The Large Hsp70 Grp170 Binds to Unfolded Protein Substratesin Vivowith a Regulation Distinct from Conventional Hsp70s

Proteomic data from human cell cultures refine mechanisms of chaperone-mediated protein homeostasis

(2013) Andrija Finka et al.   CELL STRESS & CHAPERONES

The Lhs1/GRP170 Chaperones Facilitate the Endoplasmic Reticulum-associated Degradation of the Epithelial Sodium Channel

(2013) Teresa M. Buck et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Quality Control of Integral Membrane Proteins by Assembly-Dependent Membrane Integration

(2013) Matthias J. Feige et al.   MOLECULAR CELL

C-terminal Mutations Destabilize SIL1/BAP and Can Cause Marinesco-Sjögren Syndrome

(2012) Jennifer Howes et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Flagging and docking: dual roles for N-glycans in protein quality control and cellular proteostasis

(2012) Daniel N. Hebert et al.   TRENDS IN BIOCHEMICAL SCIENCES

Protein Folding and Modification in the Mammalian Endoplasmic Reticulum

(2011) Ineke Braakman et al.   Annual Review of Biochemistry

Unique Peptide Substrate Binding Properties of 110-kDa Heat-shock Protein (Hsp110) Determine Its Distinct Chaperone Activity

(2011) Xinping Xu et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Molecular chaperones in protein folding and proteostasis

(2011) F. Ulrich Hartl et al.   NATURE

The Endoplasmic Reticulum Grp170 Acts as a Nucleotide Exchange Factor of Hsp70 via a Mechanism Similar to That of the Cytosolic Hsp110

(2010) Claes Andréasson et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Interaction of the Hsp110 Molecular Chaperones from S. cerevisiae with Substrate Protein

(2010) Sigrun Polier et al.   JOURNAL OF MOLECULAR BIOLOGY

The HSP70 chaperone machinery: J proteins as drivers of functional specificity

(2010) Harm H. Kampinga et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Nucleotide Binding by Lhs1p Is Essential for Its Nucleotide Exchange Activity and for Functionin Vivo

(2009) Jeanine de Keyzer et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

An Unfolded CH1 Domain Controls the Assembly and Secretion of IgG Antibodies

(2009) Matthias J. Feige et al.   MOLECULAR CELL

Life and death of a BiP substrate

(2009) Joel H. Otero et al.   SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY

Structural Basis for the Cooperation of Hsp70 and Hsp110 Chaperones in Protein Folding

(2008) Sigrun Polier et al.   CELL

The yeast Hsp110, Sse1p, exhibits high-affinity peptide binding

(2008) Jennifer L. Goeckeler et al.   FEBS LETTERS

Structure of the Hsp110:Hsc70 Nucleotide Exchange Machine

(2008) Jonathan P. Schuermann et al.   MOLECULAR CELL