Homology-directed repair protects the replicating genome from metabolic assaults

Title
Homology-directed repair protects the replicating genome from metabolic assaults
Authors
Keywords
homology-directed repair, ribonucleotide reductase, hypoxia, reactive oxygen species, nascent DNA degradation, translesion DNA synthesis, cancer evolution, BRCA1/2, replication stress, genome instability
Journal
DEVELOPMENTAL CELL
Volume 56, Issue 4, Pages 461-477.e7
Publisher
Elsevier BV
Online
2021-02-23
DOI
10.1016/j.devcel.2021.01.011

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