Dopamine D2 receptor restricts astrocytic NLRP3 inflammasome activation via enhancing the interaction of β-arrestin2 and NLRP3

Metformin Prevents Dopaminergic Neuron Death in MPTP/P-Induced Mouse Model of Parkinson’s Disease via Autophagy and Mitochondrial ROS Clearance

(2016) Ming Lu et al.   INTERNATIONAL JOURNAL OF NEUROPSYCHOPHARMACOLOGY

Ubiquitin-Related Roles of β-Arrestins in Endocytic Trafficking and Signal Transduction

(2016) Pierre-Yves Jean-Charles et al.   JOURNAL OF CELLULAR PHYSIOLOGY

Therapeutic approaches in Parkinson's disease and related disorders

(2016) Elvira Valera et al.   JOURNAL OF NEUROCHEMISTRY

Maternal Omega-3 Supplement Improves Dopaminergic System in Pre- and Postnatal Inflammation-Induced Neurotoxicity in Parkinson’s Disease Model

(2016) Ana Marcia Delattre et al.   MOLECULAR NEUROBIOLOGY

Pramipexole, a Dopamine D2/D3 Receptor-Preferring Agonist, Prevents Experimental Autoimmune Encephalomyelitis Development in Mice

(2016) Vicente Lieberknecht et al.   MOLECULAR NEUROBIOLOGY

β-Arrestin biosensors reveal a rapid, receptor-dependent activation/deactivation cycle

(2016) Susanne Nuber et al.   NATURE

A novel dual GLP-1 and GIP incretin receptor agonist is neuroprotective in a mouse model of Parkinson’s disease by reducing chronic inflammation in the brain

(2016) Lijun Cao et al.   NEUROREPORT

Density of GFAP-immunoreactive astrocytes is decreased in left hippocampi in major depressive disorder

(2016) J.A. Cobb et al.   NEUROSCIENCE

TLR4 Signaling in MPP+-Induced Activation of BV-2 Cells

(2016) Peng Zhou et al.   NEURAL PLASTICITY

The emerging roles of β-arrestins in fibrotic diseases

(2015) Yuan-jing Gu et al.   ACTA PHARMACOLOGICA SINICA

Dopamine Controls Systemic Inflammation through Inhibition of NLRP3 Inflammasome

(2015) Yiqing Yan et al.   CELL

Erratum: Multifaceted role of β-arrestins in inflammation and disease

(2015) D Sharma et al.   GENES AND IMMUNITY

Anti-inflammatory effects of fimasartan via Akt, ERK, and NFκB pathways on astrocytes stimulated by hemolysate

(2015) Xiu-Li Yang et al.   INFLAMMATION RESEARCH

Outside-in signaling - a brief review of GPCR signaling with a focus on the Drosophila GPCR family

(2015) C. D. Hanlon et al.   JOURNAL OF CELL SCIENCE

β-arrestin1 Is Critical for the Full Activation of NLRP3 and NLRC4 Inflammasomes

(2015) Kairui Mao et al.   JOURNAL OF IMMUNOLOGY

NALP3 inflammasome activation in protein misfolding diseases

(2015) Fushan Shi et al.   LIFE SCIENCES

Emerging Functional Divergence of β-Arrestin Isoforms in GPCR Function

(2015) Ashish Srivastava et al.   TRENDS IN ENDOCRINOLOGY AND METABOLISM

Elusive roles for reactive astrocytes in neurodegenerative diseases

(2015) Lucile Ben Haim et al.   Frontiers in Cellular Neuroscience

Neuroinflammation and Depression: Microglia Activation, Extracellular Microvesicles and microRNA Dysregulation

(2015) Dora Brites et al.   Frontiers in Cellular Neuroscience

Dopamine Receptors and Neurodegeneration

(2015) Claudia Rangel-Barajas et al.   Aging and Disease

Neuroinflammation in Parkinson’s disease and its potential as therapeutic target

(2015) Qinqin Wang et al.   Translational Neurodegeneration

Receptor, Ligand and Transducer Contributions to Dopamine D2 Receptor Functional Selectivity

(2015) Sean M. Peterson et al.   PLoS One

IL-1β and IL-18: inflammatory markers or mediators of hypertension?

(2014) S M Krishnan et al.   BRITISH JOURNAL OF PHARMACOLOGY

β-Arrestin 2 Negatively Regulates Toll-like Receptor 4 (TLR4)-triggered Inflammatory Signaling via Targeting p38 MAPK and Interleukin 10

(2014) Hui Li et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Neuroendocrine and metabolic components of dopamine agonist amelioration of metabolic syndrome in SHR rats

(2014) Michael Ezrokhi et al.   Diabetology & Metabolic Syndrome

Omega-3 Fatty Acids Prevent Inflammation and Metabolic Disorder through Inhibition of NLRP3 Inflammasome Activation

(2013) Yiqing Yan et al.   IMMUNITY

β-Arrestins as Potential Therapeutic Targets for Alzheimer’s Disease

(2013) Teng Jiang et al.   MOLECULAR NEUROBIOLOGY

Selective regulation of recombinantly expressed mGlu7 metabotropic glutamate receptors by G protein-coupled receptor kinases and arrestins

(2013) L. Iacovelli et al.   NEUROPHARMACOLOGY

β-arrestin2 in Infiltrated Macrophages Inhibits Excessive Inflammation after Myocardial Infarction

(2013) Kenji Watari et al.   PLoS One

Deficiency of  -arrestin1 ameliorates collagen-induced arthritis with impaired TH17 cell differentiation

(2013) J. Li et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Recent molecular approaches to understanding astrocyte function in vivo

(2013) David Davila et al.   Frontiers in Cellular Neuroscience

Inflammatory Mediators Alter the Astrocyte Transcriptome and Calcium Signaling Elicited by Multiple G-Protein-Coupled Receptors

(2012) M. E. Hamby et al.   JOURNAL OF NEUROSCIENCE

Suppression of neuroinflammation by astrocytic dopamine D2 receptors via αB-crystallin

(2012) Wei Shao et al.   NATURE

Deficient Dopamine D2 Receptor Function Causes Renal Inflammation Independently of High Blood Pressure

(2012) Yanrong Zhang et al.   PLoS One

Bromocriptine methylate suppresses glial inflammation and moderates disease progression in a mouse model of amyotrophic lateral sclerosis

(2011) Kazunori Tanaka et al.   EXPERIMENTAL NEUROLOGY

 -Arrestin Deficiency Protects Against Pulmonary Fibrosis in Mice and Prevents Fibroblast Invasion of Extracellular Matrix

(2011) A. K. Lovgren et al.   Science Translational Medicine

β-Arrestin1 mediates nicotinic acid–induced flushing, but not its antilipolytic effect, in mice

(2009) Robert W. Walters et al.   JOURNAL OF CLINICAL INVESTIGATION

Overexpression of β-Arrestin 2 in Peripheral Blood Mononuclear Cells of Patients With Cryptococcal Meningitis

(2009) Rong Xia et al.   JOURNAL OF INTERFERON AND CYTOKINE RESEARCH