Endoplasmic reticulum stress aggravates copper-induced apoptosis via the PERK/ATF4/CHOP signaling pathway in duck renal tubular epithelial cells

Copper sulfate-induced endoplasmic reticulum stress promotes hepatic apoptosis by activating CHOP, JNK and caspase-12 signaling pathways

(2020) Hongbin Wu et al.   ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY

Copper induce zebrafish retinal developmental defects via triggering stresses and apoptosis

(2020) Guang Zhao et al.   Cell Communication and Signaling

Selenium mitigates cadmium-induced crosstalk between autophagy and endoplasmic reticulum stress via regulating calcium homeostasis in avian leghorn male hepatoma (LMH) cells

(2020) Cong Zhang et al.   ENVIRONMENTAL POLLUTION

Selenium prevent cadmium-induced hepatotoxicity through modulation of endoplasmic reticulum-resident selenoproteins and attenuation of endoplasmic reticulum stress

(2020) Cong Zhang et al.   ENVIRONMENTAL POLLUTION

Natural Products Targeting ER Stress, and the Functional Link to Mitochondria

(2020) Stefania Martucciello et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Molecular Insights of Copper Sulfate Exposure-Induced Nephrotoxicity: Involvement of Oxidative and Endoplasmic Reticulum Stress Pathways

(2020) Chongshan Dai et al.   Biomolecules

Ecotoxicity of trace elements to chicken GALLUS gallus domesticus exposed to a gradient of polymetallic-polluted sites.

(2020) Sameh EL. Kribi-Boukhris et al.   ENVIRONMENTAL POLLUTION

Borax Alleviates Copper-Induced Renal Injury via Inhibiting the DNA Damage and Apoptosis in Rainbow Trout

(2019) Gonca Alak et al.   BIOLOGICAL TRACE ELEMENT RESEARCH

Regulation of apoptosis in health and disease: the balancing act of BCL-2 family proteins

(2019) Rumani Singh et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

The unfolded protein response modulators GSK2606414 and KIRA6 are potent KIT inhibitors

(2019) Mohamed Mahameed et al.   Cell Death & Disease

MicroRNA-222 reprogrammed cancer-associated fibroblasts enhance growth and metastasis of breast cancer

(2019) Annesha Chatterjee et al.   BRITISH JOURNAL OF CANCER

Destruction of redox and mitochondrial dynamics co-contributes to programmed cell death in chicken kidney under arsenite or/and copper (II) exposure

(2019) Hongjing Zhao et al.   ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY

G-Protein-Coupled Estrogen Receptor (GPER)-Specific Agonist G1 Induces ER Stress Leading to Cell Death in MCF-7 Cells

(2019) Diep-Khanh Ho Vo et al.   Biomolecules

Endoplasmic Reticulum Stress Induced by Toxic Elements—a Review of Recent Developments

(2019) S. V. S. Rana   BIOLOGICAL TRACE ELEMENT RESEARCH

Caspase-8 Regulates Endoplasmic Reticulum Stress-Induced Necroptosis Independent of the Apoptosis Pathway in Auditory Cells

(2019) Kishino et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Butylated hydroxytoluene induces dysregulation of calcium homeostasis and endoplasmic reticulum stress resulting in mouse Leydig cell death

(2019) Jiyeon Ham et al.   ENVIRONMENTAL POLLUTION

Molybdenum and cadmium co-induce oxidative stress and apoptosis through mitochondria-mediated pathway in duck renal tubular epithelial cells

(2019) Chang Wang et al.   JOURNAL OF HAZARDOUS MATERIALS

Excessive ER stress and the resulting autophagic flux dysfunction contribute to fluoride-induced neurotoxicity

(2018) Qiang Niu et al.   ENVIRONMENTAL POLLUTION

Leishmania donovani induced Unfolded Protein Response delays host cell apoptosis in PERK dependent manner

(2018) Kumar Abhishek et al.   PLoS Neglected Tropical Diseases

Endoplasmic reticulum stress, the unfolded protein response and autophagy in kidney diseases

(2017) Andrey V. Cybulsky   Nature Reviews Nephrology

Copper or/and arsenic induce oxidative stress-cascaded, nuclear factor kappa B-dependent inflammation and immune imbalance, trigging heat shock response in the kidney of chicken

(2017) Yu Wang et al.   Oncotarget

Endoplasmic reticulum stress and disturbed calcium homeostasis are involved in copper-induced alteration in hepatic lipid metabolism in yellow catfish Pelteobagrus fulvidraco

(2016) Yu-Feng Song et al.   CHEMOSPHERE

Copper induces hepatocyte injury due to the endoplasmic reticulum stress in cultured cells and patients with Wilson disease

(2016) Shinji Oe et al.   EXPERIMENTAL CELL RESEARCH

Long and short (timeframe) of endoplasmic reticulum stress-induced cell death

(2016) Hyung Don Ryoo   FEBS Journal

Attenuation of PKR-like ER Kinase (PERK) Signaling Selectively Controls Endoplasmic Reticulum Stress-induced Inflammation Without Compromising Immunological Responses

(2016) Lauren N. Guthrie et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Cell death induced by endoplasmic reticulum stress

(2015) Raffaella Iurlaro et al.   FEBS Journal

Targeting copper in cancer therapy: ‘Copper That Cancer’

(2015) Delphine Denoyer et al.   Metallomics

Copper: toxicological relevance and mechanisms

(2014) Lisa M. Gaetke et al.   ARCHIVES OF TOXICOLOGY

Histopathological effects of waterborne copper nanoparticles and copper sulphate on the organs of rainbow trout (Oncorhynchus mykiss)

(2012) Genan A. Al-Bairuty et al.   AQUATIC TOXICOLOGY

Discovery of 7-Methyl-5-(1-{[3-(trifluoromethyl)phenyl]acetyl}-2,3-dihydro-1H-indol-5-yl)-7H-pyrrolo[2,3-d]pyrimidin-4-amine (GSK2606414), a Potent and Selective First-in-Class Inhibitor of Protein Kinase R (PKR)-like Endoplasmic Reticulum Kinase (PERK)

(2012) Jeffrey M. Axten et al.   JOURNAL OF MEDICINAL CHEMISTRY

The unfolded protein response: controlling cell fate decisions under ER stress and beyond

(2012) Claudio Hetz   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Role of Endoplasmic Reticulum Stress in Metabolic Disease and Other Disorders

(2011) Lale Ozcan et al.   Annual Review of Medicine

Astaxanthin Induces Mitochondria-Mediated Apoptosis in Rat Hepatocellular Carcinoma CBRH-7919 Cells

(2011) Xiao-dong Song et al.   BIOLOGICAL & PHARMACEUTICAL BULLETIN

Integrating the mechanisms of apoptosis induced by endoplasmic reticulum stress

(2011) Ira Tabas et al.   NATURE CELL BIOLOGY

The Unfolded Protein Response: From Stress Pathway to Homeostatic Regulation

(2011) P. Walter et al.   SCIENCE

Nano-copper induces oxidative stress and apoptosis in kidney via both extrinsic and intrinsic pathways

(2011) Abhijit Sarkar et al.   TOXICOLOGY

Role of Oxidative Stress, Apoptosis, and Intracellular Homeostasis in Primary Cultures of Rat Proximal Tubular Cells Exposed to Cadmium

(2008) Lin Wang et al.   BIOLOGICAL TRACE ELEMENT RESEARCH