Native MS and ECD Characterization of a Fab–Antigen Complex May Facilitate Crystallization for X-ray Diffraction
Published 2016 View Full Article
- Home
- Publications
- Publication Search
- Publication Details
Title
Native MS and ECD Characterization of a Fab–Antigen Complex May Facilitate Crystallization for X-ray Diffraction
Authors
Keywords
Fourier transform ICR mass spectrometry, Native MS, Electron capture dissociation (ECD), X-raycrystallography, High-order structure (HOS), Fab-Antigen Complex, VEGF
Journal
JOURNAL OF THE AMERICAN SOCIETY FOR MASS SPECTROMETRY
Volume 27, Issue 7, Pages 1139-1142
Publisher
Springer Nature
Online
2016-04-22
DOI
10.1007/s13361-016-1398-9
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- Mapping of Fab-1:VEGF Interface Using Carboxyl Group Footprinting Mass Spectrometry
- (2015) Aaron T. Wecksler et al. JOURNAL OF THE AMERICAN SOCIETY FOR MASS SPECTROMETRY
- Characterizing monoclonal antibody structure by carboxyl group footprinting
- (2015) Parminder Kaur et al. mAbs
- Electron transfer dissociation provides higher-order structural information of native and partially unfolded protein complexes
- (2015) Frederik Lermyte et al. PROTEOMICS
- Mass Spectrometry Quantifies Protein Interactions-From Molecular Chaperones to Membrane Porins
- (2014) Jonathan T. S. Hopper et al. ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
- Analytical Approaches for Size and Mass Analysis of Large Protein Assemblies
- (2014) Joost Snijder et al. Annual Review of Analytical Chemistry
- Revealing Ligand Binding Sites and Quantifying Subunit Variants of Noncovalent Protein Complexes in a Single Native Top-Down FTICR MS Experiment
- (2014) Huilin Li et al. JOURNAL OF THE AMERICAN SOCIETY FOR MASS SPECTROMETRY
- ETD Allows for Native Surface Mapping of a 150 kDa Noncovalent Complex on a Commercial Q-TWIMS-TOF Instrument
- (2014) Frederik Lermyte et al. JOURNAL OF THE AMERICAN SOCIETY FOR MASS SPECTROMETRY
- An Improved Fast Photochemical Oxidation of Proteins (FPOP) Platform for Protein Therapeutics
- (2014) Ying Zhang et al. JOURNAL OF THE AMERICAN SOCIETY FOR MASS SPECTROMETRY
- Characterizing monoclonal antibody structure by carbodiimide/GEE footprinting
- (2014) Parminder Kaur et al. mAbs
- Native Top-Down Electrospray Ionization-Mass Spectrometry of 158 kDa Protein Complex by High-Resolution Fourier Transform Ion Cyclotron Resonance Mass Spectrometry
- (2013) Huilin Li et al. ANALYTICAL CHEMISTRY
- Mass spectrometry for the biophysical characterization of therapeutic monoclonal antibodies
- (2013) Hao Zhang et al. FEBS LETTERS
- Complementary MS Methods Assist Conformational Characterization of Antibodies with Altered S–S Bonding Networks
- (2013) Lisa M. Jones et al. JOURNAL OF THE AMERICAN SOCIETY FOR MASS SPECTROMETRY
- Structural analysis of a therapeutic monoclonal antibody dimer by hydroxyl radical footprinting
- (2013) Galahad Deperalta et al. mAbs
- Pulsed hydrogen–deuterium exchange mass spectrometry probes conformational changes in amyloid beta (Aβ) peptide aggregation
- (2013) Ying Zhang et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Characterization of Therapeutic Antibodies and Related Products
- (2012) Alain Beck et al. ANALYTICAL CHEMISTRY
- Biosimilar, Biobetter, and Next Generation Antibody Characterization by Mass Spectrometry
- (2012) Alain Beck et al. ANALYTICAL CHEMISTRY
- Unit Mass Baseline Resolution for an Intact 148 kDa Therapeutic Monoclonal Antibody by Fourier Transform Ion Cyclotron Resonance Mass Spectrometry
- (2011) Santosh G. Valeja et al. ANALYTICAL CHEMISTRY
- Native Electrospray and Electron-Capture Dissociation FTICR Mass Spectrometry for Top-Down Studies of Protein Assemblies
- (2011) Hao Zhang et al. ANALYTICAL CHEMISTRY
- Native Electrospray and Electron-Capture Dissociation in FTICR Mass Spectrometry Provide Top-Down Sequencing of a Protein Component in an Intact Protein Assembly
- (2010) Hao Zhang et al. JOURNAL OF THE AMERICAN SOCIETY FOR MASS SPECTROMETRY
- In Situ Proteolysis to Generate Crystals for Structure Determination: An Update
- (2009) Amy Wernimont et al. PLoS One
- Characterization of IgG1 Immunoglobulins and Peptide−Fc Fusion Proteins by Limited Proteolysis in Conjunction with LC−MS
- (2008) Gerd R. Kleemann et al. ANALYTICAL CHEMISTRY
- Mass spectrometry for structural characterization of therapeutic antibodies
- (2008) Zhongqi Zhang et al. MASS SPECTROMETRY REVIEWS
Discover Peeref hubs
Discuss science. Find collaborators. Network.
Join a conversationAsk a Question. Answer a Question.
Quickly pose questions to the entire community. Debate answers and get clarity on the most important issues facing researchers.
Get Started