøberg et al.   AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY

Acute exercise activates AMPK and eNOS in the mouse aorta

(2011) José M. Cacicedo et al.   AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY

Diet-Induced Muscle Insulin Resistance Is Associated With Extracellular Matrix Remodeling and Interaction With Integrin  2 1 in Mice

(2011) L. Kang et al.   DIABETES

Fat-induced membrane cholesterol accrual provokes cortical filamentous actin destabilisation and glucose transport dysfunction in skeletal muscle

(2011) K. M. Habegger et al.   DIABETOLOGIA

Low-volume high-intensity interval training reduces hyperglycemia and increases muscle mitochondrial capacity in patients with type 2 diabetes

(2011) Jonathan P. Little et al.   JOURNAL OF APPLIED PHYSIOLOGY

Inhibition or Ablation of p21-activated Kinase (PAK1) Disrupts Glucose Homeostatic Mechanismsin Vivo

(2011) Zhanxiang Wang et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Three Weeks on a High-Fat Diet Increases Intrahepatic Lipid Accumulation and Decreases Metabolic Flexibility in Healthy Overweight Men

(2011) Noud A. van Herpen et al.   JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM

Mitochondrial dysfunction in patients with primary congenital insulin resistance

(2011) Alison Sleigh et al.   JOURNAL OF CLINICAL INVESTIGATION

Fiber Types in Mammalian Skeletal Muscles

(2011) Stefano Schiaffino et al.   PHYSIOLOGICAL REVIEWS

T-tubule biogenesis and triad formation in skeletal muscle and implication in human diseases

(2011) Lama Al-Qusairi et al.   Skeletal Muscle

Improved glucose tolerance after intensive life style intervention occurs without changes in muscle ceramide or triacylglycerol in morbidly obese subjects

(2010) J. W. Helge et al.   Acta Physiologica

Insulin resistance induced by physical inactivity is associated with multiple transcriptional changes in skeletal muscle in young men

(2010) A. C. Alibegovic et al.   AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM

An increase in essential amino acid availability upregulates amino acid transporter expression in human skeletal muscle

(2010) Micah J. Drummond et al.   AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM

Allosteric Regulation of Glycogen Synthase Controls Glycogen Synthesis in Muscle

(2010) Michale Bouskila et al.   Cell Metabolism

Biogenesis and regulation of insulin-responsive vesicles containing GLUT4

(2010) Jonathan S Bogan et al.   CURRENT OPINION IN CELL BIOLOGY

Lipid-Induced Insulin Resistance Affects Women Less Than Men and Is Not Accompanied by Inflammation or Impaired Proximal Insulin Signaling

(2010) L. D. Hoeg et al.   DIABETES

Impaired insulin-induced site-specific phosphorylation of TBC1 domain family, member 4 (TBC1D4) in skeletal muscle of type 2 diabetes patients is restored by endurance exercise-training

(2010) B. F. Vind et al.   DIABETOLOGIA

Crucial role of the small GTPase Rac1 in insulin-stimulated translocation of glucose transporter 4 to the mouse skeletal muscle sarcolemma

(2010) Shuji Ueda et al.   FASEB JOURNAL

The clathrin heavy chain isoform CHC22 functions in a novel endosomal sorting step

(2010) Christopher Esk et al.   JOURNAL OF CELL BIOLOGY

Distinct growth hormone receptor signaling modes regulate skeletal muscle development and insulin sensitivity in mice

(2010) Mahendra D. Mavalli et al.   JOURNAL OF CLINICAL INVESTIGATION

Arp2/3- and Cofilin-coordinated Actin Dynamics Is Required for Insulin-mediated GLUT4 Translocation to the Surface of Muscle Cells

(2010) Tim Ting Chiu et al.   MOLECULAR BIOLOGY OF THE CELL

Rab8A and Rab13 are activated by insulin and regulate GLUT4 translocation in muscle cells

(2010) Y. Sun et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Effects of 7 days of exercise training on insulin sensitivity and responsiveness in type 2 diabetes mellitus

(2009) John P. Kirwan et al.   AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM

In vivo imaging of GLUT4 translocationThis paper is one of a selection of papers published in this Special Issue, entitled 14th International Biochemistry of Exercise Conference – Muscles as Molecular and Metabolic Machines, and has undergone the Journal’s usual peer review process.

(2009) Hans P.M.M. Lauritzen   Applied Physiology Nutrition and Metabolism

GAPDH binds GLUT4 reciprocally to hexokinase-II and regulates glucose transport activity

(2009) Hilal Zaid et al.   BIOCHEMICAL JOURNAL

Insulin Resistance Is Associated With Higher Intramyocellular Triglycerides in Type I but Not Type II Myocytes Concomitant With Higher Ceramide Content

(2009) P. M. Coen et al.   DIABETES

Skeletal Muscle Insulin Resistance Is the Primary Defect in Type 2 Diabetes

(2009) R. A. DeFronzo et al.   DIABETES CARE

FoxO1 Controls Insulin-dependent Adipose Triglyceride Lipase (ATGL) Expression and Lipolysis in Adipocytes

(2009) Partha Chakrabarti et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Identification of a Distal GLUT4 Trafficking Event Controlled by Actin Polymerization

(2009) Jamie A. Lopez et al.   MOLECULAR BIOLOGY OF THE CELL

Activation of the small GTPase Rac1 by a specific guanine-nucleotide-exchange factor suffices to induce glucose uptake into skeletal-muscle cells

(2008) Shuji Ueda et al.   BIOLOGY OF THE CELL

Mitochondrial Overload and Incomplete Fatty Acid Oxidation Contribute to Skeletal Muscle Insulin Resistance

(2008) Timothy R. Koves et al.   Cell Metabolism

siRNA-Mediated Reduction of Inhibitor of Nuclear Factor- B Kinase Prevents Tumor Necrosis Factor- -Induced Insulin Resistance in Human Skeletal Muscle

(2008) R. L. Austin et al.   DIABETES

Human skeletal muscle ceramide content is not a major factor in muscle insulin sensitivity

(2008) M. Skovbro et al.   DIABETOLOGIA

A Transgenic Mouse Model to Study Glucose Transporter 4mycRegulation in Skeletal Muscle

(2008) Jonathan D. Schertzer et al.   ENDOCRINOLOGY

Insulin Resistance in Striated Muscle-specific Integrin Receptor β1-deficient Mice

(2008) Haihong Zong et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

In vivoinhibition of focal adhesion kinase causes insulin resistance

(2008) Bharti Bisht et al.   JOURNAL OF PHYSIOLOGY-LONDON

Tbc1d1 mutation in lean mouse strain confers leanness and protects from diet-induced obesity

(2008) Alexandra Chadt et al.   NATURE GENETICS

Insulin promotes glycogen synthesis in the absence of GSK3 phosphorylation in skeletal muscle

(2007) Michale Bouskila et al.   AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM