Microglia and sexual differentiation of the developing brain: A focus on ontogeny and intrinsic factors

Glucose transporter 1 critically controls microglial activation through facilitating glycolysis

(2019) Luxi Wang et al.   Molecular Neurodegeneration

Microglial Phagocytosis of Newborn Cells Is Induced by Endocannabinoids and Sculpts Sex Differences in Juvenile Rat Social Play

(2019) Jonathan W. VanRyzin et al.   NEURON

Microglia and sexual differentiation of the developing brain: A focus on extrinsic factors

(2019) Jonathan W. VanRyzin et al.   GLIA

Microbiome Influences Prenatal and Adult Microglia in a Sex-Specific Manner

(2018) Morgane Sonia Thion et al.   CELL

Sexual dimorphism of microglia and synapses during mouse postnatal development

(2018) Laetitia Weinhard et al.   Developmental Neurobiology

Microglia: Driving critical periods and sexual differentiation of the brain

(2018) Jonathan W. VanRyzin et al.   Developmental Neurobiology

High-Dimensional Single-Cell Mapping of Central Nervous System Immune Cells Reveals Distinct Myeloid Subsets in Health, Aging, and Disease

(2018) Dunja Mrdjen et al.   IMMUNITY

Peripherally derived macrophages can engraft the brain independent of irradiation and maintain an identity distinct from microglia

(2018) James C. Cronk et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Microglial control of astrocytes in response to microbial metabolites

(2018) Veit Rothhammer et al.   NATURE

Re-evaluating microglia expression profiles using RiboTag and cell isolation strategies

(2018) Zhana Haimon et al.   NATURE IMMUNOLOGY

Single-cell mass cytometry reveals distinct populations of brain myeloid cells in mouse neuroinflammation and neurodegeneration models

(2018) Bahareh Ajami et al.   NATURE NEUROSCIENCE

Epigenetic regulation of brain region-specific microglia clearance activity

(2018) Pinar Ayata et al.   NATURE NEUROSCIENCE

Yolk sac macrophage progenitors traffic to the embryo during defined stages of development

(2018) C. Stremmel et al.   Nature Communications

Sex-Specific Features of Microglia from Adult Mice

(2018) Alessandro Villa et al.   Cell Reports

Microglia heterogeneity along a spatio-temporal axis: More questions than answers

(2018) Aymeric Silvin et al.   GLIA

Mast Cells in the Developing Brain Determine Adult Sexual Behavior

(2018) Kathryn M. Lenz et al.   JOURNAL OF NEUROSCIENCE

Microglial dopamine receptor elimination defines sex-specific nucleus accumbens development and social behavior in adolescent rats

(2018) Ashley M. Kopec et al.   Nature Communications

Transcriptional and Translational Differences of Microglia from Male and Female Brains

(2018) Dilansu Guneykaya et al.   Cell Reports

miR‐223 promotes regenerative myeloid cell phenotype and function in the demyelinated central nervous system

(2018) Dylan A. Galloway et al.   GLIA

Single-Cell RNA Sequencing of Microglia throughout the Mouse Lifespan and in the Injured Brain Reveals Complex Cell-State Changes

(2018) Timothy R. Hammond et al.   IMMUNITY

Human microglia regional heterogeneity and phenotypes determined by multiplexed single-cell mass cytometry

(2018) Chotima Böttcher et al.   NATURE NEUROSCIENCE

Developmental Heterogeneity of Microglia and Brain Myeloid Cells Revealed by Deep Single-Cell RNA Sequencing

(2018) Qingyun Li et al.   NEURON

Microglia and early brain development: An intimate journey

(2018) Morgane S. Thion et al.   SCIENCE

Generation of a microglial developmental index in mice and in humans reveals a sex difference in maturation and immune reactivity

(2017) Richa Hanamsagar et al.   GLIA

Biochemical Underpinnings of Immune Cell Metabolic Phenotypes

(2017) Benjamin A. Olenchock et al.   IMMUNITY

Gender-Based Cerebral Perfusion Differences in 46,034 Functional Neuroimaging Scans

(2017) Daniel G. Amen et al.   JOURNAL OF ALZHEIMERS DISEASE

Single-cell sequencing reveals dissociation-induced gene expression in tissue subpopulations

(2017) Susanne C van den Brink et al.   NATURE METHODS

Local Cues Establish and Maintain Region-Specific Phenotypes of Basal Ganglia Microglia

(2017) Lindsay M. De Biase et al.   NEURON

Macrophage Immunometabolism: Where Are We (Going)?

(2017) Jan Van den Bossche et al.   TRENDS IN IMMUNOLOGY

Sex differences in microglial CX3CR1 signalling determine obesity susceptibility in mice

(2017) Mauricio D. Dorfman et al.   Nature Communications

Precision Stroke Animal Models: the Permanent MCAO Model Should Be the Primary Model, Not Transient MCAO

(2017) Devin W. McBride et al.   Translational Stroke Research

Exploring Non-Metabolic Functions of Glycolytic Enzymes in Immunity

(2017) Scott M. Seki et al.   Frontiers in Immunology

Sex differences of human cortical blood flow and energy metabolism

(2016) Joel Aanerud et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

Sex-dependent mitochondrial respiratory impairment and oxidative stress in a rat model of neonatal hypoxic-ischemic encephalopathy

(2016) Tyler G. Demarest et al.   JOURNAL OF NEUROCHEMISTRY

Highly multiplexed simultaneous detection of RNAs and proteins in single cells

(2016) Andreas P Frei et al.   NATURE METHODS

Adult mouse cortical cell taxonomy revealed by single cell transcriptomics

(2016) Bosiljka Tasic et al.   NATURE NEUROSCIENCE

A polarizing question: do M1 and M2 microglia exist?

(2016) Richard M Ransohoff   NATURE NEUROSCIENCE

New tools for studying microglia in the mouse and human CNS

(2016) Mariko L. Bennett et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Microglia development follows a stepwise program to regulate brain homeostasis

(2016) O. Matcovitch-Natan et al.   SCIENCE

Microglial M1/M2 polarization and metabolic states

(2015) Ruben Orihuela et al.   BRITISH JOURNAL OF PHARMACOLOGY

Effect of Sex Differences on Brain Mitochondrial Function and Its Suppression by Ovariectomy and in Aged Mice

(2015) Pauline Gaignard et al.   ENDOCRINOLOGY

Surprising origins of sex differences in the brain

(2015) Margaret M. McCarthy et al.   HORMONES AND BEHAVIOR

Cell types in the mouse cortex and hippocampus revealed by single-cell RNA-seq

(2015) A. Zeisel et al.   SCIENCE

Ontogeny of Tissue-Resident Macrophages

(2015) Guillaume Hoeffel et al.   Frontiers in Immunology

Time and Demand are Two Critical Dimensions of Immunometabolism: The Process of Macrophage Activation and the Pentose Phosphate Pathway

(2015) Csörsz Nagy et al.   Frontiers in Immunology

Characterizing Newly Repopulated Microglia in the Adult Mouse: Impacts on Animal Behavior, Cell Morphology, and Neuroinflammation

(2015) Monica R. P. Elmore et al.   PLoS One

Microglia shape corpus callosum axon tract fasciculation: functional impact of prenatal inflammation

(2014) Lorena Pont-Lezica et al.   EUROPEAN JOURNAL OF NEUROSCIENCE

Sex differences in behavioral outcome following neonatal hypoxia ischemia: Insights from a clinical meta-analysis and a rodent model of induced hypoxic ischemic brain injury

(2014) Amanda L. Smith et al.   EXPERIMENTAL NEUROLOGY

Impact of puberty on the evolution of cerebral perfusion during adolescence

(2014) T. D. Satterthwaite et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Neural progenitor cells orchestrate microglia migration and positioning into the developing cortex

(2014) Benedetta Arnò et al.   Nature Communications

Microglia Modulate Wiring of the Embryonic Forebrain

(2014) Paola Squarzoni et al.   Cell Reports

Maternal inheritance of mitochondrial DNA by diverse mechanisms to eliminate paternal mitochondrial DNA

(2013) Miyuki Sato et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

Microglia Promote Learning-Dependent Synapse Formation through Brain-Derived Neurotrophic Factor

(2013) Christopher N. Parkhurst et al.   CELL

Inflammatory response of microglial BV-2 cells includes a glycolytic shift and is modulated by mitochondrial glucose-regulated protein 75/mortalin

(2013) Ludmila A. Voloboueva et al.   FEBS LETTERS

The Y chromosome as a regulatory element shaping immune cell transcriptomes and susceptibility to autoimmune disease

(2013) L. K. Case et al.   GENOME RESEARCH

Metabolic Pathways in Immune Cell Activation and Quiescence

(2013) Erika L. Pearce et al.   IMMUNITY

Microglia Regulate the Number of Neural Precursor Cells in the Developing Cerebral Cortex

(2013) C. L. Cunningham et al.   JOURNAL OF NEUROSCIENCE

Microglia Are Essential to Masculinization of Brain and Behavior

(2013) K. M. Lenz et al.   JOURNAL OF NEUROSCIENCE

Microglia express distinct M1 and M2 phenotypic markers in the postnatal and adult central nervous system in male and female mice

(2013) Jessica M. Crain et al.   JOURNAL OF NEUROSCIENCE RESEARCH

Characterizing the normative profile of 18F-FDG PET brain imaging: Sex difference, aging effect, and cognitive reserve

(2013) Hiroshi Yoshizawa et al.   PSYCHIATRY RESEARCH-NEUROIMAGING

Sex and gender issues in multiple sclerosis

(2013) Hanne F. Harbo et al.   Therapeutic Advances in Neurological Disorders

The Sedoheptulose Kinase CARKL Directs Macrophage Polarization through Control of Glucose Metabolism

(2012) Arvand Haschemi et al.   Cell Metabolism

Mitochondria, Maternal Inheritance, and Male Aging

(2012) M. Florencia Camus et al.   CURRENT BIOLOGY

Resveratrol affects differently rat liver and brain mitochondrial bioenergetics and oxidative stress in vitro: Investigation of the role of gender

(2012) Ana C. Moreira et al.   FOOD AND CHEMICAL TOXICOLOGY

The “quad-partite” synapse: Microglia-synapse interactions in the developing and mature CNS

(2012) Dorothy P. Schafer et al.   GLIA

Complex invasion pattern of the cerebral cortex bymicroglial cells during development of the mouse embryo

(2012) Nina Swinnen et al.   GLIA

An unconventional role for miRNA: let-7 activates Toll-like receptor 7 and causes neurodegeneration

(2012) Sabrina M Lehmann et al.   NATURE NEUROSCIENCE

Microglia Sculpt Postnatal Neural Circuits in an Activity and Complement-Dependent Manner

(2012) Dorothy P. Schafer et al.   NEURON

A deep profiler's guide to cytometry

(2012) Sean C. Bendall et al.   TRENDS IN IMMUNOLOGY

X-chromosome-located microRNAs in immunity: Might they explain male/female differences?

(2011) Iris Pinheiro et al.   BIOESSAYS

Age and Sex-Related Changes in Rat Brain Mitochondrial Function

(2011) Rocío Guevara et al.   CELLULAR PHYSIOLOGY AND BIOCHEMISTRY

Age and sex-related changes in rat brain mitochondrial oxidative status

(2011) Rocío Guevara et al.   EXPERIMENTAL GERONTOLOGY

Maternal Smoking and Fetal Sex Significantly Affect Metabolic Enzyme Expression in the Human Fetal Liver

(2011) Peter J. O'Shaughnessy et al.   JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM

CCL2 recruits inflammatory monocytes to facilitate breast-tumour metastasis

(2011) Bin-Zhi Qian et al.   NATURE

Synaptic Pruning by Microglia Is Necessary for Normal Brain Development

(2011) R. C. Paolicelli et al.   SCIENCE

Hematopoietic Origin of Pathological Grooming in Hoxb8 Mutant Mice

(2010) Shau-Kwaun Chen et al.   CELL

Microglia in the developing brain: from immunity to behaviour

(2010) Timm Schlegelmilch et al.   CURRENT OPINION IN NEUROBIOLOGY

Developmental Time Course of Estradiol, Testosterone, and Dihydrotestosterone Levels in Discrete Regions of Male and Female Rat Brain

(2010) Anne T. M. Konkle et al.   ENDOCRINOLOGY

Early microglial colonization of the human forebrain and possible involvement in periventricular white-matter injury of preterm infants

(2010) Catherine Verney et al.   JOURNAL OF ANATOMY

Fate Mapping Analysis Reveals That Adult Microglia Derive from Primitive Macrophages

(2010) F. Ginhoux et al.   SCIENCE

Paternally biased X inactivation in mouse neonatal brain

(2010) Xu Wang et al.   GENOME BIOLOGY

Cutting Edge: The Y Chromosome Controls the Age-Dependent Experimental Allergic Encephalomyelitis Sexual Dimorphism in SJL/J Mice

(2009) K. M. Spach et al.   JOURNAL OF IMMUNOLOGY

An empirical analysis of the precision of estimating the numbers of neurons and glia in human neocortex using a fractionator-design with sub-sampling

(2009) Lise Lyck et al.   JOURNAL OF NEUROSCIENCE METHODS

Region-specific expression of immunoregulatory proteins on microglia in the healthy CNS

(2008) Alexander H. de Haas et al.   GLIA

The role of androgen receptors in the masculinization of brain and behavior: What we've learned from the testicular feminization mutation

(2008) Damian G. Zuloaga et al.   HORMONES AND BEHAVIOR

Estradiol and the Developing Brain

(2008) MARGARET M. McCARTHY   PHYSIOLOGICAL REVIEWS

Neocortical glial cell numbers in human brains

(2007) D.P. Pelvig et al.   NEUROBIOLOGY OF AGING