T cell-inducing vaccine durably prevents mucosal SHIV infection even with lower neutralizing antibody titers

VH1-69 Utilizing Antibodies Are Capable of Mediating Non-neutralizing Fc-Mediated Effector Functions Against the Transmitted/Founder gp120

(2019) S. Abigail Smith et al.   Frontiers in Immunology

HIV-1 vaccination by needle-free oral injection induces strong mucosal immunity and protects against SHIV challenge

(2019) Andrew T. Jones et al.   Nature Communications

Virus-specific memory T cells populate tumors and can be repurposed for tumor immunotherapy

(2019) Pamela C. Rosato et al.   Nature Communications

Migrant memory B cells secrete luminal antibody in the vagina

(2019) Ji Eun Oh et al.   NATURE

A Meta-analysis of Passive Immunization Studies Shows that Serum-Neutralizing Antibody Titer Associates with Protection against SHIV Challenge

(2019) Amarendra Pegu et al.   Cell Host & Microbe

Strong TH1-biased CD4 T cell responses are associated with diminished SIV vaccine efficacy

(2019) Venkateswarlu Chamcha et al.   Science Translational Medicine

Combination therapy with anti-HIV-1 antibodies maintains viral suppression

(2018) Pilar Mendoza et al.   NATURE

Vaccine-Induced Protection from Homologous Tier 2 SHIV Challenge in Nonhuman Primates Depends on Serum-Neutralizing Antibody Titers

(2018) Matthias G. Pauthner et al.   IMMUNITY

Defensive Driving: Directing HIV-1 Vaccine-Induced Humoral Immunity to the Mucosa with Chemokine Adjuvants

(2018) Ebony N. Gary et al.   Journal of Immunology Research

Elicitation of Robust Tier 2 Neutralizing Antibody Responses in Nonhuman Primates by HIV Envelope Trimer Immunization Using Optimized Approaches

(2017) Matthias Pauthner et al.   IMMUNITY

Native-like Env trimers as a platform for HIV-1 vaccine design

(2017) Rogier W. Sanders et al.   IMMUNOLOGICAL REVIEWS

Simultaneous epitope and transcriptome measurement in single cells

(2017) Marlon Stoeckius et al.   NATURE METHODS

Single-cell RNA-seq reveals new types of human blood dendritic cells, monocytes, and progenitors

(2017) Alexandra-Chloé Villani et al.   SCIENCE

Virus-Like Particles Displaying Trimeric Simian Immunodeficiency Virus (SIV) Envelope gp160 Enhance the Breadth of DNA/Modified Vaccinia Virus Ankara SIV Vaccine-Induced Antibody Responses in Rhesus Macaques

(2016) Smita S. Iyer et al.   JOURNAL OF VIROLOGY

Adjuvanting a Simian Immunodeficiency Virus Vaccine with Toll-Like Receptor Ligands Encapsulated in Nanoparticles Induces Persistent Antibody Responses and Enhanced Protection in TRIM5α Restrictive Macaques

(2016) Sudhir Pai Kasturi et al.   JOURNAL OF VIROLOGY

A single injection of anti-HIV-1 antibodies protects against repeated SHIV challenges

(2016) Rajeev Gautam et al.   NATURE

Effect of HIV Antibody VRC01 on Viral Rebound after Treatment Interruption

(2016) Katharine J. Bar et al.   NEW ENGLAND JOURNAL OF MEDICINE

Envelope residue 375 substitutions in simian–human immunodeficiency viruses enhance CD4 binding and replication in rhesus macaques

(2016) Hui Li et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Broadly targeted CD8+ T cell responses restricted by major histocompatibility complex E

(2016) S. G. Hansen et al.   SCIENCE

Diversification in the HIV-1 Envelope Hyper-variable Domains V2, V4, and V5 and Higher Probability of Transmitted/Founder Envelope Glycosylation Favor the Development of Heterologous Neutralization Breadth

(2016) S. Abigail Smith et al.   PLoS Pathogens

Quantifying Memory CD8 T Cells Reveals Regionalization of Immunosurveillance

(2015) Elizabeth M. Steinert et al.   CELL

Magnitude and Kinetics of CD8 + T Cell Activation during Hyperacute HIV Infection Impact Viral Set Point

(2015) Zaza M. Ndhlovu et al.   IMMUNITY

Characterization and Implementation of a Diverse Simian Immunodeficiency Virus SIVsm Envelope Panel in the Assessment of Neutralizing Antibody Breadth Elicited in Rhesus Macaques by Multimodal Vaccines Expressing the SIVmac239 Envelope

(2015) Katie M. Kilgore et al.   JOURNAL OF VIROLOGY

Identification of potential HIV restriction factors by combining evolutionary genomic signatures with functional analyses

(2015) Paul J McLaren et al.   Retrovirology

HIV-1 neutralizing antibodies induced by native-like envelope trimers

(2015) R. W. Sanders et al.   SCIENCE

Passive transfer of modest titers of potent and broadly neutralizing anti-HIV monoclonal antibodies block SHIV infection in macaques

(2014) Masashi Shingai et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Vaccines that stimulate T cell immunity to HIV-1: the next step

(2014) Andrew J McMichael et al.   NATURE IMMUNOLOGY

Preferential infection of human Ad5-specific CD4 T cells by HIV in Ad5 naturally exposed and recombinant Ad5-HIV vaccinated individuals

(2014) Haitao Hu et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Activated CD4+CCR5+T cells in the rectum predict increased SIV acquisition in SIVGag/Tat-vaccinated rhesus macaques

(2014) Diane G. Carnathan et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Resident memory CD8 T cells trigger protective innate and adaptive immune responses

(2014) J. M. Schenkel et al.   SCIENCE

Induction of Potent and Long-Lived Antibody and Cellular Immune Responses in the Genitorectal Mucosa Could be the Critical Determinant of HIV Vaccine Efficacy

(2014) Nadia Chanzu et al.   Frontiers in Immunology

Preexisting High Frequencies of Memory CD8+ T Cells Favor Rapid Memory Differentiation and Preservation of Proliferative Potential upon Boosting

(2013) Kathryn A. Fraser et al.   IMMUNITY

Molecular signatures of antibody responses derived from a systems biology study of five human vaccines

(2013) Shuzhao Li et al.   NATURE IMMUNOLOGY

Sensing and alarm function of resident memory CD8+ T cells

(2013) Jason M Schenkel et al.   NATURE IMMUNOLOGY

The T-Cell Response to HIV

(2013) B. Walker et al.   Cold Spring Harbor Perspectives in Medicine

Viral Escape from Neutralizing Antibodies in Early Subtype A HIV-1 Infection Drives an Increase in Autologous Neutralization Breadth

(2013) Megan K. Murphy et al.   PLoS Pathogens

A Next-Generation Cleaved, Soluble HIV-1 Env Trimer, BG505 SOSIP.664 gp140, Expresses Multiple Epitopes for Broadly Neutralizing but Not Non-Neutralizing Antibodies

(2013) Rogier W. Sanders et al.   PLoS Pathogens

Association of HIV neutralizing antibody with lower viral load after treatment interruption in a prospective trial (A5170)

(2012) Robert McLinden et al.   AIDS

CD8+ T cells in preventing HIV infection and disease

(2012) Adrian B. McDermott et al.   AIDS

B-Lymphocyte Dysfunction in Chronic HIV-1 Infection Does Not Prevent Cross-Clade Neutralization Breadth

(2012) S. Boliar et al.   JOURNAL OF VIROLOGY

Vaccine-induced CD8+ T cells control AIDS virus replication

(2012) Philip A. Mudd et al.   NATURE

SAMHD1 restricts HIV-1 infection in resting CD4+ T cells

(2012) Hanna-Mari Baldauf et al.   NATURE MEDICINE

Profound early control of highly pathogenic SIV by an effector memory T-cell vaccine

(2011) Scott G. Hansen et al.   NATURE

Moving ahead an HIV vaccine: Use both arms to beat HIV

(2011) Bruce D Walker et al.   NATURE MEDICINE

Nonpathogenic Simian Immunodeficiency Virus Infection of Sooty Mangabeys Is Not Associated with High Levels of Autologous Neutralizing Antibodies

(2010) B. Li et al.   JOURNAL OF VIROLOGY

The B Cell Response Is Redundant and Highly Focused on V1V2 during Early Subtype C Infection in a Zambian Seroconverter

(2010) R. M. Lynch et al.   JOURNAL OF VIROLOGY

Subtype-specific conservation of isoleucine 309 in the envelope V3 domain is linked to immune evasion in subtype C HIV-1 infection

(2010) Rebecca M. Lynch et al.   VIROLOGY

Expression and processing of human immunodeficiency virus type 1 gp160 using the vesicular stomatitis virus New Jersey serotype vector system

(2009) K. Wu et al.   JOURNAL OF GENERAL VIROLOGY

The Yellow Fever Virus Vaccine Induces a Broad and Polyfunctional Human Memory CD8+ T Cell Response

(2009) R. S. Akondy et al.   JOURNAL OF IMMUNOLOGY

Vaccination with ALVAC and AIDSVAX to Prevent HIV-1 Infection in Thailand

(2009) Supachai Rerks-Ngarm et al.   NEW ENGLAND JOURNAL OF MEDICINE

Adenovirus vector vaccination induces expansion of memory CD4 T cells with a mucosal homing phenotype that are readily susceptible to HIV-1

(2009) A. Benlahrech et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Escape from Autologous Neutralizing Antibodies in Acute/Early Subtype C HIV-1 Infection Requires Multiple Pathways

(2009) Rong Rong et al.   PLoS Pathogens

Human Effector and Memory CD8+ T Cell Responses to Smallpox and Yellow Fever Vaccines

(2008) Joseph D. Miller et al.   IMMUNITY

Efficacy assessment of a cell-mediated immunity HIV-1 vaccine (the Step Study): a double-blind, randomised, placebo-controlled, test-of-concept trial

(2008) Susan P Buchbinder et al.   LANCET

Memory CD8 T-cell compartment grows in size with immunological experience

(2008) Vaiva Vezys et al.   NATURE