The Role of Tissue Resident Memory CD4 T Cells in Herpes Simplex Viral and HIV Infection

Developmental plasticity allows outside-in immune responses by resident memory T cells

(2020) Raissa Fonseca et al.   NATURE IMMUNOLOGY

Diverse effects of interferon alpha on the establishment and reversal of HIV latency

(2020) Renée M. Van der Sluis et al.   PLoS Pathogens

Herpes simplex virus: global infection prevalence and incidence estimates, 2016

(2020) Charlotte James et al.   BULLETIN OF THE WORLD HEALTH ORGANIZATION

Integrating resident memory into T cell differentiation models

(2020) Pamela C Rosato et al.   CURRENT OPINION IN IMMUNOLOGY

Tissue-resident T cell–derived cytokines eliminate herpes simplex virus-2–infected cells

(2020) Pavitra Roychoudhury et al.   JOURNAL OF CLINICAL INVESTIGATION

Cutting Edge: Characterization of Human Tissue-Resident Memory T Cells at Different Infection Sites in Patients with Tuberculosis

(2020) Qianting Yang et al.   JOURNAL OF IMMUNOLOGY

Th22 cells are efficiently recruited in the gut by CCL28 as an alternative to CCL20 but do not compensate for the loss of Th17 cells in treated HIV-1-infected individuals

(2020) Manon Nayrac et al.   Mucosal Immunology

T cell-inducing vaccine durably prevents mucosal SHIV infection even with lower neutralizing antibody titers

(2020) Prabhu S. Arunachalam et al.   NATURE MEDICINE

TRM integrins CD103 and CD49a differentially support adherence and motility after resolution of influenza virus infection

(2020) Emma C. Reilly et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

HIV efficiently infects T cells from the endometrium and remodels them to promote systemic viral spread

(2020) Tongcui Ma et al.   eLife

Early precursors and molecular determinants of tissue-resident memory CD8+ T lymphocytes revealed by single-cell RNA sequencing

(2020) Nadia S. Kurd et al.   Science Immunology

Retrograde migration supplies resident memory T cells to lung-draining LN after influenza infection

(2020) J. Michael Stolley et al.   JOURNAL OF EXPERIMENTAL MEDICINE

IL-21 in Homeostasis of Resident Memory and Exhausted CD8 T Cells during Persistent Infection

(2020) Heather M. Ren et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Phenotypic analysis of the unstimulated in vivo HIV CD4 T cell reservoir

(2020) Jason Neidleman et al.   eLife

IL-21 from high-affinity CD4 T cells drives differentiation of brain-resident CD8 T cells during persistent viral infection

(2020) Heather M. Ren et al.   Science Immunology

Impact of HIV-ART on the restoration of Th17 and Treg cells in blood and female genital mucosa

(2019) María Paula Caruso et al.   Scientific Reports

Increase of CXCR3+ T cells impairs Th17 cells recruitment in the small intestine mucosa through IFN-γ and IL-18 during treated HIV-1 infection

(2019) C Loiseau et al.   JOURNAL OF INFECTIOUS DISEASES

CD4+ resident memory T cells dominate immunosurveillance and orchestrate local recall responses

(2019) Lalit K. Beura et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Origins of CD 4 + circulating and tissue‐resident memory T cells

(2019) Quynh P. Nguyen et al.   IMMUNOLOGY

Characterization of CD4 + T cell subsets and HIV susceptibility in the inner and outer foreskin of Ugandan men

(2019) Ronald Moses Galiwango et al.   AMERICAN JOURNAL OF REPRODUCTIVE IMMUNOLOGY

Editorial: Tissue Resident Memory T Cells

(2019) Fathia Mami-Chouaib et al.   Frontiers in Immunology

Human CD4+CD103+ cutaneous resident memory T cells are found in the circulation of healthy individuals

(2019) Maria M. Klicznik et al.   Science Immunology

CXCR6 regulates localization of tissue-resident memory CD8 T cells to the airways

(2019) Alexander N. Wein et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Global and regional estimates of the contribution of herpes simplex virus type 2 infection to HIV incidence: a population attributable fraction analysis using published epidemiological data

(2019) Katharine J Looker et al.   LANCET INFECTIOUS DISEASES

Resident memory T cells are a cellular reservoir for HIV in the cervical mucosa

(2019) Jon Cantero-Pérez et al.   Nature Communications

Single-cell transcriptomics of human T cells reveals tissue and activation signatures in health and disease

(2019) Peter A. Szabo et al.   Nature Communications

Critical role of interleukin (IL)-17 in inflammatory and immune disorders: An updated review of the evidence focusing in controversies

(2019) José María G. Ruiz de Morales et al.   AUTOIMMUNITY REVIEWS

Corneal regeneration: A review of stromal replacements

(2018) Steffi Matthyssen et al.   Acta Biomaterialia

Human T Cell Development, Localization, and Function throughout Life

(2018) Brahma V. Kumar et al.   IMMUNITY

Understanding Subset Diversity in T Cell Memory

(2018) Stephen C. Jameson et al.   IMMUNITY

Altered Ratio of T Follicular Helper Cells to T Follicular Regulatory Cells Correlates with Autoreactive Antibody Response in Simian Immunodeficiency Virus–Infected Rhesus Macaques

(2018) Wenjin Fan et al.   JOURNAL OF IMMUNOLOGY

Application of our understanding of pathogenesis of herpetic stromal keratitis for novel therapy

(2018) Naveen K. Rajasagi et al.   MICROBES AND INFECTION

Rapid HIV RNA rebound after antiretroviral treatment interruption in persons durably suppressed in Fiebig I acute HIV infection

(2018) Donn J. Colby et al.   NATURE MEDICINE

Immunology of the Uterine and Vaginal Mucosae

(2018) Jordan Z. Zhou et al.   TRENDS IN IMMUNOLOGY

A Fixed Spatial Structure of CD8+T Cells in Tissue during Chronic HSV-2 Infection

(2018) Joshua T. Schiffer et al.   JOURNAL OF IMMUNOLOGY

Combination therapy with anti-HIV-1 antibodies maintains viral suppression

(2018) Pilar Mendoza et al.   NATURE

Development of Inflammatory Hypoxia and Prevalence of Glycolytic Metabolism in Progressing Herpes Stromal Keratitis Lesions

(2018) Pushpa Rao et al.   JOURNAL OF IMMUNOLOGY

Characterization of the Genital Mucosa Immune Profile to Distinguish Phases of the Menstrual Cycle: Implications for HIV Susceptibility

(2018) Geneviève Boily-Larouche et al.   JOURNAL OF INFECTIOUS DISEASES

Herpes Simplex Virus 1 ICP22 Suppresses CD80 Expression by Murine Dendritic Cells

(2018) Harry Matundan et al.   JOURNAL OF VIROLOGY

Pathogenesis of herpes simplex keratitis: The host cell response and ocular surface sequelae to infection and inflammation

(2018) Ann-Marie Lobo et al.   Ocular Surface

Tissue-resident memory T cells populate the human brain

(2018) Joost Smolders et al.   Nature Communications

Herpes Simplex Virus Type 2 Infection-Induced Expression of CXCR3 Ligands Promotes CD4+ T Cell Migration and Is Regulated by the Viral Immediate-Early Protein ICP4

(2018) Mudan Zhang et al.   Frontiers in Immunology

Role of Herpes Simplex Virus Type 1 (HSV-1) Glycoprotein K (gK) Pathogenic CD8+ T Cells in Exacerbation of Eye Disease

(2018) Ujjaldeep Jaggi et al.   Frontiers in Immunology

CTLA-4 + PD-1 − Memory CD4 + T Cells Critically Contribute to Viral Persistence in Antiretroviral Therapy-Suppressed, SIV-Infected Rhesus Macaques

(2017) Colleen S. McGary et al.   IMMUNITY

Clonal expansion of genome-intact HIV-1 in functionally polarized Th1 CD4+ T cells

(2017) Guinevere Q. Lee et al.   JOURNAL OF CLINICAL INVESTIGATION

Bolstering the Number and Function of HSV-1–Specific CD8+Effector Memory T Cells and Tissue-Resident Memory T Cells in Latently Infected Trigeminal Ganglia Reduces Recurrent Ocular Herpes Infection and Disease

(2017) Arif A. Khan et al.   JOURNAL OF IMMUNOLOGY

Regulatory T Cells Contribute to HIV-1 Reservoir Persistence in CD4+ T Cells Through Cyclic Adenosine Monophosphate–Dependent Mechanisms in Humanized Mice In Vivo

(2017) Guangming Li et al.   JOURNAL OF INFECTIOUS DISEASES

Follicular Regulatory T Cells Are Highly Permissive to R5-Tropic HIV-1

(2017) Shannon M. Miller et al.   JOURNAL OF VIROLOGY

Effect of HSV-2 infection on subsequent HIV acquisition: an updated systematic review and meta-analysis

(2017) Katharine J Looker et al.   LANCET INFECTIOUS DISEASES

Detection of HIV-1-specific gastrointestinal tissue resident CD8+ T-cells in chronic infection

(2017) Brenna E Kiniry et al.   Mucosal Immunology

IL-15 supports the generation of protective lung-resident memory CD4 T cells

(2017) T M Strutt et al.   Mucosal Immunology

Enrichment of herpes simplex virus type 2 (HSV-2) reactive mucosal T cells in the human female genital tract

(2017) C M Posavad et al.   Mucosal Immunology

Trigger-happy resident memory CD4+ T cells inhabit the human lungs

(2017) A E Oja et al.   Mucosal Immunology

Runx3 programs CD8+ T cell residency in non-lymphoid tissues and tumours

(2017) J. Justin Milner et al.   NATURE

The Mechanisms of T Cell Selection in the Thymus

(2017) Hiroyuki Takaba et al.   TRENDS IN IMMUNOLOGY

Unique phenotypes and clonal expansions of human CD4 effector memory T cells re-expressing CD45RA

(2017) Yuan Tian et al.   Nature Communications

Local Inflammatory Cues Regulate Differentiation and Persistence of CD8 + Tissue-Resident Memory T Cells

(2017) Tessa Bergsbaken et al.   Cell Reports

Identification of Genetically Intact HIV-1 Proviruses in Specific CD4 + T Cells from Effectively Treated Participants

(2017) Bonnie Hiener et al.   Cell Reports

Human Tissue-Resident Memory T Cells Are Defined by Core Transcriptional and Functional Signatures in Lymphoid and Mucosal Sites

(2017) Brahma V. Kumar et al.   Cell Reports

The Human Penis Is a Genuine Immunological Effector Site

(2017) Alexis Sennepin et al.   Frontiers in Immunology

HIV-1 and SIV Predominantly Use CCR5 Expressed on a Precursor Population to Establish Infection in T Follicular Helper Cells

(2017) Yin Xu et al.   Frontiers in Immunology

Cultured corneas show dendritic spread and restrict herpes simplex virus infection that is not observed with cultured corneal cells

(2017) Neel Thakkar et al.   Scientific Reports

Th17 Cells Are Preferentially Infected Very Early after Vaginal Transmission of SIV in Macaques

(2016) Daniel J. Stieh et al.   Cell Host & Microbe

A High-Dimensional Atlas of Human T Cell Diversity Reveals Tissue-Specific Trafficking and Cytokine Signatures

(2016) Michael Thomas Wong et al.   IMMUNITY

Progesterone Levels Associate with a Novel Population of CCR5+CD38+CD4 T Cells Resident in the Genital Mucosa with Lymphoid Trafficking Potential

(2016) Alison Swaims-Kohlmeier et al.   JOURNAL OF IMMUNOLOGY

CD8+T Cells Play a Bystander Role in Mice Latently Infected with Herpes Simplex Virus 1

(2016) Kevin R. Mott et al.   JOURNAL OF VIROLOGY

Human Th17 Cells Lack HIV-Inhibitory RNases and Are Highly Permissive to Productive HIV Infection

(2016) Aaron Christensen-Quick et al.   JOURNAL OF VIROLOGY

CCR6− regulatory T cells blunt the restoration of gut Th17 cells along the CCR6–CCL20 axis in treated HIV-1-infected individuals

(2016) C Loiseau et al.   Mucosal Immunology

Differentiation of distinct long-lived memory CD4 T cells in intestinal tissues after oral Listeria monocytogenes infection

(2016) P A Romagnoli et al.   Mucosal Immunology

A single injection of anti-HIV-1 antibodies protects against repeated SHIV challenges

(2016) Rajeev Gautam et al.   NATURE

Defective proviruses rapidly accumulate during acute HIV-1 infection

(2016) Katherine M Bruner et al.   NATURE MEDICINE

PD-1+ and follicular helper T cells are responsible for persistent HIV-1 transcription in treated aviremic individuals

(2016) Riddhima Banga et al.   NATURE MEDICINE

Effect of HIV Antibody VRC01 on Viral Rebound after Treatment Interruption

(2016) Katharine J. Bar et al.   NEW ENGLAND JOURNAL OF MEDICINE

Hobit and Blimp1 instruct a universal transcriptional program of tissue residency in lymphocytes

(2016) L. K. Mackay et al.   SCIENCE

Skin CD4+ memory T cells exhibit combined cluster-mediated retention and equilibration with the circulation

(2016) Nicholas Collins et al.   Nature Communications

Genital inflammation, immune activation and risk of sexual HIV acquisition

(2016) Jo-Ann S. Passmore et al.   Current Opinion in HIV and AIDS

Persistent HIV-1 replication during antiretroviral therapy

(2016) Javier Martinez-Picado et al.   Current Opinion in HIV and AIDS

Loss of Function of Intestinal IL-17 and IL-22 Producing Cells Contributes to Inflammation and Viral Persistence in SIV-Infected Rhesus Macaques

(2016) Emily S. Ryan et al.   PLoS Pathogens

Changes in the contribution of genital tract infections to HIV acquisition among Kenyan high-risk women from 1993 to 2012

(2015) Linnet Masese et al.   AIDS

Interleukin-22: Immunobiology and Pathology

(2015) Jarrod A. Dudakov et al.   Annual Review of Immunology

Th9 Cells: A Novel CD4 T-cell Subset in the Immune War against Cancer

(2015) F. Vegran et al.   CANCER RESEARCH

T-box Transcription Factors Combine with the Cytokines TGF-β and IL-15 to Control Tissue-Resident Memory T Cell Fate

(2015) Laura K. Mackay et al.   IMMUNITY

Relationship between female genital tract infections, mucosal interleukin-17 production and local T helper type 17 cells

(2015) Lindi Masson et al.   IMMUNOLOGY

CD4+CD25+CD127 regulatory cells play multiple roles in maintaining HIV-1 p24 production in patients on long-term treatment: HIV-1 p24-producing cells and suppression of anti-HIV immunity

(2015) Yan-Mei Jiao et al.   INTERNATIONAL JOURNAL OF INFECTIOUS DISEASES

Early HIV-1 Infection Is Associated With Reduced Frequencies of Cervical Th17 Cells

(2015) Lyle R. McKinnon et al.   JAIDS-JOURNAL OF ACQUIRED IMMUNE DEFICIENCY SYNDROMES

Herpes Simplex Virus Type 2–Infected Dendritic Cells Produce TNF-α, Which Enhances CCR5 Expression and Stimulates HIV Production from Adjacent Infected Cells

(2015) Valerie Marsden et al.   JOURNAL OF IMMUNOLOGY

Peripheral Blood–Derived Virus-Specific Memory Stem T Cells Mature to Functional Effector Memory Subsets with Self-Renewal Potency

(2015) Michael Schmueck-Henneresse et al.   JOURNAL OF IMMUNOLOGY

Regulatory and Helper Follicular T Cells and Antibody Avidity to Simian Immunodeficiency Virus Glycoprotein 120

(2015) Matthew J. Blackburn et al.   JOURNAL OF IMMUNOLOGY

Decreased T Follicular Regulatory Cell/T Follicular Helper Cell (TFH) in Simian Immunodeficiency Virus–Infected Rhesus Macaques May Contribute to Accumulation of TFHin Chronic Infection

(2015) Ankita Chowdhury et al.   JOURNAL OF IMMUNOLOGY

Cutting Edge: CD69 Interference with Sphingosine-1-Phosphate Receptor Function Regulates Peripheral T Cell Retention

(2015) Laura K. Mackay et al.   JOURNAL OF IMMUNOLOGY

Phenotypic and Functional Characterization of Herpes Simplex Virus Glycoprotein B Epitope-Specific Effector and Memory CD8+T Cells from Symptomatic and Asymptomatic Individuals with Ocular Herpes

(2015) Arif A. Khan et al.   JOURNAL OF VIROLOGY

Persistent Simian Immunodeficiency Virus Infection Drives Differentiation, Aberrant Accumulation, and Latent Infection of Germinal Center Follicular T Helper Cells

(2015) Huanbin Xu et al.   JOURNAL OF VIROLOGY

Identification of preferential CD4+ T-cell targets for HIV infection in the cervix

(2015) V R Joag et al.   Mucosal Immunology

Proinflammatory microenvironments within the intestine regulate the differentiation of tissue-resident CD8+ T cells responding to infection

(2015) Tessa Bergsbaken et al.   NATURE IMMUNOLOGY

Hair follicle–derived IL-7 and IL-15 mediate skin-resident memory T cell homeostasis and lymphoma

(2015) Takeya Adachi et al.   NATURE MEDICINE

B cell follicle sanctuary permits persistent productive simian immunodeficiency virus infection in elite controllers

(2015) Yoshinori Fukazawa et al.   NATURE MEDICINE

A Dual Role for Corneal Dendritic Cells in Herpes Simplex Keratitis: Local Suppression of Corneal Damage and Promotion of Systemic Viral Dissemination

(2015) Kai Hu et al.   PLoS One

Human skin is protected by four functionally and phenotypically discrete populations of resident and recirculating memory T cells

(2015) Rei Watanabe et al.   Science Translational Medicine

Tissue instruction for migration and retention of TRM cells

(2015) Norifumi Iijima et al.   TRENDS IN IMMUNOLOGY

Follicular regulatory T cells impair follicular T helper cells in HIV and SIV infection

(2015) Brodie Miles et al.   Nature Communications

Relay of Herpes Simplex Virus between Langerhans Cells and Dermal Dendritic Cells in Human Skin

(2015) Min Kim et al.   PLoS Pathogens

T Memory Stem Cells and HIV: a Long-Term Relationship

(2015) Ann Chahroudi et al.   Current HIV/AIDS Reports

Spatial Map of Human T Cell Compartmentalization and Maintenance over Decades of Life

(2014) Joseph J.C. Thome et al.   CELL

Defining Th-cell subsets in a classical and tissue-specific manner: Examples from the skin

(2014) Stefanie Eyerich et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Cellular and extracellular matrix modulation of corneal stromal opacity

(2014) Andre A.M. Torricelli et al.   EXPERIMENTAL EYE RESEARCH

T Follicular Helper Cell Differentiation, Function, and Roles in Disease

(2014) Shane Crotty   IMMUNITY

Loss of Th22 Cells Is Associated With Increased Immune Activation and IDO-1 Activity in HIV-1 Infection

(2014) Emma E. Page et al.   JAIDS-JOURNAL OF ACQUIRED IMMUNE DEFICIENCY SYNDROMES

Follicular regulatory T cells control humoral autoimmunity via NFAT2-regulated CXCR5 expression

(2014) Martin Vaeth et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Passive transfer of modest titers of potent and broadly neutralizing anti-HIV monoclonal antibodies block SHIV infection in macaques

(2014) Masashi Shingai et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Cornea-Infiltrating and Lymph Node Dendritic Cells Contribute to CD4+T Cell Expansion after Herpes Simplex Virus-1 Ocular Infection

(2014) Kristine-Ann G. Buela et al.   JOURNAL OF IMMUNOLOGY

Inhibition of Two Temporal Phases of HIV-1 Transfer from Primary Langerhans Cells to T Cells: The Role of Langerin

(2014) Najla Nasr et al.   JOURNAL OF IMMUNOLOGY

Better Neutralization of Herpes Simplex Virus Type 1 (HSV-1) Than HSV-2 by Antibody From Recipients of GlaxoSmithKline HSV-2 Glycoprotein D2 Subunit Vaccine

(2014) Sita Awasthi et al.   JOURNAL OF INFECTIOUS DISEASES

Role of CD8+T Cells and Lymphoid Dendritic Cells in Protection from Ocular Herpes Simplex Virus 1 Challenge in Immunized Mice

(2014) Harry Matundan et al.   JOURNAL OF VIROLOGY

Quantitation of Replication-Competent HIV-1 in Populations of Resting CD4+ T Cells

(2014) N. Soriano-Sarabia et al.   JOURNAL OF VIROLOGY

Early initiation of combined antiretroviral therapy preserves immune function in the gut of HIV-infected patients

(2014) A Kök et al.   Mucosal Immunology

Molecular regulation of effector and memory T cell differentiation

(2014) John T Chang et al.   NATURE IMMUNOLOGY

HIV-1 persistence in CD4+ T cells with stem cell–like properties

(2014) Maria J Buzon et al.   NATURE MEDICINE

Eradicating HIV-1 infection: seeking to clear a persistent pathogen

(2014) Nancie M. Archin et al.   NATURE REVIEWS MICROBIOLOGY

Persistence of skin-resident memory T cells within an epidermal niche

(2014) A. Zaid et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

A local macrophage chemokine network sustains protective tissue-resident memory CD4 T cells

(2014) N. Iijima et al.   SCIENCE

Progressive contraction of the latent HIV reservoir around a core of less-differentiated CD4+ memory T Cells

(2014) S. Jaafoura et al.   Nature Communications

Ocular herpes: the pathophysiology, management and treatment of herpetic eye diseases

(2014) Lucy Zhu et al.   VIROLOGICA SINICA

Replication-Competent Noninduced Proviruses in the Latent Reservoir Increase Barrier to HIV-1 Cure

(2013) Ya-Chi Ho et al.   CELL

Transforming Growth Factor-β Signaling Controls the Formation and Maintenance of Gut-Resident Memory T Cells by Regulating Migration and Retention

(2013) Nu Zhang et al.   IMMUNITY

Systemic Effects of Inflammation on Health during Chronic HIV Infection

(2013) Steven G. Deeks et al.   IMMUNITY

Skin-resident memory T cells keep herpes simplex virus at bay

(2013) Thomas Gebhardt et al.   IMMUNOLOGY AND CELL BIOLOGY

Superior T memory stem cell persistence supports long-lived T cell memory

(2013) Enrico Lugli et al.   JOURNAL OF CLINICAL INVESTIGATION

Distinct Chemokine Receptor Axes Regulate Th9 Cell Trafficking to Allergic and Autoimmune Inflammatory Sites

(2013) E. E. Kara et al.   JOURNAL OF IMMUNOLOGY

Early Treatment and HIV-1 Reservoirs: A Stitch in Time?

(2013) Timothy J. Henrich et al.   JOURNAL OF INFECTIOUS DISEASES

The Distribution of HIV DNA and RNA in Cell Subsets Differs in Gut and Blood of HIV-Positive Patients on ART: Implications for Viral Persistence

(2013) Steven A. Yukl et al.   JOURNAL OF INFECTIOUS DISEASES

Immunological control of herpes simplex virus infections

(2013) Kevin P. Egan et al.   JOURNAL OF NEUROVIROLOGY

Preferential HIV Infection of CCR6+ Th17 Cells Is Associated with Higher Levels of Virus Receptor Expression and Lack of CCR5 Ligands

(2013) Y. Alvarez et al.   JOURNAL OF VIROLOGY

Simian Immunodeficiency Virus Infects Follicular Helper CD4 T Cells in Lymphoid Tissues during Pathogenic Infection of Pigtail Macaques

(2013) Y. Xu et al.   JOURNAL OF VIROLOGY

Immune surveillance by CD8αα+ skin-resident T cells in human herpes virus infection

(2013) Jia Zhu et al.   NATURE

Transcriptional downregulation of S1pr1 is required for the establishment of resident memory CD8+ T cells

(2013) Cara N Skon et al.   NATURE IMMUNOLOGY

Inadequate T follicular cell help impairs B cell immunity during HIV infection

(2013) Rafael A Cubas et al.   NATURE MEDICINE

Incomplete Normalization of Regulatory T-Cell Frequency in the Gut Mucosa of Colombian HIV-Infected Patients Receiving Long-Term Antiretroviral Treatment

(2013) Cesar M. Rueda et al.   PLoS One

Myeloid Dendritic Cells Induce HIV-1 Latency in Non-proliferating CD4+ T Cells

(2013) Vanessa A. Evans et al.   PLoS Pathogens

Local CD4 and CD8 T-Cell Reactivity to HSV-1 Antigens Documents Broad Viral Protein Expression and Immune Competence in Latently Infected Human Trigeminal Ganglia

(2013) Monique van Velzen et al.   PLoS Pathogens

Mucosal HSV-2 Specific CD8+ T-Cells Represent Containment of Prior Viral Shedding Rather than a Correlate of Future Protection

(2013) Joshua T. Schiffer   Frontiers in Immunology

Memory T Cell Subsets, Migration Patterns, and Tissue Residence

(2012) Scott N. Mueller et al.   Annual Review of Immunology

Distribution of Antigen Presenting Cells in the Human Cornea: Correlation of In Vivo Confocal Microscopy and Immunohistochemistry in Different Pathologic Entities

(2012) Wolfgang J. Mayer et al.   CURRENT EYE RESEARCH

Distribution and Compartmentalization of Human Circulating and Tissue-Resident Memory T Cell Subsets

(2012) Taheri Sathaliyawala et al.   IMMUNITY

Expansion of HIV-specific T follicular helper cells in chronic HIV infection

(2012) Madelene Lindqvist et al.   JOURNAL OF CLINICAL INVESTIGATION

Follicular helper T cells serve as the major CD4 T cell compartment for HIV-1 infection, replication, and production

(2012) Matthieu Perreau et al.   JOURNAL OF EXPERIMENTAL MEDICINE

On the Role of Regulatory T Cells during Viral-Induced Inflammatory Lesions

(2012) T. Veiga-Parga et al.   JOURNAL OF IMMUNOLOGY

Antigen-Independent Differentiation and Maintenance of Effector-like Resident Memory T Cells in Tissues

(2012) K. A. Casey et al.   JOURNAL OF IMMUNOLOGY

Herpes Simplex Virus 2 (HSV-2) Prevents Dendritic Cell Maturation, Induces Apoptosis, and Triggers Release of Proinflammatory Cytokines: Potential Links to HSV-HIV Synergy

(2012) Martha Stefanidou et al.   JOURNAL OF VIROLOGY

A role for mucosal IL-22 production and Th22 cells in HIV-associated mucosal immunopathogenesis

(2012) C J Kim et al.   Mucosal Immunology

Functional diversity of human vaginal APC subsets in directing T-cell responses

(2012) D Duluc et al.   Mucosal Immunology

A vaccine strategy that protects against genital herpes by establishing local memory T cells

(2012) Haina Shin et al.   NATURE

Microbial translocation in HIV infection: causes, consequences and treatment opportunities

(2012) Netanya G. Sandler et al.   NATURE REVIEWS MICROBIOLOGY

Efficacy Results of a Trial of a Herpes Simplex Vaccine

(2012) Robert B. Belshe et al.   NEW ENGLAND JOURNAL OF MEDICINE

Pathogenesis of herpes stromal keratitis – A focus on corneal neovascularization

(2012) Fernanda Giménez et al.   PROGRESS IN RETINAL AND EYE RESEARCH

Herpes keratitis

(2012) A.M. Rowe et al.   PROGRESS IN RETINAL AND EYE RESEARCH

Herpes Simplex Epithelial and Stromal Keratitis: An Epidemiologic Update

(2012) Asim V. Farooq et al.   SURVEY OF OPHTHALMOLOGY

Sigmoid Th17 populations, the HIV latent reservoir, and microbial translocation in men on long-term antiretroviral therapy

(2011) Duncan Chege et al.   AIDS

Mechanisms of Leukocyte Transendothelial Migration

(2011) William A. Muller   Annual Review of Pathology-Mechanisms of Disease

Ocular herpes simplex virus: how are latency, reactivation, recurrent disease and therapy interrelated?

(2011) Lena J Al-Dujaili et al.   Future Microbiology

CXCR6 Is a Marker for Protective Antigen-Specific Cells in the Lungs after Intranasal Immunization against Mycobacterium tuberculosis

(2011) Lian Ni Lee et al.   INFECTION AND IMMUNITY

Human Bone Marrow Hosts Polyfunctional Memory CD4+ and CD8+ T Cells with Close Contact to IL-15-Producing Cells

(2011) D. Herndler-Brandstetter et al.   JOURNAL OF IMMUNOLOGY

Early Responding Dendritic Cells Direct the Local NK Response To Control Herpes Simplex Virus 1 Infection within the Cornea

(2011) G. M. Frank et al.   JOURNAL OF IMMUNOLOGY

Characterization of a Human Cervical CD4+ T Cell Subset Coexpressing Multiple Markers of HIV Susceptibility

(2011) L. R. McKinnon et al.   JOURNAL OF IMMUNOLOGY

Role of IL-17 and Th17 Cells in Herpes Simplex Virus-Induced Corneal Immunopathology

(2011) A. Suryawanshi et al.   JOURNAL OF IMMUNOLOGY

Increased Frequency of Regulatory T Cells Accompanies Increased Immune Activation in Rectal Mucosae of HIV-Positive Noncontrollers

(2011) J. M. Shaw et al.   JOURNAL OF VIROLOGY

The role of interleukin-15 in inflammation and immune responses to infection: implications for its therapeutic use

(2011) Pin-Yu Perera et al.   MICROBES AND INFECTION

Different patterns of peripheral migration by memory CD4+ and CD8+ T cells

(2011) Thomas Gebhardt et al.   NATURE

Profound early control of highly pathogenic SIV by an effector memory T-cell vaccine

(2011) Scott G. Hansen et al.   NATURE

Mouse CCL8, a CCR8 agonist, promotes atopic dermatitis by recruiting IL-5+ TH2 cells

(2011) Sabina A Islam et al.   NATURE IMMUNOLOGY

Follicular regulatory T cells expressing Foxp3 and Bcl-6 suppress germinal center reactions

(2011) Yeonseok Chung et al.   NATURE MEDICINE

Foxp3+ follicular regulatory T cells control the germinal center response

(2011) Michelle A Linterman et al.   NATURE MEDICINE

A human memory T cell subset with stem cell–like properties

(2011) Luca Gattinoni et al.   NATURE MEDICINE

The Th1 life cycle: molecular control of IFN-γ to IL-10 switching

(2011) Andrew Cope et al.   TRENDS IN IMMUNOLOGY

The Molecular Mechanisms of Regulatory T Cell Immunosuppression

(2011) Pushpa Pandiyan et al.   Frontiers in Immunology

Interleukin-17 and its expanding biological functions

(2010) Sheng Xu et al.   Cellular & Molecular Immunology

Biological Determinants of Immune Reconstitution in HIV‐Infected Patients Receiving Antiretroviral Therapy: The Role of Interleukin 7 and Interleukin 7 Receptor α and Microbial Translocation

(2010) Reena Rajasuriar et al.   JOURNAL OF INFECTIOUS DISEASES

Nature, Position, and Frequency of Mutations Made in a Single Cycle of HIV-1 Replication

(2010) M. E. Abram et al.   JOURNAL OF VIROLOGY

Within 1 h, HIV-1 uses viral synapses to enter efficiently the inner, but not outer, foreskin mucosa and engages Langerhans–T cell conjugates

(2010) Y Ganor et al.   Mucosal Immunology

The transcription factor PU.1 is required for the development of IL-9-producing T cells and allergic inflammation

(2010) Hua-Chen Chang et al.   NATURE IMMUNOLOGY

Corneal Sensation and Subbasal Nerve Alterations in Patients with Herpes Simplex Keratitis

(2010) Pedram Hamrah et al.   OPHTHALMOLOGY

Analysis of CD161 expression on human CD8+ T cells defines a distinct functional subset with tissue-homing properties

(2010) E. Billerbeck et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Role of β7 Integrins in Intestinal Lymphocyte Homing and Retention

(2009) G. Gorfu et al.   CURRENT MOLECULAR MEDICINE

Macrophage- and Dendritic-Cell-Derived Interleukin-15 Receptor Alpha Supports Homeostasis of Distinct CD8+ T Cell Subsets

(2009) Erwan Mortier et al.   IMMUNITY

Peripheral Blood CCR4+CCR6+ and CXCR3+CCR6+ CD4+ T Cells Are Highly Permissive to HIV-1 Infection

(2009) A. Gosselin et al.   JOURNAL OF IMMUNOLOGY

CD8+ T lymphocyte mobilization to virus-infected tissue requires CD4+ T-cell help

(2009) Yusuke Nakanishi et al.   NATURE

Identification of a human helper T cell population that has abundant production of interleukin 22 and is distinct from TH-17, TH1 and TH2 cells

(2009) Sara Trifari et al.   NATURE IMMUNOLOGY

Memory T cells in nonlymphoid tissue that provide enhanced local immunity during infection with herpes simplex virus

(2009) Thomas Gebhardt et al.   NATURE IMMUNOLOGY

Production of interleukin 22 but not interleukin 17 by a subset of human skin-homing memory T cells

(2009) Thomas Duhen et al.   NATURE IMMUNOLOGY

Persistence of HIV-1 receptor–positive cells after HSV-2 reactivation is a potential mechanism for increased HIV-1 acquisition

(2009) Jia Zhu et al.   NATURE MEDICINE

HIV reservoir size and persistence are driven by T cell survival and homeostatic proliferation

(2009) Nicolas Chomont et al.   NATURE MEDICINE

Vaccination with ALVAC and AIDSVAX to Prevent HIV-1 Infection in Thailand

(2009) Supachai Rerks-Ngarm et al.   NEW ENGLAND JOURNAL OF MEDICINE

The role of the novel Th17 cytokine IL-26 in intestinal inflammation

(2008) J Dambacher et al.   GUT

Long-lived virus-reactive memory T cells generated from purified cytokine-secreting T helper type 1 and type 2 effectors

(2008) Max Löhning et al.   JOURNAL OF EXPERIMENTAL MEDICINE

In Vitro-Generated Antigen-Specific CD4+ CD25+ Foxp3+ Regulatory T Cells Control the Severity of Herpes Simplex Virus-Induced Ocular Immunoinflammatory Lesions

(2008) S. Sehrawat et al.   JOURNAL OF VIROLOGY

Noncytotoxic Lytic Granule-Mediated CD8+ T Cell Inhibition of HSV-1 Reactivation from Neuronal Latency

(2008) J. E. Knickelbein et al.   SCIENCE