The A1 astrocyte paradigm: New avenues for pharmacological intervention in neurodegeneration
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Title
The A1 astrocyte paradigm: New avenues for pharmacological intervention in neurodegeneration
Authors
Keywords
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Journal
MOVEMENT DISORDERS
Volume -, Issue -, Pages -
Publisher
Wiley
Online
2019-05-29
DOI
10.1002/mds.27718
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Note: Only part of the references are listed.- PET imaging of microglia by targeting macrophage colony-stimulating factor 1 receptor (CSF1R)
- (2019) Andrew G. Horti et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Patient-Specific iPSC-Derived Astrocytes Contribute to Non-Cell-Autonomous Neurodegeneration in Parkinson's Disease
- (2019) Angelique di Domenico et al. Stem Cell Reports
- Glutathione S-transferases promote proinflammatory astrocyte-microglia communication during brain inflammation
- (2019) Shin-ichi Kano et al. Science Signaling
- High complement levels in astrocyte-derived exosomes of Alzheimer disease
- (2018) Edward J. Goetzl et al. ANNALS OF NEUROLOGY
- Mutant LRRK2 mediates peripheral and central immune responses leading to neurodegeneration in vivo
- (2018) Elena Kozina et al. BRAIN
- Parkin deficiency modulates NLRP3 inflammasome activation by attenuating an A20-dependent negative feedback loop
- (2018) François Mouton-Liger et al. GLIA
- Early long-term administration of the CSF1R inhibitor PLX3397 ablates microglia and reduces accumulation of intraneuronal amyloid, neuritic plaque deposition and pre-fibrillar oligomers in 5XFAD mouse model of Alzheimer’s disease
- (2018) Justyna Sosna et al. Molecular Neurodegeneration
- Block of A1 astrocyte conversion by microglia is neuroprotective in models of Parkinson’s disease
- (2018) Seung Pil Yun et al. NATURE MEDICINE
- A 3D human triculture system modeling neurodegeneration and neuroinflammation in Alzheimer’s disease
- (2018) Joseph Park et al. NATURE NEUROSCIENCE
- Microglia-mediated recovery from ALS-relevant motor neuron degeneration in a mouse model of TDP-43 proteinopathy
- (2018) Krista J. Spiller et al. NATURE NEUROSCIENCE
- Normal aging induces A1-like astrocyte reactivity
- (2018) Laura E. Clarke et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Functional variants in the LRRK2 gene confer shared effects on risk for Crohn’s disease and Parkinson’s disease
- (2018) Ken Y. Hui et al. Science Translational Medicine
- A transcriptomic atlas of aged human microglia
- (2018) Marta Olah et al. Nature Communications
- The Aging Astrocyte Transcriptome from Multiple Regions of the Mouse Brain
- (2018) Matthew M. Boisvert et al. Cell Reports
- What Effects Might Exenatide have on Non-Motor Symptoms in Parkinson’s Disease: A Post Hoc Analysis
- (2018) Dilan Athauda et al. Journal of Parkinsons Disease
- Anti–Tumor Necrosis Factor Therapy and Incidence of Parkinson Disease Among Patients With Inflammatory Bowel Disease
- (2018) Inga Peter et al. JAMA Neurology
- Post hoc analysis of the Exenatide-PD trial - factors that predict response
- (2018) Dilan Athauda et al. EUROPEAN JOURNAL OF NEUROSCIENCE
- Clearance of senescent glial cells prevents tau-dependent pathology and cognitive decline
- (2018) Tyler J. Bussian et al. NATURE
- Animal models of neurodegenerative diseases
- (2018) Ted M. Dawson et al. NATURE NEUROSCIENCE
- Single-Cell RNA Sequencing of Microglia throughout the Mouse Lifespan and in the Injured Brain Reveals Complex Cell-State Changes
- (2018) Timothy R. Hammond et al. IMMUNITY
- Downregulation of miR-7116-5p in microglia by MPP+ sensitizes TNF-α production to induce dopaminergic neuron damage
- (2017) Qian He et al. GLIA
- The TREM2-APOE Pathway Drives the Transcriptional Phenotype of Dysfunctional Microglia in Neurodegenerative Diseases
- (2017) Susanne Krasemann et al. IMMUNITY
- Reactive Astrocytes: Production, Function, and Therapeutic Potential
- (2017) Shane A. Liddelow et al. IMMUNITY
- Human Astrocytes Transfer Aggregated Alpha-Synuclein via Tunneling Nanotubes
- (2017) Jinar Rostami et al. JOURNAL OF NEUROSCIENCE
- Exenatide once weekly versus placebo in Parkinson's disease: a randomised, double-blind, placebo-controlled trial
- (2017) Dilan Athauda et al. LANCET
- Assessment of neuroinflammation in patients with idiopathic rapid-eye-movement sleep behaviour disorder: a case-control study
- (2017) Morten Gersel Stokholm et al. LANCET NEUROLOGY
- Extensive uptake of α-synuclein oligomers in astrocytes results in sustained intracellular deposits and mitochondrial damage
- (2017) Veronica Lindström et al. MOLECULAR AND CELLULAR NEUROSCIENCE
- Aging and Parkinson's disease: Different sides of the same coin?
- (2017) Timothy J. Collier et al. MOVEMENT DISORDERS
- T cells from patients with Parkinson’s disease recognize α-synuclein peptides
- (2017) David Sulzer et al. NATURE
- Neurotoxic reactive astrocytes are induced by activated microglia
- (2017) Shane A. Liddelow et al. NATURE
- A meta-analysis of genome-wide association studies identifies 17 new Parkinson's disease risk loci
- (2017) Diana Chang et al. NATURE GENETICS
- Selective neuronal vulnerability in Parkinson disease
- (2017) D. James Surmeier et al. NATURE REVIEWS NEUROSCIENCE
- Non-motor features of Parkinson disease
- (2017) Anthony H.V. Schapira et al. NATURE REVIEWS NEUROSCIENCE
- Local Cues Establish and Maintain Region-Specific Phenotypes of Basal Ganglia Microglia
- (2017) Lindsay M. De Biase et al. NEURON
- Cell-specific and region-specific transcriptomics in the multiple sclerosis model: Focus on astrocytes
- (2017) Noriko Itoh et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- TREM2, Microglia, and Neurodegenerative Diseases
- (2017) Felix L. Yeh et al. TRENDS IN MOLECULAR MEDICINE
- Coupled Proliferation and Apoptosis Maintain the Rapid Turnover of Microglia in the Adult Brain
- (2017) Katharine Askew et al. Cell Reports
- Parkinson disease
- (2017) Werner Poewe et al. Nature Reviews Disease Primers
- Pharmacological targeting of CSF1R inhibits microglial proliferation and prevents the progression of Alzheimer’s-like pathology
- (2016) Adrian Olmos-Alonso et al. BRAIN
- Eliminating microglia in Alzheimer’s mice prevents neuronal loss without modulating amyloid-β pathology
- (2016) Elizabeth E. Spangenberg et al. BRAIN
- Gut Microbiota Regulate Motor Deficits and Neuroinflammation in a Model of Parkinson’s Disease
- (2016) Timothy R. Sampson et al. CELL
- NF-κB Restricts Inflammasome Activation via Elimination of Damaged Mitochondria
- (2016) Zhenyu Zhong et al. CELL
- TREM2-mediated early microglial response limits diffusion and toxicity of amyloid plaques
- (2016) Yaming Wang et al. JOURNAL OF EXPERIMENTAL MEDICINE
- Efficient derivation of microglia-like cells from human pluripotent stem cells
- (2016) Julien Muffat et al. NATURE MEDICINE
- Microglial brain region−dependent diversity and selective regional sensitivities to aging
- (2016) Kathleen Grabert et al. NATURE NEUROSCIENCE
- A polarizing question: do M1 and M2 microglia exist?
- (2016) Richard M Ransohoff NATURE NEUROSCIENCE
- TREM2 Haplodeficiency in Mice and Humans Impairs the Microglia Barrier Function Leading to Decreased Amyloid Compaction and Severe Axonal Dystrophy
- (2016) Peng Yuan et al. NEURON
- GLP-1 is both anxiogenic and antidepressant; divergent effects of acute and chronic GLP-1 on emotionality
- (2016) Rozita H Anderberg et al. PSYCHONEUROENDOCRINOLOGY
- Pathological -synuclein transmission initiated by binding lymphocyte-activation gene 3
- (2016) X. Mao et al. SCIENCE
- Microglia protect against brain injury and their selective elimination dysregulates neuronal network activity after stroke
- (2016) Gergely Szalay et al. Nature Communications
- TREM2 Lipid Sensing Sustains the Microglial Response in an Alzheimer’s Disease Model
- (2015) Yaming Wang et al. CELL
- Parkinson risk in idiopathic REM sleep behavior disorder: Preparing for neuroprotective trials
- (2015) R. B. Postuma et al. NEUROLOGY
- The Roles of PINK1, Parkin, and Mitochondrial Fidelity in Parkinson’s Disease
- (2015) Alicia M. Pickrell et al. NEURON
- Dysregulation of astrocyte extracellular signaling in Costello syndrome
- (2015) Robert Krencik et al. Science Translational Medicine
- Direct evidence of Parkinson pathology spread from the gastrointestinal tract to the brain in rats
- (2014) Staffan Holmqvist et al. ACTA NEUROPATHOLOGICA
- Macrophage Activation and Polarization: Nomenclature and Experimental Guidelines
- (2014) Peter J. Murray et al. IMMUNITY
- The prevalence of Parkinson's disease: A systematic review and meta-analysis
- (2014) Tamara Pringsheim et al. MOVEMENT DISORDERS
- Addition of exogenous α-synuclein preformed fibrils to primary neuronal cultures to seed recruitment of endogenous α-synuclein to Lewy body and Lewy neurite–like aggregates
- (2014) Laura A Volpicelli-Daley et al. Nature Protocols
- Colony-Stimulating Factor 1 Receptor Signaling Is Necessary for Microglia Viability, Unmasking a Microglia Progenitor Cell in the Adult Brain
- (2014) Monica R.P. Elmore et al. NEURON
- The Cajal school and the physiological role of astrocytes: a way of thinking
- (2014) Marta Navarrete Frontiers in Neuroanatomy
- Association of Parkinson Disease with Structural and Regulatory Variants in the HLA Region
- (2013) William T. Wissemann et al. AMERICAN JOURNAL OF HUMAN GENETICS
- The Hallmarks of Aging
- (2013) Carlos López-Otín et al. CELL
- MHCII Is Required for -Synuclein-Induced Activation of Microglia, CD4 T Cell Proliferation, and Dopaminergic Neurodegeneration
- (2013) A. S. Harms et al. JOURNAL OF NEUROSCIENCE
- Landscape of the PARKIN-dependent ubiquitylome in response to mitochondrial depolarization
- (2013) Shireen A. Sarraf et al. NATURE
- TREM2 and Neurodegenerative Disease
- (2013) NEW ENGLAND JOURNAL OF MEDICINE
- Neuron-released oligomeric α-synuclein is an endogenous agonist of TLR2 for paracrine activation of microglia
- (2013) Changyoun Kim et al. Nature Communications
- Noninvasive Molecular Imaging of Neuroinflammation
- (2012) Andreas H Jacobs et al. JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM
- Genomic Analysis of Reactive Astrogliosis
- (2012) J. L. Zamanian et al. JOURNAL OF NEUROSCIENCE
- Astrocyte glypicans 4 and 6 promote formation of excitatory synapses via GluA1 AMPA receptors
- (2012) Nicola J. Allen et al. NATURE
- Variant of TREM2 Associated with the Risk of Alzheimer's Disease
- (2012) Thorlakur Jonsson et al. NEW ENGLAND JOURNAL OF MEDICINE
- TREM2 Variants in Alzheimer's Disease
- (2012) Rita Guerreiro et al. NEW ENGLAND JOURNAL OF MEDICINE
- Pathological -Synuclein Transmission Initiates Parkinson-like Neurodegeneration in Nontransgenic Mice
- (2012) K. C. Luk et al. SCIENCE
- Direct Transfer of α-Synuclein from Neuron to Astroglia Causes Inflammatory Responses in Synucleinopathies
- (2010) He-Jin Lee et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- The role of parkin in familial and sporadic Parkinson's disease
- (2010) Ted M. Dawson et al. MOVEMENT DISORDERS
- Fate Mapping Analysis Reveals That Adult Microglia Derive from Primitive Macrophages
- (2010) F. Ginhoux et al. SCIENCE
- Incretin-based therapies for type 2 diabetes mellitus
- (2009) Julie A. Lovshin et al. Nature Reviews Endocrinology
- GLP-1 receptor stimulation preserves primary cortical and dopaminergic neurons in cellular and rodent models of stroke and Parkinsonism
- (2009) Y. Li et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Glucagon-like peptide 1 receptor stimulation by exendin-4 reverses key deficits in distinct rodent models of Parkinson's disease
- (2008) Alexander Harkavyi et al. Journal of Neuroinflammation
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