Exercise, GLUT4, and Skeletal Muscle Glucose Uptake

LKB1 Regulates Lipid Oxidation During Exercise Independently of AMPK

(2013) J. Jeppesen et al.   DIABETES

Thr649Ala-AS160 knock-in mutation does not impair contraction/AICAR-induced glucose transport in mouse muscle

(2012) Serge Ducommun et al.   AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM

Rac1 Is a Novel Regulator of Contraction-Stimulated Glucose Uptake in Skeletal Muscle

(2012) L. Sylow et al.   DIABETES

Physiological adaptations to low-volume, high-intensity interval training in health and disease

(2012) Martin J. Gibala et al.   JOURNAL OF PHYSIOLOGY-LONDON

A new method to study changes in microvascular blood volume in muscle and adipose tissue: real-time imaging in humans and rat

(2011) Kim A. Sjøberg et al.   AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY

Endocytosis, Recycling, and Regulated Exocytosis of Glucose Transporter 4

(2011) Kevin Foley et al.   BIOCHEMISTRY

TBC proteins: GAPs for mammalian small GTPase Rab?

(2011) Mitsunori Fukuda   BIOSCIENCE REPORTS

Mice with AS160/TBC1D4-Thr649Ala Knockin Mutation Are Glucose Intolerant with Reduced Insulin Sensitivity and Altered GLUT4 Trafficking

(2011) Shuai Chen et al.   Cell Metabolism

Rac1 signalling towards GLUT4/glucose uptake in skeletal muscle

(2011) Tim T. Chiu et al.   CELLULAR SIGNALLING

AMPKα2 deficiency uncovers time dependency in the regulation of contraction-induced palmitate and glucose uptake in mouse muscle

(2011) Marcia J. Abbott et al.   JOURNAL OF APPLIED PHYSIOLOGY

Clustering of GLUT4, TUG, and RUVBL2 protein levels correlate with myosin heavy chain isoform pattern in skeletal muscles, but AS160 and TBC1D1 levels do not

(2011) Carlos M. Castorena et al.   JOURNAL OF APPLIED PHYSIOLOGY

AMP-activated protein kinase (AMPK)  1 2 muscle null mice reveal an essential role for AMPK in maintaining mitochondrial content and glucose uptake during exercise

(2011) H. M. O'Neill et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

AMPK Is a Direct Adenylate Charge-Regulated Protein Kinase

(2011) J. S. Oakhill et al.   SCIENCE

Caffeine activates preferentially α1-isoform of 5′AMP-activated protein kinase in rat skeletal muscle

(2010) T. Egawa et al.   Acta Physiologica

CaMKII regulates contraction- but not insulin-induced glucose uptake in mouse skeletal muscle

(2010) Carol A. Witczak et al.   AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM

Contraction regulates site-specific phosphorylation of TBC1D1 in skeletal muscle

(2010) Kanokwan Vichaiwong et al.   BIOCHEMICAL JOURNAL

Kinetics of Contraction-Induced GLUT4 Translocation in Skeletal Muscle Fibers From Living Mice

(2010) H. P. M. M. Lauritzen et al.   DIABETES

TBC1D1 Regulates Insulin- and Contraction-Induced Glucose Transport in Mouse Skeletal Muscle

(2010) D. An et al.   DIABETES

Crucial role of the small GTPase Rac1 in insulin-stimulated translocation of glucose transporter 4 to the mouse skeletal muscle sarcolemma

(2010) Shuji Ueda et al.   FASEB JOURNAL

Local hindlimb antioxidant infusion does not affect muscle glucose uptake during in situ contractions in rat

(2010) T. L. Merry et al.   JOURNAL OF APPLIED PHYSIOLOGY

Myo1c Regulates Glucose Uptake in Mouse Skeletal Muscle

(2010) Taro Toyoda et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Exercise-induced TBC1D1 Ser237 phosphorylation and 14-3-3 protein binding capacity in human skeletal muscle

(2010) Christian Frøsig et al.   JOURNAL OF PHYSIOLOGY-LONDON

N-Acetylcysteine infusion does not affect glucose disposal during prolonged moderate-intensity exercise in humans

(2010) Troy L. Merry et al.   JOURNAL OF PHYSIOLOGY-LONDON

Sucrose nonfermenting AMPK-related kinase (SNARK) mediates contraction-stimulated glucose transport in mouse skeletal muscle

(2010) H.-J. Koh et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Rab8A and Rab13 are activated by insulin and regulate GLUT4 translocation in muscle cells

(2010) Y. Sun et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The Role of JNK Proteins in Metabolism

(2010) S. N. Vallerie et al.   Science Translational Medicine

ATP consumption by sarcoplasmic reticulum Ca2+ pumps accounts for 50% of resting metabolic rate in mouse fast and slow twitch skeletal muscle

(2009) Sarah Michelle Norris et al.   AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY

Reduced malonyl-CoA content in recovery from exercise correlates with improved insulin-stimulated glucose uptake in human skeletal muscle

(2009) Christian Frøsig et al.   AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM

Knockout of the predominant conventional PKC isoform, PKCα, in mouse skeletal muscle does not affect contraction-stimulated glucose uptake

(2009) Thomas E. Jensen et al.   AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM

Increased AS160 phosphorylation, but not TBC1D1 phosphorylation, with increased postexercise insulin sensitivity in rat skeletal muscle

(2009) Katsuhiko Funai et al.   AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM

Genetic disruption of AMPK signaling abolishes both contraction- and insulin-stimulated TBC1D1 phosphorylation and 14-3-3 binding in mouse skeletal muscle

(2009) Christian Pehmøller et al.   AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM

Genetic impairment of AMPKα2 signaling does not reduce muscle glucose uptake during treadmill exercise in mice

(2009) Stine J. Maarbjerg et al.   AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM

Skeletal muscle glucose uptake during contraction is regulated by nitric oxide and ROS independently of AMPK

(2009) Troy L. Merry et al.   AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM

AICAR and metformin, but not exercise, increase muscle glucose transport through AMPK-, ERK-, and PDK1-dependent activation of atypical PKC

(2009) M. P. Sajan et al.   AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM

Regulation of GLUT4 expression in denervated skeletal muscle

(2009) Ellis B. Jensen et al.   AMERICAN JOURNAL OF PHYSIOLOGY-REGULATORY INTEGRATIVE AND COMPARATIVE PHYSIOLOGY

CaMKK is an upstream signal of AMP-activated protein kinase in regulation of substrate metabolism in contracting skeletal muscle

(2009) Marcia J. Abbott et al.   AMERICAN JOURNAL OF PHYSIOLOGY-REGULATORY INTEGRATIVE AND COMPARATIVE PHYSIOLOGY

Effects of contraction on localization of GLUT4 and v-SNARE isoforms in rat skeletal muscle

(2009) Adam J. Rose et al.   AMERICAN JOURNAL OF PHYSIOLOGY-REGULATORY INTEGRATIVE AND COMPARATIVE PHYSIOLOGY

The many ways to regulate glucose transporter 4This paper is one of a selection of papers published in this Special Issue, entitled 14th International Biochemistry of Exercise Conference – Muscles as Molecular and Metabolic Machines, and has undergone the Journal’s usual peer review process.

(2009) Amira Klip   Applied Physiology Nutrition and Metabolism

GAPDH binds GLUT4 reciprocally to hexokinase-II and regulates glucose transport activity

(2009) Hilal Zaid et al.   BIOCHEMICAL JOURNAL

Kinetics of GLUT4 Trafficking in Rat and Human Skeletal Muscle

(2009) H. K.R. Karlsson et al.   DIABETES

Inhibition of Contraction-Stimulated AMP-Activated Protein Kinase Inhibits Contraction-Stimulated Increases in PAS-TBC1D1 and Glucose Transport Without Altering PAS-AS160 in Rat Skeletal Muscle

(2009) K. Funai et al.   DIABETES

Kinetic Evidence for Unique Regulation of GLUT4 Trafficking by Insulin and AMP-activated Protein Kinase Activators in L6 Myotubes

(2009) Daniel J. Fazakerley et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Skeletal Muscle AMP-activated Protein Kinase Is Essential for the Metabolic Response to Exercisein Vivo

(2009) Robert S. Lee-Young et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Multiple signalling pathways redundantly control glucose transporterGLUT4gene transcription in skeletal muscle

(2009) Marta Murgia et al.   JOURNAL OF PHYSIOLOGY-LONDON

Exercise-induced histone modifications in human skeletal muscle

(2009) Sean L. McGee et al.   JOURNAL OF PHYSIOLOGY-LONDON

Endurance exercise induces mRNA expression of oxidative enzymes in human skeletal muscle late in recovery

(2009) L. Leick et al.   SCANDINAVIAN JOURNAL OF MEDICINE & SCIENCE IN SPORTS

Muscle cells engage Rab8A and myosin Vb in insulin-dependent GLUT4 translocation

(2008) Shuhei Ishikura et al.   AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY

Caffeine induces hyperacetylation of histones at the MEF2 site on the Glut4 promoter and increases MEF2A binding to the site via a CaMK-dependent mechanism

(2008) Emmanuel Mukwevho et al.   AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM

CaMK activation during exercise is required for histone hyperacetylation and MEF2A binding at the MEF2 site on the Glut4 gene

(2008) James A. H. Smith et al.   AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM

The α-subunit of AMPK is essential for submaximal contraction-mediated glucose transport in skeletal muscle in vitro

(2008) Natalie Lefort et al.   AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM

Four grams of glucose

(2008) David H. Wasserman   AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM

Metabolic, enzymatic, and transporter responses in human muscle during three consecutive days of exercise and recovery

(2008) Howard J. Green et al.   AMERICAN JOURNAL OF PHYSIOLOGY-REGULATORY INTEGRATIVE AND COMPARATIVE PHYSIOLOGY

Complementary regulation of TBC1D1 and AS160 by growth factors, insulin and AMPK activators

(2008) Shuai Chen et al.   BIOCHEMICAL JOURNAL

Activation of the small GTPase Rac1 by a specific guanine-nucleotide-exchange factor suffices to induce glucose uptake into skeletal-muscle cells

(2008) Shuji Ueda et al.   BIOLOGY OF THE CELL

AMP-Activated Protein Kinase Regulates GLUT4 Transcription by Phosphorylating Histone Deacetylase 5

(2008) S. L. McGee et al.   DIABETES

Contraction-stimulated glucose transport in rat skeletal muscle is sustained despite reversal of increased PAS-phosphorylation of AS160 and TBC1D1

(2008) Katsuhiko Funai et al.   JOURNAL OF APPLIED PHYSIOLOGY

Evidence for the involvement of CaMKII and AMPK in Ca2+-dependent signaling pathways regulating FA uptake and oxidation in contracting rodent muscle

(2008) Marcella A. Raney et al.   JOURNAL OF APPLIED PHYSIOLOGY

Discovery of TBC1D1 as an Insulin-, AICAR-, and Contraction-stimulated Signaling Nexus in Mouse Skeletal Muscle

(2008) Eric B. Taylor et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Histone Deacetylase 5 Acquires Calcium/Calmodulin-Dependent Kinase II Responsiveness by Oligomerization with Histone Deacetylase 4

(2008) J. Backs et al.   MOLECULAR AND CELLULAR BIOLOGY

AMPK α1 Activation Is Required for Stimulation of Glucose Uptake by Twitch Contraction, but Not by H2O2, in Mouse Skeletal Muscle

(2008) Thomas E. Jensen et al.   PLoS One

Clathrin-Dependent and Independent Endocytosis of Glucose Transporter 4 (GLUT4) in Myoblasts: Regulation by Mitochondrial Uncoupling

(2008) Costin N. Antonescu et al.   TRAFFIC

Free radicals and muscle fatigue: Of ROS, canaries, and the IOC

(2007) Michael B. Reid   FREE RADICAL BIOLOGY AND MEDICINE