Crosstalk between endoplasmic reticulum stress and oxidative stress: Focus on protein disulfide isomerase and endoplasmic reticulum oxidase 1

Lysyl Oxidase Like 1: Biological roles and regulation

(2020) Alison G Greene et al.   EXPERIMENTAL EYE RESEARCH

The Role of Hydrogen Peroxide and Peroxiredoxins throughout the Cell Cycle

(2020) Sukyeong Heo et al.   Antioxidants

Characterization of Aminobenzylphenols as Protein Disulfide Isomerase Inhibitors in Glioblastoma Cell Lines

(2020) Andrea Shergalis et al.   JOURNAL OF MEDICINAL CHEMISTRY

Redox Activation of Nox1 (NADPH Oxidase 1) Involves an Intermolecular Disulfide Bond Between Protein Disulfide Isomerase and p47 phox in Vascular Smooth Muscle Cells

(2019) Marcela Gimenez et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

The C/EBP Homologous Protein (CHOP) Transcription Factor Functions in Endoplasmic Reticulum Stress-Induced Apoptosis and Microbial Infection

(2019) Hai Hu et al.   Frontiers in Immunology

Targeting the functional interplay between endoplasmic reticulum oxidoreductin-1α and protein disulfide isomerase suppresses the progression of cervical cancer

(2019) Yini Zhang et al.   EBioMedicine

Crosstalk Between Oxidative Stress and Endoplasmic Reticulum (ER) Stress in Endothelial Dysfunction and Aberrant Angiogenesis Associated With Diabetes: A Focus on the Protective Roles of Heme Oxygenase (HO)-1

(2019) Hatem Maamoun et al.   Frontiers in Physiology

Linking the Endoplasmic Reticulum to Parkinson’s Disease and Alpha-Synucleinopathy

(2019) Emanuela Colla   Frontiers in Neuroscience

Activation of PERK-eIF2α-ATF4 pathway contributes to diabetic hepatotoxicity: Attenuation of ER stress by Morin

(2019) Vivek Kumar Pandey et al.   CELLULAR SIGNALLING

Communications Between the Endoplasmic Reticulum and Other Organelles During Abiotic Stress Response in Plants

(2019) Linchuan Liu et al.   Frontiers in Plant Science

Editorial: Producing, Sensing and Responding to Cellular Stress in Immunity

(2019) Heitor A. Paula-Neto et al.   Frontiers in Immunology

Cellular Stress-Modulating Drugs Can Potentially Be Identified by in Silico Screening with Connectivity Map (CMap)

(2019) Yurong Gao et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

IP3 receptor isoforms differently regulate ER-mitochondrial contacts and local calcium transfer

(2019) Adam Bartok et al.   Nature Communications

Discovery and Mechanistic Elucidation of a Class of Protein Disulfide Isomerase Inhibitors for the Treatment of Glioblastoma

(2018) Anahita Kyani et al.   ChemMedChem

Quercetin improves endothelial function in diabetic rats through inhibition of endoplasmic reticulum stress-mediated oxidative stress

(2018) Natarajan Suganya et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Small molecule modulator of protein disulfide isomerase attenuates mutant huntingtin toxicity and inhibits endoplasmic reticulum stress in a mouse model of Huntington’s disease

(2018) Xiao Zhou et al.   HUMAN MOLECULAR GENETICS

Endoplasmic reticulum stress responses in mouse models of Alzheimer's disease: Overexpression paradigmversusknockin paradigm

(2018) Shoko Hashimoto et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Establishment of pancreatic microenvironment model of ER stress: Quercetin attenuates β-cell apoptosis by invoking nitric oxide-cGMP signaling in endothelial cells

(2018) Natarajan Suganya et al.   JOURNAL OF NUTRITIONAL BIOCHEMISTRY

The Endoplasmic Reticulum Stress Response in Neuroprogressive Diseases: Emerging Pathophysiological Role and Translational Implications

(2018) Gerwyn Morris et al.   MOLECULAR NEUROBIOLOGY

Effects of proinsulin misfolding on β-cell dynamics, differentiation and function in diabetes

(2018) Yael Riahi et al.   DIABETES OBESITY & METABOLISM

Homocysteine causes vascular endothelial dysfunction by disrupting endoplasmic reticulum redox homeostasis

(2018) Xun Wu et al.   Redox Biology

Single-Cell Sequencing of iPSC-Dopamine Neurons Reconstructs Disease Progression and Identifies HDAC4 as a Regulator of Parkinson Cell Phenotypes

(2018) Charmaine Lang et al.   Cell Stem Cell

Hypoxia evokes increased PDI and PDIA6 expression in the infarcted myocardium of ex-germ-free and conventionally raised mice

(2018) Klytaimnistra Kiouptsi et al.   Biology Open

Endoplasmic Reticulum Unfolded Protein Response, Aging and Exercise: An Update

(2018) Brisamar Estébanez et al.   Frontiers in Physiology

Morin activates the Nrf2-ARE pathway and reduces oxidative stress-induced DNA damage in pancreatic beta cells

(2017) Pachamuthu Vanitha et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Cataracts

(2017) Yu-Chi Liu et al.   LANCET

ER stress and distinct outputs of the IRE1α RNase control proliferation and senescence in response to oncogenic Ras

(2017) Nicholas Blazanin et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Protein disulfide isomerase-mediated apoptosis and proliferation of vascular smooth muscle cells induced by mechanical stress and advanced glycosylation end products result in diabetic mouse vein graft atherosclerosis

(2017) Suning Ping et al.   Cell Death & Disease

Cancer-associated oxidoreductase ERO1-α promotes immune escape through up-regulation of PD-L1 in human breast cancer

(2017) Tsutomu Tanaka et al.   Oncotarget

GRP78 at the Centre of the Stage in Cancer and Neuroprotection

(2017) Caty Casas   Frontiers in Neuroscience

Transcription Factor C/EBP Homologous Protein in Health and Diseases

(2017) Yuan Yang et al.   Frontiers in Immunology

HPW-RX40 prevents human platelet activation by attenuating cell surface protein disulfide isomerases

(2017) Po-Hsiung Kung et al.   Redox Biology

Inhibition of Excessive Oxidative Protein Folding Is Protective in MPP+ Toxicity-Induced Parkinson's Disease Models

(2016) Šárka Lehtonen et al.   ANTIOXIDANTS & REDOX SIGNALING

Mitochondrial Reactive Oxygen Species Mediate Lysophosphatidylcholine-Induced Endothelial Cell ActivationHighlights

(2016) Xinyuan Li et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Cancer-associated oxidoreductase ERO1-α drives the production of VEGF via oxidative protein folding and regulating the mRNA level

(2016) Tsutomu Tanaka et al.   BRITISH JOURNAL OF CANCER

Novel Protein Disulfide Isomerase Inhibitor with Anticancer Activity in Multiple Myeloma

(2016) S. Vatolin et al.   CANCER RESEARCH

The Role of the PERK/eIF2α/ATF4/CHOP Signaling Pathway in Tumor Progression During Endoplasmic Reticulum Stress

(2016) W. Rozpedek et al.   CURRENT MOLECULAR MEDICINE

Endoplasmic Reticulum Stress and Associated ROS

(2016) Hafiz Zeeshan et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Endoplasmic Reticulum Stress Is a Danger Signal Promoting Innate Inflammatory Responses in Bronchial Epithelial Cells

(2016) Vedrana Mijošek et al.   Journal of Innate Immunity

Endoplasmic reticulum stress-induced neuronal inflammatory response and apoptosis likely plays a key role in the development of diabetic encephalopathy

(2016) Zhouguang Wang et al.   Oncotarget

Interactions between mitochondrial reactive oxygen species and cellular glucose metabolism

(2015) Dania C. Liemburg-Apers et al.   ARCHIVES OF TOXICOLOGY

C/EBP homologous protein (CHOP) contributes to hepatocyte death via the promotion of ERO1α signalling in acute liver failure

(2015) Jianhua Rao et al.   BIOCHEMICAL JOURNAL

Cell death induced by endoplasmic reticulum stress

(2015) Raffaella Iurlaro et al.   FEBS Journal

Quercetin-3-rutinoside Inhibits Protein Disulfide Isomerase by Binding to Its b′x Domain

(2015) Lin Lin et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Cancer-Associated Oxidase ERO1-α Regulates the Expression of MHC Class I Molecule via Oxidative Folding

(2015) Kazuharu Kukita et al.   JOURNAL OF IMMUNOLOGY

Small molecule-induced oxidation of protein disulfide isomerase is neuroprotective

(2015) Anna Kaplan et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

New insights into the roles of CHOP-induced apoptosis in ER stress

(2014) Yiming Li et al.   ACTA BIOCHIMICA ET BIOPHYSICA SINICA

Endoplasmic Reticulum Stress and Oxidative Stress in Cell Fate Decision and Human Disease

(2014) Stewart Siyan Cao et al.   ANTIOXIDANTS & REDOX SIGNALING

Adenanthin targets proteins involved in the regulation of disulphide bonds

(2014) Angelika Muchowicz et al.   BIOCHEMICAL PHARMACOLOGY

Selenite cataracts: Activation of endoplasmic reticulum stress and loss of Nrf2/Keap1-dependent stress protection

(2014) Periyasamy Palsamy et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

Valproic acid suppresses Nrf2/Keap1 dependent antioxidant protection through induction of endoplasmic reticulum stress and Keap1 promoter DNA demethylation in human lens epithelial cells

(2014) Periyasamy Palsamy et al.   EXPERIMENTAL EYE RESEARCH

Inhibition of the Functional Interplay between Endoplasmic Reticulum (ER) Oxidoreduclin-1α (Ero1α) and Protein-disulfide Isomerase (PDI) by the Endocrine Disruptor Bisphenol A

(2014) Masaki Okumura et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Cutting Edge: Endoplasmic Reticulum Stress Licenses Macrophages To Produce Mature IL-1  in Response to TLR4 Stimulation through a Caspase-8- and TRIF-Dependent Pathway

(2014) K. Shenderov et al.   JOURNAL OF IMMUNOLOGY

Amyloid-Beta Disrupts Calcium and Redox Homeostasis in Brain Endothelial Cells

(2014) Ana Catarina R. G. Fonseca et al.   MOLECULAR NEUROBIOLOGY

A Molecular Web: Endoplasmic Reticulum Stress, Inflammation, and Oxidative Stress

(2014) Namrata Chaudhari et al.   Frontiers in Cellular Neuroscience

Toll-like receptor-mediated IRE1α activation as a therapeutic target for inflammatory arthritis

(2013) Quan Qiu et al.   EMBO JOURNAL

Circulating Levels of IL-1B+IL-6 Cause ER Stress and Dysfunction in Islets From Prediabetic Male Mice

(2013) Christina M. O'Neill et al.   ENDOCRINOLOGY

The Large Hsp70 Grp170 Binds to Unfolded Protein Substratesin Vivowith a Regulation Distinct from Conventional Hsp70s

(2013) Julia Behnke et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Ero1-α and PDIs constitute a hierarchical electron transfer network of endoplasmic reticulum oxidoreductases

(2013) Kazutaka Araki et al.   JOURNAL OF CELL BIOLOGY

Interactions between sarco-endoplasmic reticulum and mitochondria in cardiac and skeletal muscle - pivotal roles in Ca2+ and reactive oxygen species signaling

(2013) V. Eisner et al.   JOURNAL OF CELL SCIENCE

Functional and morphological impact of ER stress on mitochondria

(2013) Kayleen Vannuvel et al.   JOURNAL OF CELLULAR PHYSIOLOGY

1,3,5-Triazine as a Modular Scaffold for Covalent Inhibitors with Streamlined Target Identification

(2013) Ranjan Banerjee et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

The role of the unfolded protein response in diabetes mellitus

(2013) Takao Iwawaki et al.   Seminars in Immunopathology

Endoplasmic Reticulum Stress Sensing in the Unfolded Protein Response

(2013) B. M. Gardner et al.   Cold Spring Harbor Perspectives in Biology

Age-related cataracts: Homocysteine coupled endoplasmic reticulum stress and suppression of Nrf2-dependent antioxidant protection

(2012) Rajan Elanchezhian et al.   CHEMICO-BIOLOGICAL INTERACTIONS

Protein disulfide isomerase inhibitors constitute a new class of antithrombotic agents

(2012) Reema Jasuja et al.   JOURNAL OF CLINICAL INVESTIGATION

Discovery of an orally active small-molecule irreversible inhibitor of protein disulfide isomerase for ovarian cancer treatment

(2012) S. Xu et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Ero1α Regulates Ca2+ Fluxes at the Endoplasmic Reticulum–Mitochondria Interface (MAM)

(2011) Tiziana Anelli et al.   ANTIOXIDANTS & REDOX SIGNALING

Global estimates of visual impairment: 2010

(2011) Donatella Pascolini et al.   BRITISH JOURNAL OF OPHTHALMOLOGY

VDAC1 selectively transfers apoptotic Ca2+ signals to mitochondria

(2011) D De Stefani et al.   CELL DEATH AND DIFFERENTIATION

The sarcoplasmic reticulum luminal thiol oxidase ERO1 regulates cardiomyocyte excitation-coupled calcium release and response to hemodynamic load

(2011) King-Tung Chin et al.   FASEB JOURNAL

Protein disulfide isomerase knockdown-induced cell death is cell-line-dependent and involves apoptosis in MCF-7 cells

(2011) Tomoyo Hashida et al.   JOURNAL OF TOXICOLOGICAL SCIENCES

Genes of the Unfolded Protein Response Pathway Harbor Risk Alleles for Primary Open Angle Glaucoma

(2011) Mary Anna Carbone et al.   PLoS One

Discovery of a Small Molecule PDI Inhibitor That Inhibits Reduction of HIV-1 Envelope Glycoprotein gp120

(2010) Maola M. G. Khan et al.   ACS Chemical Biology

Human pancreas-specific protein disulfide-isomerase (PDIp) can function as a chaperone independently of its enzymatic activity by forming stable complexes with denatured substrate proteins

(2010) Xin-Miao Fu et al.   BIOCHEMICAL JOURNAL

Calcium uptake mechanisms of mitochondria

(2010) Jaime Santo-Domingo et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOENERGETICS

Targeting ER stress induced apoptosis and inflammation in cancer

(2010) Tom Verfaillie et al.   CANCER LETTERS

Sustained production of spliced X-box binding protein 1 (XBP1) induces pancreatic beta cell dysfunction and apoptosis

(2010) F. Allagnat et al.   DIABETOLOGIA

A structural overview of the PDI family of proteins

(2010) Guennadi Kozlov et al.   FEBS Journal

A Small Molecule Inhibitor of Endoplasmic Reticulum Oxidation 1 (ERO1) with Selectively Reversible Thiol Reactivity

(2010) Jaime D. Blais et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

ERO1-β, a pancreas-specific disulfide oxidase, promotes insulin biogenesis and glucose homeostasis

(2010) Ester Zito et al.   JOURNAL OF CELL BIOLOGY

Inhibitors of protein disulfide isomerase suppress apoptosis induced by misfolded proteins

(2010) Benjamin G Hoffstrom et al.   Nature Chemical Biology

TLR activation of the transcription factor XBP1 regulates innate immune responses in macrophages

(2010) Fabio Martinon et al.   NATURE IMMUNOLOGY

Insights into MHC Class I Peptide Loading from the Structure of the Tapasin-ERp57 Thiol Oxidoreductase Heterodimer

(2009) Gang Dong et al.   IMMUNITY

Role of ERO1-α–mediated stimulation of inositol 1,4,5-triphosphate receptor activity in endoplasmic reticulum stress–induced apoptosis

(2009) Gang Li et al.   JOURNAL OF CELL BIOLOGY

Significance of Interactions of Low Molecular Weight Crystallin Fragments in Lens Aging and Cataract Formation

(2008) Puttur Santhoshkumar et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

GRP78, but Not Protein-disulfide Isomerase, Partially Reverses Hyperglycemia-induced Inhibition of Insulin Synthesis and Secretion in Pancreatic β-Cells

(2008) Liling Zhang et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

From endoplasmic-reticulum stress to the inflammatory response

(2008) Kezhong Zhang et al.   NATURE

Ero1 and redox homeostasis in the endoplasmic reticulum

(2007) Carolyn S. Sevier et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH