Induced Expression of kir6.2 in A1 Astrocytes Propagates Inflammatory Neurodegeneration via Drp1-dependent Mitochondrial Fission
Published 2021 View Full Article
- Home
- Publications
- Publication Search
- Publication Details
Title
Induced Expression of kir6.2 in A1 Astrocytes Propagates Inflammatory Neurodegeneration via Drp1-dependent Mitochondrial Fission
Authors
Keywords
-
Journal
Frontiers in Pharmacology
Volume 11, Issue -, Pages -
Publisher
Frontiers Media SA
Online
2021-01-28
DOI
10.3389/fphar.2020.618992
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- Pyridoxine induces glutathione synthesis via PKM2-mediated Nrf2 transactivation and confers neuroprotection
- (2020) Yao Wei et al. Nature Communications
- Concerted Action of AMPK and Sirtuin-1 Induces Mitochondrial Fragmentation Upon Inhibition of Ca2+ Transfer to Mitochondria
- (2020) Alenka Lovy et al. Frontiers in Cell and Developmental Biology
- Glial cells in Parkinson´s disease: protective or deleterious?
- (2020) Ana V. Domingues et al. CELLULAR AND MOLECULAR LIFE SCIENCES
- Brain energy rescue: an emerging therapeutic concept for neurodegenerative disorders of ageing
- (2020) Stephen C. Cunnane et al. NATURE REVIEWS DRUG DISCOVERY
- The Role of Astrocytes in CNS Inflammation
- (2020) Federico Giovannoni et al. TRENDS IN IMMUNOLOGY
- Glia Crosstalk in Neuroinflammatory Diseases
- (2020) Ada Bernaus et al. Frontiers in Cellular Neuroscience
- Abnormal Mitochondrial Quality Control in Neurodegenerative Diseases
- (2020) Xu Yan et al. Frontiers in Cellular Neuroscience
- Microglia and astrocyte dysfunction in parkinson's disease
- (2020) Tae-In Kam et al. NEUROBIOLOGY OF DISEASE
- Microglia and Astrocytes in Disease: Dynamic Duo or Partners in Crime?
- (2020) Shane A. Liddelow et al. TRENDS IN IMMUNOLOGY
- CaMKIV regulates mitochondrial dynamics during sepsis
- (2020) Xianghong Zhang et al. CELL CALCIUM
- Aβ1-42 increases the expression of neural KATP subunits Kir6.2/SUR1 via the NF-κB, p38 MAPK and PKC signal pathways in rat primary cholinergic neurons
- (2019) Y Li et al. HUMAN & EXPERIMENTAL TOXICOLOGY
- Lipopolysaccharide-Induced Neuroinflammation as a Bridge to Understand Neurodegeneration
- (2019) Carla Ribeiro Alvares Batista et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- The A1 astrocyte paradigm: New avenues for pharmacological intervention in neurodegeneration
- (2019) Jared T. Hinkle et al. MOVEMENT DISORDERS
- The astrocyte biochemistry
- (2019) Débora G. Souza et al. SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY
- Identification of an ATP-sensitive potassium channel in mitochondria
- (2019) Angela Paggio et al. NATURE
- Fragmented mitochondria released from microglia trigger A1 astrocytic response and propagate inflammatory neurodegeneration
- (2019) Amit U. Joshi et al. NATURE NEUROSCIENCE
- Glial mitochondrial function and dysfunction in health and neurodegeneration
- (2019) Kevin McAvoy et al. MOLECULAR AND CELLULAR NEUROSCIENCE
- NFκB mediated elevation of KCNJ11 promotes tumor progression of hepatocellular carcinoma through interaction of lactate dehydrogenase A
- (2018) Ke Zhang et al. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
- Dopamine D2 receptor restricts astrocytic NLRP3 inflammasome activation via enhancing the interaction of β-arrestin2 and NLRP3
- (2018) Jialei Zhu et al. CELL DEATH AND DIFFERENTIATION
- Kir6.2, the pore-forming subunit of ATP-sensitive K+ channels, is overexpressed in human post-traumatic brain contusions
- (2018) Lidia Castro et al. JOURNAL OF NEUROTRAUMA
- Kir6.2 Deficiency Promotes Mesencephalic Neural Precursor Cell Differentiation via Regulating miR-133b/GDNF in a Parkinson’s Disease Mouse Model
- (2018) Yan Zhou et al. MOLECULAR NEUROBIOLOGY
- Block of A1 astrocyte conversion by microglia is neuroprotective in models of Parkinson’s disease
- (2018) Seung Pil Yun et al. NATURE MEDICINE
- Normal aging induces A1-like astrocyte reactivity
- (2018) Laura E. Clarke et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Functional dissection of astrocyte-secreted proteins: Implications in brain health and diseases
- (2018) Mithilesh Kumar Jha et al. PROGRESS IN NEUROBIOLOGY
- SUR1, TRPM4 and KIR6.2 – role in hemorrhagic progression of contusion
- (2018) Volodymyr Gerzanich et al. JOURNAL OF NEUROTRAUMA
- Deletion of Kir6.2/SUR1 potassium channels rescues diminishing of DA neurons via decreasing iron accumulation in PD
- (2018) Qian Zhang et al. MOLECULAR AND CELLULAR NEUROSCIENCE
- Neuroinflammation in the central nervous system: Symphony of glial cells
- (2018) Qiao‐qiao Yang et al. GLIA
- Neurotoxic reactive astrocytes are induced by activated microglia
- (2017) Shane A. Liddelow et al. NATURE
- Parkinson disease
- (2017) Werner Poewe et al. Nature Reviews Disease Primers
- Phosphorylation of the mitochondrial ATP-sensitive potassium channel occurs independently of PKCε in turtle brain
- (2016) Peter John Hawrysh et al. COMPARATIVE BIOCHEMISTRY AND PHYSIOLOGY B-BIOCHEMISTRY & MOLECULAR BIOLOGY
- Adaptive regulation of the brain’s antioxidant defences by neurons and astrocytes
- (2016) Paul S. Baxter et al. FREE RADICAL BIOLOGY AND MEDICINE
- Converging roles of ion channels, calcium, metabolic stress, and activity pattern ofSubstantia nigradopaminergic neurons in health and Parkinson's disease
- (2016) Johanna Duda et al. JOURNAL OF NEUROCHEMISTRY
- Aberrant expression of the pore-forming KATP channel subunit Kir6.2 in hippocampal reactive astrocytes in the 3xTg-AD mouse model and human Alzheimer’s disease
- (2016) Chelsea M. Griffith et al. NEUROSCIENCE
- Dopamine midbrain neurons in health and Parkinson’s disease: Emerging roles of voltage-gated calcium channels and ATP-sensitive potassium channels
- (2015) E. Dragicevic et al. NEUROSCIENCE
- Kir6.2 knockout aggravates lipopolysaccharide-induced mouse liver injury via enhancing NLRP3 inflammasome activation
- (2013) Ren-Hong Du et al. JOURNAL OF GASTROENTEROLOGY
- Physiological and Pathological Significance of Dynamin-Related Protein 1 (Drp1)-Dependent Mitochondrial Fission in the Nervous System
- (2013) Bongki Cho et al. Experimental Neurobiology
- K-ATP channels in dopamine substantia nigra neurons control bursting and novelty-induced exploration
- (2012) Julia Schiemann et al. NATURE NEUROSCIENCE
- Aquaporin-4 Deficiency Impairs Synaptic Plasticity and Associative Fear Memory in the Lateral Amygdala: Involvement of Downregulation of Glutamate Transporter-1 Expression
- (2012) Yan-Kun Li et al. NEUROPSYCHOPHARMACOLOGY
- Animal models of Parkinson's disease: a source of novel treatments and clues to the cause of the disease
- (2011) Susan Duty et al. BRITISH JOURNAL OF PHARMACOLOGY
- Mitochondrial fragmentation in neurodegeneration
- (2008) Andrew B. Knott et al. NATURE REVIEWS NEUROSCIENCE
- Kir6.2 knockout alters neurotransmitter release in mouse striatum: An in vivo microdialysis study
- (2008) Xue-Ru Shi et al. NEUROSCIENCE LETTERS
Discover Peeref hubs
Discuss science. Find collaborators. Network.
Join a conversationAsk a Question. Answer a Question.
Quickly pose questions to the entire community. Debate answers and get clarity on the most important issues facing researchers.
Get Started