The Fab portion of immunoglobulin G contributes to its binding to Fcγ receptor III

Recognition of Human IgG1 by Fcγ Receptors: Structural Insights from Hydrogen–Deuterium Exchange and Fast Photochemical Oxidation of Proteins Coupled with Mass Spectrometry

(2019) Liuqing Shi et al.   BIOCHEMISTRY

SWISS-MODEL: homology modelling of protein structures and complexes

(2018) Andrew Waterhouse et al.   NUCLEIC ACIDS RESEARCH

A single amino acid distorts the Fc γ receptor IIIb/CD16b structure upon binding immunoglobulin G1 and reduces affinity relative to CD16a

(2018) Jacob T. Roberts et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

IgG cooperativity – Is there allostery? Implications for antibody functions and therapeutic antibody development

(2017) Danlin Yang et al.   mAbs

Conformational effects of N-glycan core fucosylation of immunoglobulin G Fc region on its interaction with Fcγ receptor IIIa

(2017) Yoshitake Sakae et al.   Scientific Reports

Small-molecule inhibition of PTPRZ reduces tumor growth in a rat model of glioblastoma

(2016) Akihiro Fujikawa et al.   Scientific Reports

Structural analysis of Fc/FcγR complexes: a blueprint for antibody design

(2015) Jose M. M. Caaveiro et al.   IMMUNOLOGICAL REVIEWS

Structural Basis for Dimer Formation of Human Condensin Structural Maintenance of Chromosome Proteins and Its Implications for Single-stranded DNA Recognition

(2015) Susumu Uchiyama et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Rapid evaluation of N-glycosylation status of antibodies with chemiluminescent lectin-binding assay

(2015) Masayoshi Onitsuka et al.   JOURNAL OF BIOSCIENCE AND BIOENGINEERING

Importance of the Side Chain at Position 296 of Antibody Fc in Interactions with FcγRIIIa and Other Fcγ Receptors

(2015) Yuya Isoda et al.   PLoS One

Novel asymmetrically engineered antibody Fc variant with superior FcγR binding affinity and specificity compared with afucosylated Fc variant

(2013) Futa Mimoto et al.   mAbs

Properties of mouse and human IgG receptors and their contribution to disease models

(2012) P. Bruhns   BLOOD

The interactions of therapeutic antibodies with Fc receptors

(2012) Marcello Albanesi et al.   IMMUNOLOGY LETTERS

Guide to video recording of structure dynamics and dynamic processes of proteins by high-speed atomic force microscopy

(2012) Takayuki Uchihashi et al.   Nature Protocols

Structural basis for improved efficacy of therapeutic antibodies on defucosylation of their Fc glycans

(2011) Tsunehiro Mizushima et al.   GENES TO CELLS

Unique carbohydrate-carbohydrate interactions are required for high affinity binding between Fc RIII and antibodies lacking core fucose

(2011) C. Ferrara et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The Utility of Hydrogen/Deuterium Exchange Mass Spectrometry in Biopharmaceutical Comparability Studies

(2010) Damian Houde et al.   JOURNAL OF PHARMACEUTICAL SCIENCES

Production of therapeutic antibodies with controlled fucosylation

(2010) Naoko Yamane-Ohnuki et al.   mAbs

Post-translational Modifications Differentially Affect IgG1 Conformation and Receptor Binding

(2010) Damian Houde et al.   MOLECULAR & CELLULAR PROTEOMICS

Specificity and affinity of human Fc  receptors and their polymorphic variants for human IgG subclasses

(2008) P. Bruhns et al.   BLOOD

The N-linked oligosaccharide at Fc RIIIa Asn-45: an inhibitory element for high Fc RIIIa binding affinity to IgG glycoforms lacking core fucosylation

(2008) M. Shibata-Koyama et al.   GLYCOBIOLOGY

Optimization of antibody binding to Fc RIIa enhances macrophage phagocytosis of tumor cells

(2008) J. O. Richards et al.   MOLECULAR CANCER THERAPEUTICS