- Home
- Publications
- Publication Search
- Publication Details
Title
GRP78 at the Centre of the Stage in Cancer and Neuroprotection
Authors
Keywords
-
Journal
Frontiers in Neuroscience
Volume 11, Issue -, Pages -
Publisher
Frontiers Media SA
Online
2017-04-05
DOI
10.3389/fnins.2017.00177
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- PPARβ/δ activation protects against corticosterone-induced ER stress in astrocytes by inhibiting the CpG hypermethylation of microRNA-181a
- (2017) Juan Ji et al. NEUROPHARMACOLOGY
- The ER proteostasis network in ALS: Determining the differential motoneuron vulnerability
- (2017) Pablo Rozas et al. NEUROSCIENCE LETTERS
- Modulation of SQSTM1/p62 activity by N-terminal arginylation of the endoplasmic reticulum chaperone HSPA5/GRP78/BiP
- (2016) Hyunjoo Cha-Molstad et al. Autophagy
- Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)
- (2016) Daniel J Klionsky et al. Autophagy
- Endoplasmic Reticulum Stress Protein GRP78 Modulates Lipid Metabolism to Control Drug Sensitivity and Antitumor Immunity in Breast Cancer
- (2016) Katherine L. Cook et al. CANCER RESEARCH
- Mitochondria-associated ER membranes and Alzheimer disease
- (2016) Estela Area-Gomez et al. CURRENT OPINION IN GENETICS & DEVELOPMENT
- ER strikes again: Proteostasis Dysfunction In ALS
- (2016) Niran Maharjan et al. EMBO JOURNAL
- Caloric restriction and the precision-control of autophagy: A strategy for delaying neurodegenerative disease progression
- (2016) C. Ntsapi et al. EXPERIMENTAL GERONTOLOGY
- Membrane Protein Quantity Control at the Endoplasmic Reticulum
- (2016) Ignat Printsev et al. JOURNAL OF MEMBRANE BIOLOGY
- Protein misfolding in the endoplasmic reticulum as a conduit to human disease
- (2016) Miao Wang et al. NATURE
- GRP78 is required for cell proliferation and protection from apoptosis in chicken embryo fibroblast cells
- (2016) M. Jeon et al. POULTRY SCIENCE
- GRP78 is implicated in the modulation of tumor aerobic glycolysis by promoting autophagic degradation of IKKβ
- (2015) Zongwei Li et al. CELLULAR SIGNALLING
- Characterization and Mechanism of Stress-induced Translocation of 78-Kilodalton Glucose-regulated Protein (GRP78) to the Cell Surface
- (2015) Yuan-Li Tsai et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Micro-RNA-30a regulates ischemia-induced cell death by targeting heat shock protein HSPA5 in primary cultured cortical neurons and mouse brain after stroke
- (2015) Peng Wang et al. JOURNAL OF NEUROSCIENCE RESEARCH
- GRP78 rescues the ABCG5 ABCG8 sterol transporter in db/db mice
- (2015) Yuhuan Wang et al. METABOLISM-CLINICAL AND EXPERIMENTAL
- SIL1 Rescued Bip Elevation-Related Tau Hyperphosphorylation in ER Stress
- (2015) Zan-Chao Liu et al. MOLECULAR NEUROBIOLOGY
- Amino-terminal arginylation targets endoplasmic reticulum chaperone BiP for autophagy through p62 binding
- (2015) Hyunjoo Cha-Molstad et al. NATURE CELL BIOLOGY
- The loss of glucose-regulated protein 78 (GRP78) during normal aging or from siRNA knockdown augments human alpha-synuclein (α-syn) toxicity to rat nigral neurons
- (2015) Maxim Salganik et al. NEUROBIOLOGY OF AGING
- Unfolding the Promise of Translational Targeting in Neurodegenerative Disease
- (2015) Thomas M. Drake NEUROMOLECULAR MEDICINE
- GRP78 confers the resistance to 5-FU by activating the c-Src/LSF/TS Axis in hepatocellular carcinoma
- (2015) Yan-jiao Gu et al. Oncotarget
- Molecular chaperone GRP78 enhances aggresome delivery to autophagosomes to promote drug resistance in multiple myeloma
- (2015) Mohamed A.Y. Abdel Malek et al. Oncotarget
- The roles of lipid and glucose metabolism in modulation of β-amyloid, tau, and neurodegeneration in the pathogenesis of Alzheimer disease
- (2015) Naoyuki Sato et al. Frontiers in Aging Neuroscience
- Endoplasmic reticulum chaperone GRP78 is involved in autophagy activation induced by ischemic preconditioning in neural cells
- (2015) Xiang-Yang Zhang et al. Molecular Brain
- Immunoglobulin heavy-chain-binding protein (BiP): a stress protein that has the potential to be a novel therapy for rheumatoid arthritis
- (2014) Gabriel S. Panayi et al. BIOCHEMICAL SOCIETY TRANSACTIONS
- Mechanism of endoplasmic reticulum stress-induced vascular endothelial dysfunction
- (2014) Maria Galán et al. BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH
- Raf/MEK/ERK can regulate cellular levels of LC3B and SQSTM1/p62 at expression levels
- (2014) Jin-Hwan Kim et al. EXPERIMENTAL CELL RESEARCH
- GRP78 is a novel receptor initiating a vascular barrier protective response to oxidized phospholipids
- (2014) Anna A. Birukova et al. MOLECULAR BIOLOGY OF THE CELL
- Late-Onset of Spinal Neurodegeneration in Knock-In Mice Expressing a Mutant BiP
- (2014) Hisayo Jin et al. PLoS One
- MicroRNA-376a Regulates 78-Kilodalton Glucose-Regulated Protein Expression in Rat Granulosa Cells
- (2014) Masayuki Iwamune et al. PLoS One
- Protective Role of DNJ-27/ERdj5 in Caenorhabditis elegans Models of Human Neurodegenerative Diseases
- (2013) Fernando Muñoz-Lobato et al. ANTIOXIDANTS & REDOX SIGNALING
- The role of phospholipids in the biological activity and structure of the endoplasmic reticulum
- (2013) Thomas A. Lagace et al. BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH
- Intracellular Accumulation of Toxic Turn Amyloid-β is Associated with Endoplasmic Reticulum Stress in Alzheimer’s Disease
- (2013) Naoko Soejima et al. Current Alzheimer Research
- Up-to-date membrane biogenesis in the autophagosome formation
- (2013) Maho Hamasaki et al. CURRENT OPINION IN CELL BIOLOGY
- Cell-surface GRP78 facilitates colorectal cancer cell migration and invasion
- (2013) Zongwei Li et al. INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY
- Downregulation of miR-181b in mouse brain following ischemic stroke induces neuroprotection against ischemic injury through targeting heat shock protein A5 and ubiquitin carboxyl-terminal hydrolase isozyme L1
- (2013) Zhifeng Peng et al. JOURNAL OF NEUROSCIENCE RESEARCH
- ULK1 induces autophagy by phosphorylating Beclin-1 and activating VPS34 lipid kinase
- (2013) Ryan C. Russell et al. NATURE CELL BIOLOGY
- Endoplasmic Reticulum Stress Sensing in the Unfolded Protein Response
- (2013) B. M. Gardner et al. Cold Spring Harbor Perspectives in Biology
- Heat shock 70 kDa protein 5/glucose-regulated protein 78 “AMP”ing up autophagy
- (2012) Katherine L. Cook et al. Autophagy
- Glucose-Regulated Protein 78 Controls Cross-talk between Apoptosis and Autophagy to Determine Antiestrogen Responsiveness
- (2012) K. L. Cook et al. CANCER RESEARCH
- Vaspin Is an Adipokine Ameliorating ER Stress in Obesity as a Ligand for Cell-Surface GRP78/MTJ-1 Complex
- (2012) A. Nakatsuka et al. DIABETES
- Identification of a potential tumor differentiation factor receptor candidate in prostate cancer cells
- (2012) Izabela Sokolowska et al. FEBS Journal
- Cripto/GRP78 modulation of the TGF-β pathway in development and oncogenesis
- (2012) Peter C. Gray et al. FEBS LETTERS
- Endoplasmic Reticulum Stress Is Important for the Manifestations of -Synucleinopathy In Vivo
- (2012) E. Colla et al. JOURNAL OF NEUROSCIENCE
- Glucose Regulated Protein 78 Diminishes α-Synuclein Neurotoxicity in a Rat Model of Parkinson Disease
- (2012) Marina S Gorbatyuk et al. MOLECULAR THERAPY
- Sigma-1R Agonist Improves Motor Function and Motoneuron Survival in ALS Mice
- (2012) Renzo Mancuso et al. Neurotherapeutics
- The endoplasmic reticulum stress response in aging and age-related diseases
- (2012) Marishka K. Brown et al. Frontiers in Physiology
- Beyond the endoplasmic reticulum: atypical GRP78 in cell viability, signalling and therapeutic targeting
- (2011) Min Ni et al. BIOCHEMICAL JOURNAL
- Autophagy and BiP level decrease are early key events in retrograde degeneration of motoneurons
- (2011) C Penas et al. CELL DEATH AND DIFFERENTIATION
- Sigma Receptor Agonist 2-(4-Morpholinethyl)1 Phenylcyclohexanecarboxylate (Pre084) Increases GDNF and BiP Expression and Promotes Neuroprotection after Root Avulsion Injury
- (2011) Clara Penas et al. JOURNAL OF NEUROTRAUMA
- Linking lipids to Alzheimer's disease: cholesterol and beyond
- (2011) Gilbert Di Paolo et al. NATURE REVIEWS NEUROSCIENCE
- miR-181 regulates GRP78 and influences outcome from cerebral ischemia in vitro and in vivo
- (2011) Yi-Bing Ouyang et al. NEUROBIOLOGY OF DISEASE
- Calcium Ions Promote Formation of Amyloid β-Peptide (1–40) Oligomers Causally Implicated in Neuronal Toxicity of Alzheimer's Disease
- (2011) Anna Itkin et al. PLoS One
- Unfolded Proteins Are Ire1-Activating Ligands That Directly Induce the Unfolded Protein Response
- (2011) B. M. Gardner et al. SCIENCE
- Characterization of autophagosome formation site by a hierarchical analysis of mammalian Atg proteins
- (2010) Eisuke Itakura et al. Autophagy
- Ligation of cell surface GRP78 with antibody directed against the COOH-terminal domain of GRP78 suppresses Ras/MAPK and PI 3-kinase/AKT signaling while promoting caspase activation in human prostate cancer cells
- (2010) Uma K. Misra et al. CANCER BIOLOGY & THERAPY
- Bcl-2 proteins regulate ER membrane permeability to luminal proteins during ER stress-induced apoptosis
- (2010) X Wang et al. CELL DEATH AND DIFFERENTIATION
- The critical role of GRP78 in physiologic and pathologic stress
- (2010) Kyle T Pfaffenbach et al. CURRENT OPINION IN CELL BIOLOGY
- Induction of the unfolded protein response and cell death pathway in Alzheimer's disease, but not in aged Tg2576 mice
- (2010) Jin Hwan Lee et al. EXPERIMENTAL AND MOLECULAR MEDICINE
- Cell Surface Relocalization of the Endoplasmic Reticulum Chaperone and Unfolded Protein Response Regulator GRP78/BiP
- (2010) Yi Zhang et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Autophagy requires endoplasmic reticulum targeting of the PI3-kinase complex via Atg14L
- (2010) Kohichi Matsunaga et al. JOURNAL OF CELL BIOLOGY
- Induction of the unfolded protein response by α-synuclein in experimental models of Parkinson’s disease
- (2010) Arianna Bellucci et al. JOURNAL OF NEUROCHEMISTRY
- Evidence for Translational Regulation by the Herpes Simplex Virus Virion Host Shutoff Protein
- (2010) H. A. Saffran et al. JOURNAL OF VIROLOGY
- Human Cytomegalovirus Induces the Endoplasmic Reticulum Chaperone BiP through Increased Transcription and Activation of Translation by Using the BiP Internal Ribosome Entry Site
- (2010) N. J. Buchkovich et al. JOURNAL OF VIROLOGY
- Overexpressing GRP78 influences Ca2+ handling and function of mitochondria in astrocytes after ischemia-like stress
- (2010) Yi-Bing Ouyang et al. MITOCHONDRION
- Autophagy and the Integrated Stress Response
- (2010) Guido Kroemer et al. MOLECULAR CELL
- Wild-type and mutant SOD1 share an aberrant conformation and a common pathogenic pathway in ALS
- (2010) Daryl A Bosco et al. NATURE NEUROSCIENCE
- Transcriptional Analysis Implicates Endoplasmic Reticulum Stress in Bovine Spongiform Encephalopathy
- (2010) Yue Tang et al. PLoS One
- Protein quality control in the ER: The recognition of misfolded proteins
- (2010) Pekka Määttänen et al. SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY
- BiP Binding to the ER-Stress Sensor Ire1 Tunes the Homeostatic Behavior of the Unfolded Protein Response
- (2010) David Pincus et al. PLOS BIOLOGY
- Aging: Central role for autophagy and the lysosomal degradative system
- (2009) Yogendra S. Rajawat et al. AGEING RESEARCH REVIEWS
- Modulation of the unfolded protein response in prostate cancer cells by antibody-directed against the carboxyl-terminal domain of GRP78
- (2009) U. K. Misra et al. APOPTOSIS
- Essential role of the unfolded protein response regulator GRP78/BiP in protection from neuronal apoptosis
- (2009) M Wang et al. CELL DEATH AND DIFFERENTIATION
- Extracellular chaperones modulate the effects of Alzheimer’s patient cerebrospinal fluid on Aβ1-42 toxicity and uptake
- (2009) Justin J. Yerbury et al. CELL STRESS & CHAPERONES
- Grp78 Heterozygosity Promotes Adaptive Unfolded Protein Response and Attenuates Diet-Induced Obesity and Insulin Resistance
- (2009) R. Ye et al. DIABETES
- Glucose-regulated protein 78 (Grp78/BiP) is secreted by human oviduct epithelial cells and the recombinant protein modulates sperm–zona pellucida binding
- (2009) Clara I. Marín-Briggiler et al. FERTILITY AND STERILITY
- GRP78 expression inhibits insulin and ER stress–induced SREBP-1c activation and reduces hepatic steatosis in mice
- (2009) Hélène L. Kammoun et al. JOURNAL OF CLINICAL INVESTIGATION
- Cytoskeletal and Activity-Related Changes in Spinal Motoneurons after Root Avulsion
- (2009) Clara Penas et al. JOURNAL OF NEUROTRAUMA
- Ligation of cancer cell surface GRP78 with antibodies directed against its COOH-terminal domain up-regulates p53 activity and promotes apoptosis
- (2009) U. K. Misra et al. MOLECULAR CANCER THERAPEUTICS
- A subdomain of the endoplasmic reticulum forms a cradle for autophagosome formation
- (2009) Mitsuko Hayashi-Nishino et al. NATURE CELL BIOLOGY
- Selective sigma receptor agonist 2-(4-morpholinethyl)1-phenylcyclohexanecarboxylate (PRE084) promotes neuroprotection and neurite elongation through protein kinase C (PKC) signaling on motoneurons
- (2009) M.-S. Guzmán-Lenis et al. NEUROSCIENCE
- Blockade of Cripto binding to cell surface GRP78 inhibits oncogenic Cripto signaling via MAPK/PI3K and Smad2/3 pathways
- (2009) J A Kelber et al. ONCOGENE
- Regulation of PERK Signaling and Leukemic Cell Survival by a Novel Cytosolic Isoform of the UPR Regulator GRP78/BiP
- (2009) Min Ni et al. PLoS One
- Life and death of a BiP substrate
- (2009) Joel H. Otero et al. SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY
- The unfolded protein response regulator GRP78/BiP is required for endoplasmic reticulum integrity and stress-induced autophagy in mammalian cells
- (2008) J Li et al. CELL DEATH AND DIFFERENTIATION
- Regulated association of misfolded endoplasmic reticulum lumenal proteins with P58/DNAJc3
- (2008) Kseniya Petrova et al. EMBO JOURNAL
- Malondialdehyde, carbonyl proteins and albumin-disulphide as useful oxidative markers in mild cognitive impairment and Alzheimer's disease
- (2008) J. Greilberger et al. FREE RADICAL RESEARCH
- The Hepatitis B Virus Precore Protein Is Retrotransported from Endoplasmic Reticulum (ER) to Cytosol through the ER-associated Degradation Pathway
- (2008) Marion Duriez et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Autophagosome formation from membrane compartments enriched in phosphatidylinositol 3-phosphate and dynamically connected to the endoplasmic reticulum
- (2008) Elizabeth L. Axe et al. JOURNAL OF CELL BIOLOGY
- Identification of Proteins Associating with Glycosylphosphatidylinositol- Anchored T-Cadherin on the Surface of Vascular Endothelial Cells: Role for Grp78/BiP in T-Cadherin-Dependent Cell Survival
- (2008) M. Philippova et al. MOLECULAR AND CELLULAR BIOLOGY
- The unfolded protein response signals through high-order assembly of Ire1
- (2008) Alexei V. Korennykh et al. NATURE
- Pten null prostate tumorigenesis and AKT activation are blocked by targeted knockout of ER chaperone GRP78/BiP in prostate epithelium
- (2008) Y. Fu et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Initiation and elongation in fibrillation of ALS-linked superoxide dismutase
- (2008) M. Chattopadhyay et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Decreased enzyme activities of chaperones PDI and BiP in aged mouse livers
- (2007) Jonathan E. Nuss et al. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
Create your own webinar
Interested in hosting your own webinar? Check the schedule and propose your idea to the Peeref Content Team.
Create NowAsk a Question. Answer a Question.
Quickly pose questions to the entire community. Debate answers and get clarity on the most important issues facing researchers.
Get Started