Inhibition or Ablation of p21-activated Kinase (PAK1) Disrupts Glucose Homeostatic Mechanismsin Vivo

p21-activated kinase 1: PAK’ed with potential

(2015) Christy Ong et al.   Oncotarget

Rac1 signalling towards GLUT4/glucose uptake in skeletal muscle

(2011) Tim T. Chiu et al.   CELLULAR SIGNALLING

Focal Adhesion Remodeling Is Crucial for Glucose-Stimulated Insulin Secretion and Involves Activation of Focal Adhesion Kinase and Paxillin

(2011) D. Rondas et al.   DIABETES

Targeting p21-activated kinase 1 (PAK1) to induce apoptosis of tumor cells

(2011) C. C. Ong et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Protein Farnesylation-Dependent Raf/Extracellular Signal-Related Kinase Signaling Links to Cytoskeletal Remodeling to Facilitate Glucose-Induced Insulin Secretion in Pancreatic  -Cells

(2010) A. Kowluru et al.   DIABETES

Crucial role of the small GTPase Rac1 in insulin-stimulated translocation of glucose transporter 4 to the mouse skeletal muscle sarcolemma

(2010) Shuji Ueda et al.   FASEB JOURNAL

The unique hypusine modification of eIF5A promotes islet β cell inflammation and dysfunction in mice

(2010) Bernhard Maier et al.   JOURNAL OF CLINICAL INVESTIGATION

Arp2/3- and Cofilin-coordinated Actin Dynamics Is Required for Insulin-mediated GLUT4 Translocation to the Surface of Muscle Cells

(2010) Tim Ting Chiu et al.   MOLECULAR BIOLOGY OF THE CELL

Small-molecule p21-activated kinase inhibitor PF-3758309 is a potent inhibitor of oncogenic signaling and tumor growth

(2010) B. W. Murray et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

p21-activated kinase regulates mast cell degranulation via effects on calcium mobilization and cytoskeletal dynamics

(2009) J. D. Allen et al.   BLOOD

Munc18c Depletion Selectively Impairs the Sustained Phase of Insulin Release

(2009) E. Oh et al.   DIABETES

Regulation of insulin secretion: a matter of phase control and amplitude modulation

(2009) J. C. Henquin   DIABETOLOGIA

Diacylglycerol Kinase ζ Regulates Actin Cytoskeleton Reorganization through Dissociation of Rac1 from RhoGDI

(2009) Hanan Abramovici et al.   MOLECULAR BIOLOGY OF THE CELL

P-21-activated protein kinase-1 functions as a linker between insulin and Wnt signaling pathways in the intestine

(2009) J Sun et al.   ONCOGENE

Regulation of cardiac excitation and contraction by p21 activated kinase-1

(2009) Yunbo Ke et al.   PROGRESS IN BIOPHYSICS & MOLECULAR BIOLOGY

A tale of two Paks

(2008) Luis E. Arias-Romero et al.   BIOLOGY OF THE CELL

An Isoform-Selective, Small-Molecule Inhibitor Targets the Autoregulatory Mechanism of p21-Activated Kinase

(2008) Sean W. Deacon et al.   CHEMISTRY & BIOLOGY

A gene expression network model of type 2 diabetes links cell cycle regulation in islets with diabetes susceptibility

(2008) M. P. Keller et al.   GENOME RESEARCH

PAK1-mediated activation of ERK1/2 regulates lamellipodial dynamics

(2008) S. D. Smith et al.   JOURNAL OF CELL SCIENCE

Pak1 and Pak2 Mediate Tumor Cell Invasion through Distinct Signaling Mechanisms

(2008) S. J. Coniglio et al.   MOLECULAR AND CELLULAR BIOLOGY

Regulation of hippocampal long-term potentiation by p21-activated protein kinase 1 (PAK1)

(2008) Suhail Asrar et al.   NEUROPHARMACOLOGY