Interactions between mitochondrial reactive oxygen species and cellular glucose metabolism

Targeting thioredoxin-1 with siRNA exacerbates oxidative stress injury after cerebral ischemia/reperfusion in rats

(2015) L. Li et al.   NEUROSCIENCE

Mitochondria are required for ATM activation by extranuclear oxidative stress in cultured human hepatoblastoma cell line Hep G2 cells

(2014) Akinori Morita et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

The H+-ATP synthase: A gate to ROS-mediated cell death or cell survival

(2014) Inmaculada Martínez-Reyes et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOENERGETICS

Genetic deletion of the mitochondrial phosphate carrier desensitizes the mitochondrial permeability transition pore and causes cardiomyopathy

(2014) J Q Kwong et al.   CELL DEATH AND DIFFERENTIATION

The 2-Oxoacid Dehydrogenase Complexes in Mitochondria Can Produce Superoxide/Hydrogen Peroxide at Much Higher Rates Than Complex I

(2014) Casey L. Quinlan et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Genetic manipulation of the cardiac mitochondrial phosphate carrier does not affect permeability transition

(2014) Manuel Gutiérrez-Aguilar et al.   JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY

The ‘mitoflash’ probe cpYFP does not respond to superoxide

(2014) Markus Schwarzländer et al.   NATURE

AMPK: Regulating Energy Balance at the Cellular and Whole Body Levels

(2014) D. Grahame Hardie et al.   PHYSIOLOGY

Photo-Induction and Automated Quantification of Reversible Mitochondrial Permeability Transition Pore Opening in Primary Mouse Myotubes

(2014) Lionel Blanchet et al.   PLoS One

An uncoupling channel within the c-subunit ring of the F1FO ATP synthase is the mitochondrial permeability transition pore

(2014) K. N. Alavian et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Role of GLUT1 in regulation of reactive oxygen species

(2014) Stanley Andrisse et al.   Redox Biology

The C Ring of the F1Fo ATP Synthase Forms the Mitochondrial Permeability Transition Pore: A Critical Appraisal

(2014) Andrew P. Halestrap   Frontiers in Oncology

Partitioning of superoxide and hydrogen peroxide production by mitochondrial respiratory complex I

(2013) Vera G. Grivennikova et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOENERGETICS

Q-site inhibitor induced ROS production of mitochondrial complex II is attenuated by TCA cycle dicarboxylates

(2013) Ilka Siebels et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOENERGETICS

Role of AMPK-mediated adaptive responses in human cells with mitochondrial dysfunction to oxidative stress

(2013) Shi-Bei Wu et al.   BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS

Role of the c subunit of the FOATP synthase in mitochondrial permeability transition

(2013) Massimo Bonora et al.   CELL CYCLE

Glutathionylation of α-ketoglutarate dehydrogenase: The chemical nature and relative susceptibility of the cofactor lipoic acid to modification

(2013) Aaron L. McLain et al.   FREE RADICAL BIOLOGY AND MEDICINE

Mitochondrial glutathione depletion reveals a novel role for the pyruvate dehydrogenase complex as a key H2O2-emitting source under conditions of nutrient overload

(2013) Kelsey H. Fisher-Wellman et al.   FREE RADICAL BIOLOGY AND MEDICINE

Resveratrol Suppresses Cancer Cell Glucose Uptake by Targeting Reactive Oxygen Species-Mediated Hypoxia-Inducible Factor-1  Activation

(2013) K.-H. Jung et al.   JOURNAL OF NUCLEAR MEDICINE

Superoxide constitutes a major signal of mitochondrial superoxide flash

(2013) Xing Zhang et al.   LIFE SCIENCES

AMPK-Dependent Degradation of TXNIP upon Energy Stress Leads to Enhanced Glucose Uptake via GLUT1

(2013) Ning Wu et al.   MOLECULAR CELL

ATM and GLUT1-S490 Phosphorylation Regulate GLUT1 Mediated Transport in Skeletal Muscle

(2013) Stanley Andrisse et al.   PLoS One

Dimers of mitochondrial ATP synthase form the permeability transition pore

(2013) V. Giorgio et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Sites of reactive oxygen species generation by mitochondria oxidizing different substrates

(2013) Casey L. Quinlan et al.   Redox Biology

Redox regulation of mitochondrial function with emphasis on cysteine oxidation reactions

(2013) Ryan J. Mailloux et al.   Redox Biology

Strategic localization of heart mitochondrial NOS: a review of the evidence

(2012) Tamara Zaobornyj et al.   AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY

Trolox-Sensitive Reactive Oxygen Species Regulate Mitochondrial Morphology, Oxidative Phosphorylation and Cytosolic Calcium Handling in Healthy Cells

(2012) Felix Distelmaier et al.   ANTIOXIDANTS & REDOX SIGNALING

Stomatin interacts with GLUT1/SLC2A1, band 3/SLC4A1, and aquaporin-1 in human erythrocyte membrane domains

(2012) Stefanie Rungaldier et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES

Physiological Roles of the Permeability Transition Pore

(2012) Catherine Brenner et al.   CIRCULATION RESEARCH

OXPHOS mutations and neurodegeneration

(2012) Werner J H Koopman et al.   EMBO JOURNAL

Native rates of superoxide production from multiple sites in isolated mitochondria measured using endogenous reporters

(2012) Casey L. Quinlan et al.   FREE RADICAL BIOLOGY AND MEDICINE

Protein thiyl radical mediates S-glutathionylation of complex I

(2012) Patrick T. Kang et al.   FREE RADICAL BIOLOGY AND MEDICINE

Reversible inactivation of dihydrolipoamide dehydrogenase by mitochondrial hydrogen peroxide

(2012) Liang-Jun Yan et al.   FREE RADICAL RESEARCH

A Refined Analysis of Superoxide Production by Mitochondrialsn-Glycerol 3-Phosphate Dehydrogenase

(2012) Adam L. Orr et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Mitochondrial Complex II Can Generate Reactive Oxygen Species at High Rates in Both the Forward and Reverse Reactions

(2012) Casey L. Quinlan et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

What comes first, misshape or dysfunction? The view from metabolic excess

(2012) Chad A. Galloway et al.   JOURNAL OF GENERAL PHYSIOLOGY

Primary fibroblasts of NDUFS4−/− mice display increased ROS levels and aberrant mitochondrial morphology

(2012) Federica Valsecchi et al.   MITOCHONDRION

Physiological Roles of Mitochondrial Reactive Oxygen Species

(2012) Laura A. Sena et al.   MOLECULAR CELL

Monogenic Mitochondrial Disorders

(2012) Werner J.H. Koopman et al.   NEW ENGLAND JOURNAL OF MEDICINE

Mitochondrial ‘flashes’: a radical concept repHined

(2012) Markus Schwarzländer et al.   TRENDS IN CELL BIOLOGY

Reactive oxygen species downregulate glucose transport system in retinal endothelial cells

(2011) Rosa Fernandes et al.   AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY

Mechanisms of Altered Redox Regulation in Neurodegenerative Diseases—Focus on S-Glutathionylation

(2011) Elizabeth A. Sabens Liedhegner et al.   ANTIOXIDANTS & REDOX SIGNALING

Redox Regulation of Mitochondrial Function

(2011) Diane E. Handy et al.   ANTIOXIDANTS & REDOX SIGNALING

Silencing of nicotinamide nucleotide transhydrogenase impairs cellular redox homeostasis and energy metabolism in PC12 cells

(2011) Fei Yin et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOENERGETICS

AMPK-mediated increase of glycolysis as an adaptive response to oxidative stress in human cells: Implication of the cell survival in mitochondrial diseases

(2011) Shi-Bei Wu et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

Cysteine 203 of Cyclophilin D Is Critical for Cyclophilin D Activation of the Mitochondrial Permeability Transition Pore

(2011) Tiffany T. Nguyen et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Glutathionylation Acts as a Control Switch for Uncoupling Proteins UCP2 and UCP3

(2011) Ryan J. Mailloux et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Evidence for Two Sites of Superoxide Production by Mitochondrial NADH-Ubiquinone Oxidoreductase (Complex I)

(2011) Jason R. Treberg et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The roles of phosphate and the phosphate carrier in the mitochondrial permeability transition pore

(2011) Pinadda Varanyuwatana et al.   MITOCHONDRION

Hypoxia Triggers AMPK Activation through Reactive Oxygen Species-Mediated Activation of Calcium Release-Activated Calcium Channels

(2011) P. T. Mungai et al.   MOLECULAR AND CELLULAR BIOLOGY

High-Glucose Stimulation Increases Reactive Oxygen Species Production Through the Calcium and Mitogen-Activated Protein Kinase-Mediated Activation of Mitochondrial Fission

(2010) Tianzheng Yu et al.   ANTIOXIDANTS & REDOX SIGNALING

Cysteine sulfenic Acid as an Intermediate in Disulfide Bond Formation and Nonenzymatic Protein Folding

(2010) Douglas S. Rehder et al.   BIOCHEMISTRY

Signaling Functions of Reactive Oxygen Species

(2010) Henry Jay Forman et al.   BIOCHEMISTRY

Differential localization of ATM is correlated with activation of distinct downstream signaling pathways

(2010) Angela Alexander et al.   CELL CYCLE

Use of Cells Expressing γ Subunit Variants to Identify Diverse Mechanisms of AMPK Activation

(2010) Simon A. Hawley et al.   Cell Metabolism

Oxidative Stress and Diabetic Complications

(2010) Ferdinando Giacco et al.   CIRCULATION RESEARCH

Reactive Oxygen Species and Antioxidants in the Pathophysiology of Cardiovascular Disease: Does the Actual Knowledge Justify a Clinical Approach?

(2010) Salvatore Rosa et al.   Current Vascular Pharmacology

The Natural Protective Mechanism Against Hyperglycemia in Vascular Endothelial Cells: Roles of the Lipid Peroxidation Product 4-Hydroxydodecadienal and Peroxisome Proliferator-Activated Receptor  

(2010) Y. Riahi et al.   DIABETES

Reactive oxygen species and uncoupling protein 2 in pancreatic β-cell function

(2010) J. Pi et al.   DIABETES OBESITY & METABOLISM

ATM activates the pentose phosphate pathway promoting anti-oxidant defence and DNA repair

(2010) Claudia Cosentino et al.   EMBO JOURNAL

Uncoupling protein-3 lowers reactive oxygen species production in isolated mitochondria

(2010) Laurence J. Toime et al.   FREE RADICAL BIOLOGY AND MEDICINE

Regulation of glycolysis and expression of glucose metabolism-related genes by reactive oxygen species in contracting skeletal muscle cells

(2010) Carlos Hermano da Justa Pinheiro et al.   FREE RADICAL BIOLOGY AND MEDICINE

α-Ketoglutarate dehydrogenase: A mitochondrial redox sensor

(2010) Aaron L. McLain et al.   FREE RADICAL RESEARCH

Glutathionylation of Adenine Nucleotide Translocase Induced by Carbon Monoxide Prevents Mitochondrial Membrane Permeabilization and Apoptosis

(2010) Cláudia S. F. Queiroga et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Regulation of Mitochondrial Glutathione Redox Status and Protein Glutathionylation by Respiratory Substrates

(2010) Jerome Garcia et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Exposure to Hydrogen Peroxide Induces Oxidation and Activation of AMP-activated Protein Kinase

(2010) Jaroslaw W. Zmijewski et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Inhibition of lactate dehydrogenase A induces oxidative stress and inhibits tumor progression

(2010) A. Le et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Energy sensing by the AMP-activated protein kinase and its effects on muscle metabolism

(2010) D. Grahame Hardie   PROCEEDINGS OF THE NUTRITION SOCIETY

ATM Activation by Oxidative Stress

(2010) Z. Guo et al.   SCIENCE

Will the original glucose transporter isoform please stand up!

(2009) Anthony Carruthers et al.   AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM

Skeletal muscle glucose uptake during contraction is regulated by nitric oxide and ROS independently of AMPK

(2009) Troy L. Merry et al.   AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM

Mammalian Mitochondrial Complex I: Biogenesis, Regulation, and Reactive Oxygen Species Generation

(2009) Werner J.H. Koopman et al.   ANTIOXIDANTS & REDOX SIGNALING

Redox characterization of human cyclophilin D: Identification of a new mammalian mitochondrial redox sensor?

(2009) Dominique Linard et al.   ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS

Mitochondrial pathways for ROS formation and myocardial injury: the relevance of p66Shc and monoamine oxidase

(2009) Fabio Di Lisa et al.   BASIC RESEARCH IN CARDIOLOGY

Mitochondrial peroxiredoxin involvement in antioxidant defence and redox signalling

(2009) Andrew G. Cox et al.   BIOCHEMICAL JOURNAL

UCP2, not a physiologically relevant uncoupler but a glucose sparing switch impacting ROS production and glucose sensing

(2009) Frédéric Bouillaud   BIOCHIMICA ET BIOPHYSICA ACTA-BIOENERGETICS

Focus on mammalian thioredoxin reductases — Important selenoproteins with versatile functions

(2009) Elias S.J. Arnér   BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS

Protection of a single-cysteine redox switch from oxidative destruction: On the functional role of sulfenyl amide formation in the redox-regulated enzyme PTP1B

(2009) Santhosh Sivaramakrishnan et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

A critical evaluation of cpYFP as a probe for superoxide

(2009) Florian L. Muller   FREE RADICAL BIOLOGY AND MEDICINE

Hypoxic activation of AMPK is dependent on mitochondrial ROS but independent of an increase in AMP/ATP ratio

(2009) Brooke M. Emerling et al.   FREE RADICAL BIOLOGY AND MEDICINE

Thioredoxin-independent Regulation of Metabolism by the α-Arrestin Proteins

(2009) Parth Patwari et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Uncoupling protein 2 regulates reactive oxygen species formation in islets and influences susceptibility to diabetogenic action of streptozotocin

(2009) Simon C Lee et al.   JOURNAL OF ENDOCRINOLOGY

Stretch-stimulated glucose uptake in skeletal muscle is mediated by reactive oxygen species and p38 MAP-kinase

(2009) Melissa A. Chambers et al.   JOURNAL OF PHYSIOLOGY-LONDON

Regulation of mitochondrial biogenesis during myogenesis

(2009) A.H.V. Remels et al.   MOLECULAR AND CELLULAR ENDOCRINOLOGY

Impaired glucose transporter-1 degradation and increased glucose transport and oxidative stress in response to high glucose in chondrocytes from osteoarthritic versus normal human cartilage

(2009) Susana C Rosa et al.   ARTHRITIS RESEARCH & THERAPY

Oxidative stress stimulates skeletal muscle glucose uptake through a phosphatidylinositol 3-kinase-dependent pathway

(2008) Yasuki Higaki et al.   AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM

An essential role for the Glut1 PDZ-binding motif in growth factor regulation of Glut1 degradation and trafficking

(2008) Heather L. Wieman et al.   BIOCHEMICAL JOURNAL

How mitochondria produce reactive oxygen species

(2008) Michael P. Murphy   BIOCHEMICAL JOURNAL

Oxidative Stress Is Inherent in Prostate Cancer Cells and Is Required for Aggressive Phenotype

(2008) B. Kumar et al.   CANCER RESEARCH

Reactive oxygen species stabilize hypoxia-inducible factor-1 alpha protein and stimulate transcriptional activity via AMP-activated protein kinase in DU145 human prostate cancer cells

(2008) Seung-Nam Jung et al.   CARCINOGENESIS

Superoxide Flashes in Single Mitochondria

(2008) Wang Wang et al.   CELL

Rapid Activation of Akt2 Is Sufficient to Stimulate GLUT4 Translocation in 3T3-L1 Adipocytes

(2008) Yvonne Ng et al.   Cell Metabolism

Thiol chemistry and specificity in redox signaling

(2008) Christine C. Winterbourn et al.   FREE RADICAL BIOLOGY AND MEDICINE

Nox-generated ROS modulate glucose uptake in a leukaemic cell line

(2008) Cecilia Prata et al.   FREE RADICAL RESEARCH

Essential Role for Uncoupling Protein-3 in Mitochondrial Adaptation to Fasting but Not in Fatty Acid Oxidation or Fatty Acid Anion Export

(2008) Erin L. Seifert et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Protein Tyrosine Nitration of the Flavin Subunit Is Associated with Oxidative Modification of Mitochondrial Complex II in the Post-ischemic Myocardium

(2008) Chwen-Lih Chen et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Complex I within Oxidatively Stressed Bovine Heart Mitochondria Is Glutathionylated on Cys-531 and Cys-704 of the 75-kDa Subunit

(2008) Thomas R. Hurd et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Discovery of TBC1D1 as an Insulin-, AICAR-, and Contraction-stimulated Signaling Nexus in Mouse Skeletal Muscle

(2008) Eric B. Taylor et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

AMPK α1 Activation Is Required for Stimulation of Glucose Uptake by Twitch Contraction, but Not by H2O2, in Mouse Skeletal Muscle

(2008) Thomas E. Jensen et al.   PLoS One

Glucose sensing by MondoA:Mlx complexes: A role for hexokinases and direct regulation of thioredoxin-interacting protein expression

(2008) C. A. Stoltzman et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

NAD+/NADH and NADP+/NADPH in Cellular Functions and Cell Death: Regulation and Biological Consequences

(2007) Weihai Ying   ANTIOXIDANTS & REDOX SIGNALING