TLR2- and TLR3-activated microglia induce different levels of neuronal network dysfunction in a context-dependent manner

Selective inhibition of mitochondrial respiratory complexes controls the transition of microglia into a neurotoxic phenotype in situ

(2020) Bruno Chausse et al.   BRAIN BEHAVIOR AND IMMUNITY

GM-CSF induces noninflammatory proliferation of microglia and disturbs electrical neuronal network rhythms in situ

(2020) Hasan Onur Dikmen et al.   Journal of Neuroinflammation

Neuronal gamma oscillations and activity‐dependent potassium transients remain regular after depletion of microglia in postnatal cortex tissue

(2020) Andrea Lewen et al.   JOURNAL OF NEUROSCIENCE RESEARCH

Brain energy rescue: an emerging therapeutic concept for neurodegenerative disorders of ageing

(2020) Stephen C. Cunnane et al.   NATURE REVIEWS DRUG DISCOVERY

Parvalbumin and Somatostatin Interneurons Contribute to the Generation of Hippocampal Gamma Oscillations

(2020) Pantelis Antonoudiou et al.   JOURNAL OF NEUROSCIENCE

Microglia and lipids: how metabolism controls brain innate immunity

(2020) Bruno Chausse et al.   SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY

Priming of microglia with IFN-γ slows neuronal gamma oscillations in situ

(2019) Thuy-Truc Ta et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Innate Immune Signaling Organelles Display Natural and Programmable Signaling Flexibility

(2019) Yunhao Tan et al.   CELL

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(2019) Willem J. M. Mulder et al.   NATURE REVIEWS DRUG DISCOVERY

Inhibition of NADPH oxidase by apocynin prevents learning and memory deficits in a mouse Parkinson's disease model

(2019) Liyan Hou et al.   Redox Biology

Single-cell analysis reveals T cell infiltration in old neurogenic niches

(2019) Ben W. Dulken et al.   NATURE

Microglia and sexual differentiation of the developing brain: A focus on ontogeny and intrinsic factors

(2019) Evan A. Bordt et al.   GLIA

Mild metabolic stress is sufficient to disturb the formation of pyramidal cell ensembles during gamma oscillations

(2019) Shehabeldin Elzoheiry et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

Antibiotic drug piperacillin induces neuron cell death through mitochondrial dysfunction and oxidative damage

(2018) Shan Jiang et al.   CANADIAN JOURNAL OF PHYSIOLOGY AND PHARMACOLOGY

Alzheimer’s Disease: From Firing Instability to Homeostasis Network Collapse

(2018) Samuel Frere et al.   NEURON

Sex-Specific Features of Microglia from Adult Mice

(2018) Alessandro Villa et al.   Cell Reports

Inflammasome signalling in brain function and neurodegenerative disease

(2018) Michael T. Heneka et al.   NATURE REVIEWS NEUROSCIENCE

Microglial dopamine receptor elimination defines sex-specific nucleus accumbens development and social behavior in adolescent rats

(2018) Ashley M. Kopec et al.   Nature Communications

GABAergic Interneurons in Seizures: Investigating Causality With Optogenetics

(2018) Vincent Magloire et al.   NEUROSCIENTIST

Role of Microglia TLRs in Neurodegeneration

(2018) Bernd L. Fiebich et al.   Frontiers in Cellular Neuroscience

Activation of EP2 receptor suppresses poly(I: C) and LPS-mediated inflammation in primary microglia and organotypic hippocampal slice cultures: Contributing role for MAPKs

(2017) Nizar M. Yousif et al.   GLIA

Toll like receptor 3 and viral infections of nervous system

(2017) Rajesh Verma et al.   JOURNAL OF THE NEUROLOGICAL SCIENCES

Chronoinflammaging in Alzheimer; A systematic review on the roles of toll like receptor 2

(2017) Ali Ravari et al.   LIFE SCIENCES

The role of peripheral immune cells in the CNS in steady state and disease

(2017) Marco Prinz et al.   NATURE NEUROSCIENCE

Distinct Inhibitory Circuits Orchestrate Cortical beta and gamma Band Oscillations

(2017) Guang Chen et al.   NEURON

The interneuron energy hypothesis: Implications for brain disease

(2016) Oliver Kann   NEUROBIOLOGY OF DISEASE

How neuroinflammation contributes to neurodegeneration

(2016) R. M. Ransohoff   SCIENCE

Neuroinflammatory changes negatively impact on LTP: A focus on IL-1β

(2015) Marina A Lynch   BRAIN RESEARCH

Electroencephalography for diagnosis and prognosis of acute encephalitis

(2015) Raoul Sutter et al.   CLINICAL NEUROPHYSIOLOGY

Activation of microglial Toll-like receptor 3 promotes neuronal survival against cerebral ischemia

(2015) Si-Yeon Jeong et al.   JOURNAL OF NEUROCHEMISTRY

Ligand engagement of Toll-like receptors regulates their expression in cortical microglia and astrocytes

(2015) Carla Marinelli et al.   Journal of Neuroinflammation

A reliable model for gamma oscillations in hippocampal tissue

(2015) Justus Schneider et al.   JOURNAL OF NEUROSCIENCE RESEARCH

TLR4-activated microglia require IFN-γ to induce severe neuronal dysfunction and death in situ

(2015) Ismini E. Papageorgiou et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

TLR2-induced astrocyte MMP9 activation compromises the blood brain barrier and exacerbates intracerebral hemorrhage in animal models

(2015) Hyunjung Min et al.   Molecular Brain

The impact of single and pairwise Toll-like receptor activation on neuroinflammation and neurodegeneration

(2014) Karen Rosenberger et al.   Journal of Neuroinflammation

Microglial CR3 Activation Triggers Long-Term Synaptic Depression in the Hippocampus via NADPH Oxidase

(2014) Jingfei Zhang et al.   NEURON

Microglial polarization and plasticity: Evidence from organotypic hippocampal slice cultures

(2013) Maria Antonietta Ajmone-Cat et al.   GLIA

Toll-like receptor 3 activation modulates hippocampal network excitability, via glial production of interferon-β

(2013) Derek A. Costello et al.   HIPPOCAMPUS

The impact of neuroimmune changes on development of amyloid pathology; relevance to Alzheimer's disease

(2013) Marina A. Lynch   IMMUNOLOGY

TLR3-Triggered Reactive Oxygen Species Contribute to Inflammatory Responses by Activating Signal Transducer and Activator of Transcription-1

(2013) C.-S. Yang et al.   JOURNAL OF IMMUNOLOGY

Microglia Are Essential to Masculinization of Brain and Behavior

(2013) K. M. Lenz et al.   JOURNAL OF NEUROSCIENCE

Knockout of Toll-like receptor 2 attenuates Aβ25–35-induced neurotoxicity in organotypic hippocampal slice cultures

(2013) Eun Cheng Suh et al.   NEUROCHEMISTRY INTERNATIONAL

Bioenergetic and Antiapoptotic Properties of Mitochondria from Cultured Human Prostate Cancer Cell Lines PC-3, DU145 and LNCaP

(2013) Alexander Panov et al.   PLoS One

Oxygen Consumption Rates during Three Different Neuronal Activity States in the Hippocampal CA3 Network

(2012) Christine Huchzermeyer et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

Neuroprotective function for ramified microglia in hippocampal excitotoxicity

(2012) Jonathan Vinet et al.   Journal of Neuroinflammation

IL-1 receptor/Toll-like receptor signaling in infection, inflammation, stress and neurodegeneration couples hyperexcitability and seizures

(2011) Annamaria Vezzani et al.   BRAIN BEHAVIOR AND IMMUNITY

Toll-like receptors in health and disease in the brain: mechanisms and therapeutic potential

(2011) Mark L. Hanke et al.   CLINICAL SCIENCE

Long Term Potentiation Is Impaired in Membrane Glycoprotein CD200-deficient Mice

(2011) Derek A. Costello et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Gamma oscillations in the hippocampus require high complex I gene expression and strong functional performance of mitochondria

(2010) Oliver Kann et al.   BRAIN

Peptidoglycan enhances proinflammatory cytokine expression through the TLR2 receptor, MyD88, phosphatidylinositol 3-kinase/AKT and NF-kappaB pathways in BV-2 microglia

(2010) Hsiao-Yun Lin et al.   INTERNATIONAL IMMUNOPHARMACOLOGY

Differential expression of interferon-γ receptor on human glial cells in vivo and in vitro

(2010) Sadayuki Hashioka et al.   JOURNAL OF NEUROIMMUNOLOGY

Activated Microglia Mediate Axoglial Disruption That Contributes to Axonal Injury in Multiple Sclerosis

(2010) Owain W. Howell et al.   JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY

Nitric oxide and neuronal death

(2010) Guy C. Brown   NITRIC OXIDE-BIOLOGY AND CHEMISTRY

Microglial Physiology: Unique Stimuli, Specialized Responses

(2009) Richard M. Ransohoff et al.   Annual Review of Immunology

CD36 ligands promote sterile inflammation through assembly of a Toll-like receptor 4 and 6 heterodimer

(2009) Cameron R Stewart et al.   NATURE IMMUNOLOGY

Network mechanisms of gamma oscillations in the CA3 region of the hippocampus

(2009) Norbert Hájos et al.   NEURAL NETWORKS

Systemic inflammation and disease progression in Alzheimer disease

(2009) C. Holmes et al.   NEUROLOGY

Interferon-γ directly induces neurotoxicity through a neuron specific, calcium-permeable complex of IFN-γ receptor and AMPA GluR1 receptor

(2008) Tetsuya Mizuno et al.   FASEB JOURNAL

c-Jun N-terminal kinase and p38 mitogen-activated protein kinase mediate double-strand RNA-induced inducible nitric oxide synthase expression in microglial cells

(2008) Pil-Jae Kong et al.   NEUROSCIENCE LETTERS

Microglial activation and TNF  production mediate altered CNS excitability following peripheral inflammation

(2008) K. Riazi et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

A critical link between Toll-like receptor 3 and type II interferon signaling pathways in antiviral innate immunity

(2008) H. Negishi et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Glial toll-like receptor signaling in central nervous system infection and autoimmunity

(2007) Pamela A. Carpentier et al.   BRAIN BEHAVIOR AND IMMUNITY