Immunological control of herpes simplex virus infections

Mutational Inactivation of Herpes Simplex Virus 1 MicroRNAs Identifies Viral mRNA Targets and Reveals Phenotypic Effects in Culture

(2013) O. Flores et al.   JOURNAL OF VIROLOGY

LAT Region Factors Mediating Differential Neuronal Tropism of HSV-1 and HSV-2 Do Not Act in Trans

(2013) Andrea S. Bertke et al.   PLoS One

Herpes simplex virus US3 tegument protein inhibits Toll-like receptor 2 signaling at or before TRAF6 ubiquitination

(2013) Jayita Sen et al.   VIROLOGY

Herpesvirus Transport to the Nervous System and Back Again

(2012) Gregory Smith   Annual Review of Microbiology

Future of an ‘asymptomatic’ T-cell epitope-based therapeutic herpes simplex vaccine

(2012) Xavier Dervillez et al.   Future Virology

Control of viral latency in neurons by axonal mTOR signaling and the 4E-BP translation repressor

(2012) M. Kobayashi et al.   GENES & DEVELOPMENT

HeterozygousTBK1mutations impair TLR3 immunity and underlie herpes simplex encephalitis of childhood

(2012) Melina Herman et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Antigen-Independent Differentiation and Maintenance of Effector-like Resident Memory T Cells in Tissues

(2012) K. A. Casey et al.   JOURNAL OF IMMUNOLOGY

The Molecular Signature of Tissue Resident Memory CD8 T Cells Isolated from the Brain

(2012) L. M. Wakim et al.   JOURNAL OF IMMUNOLOGY

Herpes Simplex Virus Antigens Directly Activate NK Cells via TLR2, Thus Facilitating Their Presentation to CD4 T Lymphocytes

(2012) M. Kim et al.   JOURNAL OF IMMUNOLOGY

Resistance to HSV-1 infection in the epithelium resides with the novel innate sensor, IFI-16

(2012) C D Conrady et al.   Mucosal Immunology

A vaccine strategy that protects against genital herpes by establishing local memory T cells

(2012) Haina Shin et al.   NATURE

Induction of apoptosis accelerates reactivation of latent HSV-1 in ganglionic organ cultures and replication in cell cultures

(2012) T. Du et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Long-lived epithelial immunity by tissue-resident memory T (TRM) cells in the absence of persisting local antigen presentation

(2012) L. K. Mackay et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Transient Reversal of Episome Silencing Precedes VP16-Dependent Transcription during Reactivation of Latent HSV-1 in Neurons

(2012) Ju Youn Kim et al.   PLoS Pathogens

The role of the proteasome in the generation of MHC class I ligands and immune responses

(2011) E. J. A. M. Sijts et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Herpes simplex virus encephalitis in a patient with complete TLR3 deficiency: TLR3 is otherwise redundant in protective immunity

(2011) Yiqi Guo et al.   JOURNAL OF EXPERIMENTAL MEDICINE

The herpes simplex virus type 1 latency associated transcript locus is required for the maintenance of reactivation competent latent infections

(2011) Richard L. Thompson et al.   JOURNAL OF NEUROVIROLOGY

Checkpoints in productive and latent infections with herpes simplex virus 1: conceptualization of the issues

(2011) Bernard Roizman et al.   JOURNAL OF NEUROVIROLOGY

A5-Positive Primary Sensory Neurons Are Nonpermissive for Productive Infection with Herpes Simplex Virus 1 In Vitro

(2011) A. S. Bertke et al.   JOURNAL OF VIROLOGY

The Herpes Simplex Virus 1 Latency-Associated Transcript Promotes Functional Exhaustion of Virus-Specific CD8+ T Cells in Latently Infected Trigeminal Ganglia: a Novel Immune Evasion Mechanism

(2011) A. A. Chentoufi et al.   JOURNAL OF VIROLOGY

Entry Pathways of Herpes Simplex Virus Type 1 into Human Keratinocytes Are Dynamin- and Cholesterol-Dependent

(2011) Elena Rahn et al.   PLoS One

Sensing herpes: more than toll

(2011) Jesper Melchjorsen   REVIEWS IN MEDICAL VIROLOGY

Viruses, microRNAs, and Host Interactions

(2010) Rebecca L. Skalsky et al.   Annual Review of Microbiology

Apoptosis induction after herpes simplex virus infection differs according to cell type in vivo

(2010) Shinichi Esaki et al.   ARCHIVES OF VIROLOGY

Epigenetic regulation of latent HSV-1 gene expression

(2010) David C. Bloom et al.   Biochimica et Biophysica Acta-Gene Regulatory Mechanisms

Nature and Duration of Growth Factor Signaling through Receptor Tyrosine Kinases Regulates HSV-1 Latency in Neurons

(2010) Vladimir Camarena et al.   Cell Host & Microbe

Viral miRNAs: tools for immune evasion

(2010) Isaac W Boss et al.   CURRENT OPINION IN MICROBIOLOGY

Dynamic T cell migration program provides resident memory within intestinal epithelium

(2010) David Masopust et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Cathepsins are involved in virus-induced cell death in ICP4 and Us3 deletion mutant herpes simplex virus type 1-infected monocytic cells

(2010) P. Peri et al.   JOURNAL OF GENERAL VIROLOGY

Stress-Induced Glucocorticoids at the Earliest Stages of Herpes Simplex Virus-1 Infection Suppress Subsequent Antiviral Immunity, Implicating Impaired Dendritic Cell Function

(2010) Michael D. Elftman et al.   JOURNAL OF IMMUNOLOGY

Identification of herpes simplex virus type 1 proteins encoded within the first 1.5 kb of the latency-associated transcript

(2010) Gail Henderson et al.   JOURNAL OF NEUROVIROLOGY

Intravaginal infection with herpes simplex virus type-2 (HSV-2) generates a functional effector memory T cell population that persists in the murine genital tract

(2010) Vera A. Tang et al.   JOURNAL OF REPRODUCTIVE IMMUNOLOGY

Delaying the Expression of Herpes Simplex Virus Type 1 Glycoprotein B (gB) to a True Late Gene Alters Neurovirulence and Inhibits the gB-CD8+ T-Cell Response in the Trigeminal Ganglion

(2010) S. Ramachandran et al.   JOURNAL OF VIROLOGY

Murine Cytomegalovirus Perturbs Endosomal Trafficking of Major Histocompatibility Complex Class I Molecules in the Early Phase of Infection

(2010) M. I. Tomas et al.   JOURNAL OF VIROLOGY

The Herpes Simplex Virus Type 1 Latency-Associated Transcript Can Protect Neuron-Derived C1300 and Neuro2A Cells from Granzyme B-Induced Apoptosis and CD8 T-Cell Killing

(2010) X. Jiang et al.   JOURNAL OF VIROLOGY

Decline in Varicella-Related Ambulatory Visits and Hospitalizations in the United States Since Routine Immunization Against Varicella

(2010) Samir S. Shah et al.   PEDIATRIC INFECTIOUS DISEASE JOURNAL

ATM signals to TSC2 in the cytoplasm to regulate mTORC1 in response to ROS

(2010) A. Alexander et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Memory T cells persisting within the brain after local infection show functional adaptations to their tissue of residence

(2010) L. M. Wakim et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

A role for heparan sulfate in viral surfing

(2009) Myung-Jin Oh et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Psychological stress suppresses innate IFN-γ production via glucocorticoid receptor activation: Reversal by the anxiolytic chlordiazepoxide

(2009) Niamh M. Curtin et al.   BRAIN BEHAVIOR AND IMMUNITY

Regulation of major histocompatibility complex class II gene expression, genetic variation and disease

(2009) L Handunnetthi et al.   GENES AND IMMUNITY

Recognition of 5′ Triphosphate by RIG-I Helicase Requires Short Blunt Double-Stranded RNA as Contained in Panhandle of Negative-Strand Virus

(2009) Martin Schlee et al.   IMMUNITY

Herpes simplex virus type 1 latency-associated transcript inhibits apoptosis and promotes neurite sprouting in neuroblastoma cells following serum starvation by maintaining protein kinase B (AKT) levels

(2009) S. Li et al.   JOURNAL OF GENERAL VIROLOGY

Dendritic Cells Are Required for Optimal Activation of Natural Killer Functions following Primary Infection with Herpes Simplex Virus Type 1

(2009) S. H. Kassim et al.   JOURNAL OF VIROLOGY

Herpes Simplex Virus Type 1 (HSV-1)-Induced Apoptosis in Human Dendritic Cells as a Result of Downregulation of Cellular FLICE-Inhibitory Protein and Reduced Expression of HSV-1 Antiapoptotic Latency-Associated Transcript Sequences

(2009) A. Kather et al.   JOURNAL OF VIROLOGY

Transcription of the Herpes Simplex Virus Latency-Associated Transcript Promotes the Formation of Facultative Heterochromatin on Lytic Promoters

(2009) A. R. Cliffe et al.   JOURNAL OF VIROLOGY

Two Small RNAs Encoded within the First 1.5 Kilobases of the Herpes Simplex Virus Type 1 Latency-Associated Transcript Can Inhibit Productive Infection and Cooperate To Inhibit Apoptosis

(2009) W. Shen et al.   JOURNAL OF VIROLOGY

Activation of MDA5 Requires Higher-Order RNA Structures Generated during Virus Infection

(2009) A. Pichlmair et al.   JOURNAL OF VIROLOGY

Analysis of Human Alphaherpesvirus MicroRNA Expression in Latently Infected Human Trigeminal Ganglia

(2009) J. L. Umbach et al.   JOURNAL OF VIROLOGY

Memory T cells in nonlymphoid tissue that provide enhanced local immunity during infection with herpes simplex virus

(2009) Thomas Gebhardt et al.   NATURE IMMUNOLOGY

Involvement of gD/HVEM interaction in NF-kB-dependent inhibition of apoptosis by HSV-1 gD

(2008) Maria Teresa Sciortino et al.   BIOCHEMICAL PHARMACOLOGY

PILRα Is a Herpes Simplex Virus-1 Entry Coreceptor That Associates with Glycoprotein B

(2008) Takeshi Satoh et al.   CELL

Viral and Cellular MicroRNAs as Determinants of Viral Pathogenesis and Immunity

(2008) Eva Gottwein et al.   Cell Host & Microbe

Length-dependent recognition of double-stranded ribonucleic acids by retinoic acid–inducible gene-I and melanoma differentiation–associated gene 5

(2008) Hiroki Kato et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Delivery of Interferon-γ by an adenovirus vector blocks herpes simplex virus Type 1 reactivation in vitro and in vivo independent of RNase L and double-stranded RNA-dependent protein kinase pathways

(2008) Daniel J.J. Carr et al.   JOURNAL OF NEUROIMMUNOLOGY

Cellular FLIP can substitute for the herpes simplex virus type 1 latency-associated transcript gene to support a wild-type virus reactivation phenotype in mice

(2008) Ling Jin et al.   JOURNAL OF NEUROVIROLOGY

Reevaluating the CD8 T-Cell Response to Herpes Simplex Virus Type 1: Involvement of CD8 T Cells Reactive to Subdominant Epitopes

(2008) B. S. Sheridan et al.   JOURNAL OF VIROLOGY

Importance of NKT Cells in Resistance to Herpes Simplex Virus, Fate of Virus-Infected Neurons, and Level of Latency in Mice

(2008) B. Grubor-Bauk et al.   JOURNAL OF VIROLOGY

Chromatin control of herpes simplex virus lytic and latent infection

(2008) David M. Knipe et al.   NATURE REVIEWS MICROBIOLOGY

Noncytotoxic Lytic Granule-Mediated CD8+ T Cell Inhibition of HSV-1 Reactivation from Neuronal Latency

(2008) J. E. Knickelbein et al.   SCIENCE