TLR2-induced astrocyte MMP9 activation compromises the blood brain barrier and exacerbates intracerebral hemorrhage in animal models

Neutrophil depletion reduces edema formation and tissue loss following traumatic brain injury in mice

(2012) Ellinor Kenne et al.   Journal of Neuroinflammation

Toll-like receptors in health and disease in the brain: mechanisms and therapeutic potential

(2011) Mark L. Hanke et al.   CLINICAL SCIENCE

Redox Regulation of the Intrinsic Pathway in Neuronal Apoptosis

(2010) James L. Franklin   ANTIOXIDANTS & REDOX SIGNALING

Blocking TLR2 in vivo Protects against Accumulation of Inflammatory Cells and Neuronal Injury in Experimental Stroke

(2010) Gina Ziegler et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

Preclinical and clinical research on inflammation after intracerebral hemorrhage

(2010) Jian Wang   PROGRESS IN NEUROBIOLOGY

High-Mobility Group Box 1 Promotes Metalloproteinase-9 Upregulation Through Toll-Like Receptor 4 After Cerebral Ischemia

(2010) Jianhua Qiu et al.   STROKE

Differential roles of TLR2 and TLR4 in acute focal cerebral ischemia/reperfusion injury in mice

(2009) Fang Hua et al.   BRAIN RESEARCH

Neutrophils contribute to intracerebral haemorrhages after treatment with recombinant tissue plasminogen activator following cerebral ischaemia

(2009) Sophie Gautier et al.   BRITISH JOURNAL OF PHARMACOLOGY

CD47 gene knockout protects against transient focal cerebral ischemia in mice

(2009) Guang Jin et al.   EXPERIMENTAL NEUROLOGY

Heat Shock Protein 96 Is Elevated in Rheumatoid Arthritis and Activates Macrophages Primarily via TLR2 Signaling

(2009) Q.-Q. Huang et al.   JOURNAL OF IMMUNOLOGY

Intracerebral haemorrhage

(2009) Adnan I Qureshi et al.   LANCET

HMGB1 Mediates Endogenous TLR2 Activation and Brain Tumor Regression

(2009) James F Curtin et al.   PLOS MEDICINE

Role of microglial IKKβ in kainic acid-induced hippocampal neuronal cell death

(2008) Ik-Hyun Cho et al.   BRAIN

Reduced brain injury in CD18-deficient mice after experimental intracerebral hemorrhage

(2008) Elena Titova et al.   JOURNAL OF NEUROSCIENCE RESEARCH

Diverse roles of matrix metalloproteinases and tissue inhibitors of metalloproteinases in neuroinflammation and cerebral ischemia

(2008) E. Candelario-Jalil et al.   NEUROSCIENCE

Toll-like receptor 2 contributes to glial cell activation and heme oxygenase-1 expression in traumatic brain injury

(2007) Chanhee Park et al.   NEUROSCIENCE LETTERS