G-Protein-Coupled Estrogen Receptor (GPER)-Specific Agonist G1 Induces ER Stress Leading to Cell Death in MCF-7 Cells

Estrogen-Related Hormones Induce Apoptosis by Stabilizing Schlafen-12 Protein Turnover

(2019) Dianrong Li et al.   MOLECULAR CELL

Zearalenone induces apoptosis in bovine mammary epithelial cells by activating endoplasmic reticulum stress

(2019) YuRong Fu et al.   JOURNAL OF DAIRY SCIENCE

G-protein-coupled estrogen receptor GPER-1 expression in hormone receptor-positive breast cancer is associated with poor benefit of tamoxifen

(2018) Tanja Ignatov et al.   BREAST CANCER RESEARCH AND TREATMENT

Epigenetic down regulation of G protein-coupled estrogen receptor (GPER) functions as a tumor suppressor in colorectal cancer

(2017) Qiao Liu et al.   Molecular Cancer

High neuronatin (NNAT) expression is associated with poor outcome in breast cancer

(2017) Norbert Nass et al.   VIRCHOWS ARCHIV

Targeting calcium signaling in cancer therapy

(2017) Chaochu Cui et al.   Acta Pharmaceutica Sinica B

Ultrasound-targeted microbubble destruction of calcium channel subunit α 1D siRNA inhibits breast cancer via G protein-coupled receptor 30

(2016) Yanlei Ji et al.   ONCOLOGY REPORTS

24(S)-Hydroxycholesterol induces RIPK1-dependent but MLKL-independent cell death in the absence of caspase-8

(2015) Diep-Khanh Ho Vo et al.   STEROIDS

New insights into the roles of CHOP-induced apoptosis in ER stress

(2014) Yiming Li et al.   ACTA BIOCHIMICA ET BIOPHYSICA SINICA

GPER-mediated proliferation and estradiol production in breast cancer-associated fibroblasts

(2014) Haojun Luo et al.   ENDOCRINE-RELATED CANCER

GPER functions as a tumor suppressor in MCF-7 and SK-BR-3 breast cancer cells

(2014) Christine Weißenborn et al.   JOURNAL OF CANCER RESEARCH AND CLINICAL ONCOLOGY

GPER functions as a tumor suppressor in triple-negative breast cancer cells

(2014) Christine Weißenborn et al.   JOURNAL OF CANCER RESEARCH AND CLINICAL ONCOLOGY

The PERK pathway independently triggers apoptosis and a Rac1/Slpr/JNK/Dilp8 signaling favoring tissue homeostasis in a chronic ER stress Drosophila model

(2014) Y Demay et al.   Cell Death & Disease

The activation of G protein-coupled receptor 30 (GPR30) inhibits proliferation of estrogen receptor-negative breast cancer cells in vitro and in vivo

(2014) W Wei et al.   Cell Death & Disease

GPER Mediates Estrogen-Induced Signaling and Proliferation in Human Breast Epithelial Cells and Normal and Malignant Breast

(2014) Allison L. Scaling et al.   Hormones & Cancer

GPER Function in Breast Cancer: An Overview

(2014) Rosamaria Lappano et al.   Frontiers in Endocrinology

ER stress-induced cell death mechanisms

(2013) Renata Sano et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

GPER-1 Expression Decreases During Breast Cancer Tumorigenesis

(2013) Tanja Ignatov et al.   CANCER INVESTIGATION

Oleuropein and hydroxytyrosol activate GPER/ GPR30-dependent pathways leading to apoptosis of ER-negative SKBR3 breast cancer cells

(2013) Adele Chimento et al.   MOLECULAR NUTRITION & FOOD RESEARCH

GPER-1 acts as a tumor suppressor in ovarian cancer

(2013) Tanja Ignatov et al.   Journal of Ovarian Research

Cholesterol homeostasis: a key to prevent or slow down neurodegeneration

(2013) Laura Anchisi et al.   Frontiers in Physiology

The unfolded protein response: controlling cell fate decisions under ER stress and beyond

(2012) Claudio Hetz   NATURE REVIEWS MOLECULAR CELL BIOLOGY

G-protein-coupled estrogen receptor GPR30 and tamoxifen resistance in breast cancer

(2011) Atanas Ignatov et al.   BREAST CANCER RESEARCH AND TREATMENT

PARP-1 cleavage fragments: signatures of cell-death proteases in neurodegeneration

(2011) Ganta Chaitanya et al.   Cell Communication and Signaling

The GPER1 Agonist G-1 Attenuates Endothelial Cell Proliferation by Inhibiting DNA Synthesis and Accumulating Cells in the S and G2 Phases of the Cell Cycle

(2011) Anders Holm et al.   JOURNAL OF VASCULAR RESEARCH

The G Protein-Coupled Receptor GPR30 Inhibits Proliferation of Estrogen Receptor-Positive Breast Cancer Cells

(2010) E. A. Ariazi et al.   CANCER RESEARCH

Activation of GPR30 inhibits the growth of prostate cancer cells through sustained activation of Erk1/2, c-jun/c-fos-dependent upregulation of p21 and induction of G2 cell-cycle arrest

(2010) Q K Y Chan et al.   CELL DEATH AND DIFFERENTIATION

Role of GPR30 in the mechanisms of tamoxifen resistance in breast cancer MCF-7 cells

(2009) Atanas Ignatov et al.   BREAST CANCER RESEARCH AND TREATMENT

GPR30 and estrogen receptor expression: new insights into hormone dependence of inflammatory breast cancer

(2009) Hugo Arias-Pulido et al.   BREAST CANCER RESEARCH AND TREATMENT

Role of ERO1-α–mediated stimulation of inositol 1,4,5-triphosphate receptor activity in endoplasmic reticulum stress–induced apoptosis

(2009) Gang Li et al.   JOURNAL OF CELL BIOLOGY

Calcium/calmodulin-dependent protein kinase II links ER stress with Fas and mitochondrial apoptosis pathways

(2009) Jenelle M. Timmins et al.   JOURNAL OF CLINICAL INVESTIGATION

SUnSET, a nonradioactive method to monitor protein synthesis

(2009) Enrico K Schmidt et al.   NATURE METHODS

GPR30/GPER1: searching for a role in estrogen physiology

(2009) Björn Olde et al.   TRENDS IN ENDOCRINOLOGY AND METABOLISM

Curcumin and cancer: An “old-age” disease with an “age-old” solution

(2008) Preetha Anand et al.   CANCER LETTERS

How IRE1 Reacts to ER Stress

(2008) David Ron et al.   CELL