Endoplasmic Reticulum Stress and Associated ROS

TGF-β improves myocardial function and prevents apoptosis induced by anoxia–reoxygenation, through the reduction of endoplasmic reticulum stress

(2016) Yufeng Wang et al.   CANADIAN JOURNAL OF PHYSIOLOGY AND PHARMACOLOGY

Aluminum Activates PERK-EIF2α Signaling and Inflammatory Proteins in Human Neuroblastoma SH-SY5Y Cells

(2015) Syed Husain Mustafa Rizvi et al.   BIOLOGICAL TRACE ELEMENT RESEARCH

Crocin and quercetin prevent PAT-induced apoptosis in mammalian cells: Involvement of ROS-mediated ER stress pathway

(2015) Manel Boussabbeh et al.   ENVIRONMENTAL TOXICOLOGY

Polypeptide from Chlamys farreri suppresses ultraviolet-B irradiation-induced apoptosis through restoring ER redox homeostasis, scavenging ROS generation, and suppressing the PERK-eIF2a-CHOP pathway in HaCaT cells

(2015) Feng Zhong et al.   JOURNAL OF PHOTOCHEMISTRY AND PHOTOBIOLOGY B-BIOLOGY

α-Synuclein-mediated inhibition of ATF6 processing into COPII vesicles disrupts UPR signaling in Parkinson's disease

(2015) Joel J. Credle et al.   NEUROBIOLOGY OF DISEASE

Fucosylated chondroitin sulphate from Cusumaria frondosa mitigates hepatic endoplasmic reticulum stress and inflammation in insulin resistant mice

(2015) Shijie Li et al.   Food & Function

Lycopene Protects against Hypoxia/Reoxygenation Injury by Alleviating ER Stress Induced Apoptosis in Neonatal Mouse Cardiomyocytes

(2015) Jiqian Xu et al.   PLoS One

Is Glycemic Control Modulating Endoplasmic Reticulum Stress in Leukocytes of Type 2 Diabetic Patients?

(2014) Susana Rovira-Llopis et al.   ANTIOXIDANTS & REDOX SIGNALING

Endoplasmic Reticulum Stress and Oxidative Stress in Cell Fate Decision and Human Disease

(2014) Stewart Siyan Cao et al.   ANTIOXIDANTS & REDOX SIGNALING

BRCA1 And Estrogen/Estrogen Receptor In Breast Cancer: Where They Interact?

(2014) Li Wang et al.   International Journal of Biological Sciences

Control of dopaminergic neuron survival by the unfolded protein response transcription factor XBP1

(2014) P. Valdes et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Getting RIDD of RNA: IRE1 in cell fate regulation

(2014) M. Maurel et al.   TRENDS IN BIOCHEMICAL SCIENCES

Pharmacological Studies on Neurodegenerative Diseases Focusing on Refolding and Degradation of Unfolded Proteins in the Endoplasmic Reticulum

(2014) Yasuyuki Nomura   YAKUGAKU ZASSHI-JOURNAL OF THE PHARMACEUTICAL SOCIETY OF JAPAN

Nutrient deprivation induces α-synuclein aggregation through endoplasmic reticulum stress response and SREBP2 pathway

(2014) Peizhou Jiang et al.   Frontiers in Aging Neuroscience

When supply does not meet demand-ER stress and plant programmed cell death

(2014) Brett Williams et al.   Frontiers in Plant Science

Endoplasmic Reticulum Stress and Nox-Mediated Reactive Oxygen Species Signaling in the Peripheral Vasculature: Potential Role in Hypertension

(2013) Celio X.C. Santos et al.   ANTIOXIDANTS & REDOX SIGNALING

A 28-kDa Splice Variant of NADPH Oxidase-4 Is Nuclear-Localized and Involved in Redox Signaling in Vascular Cells

(2013) Narayana Anilkumar et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

ER stress-induced cell death mechanisms

(2013) Renata Sano et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

Stress-inducible phosphoprotein 1 has unique cochaperone activity during development and regulates cellular response to ischemia via the prion protein

(2013) Flavio H. Beraldo et al.   FASEB JOURNAL

Endoplasmic Reticulum Stress Sensing in the Unfolded Protein Response

(2013) B. M. Gardner et al.   Cold Spring Harbor Perspectives in Biology

Endoplasmic Reticulum Stress, Pancreatic  -Cell Degeneration, and Diabetes

(2013) F. R. Papa   Cold Spring Harbor Perspectives in Medicine

Structural Insights into the Redox-Regulated Dynamic Conformations of Human Protein Disulfide Isomerase

(2012) Chao Wang et al.   ANTIOXIDANTS & REDOX SIGNALING

The NADPH Oxidase Family and its Inhibitors

(2012) Paulina Kleniewska et al.   ARCHIVUM IMMUNOLOGIAE ET THERAPIAE EXPERIMENTALIS

IRE1, a Double-Edged Sword in Pre-miRNA Slicing and Cell Death

(2012) Justin Hassler et al.   DEVELOPMENTAL CELL

Upregulated function of mitochondria-associated ER membranes in Alzheimer disease

(2012) Estela Area-Gomez et al.   EMBO JOURNAL

Amelioration of Glucolipotoxicity-Induced Endoplasmic Reticulum Stress by a “Chemical Chaperone” in Human THP-1 Monocytes

(2012) Raji Lenin et al.   Experimental Diabetes Research

Protein disulfide isomerase in redox cell signaling and homeostasis

(2012) Francisco R.M. Laurindo et al.   FREE RADICAL BIOLOGY AND MEDICINE

An Involvement of Oxidative Stress in Endoplasmic Reticulum Stress and Its Associated Diseases

(2012) Bidur Bhandary et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Generation of superoxide anions by a glycation reaction in conventional laboratory media

(2012) Takuji Nakashima et al.   JOURNAL OF BIOSCIENCE AND BIOENGINEERING

ProteinS-glutathionylation enhances Ca2+-induced Ca2+release via the IP3receptor in cultured aortic endothelial cells

(2012) Jeffrey T. Lock et al.   JOURNAL OF PHYSIOLOGY-LONDON

Macrophage paraoxonase 2 regulates calcium homeostasis and cell survival under endoplasmic reticulum stress conditions and is sufficient to prevent the development of aggravated atherosclerosis in paraoxonase 2 deficiency/apoE−/− mice on a Western diet

(2012) Asokan Devarajan et al.   MOLECULAR GENETICS AND METABOLISM

A protective mutation

(2012) Bart De Strooper et al.   NATURE

A mutation in APP protects against Alzheimer’s disease and age-related cognitive decline

(2012) Thorlakur Jonsson et al.   NATURE

ATF6alpha Promotes Astroglial Activation and Neuronal Survival in a Chronic Mouse Model of Parkinson’s Disease

(2012) Koji Hashida et al.   PLoS One

Antioxidants as potential therapeutics for neuropsychiatric disorders

(2012) Chirayu D. Pandya et al.   PROGRESS IN NEURO-PSYCHOPHARMACOLOGY & BIOLOGICAL PSYCHIATRY

ER stress-induced inflammation: does it aid or impede disease progression?

(2012) Abhishek D. Garg et al.   TRENDS IN MOLECULAR MEDICINE

Molecular Pharmacological Studies on the Protection Mechanism against Endoplasmic Reticulum Stress-induced Neurodegenerative Disease

(2012) Masayuki Kaneko   YAKUGAKU ZASSHI-JOURNAL OF THE PHARMACEUTICAL SOCIETY OF JAPAN

Endoplasmic Reticulum Stress in UMOD-Related Kidney Disease: A Human Pathologic Study

(2011) Julien Adam et al.   AMERICAN JOURNAL OF KIDNEY DISEASES

Protein Folding and Modification in the Mammalian Endoplasmic Reticulum

(2011) Ineke Braakman et al.   Annual Review of Biochemistry

PrPC displays an essential protective role from oxidative stress in an astrocyte cell line derived from PrPC knockout mice

(2011) Fernanda R. Bertuchi et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Mitochondria-targeted Antioxidants Protect Pancreatic β-cells against Oxidative Stress and Improve Insulin Secretion in Glucotoxicity and Glucolipotoxicity

(2011) Sangbin Lim et al.   CELLULAR PHYSIOLOGY AND BIOCHEMISTRY

Acute caffeine ingestion enhances strength performance and reduces perceived exertion and muscle pain perception during resistance exercise

(2011) Michael J. Duncan et al.   European Journal of Sport Science

The roles of ER stress and P450 2E1 in CCl4-induced steatosis

(2011) Geum-Hwa Lee et al.   INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY

Functionalin VitroAnalysis of the ERO1 Protein and Protein-disulfide Isomerase Pathway

(2011) Kazutaka Araki et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Human Protein-disulfide Isomerase Is a Redox-regulated Chaperone Activated by Oxidation of Domain a′

(2011) Chao Wang et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

IRE1-Dependent Activation of AMPK in Response to Nitric Oxide

(2011) G. P. Meares et al.   MOLECULAR AND CELLULAR BIOLOGY

Transgenic Expression of Entire Hepatitis B Virus in Mice Induces Hepatocarcinogenesis Independent of Chronic Liver Injury

(2011) Bing Na et al.   PLoS One

The Endoplasmic Reticulum Stress Response and Aging

(2011) Nirinjini Naidoo   REVIEWS IN THE NEUROSCIENCES

The Unfolded Protein Response: From Stress Pathway to Homeostatic Regulation

(2011) P. Walter et al.   SCIENCE

Unfolded Proteins Are Ire1-Activating Ligands That Directly Induce the Unfolded Protein Response

(2011) B. M. Gardner et al.   SCIENCE

Redox Regulation of Endothelial Canonical Transient Receptor Potential Channels

(2010) Donna L. Cioffi   ANTIOXIDANTS & REDOX SIGNALING

Dietary Antioxidants and Long-term Risk of Dementia

(2010) Elizabeth E. Devore et al.   ARCHIVES OF NEUROLOGY

Constitutive NADPH-Dependent Electron Transferase Activity of the Nox4 Dehydrogenase Domain

(2010) Yukio Nisimoto et al.   BIOCHEMISTRY

Diabetes as a disease of endoplasmic reticulum stress

(2010) Sally E. Thomas et al.   DIABETES-METABOLISM RESEARCH AND REVIEWS

Modulation of Endoplasmic Reticulum Ca2+Store Filling by Cyclic ADP-ribose Promotes Inositol Trisphosphate (IP3)-evoked Ca2+Signals

(2010) Michiko Yamasaki-Mann et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Nox4-Derived H2O2 Mediates Endoplasmic Reticulum Signaling through Local Ras Activation

(2010) R.-F. Wu et al.   MOLECULAR AND CELLULAR BIOLOGY

Protective effects of galantamine against Aβ-induced PC12 cell apoptosis by preventing mitochondrial dysfunction and endoplasmic reticulum stress

(2010) Xiaoyu Liu et al.   NEUROCHEMISTRY INTERNATIONAL

The oxysterol 27-hydroxycholesterol increases β-amyloid and oxidative stress in retinal pigment epithelial cells

(2010) Bhanu Dasari et al.   BMC Ophthalmology

The Unfolded Protein Response Is Activated in Pretangle Neurons in Alzheimer's Disease Hippocampus

(2009) Jeroen J.M. Hoozemans et al.   AMERICAN JOURNAL OF PATHOLOGY

Mechanisms and Implications of Reactive Oxygen Species Generation During the Unfolded Protein Response: Roles of Endoplasmic Reticulum Oxidoreductases, Mitochondrial Electron Transport, and NADPH Oxidase

(2009) Célio X.C. Santos et al.   ANTIOXIDANTS & REDOX SIGNALING

Role of ERO1-α–mediated stimulation of inositol 1,4,5-triphosphate receptor activity in endoplasmic reticulum stress–induced apoptosis

(2009) Gang Li et al.   JOURNAL OF CELL BIOLOGY

Membrane expansion alleviates endoplasmic reticulum stress independently of the unfolded protein response

(2009) Sebastian Schuck et al.   JOURNAL OF CELL BIOLOGY

Regulated Ire1-dependent decay of messenger RNAs in mammalian cells

(2009) Julie Hollien et al.   JOURNAL OF CELL BIOLOGY

Bax inhibitor 1 regulates ER-stress-induced ROS accumulation through the regulation of cytochrome P450 2E1

(2009) H.-R. Kim et al.   JOURNAL OF CELL SCIENCE

Protein disulfide isomerase (PDI) associates with NADPH oxidase and is required for phagocytosis of Leishmania chagasi promastigotes by macrophages

(2009) Célio X. C. Santos et al.   JOURNAL OF LEUKOCYTE BIOLOGY

Valproate, a Mood Stabilizer, Induces WFS1 Expression and Modulates Its Interaction with ER Stress Protein GRP94

(2009) Chihiro Kakiuchi et al.   PLoS One

How mitochondria produce reactive oxygen species

(2008) Michael P. Murphy   BIOCHEMICAL JOURNAL

NOX family NADPH oxidases in liver and in pancreatic islets: a role in the metabolic syndrome and diabetes?

(2008) Cécile Guichard et al.   BIOCHEMICAL SOCIETY TRANSACTIONS

Real-Time Redox Measurements during Endoplasmic Reticulum Stress Reveal Interlinked Protein Folding Functions

(2008) Philip I. Merksamer et al.   CELL

Roles of IP3R and RyR Ca2+ Channels in Endoplasmic Reticulum Stress and  -Cell Death

(2008) D. S. Luciani et al.   DIABETES

Mouse models of cystathionine β-synthase deficiency reveal significant threshold effects of hyperhomocysteinemia

(2008) Sapna Gupta et al.   FASEB JOURNAL

Oxidative stress markers in bipolar disorder: A meta-analysis

(2008) Ana C. Andreazza et al.   JOURNAL OF AFFECTIVE DISORDERS

Altered PI3-Kinase/Akt Signalling in Skeletal Muscle of Young Men with Low Birth Weight

(2008) Christine B. Jensen et al.   PLoS One

Antioxidants reduce endoplasmic reticulum stress and improve protein secretion

(2008) J. D. Malhotra et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA