Nanobiomaterial-based vaccination immunotherapy of cancer

Personal neoantigen vaccines induce persistent memory T cell responses and epitope spreading in patients with melanoma

(2021) Zhuting Hu et al.   NATURE MEDICINE

A Hybrid Eukaryotic-Prokaryotic Nanoplatform with Photothermal Modality for Enhanced Antitumor Vaccination

(2020) Qi Chen et al.   ADVANCED MATERIALS

Molecular Imaging for Cancer Immunotherapy: Seeing Is Believing

(2020) Madiha Saeed et al.   BIOCONJUGATE CHEMISTRY

Peptide–TLR-7/8a conjugate vaccines chemically programmed for nanoparticle self-assembly enhance CD8 T-cell immunity to tumor antigens

(2020) Geoffrey M. Lynn et al.   NATURE BIOTECHNOLOGY

Engineered immunogen binding to alum adjuvant enhances humoral immunity

(2020) Tyson J. Moyer et al.   NATURE MEDICINE

In situ genetic engineering of tumors for long-lasting and systemic immunotherapy

(2020) Stephany Y. Tzeng et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The biology, function, and biomedical applications of exosomes

(2020) Raghu Kalluri et al.   SCIENCE

An RNA vaccine drives expansion and efficacy of claudin-CAR-T cells against solid tumors

(2020) Katharina Reinhard et al.   SCIENCE

Engineered probiotics for local tumor delivery of checkpoint blockade nanobodies

(2020) Candice R. Gurbatri et al.   Science Translational Medicine

Artificial Mini Dendritic Cells Boost T Cell–Based Immunotherapy for Ovarian Cancer

(2020) Shanshan Cheng et al.   Advanced Science

In Vivo Assembly of Nanoparticles Achieved through Synergy of Structure‐Based Protein Engineering and Synthetic DNA Generates Enhanced Adaptive Immunity

(2020) Ziyang Xu et al.   Advanced Science

Enhanced Ferroptosis by Oxygen-Boosted Phototherapy Based on a 2-in-1 Nanoplatform of Ferrous Hemoglobin for Tumor Synergistic Therapy

(2020) Tian Xu et al.   ACS Nano

Injectable dual-scale mesoporous silica cancer vaccine enabling efficient delivery of antigen/adjuvant-loaded nanoparticles to dendritic cells recruited in local macroporous scaffold

(2020) Thanh Loc Nguyen et al.   BIOMATERIALS

Mimetic Heat Shock Protein Mediated Immune Process to Enhance Cancer Immunotherapy

(2020) Xue Li et al.   NANO LETTERS

Engineering Polymeric Prodrug Nanoplatform for Vaccination Immunotherapy of Cancer

(2020) Lei Zhou et al.   NANO LETTERS

Analyzing the Mycobacterium tuberculosis immune response by T-cell receptor clustering with GLIPH2 and genome-wide antigen screening

(2020) Huang Huang et al.   NATURE BIOTECHNOLOGY

A vaccine-based nanosystem for initiating innate immunity and improving tumor immunotherapy

(2020) Di-Wei Zheng et al.   Nature Communications

Co-delivery of Peptide Neoantigens and Stimulator of Interferon Genes Agonists Enhances Response to Cancer Vaccines

(2020) Daniel Shae et al.   ACS Nano

Engineered Cell‐Membrane‐Coated Nanoparticles Directly Present Tumor Antigens to Promote Anticancer Immunity

(2020) Yao Jiang et al.   ADVANCED MATERIALS

Bacterial outer membrane vesicles as a platform for biomedical applications: An update

(2020) Min Li et al.   JOURNAL OF CONTROLLED RELEASE

Adaptive Nanoparticle Platforms for High Throughput Expansion and Detection of Antigen-Specific T cells

(2020) John W. Hickey et al.   NANO LETTERS

Programmable multistage drug delivery to lymph nodes

(2020) Alex Schudel et al.   Nature Nanotechnology

Tumour sensitization via the extended intratumoural release of a STING agonist and camptothecin from a self-assembled hydrogel

(2020) Feihu Wang et al.   Nature Biomedical Engineering

Bacterial Vesicle-Cancer Cell Hybrid Membrane-Coated Nanoparticles for Tumor Specific Immune Activation and Photothermal Therapy

(2020) Dongdong Wang et al.   ACS Applied Materials & Interfaces

Enhanced Cancer DNA Vaccine via Direct Transfection to Host Dendritic Cells Recruited in Injectable Scaffolds

(2020) Thanh Loc Nguyen et al.   ACS Nano

Synergistic tumor immunological strategy by combining tumor nanovaccine with gene-mediated extracellular matrix scavenger

(2020) Yingying Hu et al.   BIOMATERIALS

Proton-driven transformable nanovaccine for cancer immunotherapy

(2020) Ningqiang Gong et al.   Nature Nanotechnology

A tumor-to-lymph procedure navigated versatile gel system for combinatorial therapy against tumor recurrence and metastasis

(2020) Lin Qin et al.   Science Advances

Nanoparticle-enhanced chemo-immunotherapy to trigger robust antitumor immunity

(2020) Jingjing Liang et al.   Science Advances

An implantable blood clot–based immune niche for enhanced cancer vaccination

(2020) Qin Fan et al.   Science Advances

Engineering nanoparticulate vaccines for enhancing antigen cross-presentation

(2020) Guangsheng Du et al.   CURRENT OPINION IN BIOTECHNOLOGY

A Modular Vaccine Platform Combining Self-Assembled Peptide Cages and Immunogenic Peptides

(2019) Caroline Morris et al.   ADVANCED FUNCTIONAL MATERIALS

Antigens reversibly conjugated to a polymeric glyco-adjuvant induce protective humoral and cellular immunity

(2019) D. Scott Wilson et al.   NATURE MATERIALS

Delivery technologies for cancer immunotherapy

(2019) Rachel S. Riley et al.   NATURE REVIEWS DRUG DISCOVERY

Vaccinia virus-mediated cancer immunotherapy: cancer vaccines and oncolytics

(2019) Zong Sheng Guo et al.   Journal for ImmunoTherapy of Cancer

Tumors and Their Microenvironment Dual‐Targeting Chemotherapy with Local Immune Adjuvant Therapy for Effective Antitumor Immunity against Breast Cancer

(2019) Caifeng Deng et al.   Advanced Science

Delivering the Messenger: Advances in Technologies for Therapeutic mRNA Delivery

(2019) Piotr S. Kowalski et al.   MOLECULAR THERAPY

Nanovaccine based on a protein-delivering dendrimer for effective antigen cross-presentation and cancer immunotherapy

(2019) Jun Xu et al.   BIOMATERIALS

Tumor Microenvironment-Activatable Prodrug Vesicles for Nanoenabled Cancer Chemoimmunotherapy Combining Immunogenic Cell Death Induction and CD47 Blockade

(2019) Fangyuan Zhou et al.   ADVANCED MATERIALS

Smart pH-Responsive Nanocube-Controlled Delivery of DNA Vaccine and Chemotherapeutic Drugs for Chemoimmunotherapy

(2019) Huu Thuy Trang Duong et al.   ACS Applied Materials & Interfaces

Combining Nanomedicine and Immunotherapy

(2019) Yang Shi et al.   ACCOUNTS OF CHEMICAL RESEARCH

Engineering Magnetosomes for Ferroptosis/Immunomodulation Synergism in Cancer

(2019) Fan Zhang et al.   ACS Nano

Viromimetic STING Agonist‐Loaded Hollow Polymeric Nanoparticles for Safe and Effective Vaccination against Middle East Respiratory Syndrome Coronavirus

(2019) Leon Chien‐Wei Lin et al.   ADVANCED FUNCTIONAL MATERIALS

An aluminum adjuvant-integrated nano-MOF as antigen delivery system to induce strong humoral and cellular immune responses

(2019) Xiaofang Zhong et al.   JOURNAL OF CONTROLLED RELEASE

Cancer DNA vaccines: current preclinical and clinical developments and future perspectives

(2019) Alessandra Lopes et al.   JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH

Nanoenabled Modulation of Acidic Tumor Microenvironment Reverses Anergy of Infiltrating T Cells and Potentiates Anti-PD-1 Therapy

(2019) Yu-Xue Zhang et al.   NANO LETTERS

PD-1+ regulatory T cells amplified by PD-1 blockade promote hyperprogression of cancer

(2019) Takahiro Kamada et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Visualization of early events in mRNA vaccine delivery in non-human primates via PET–CT and near-infrared imaging

(2019) Kevin E. Lindsay et al.   Nature Biomedical Engineering

High Co-loading Capacity and Stimuli-Responsive Release Based on Cascade Reaction of Self-Destructive Polymer for Improved Chemo-Photodynamic Therapy

(2019) Menglin Wang et al.   ACS Nano

Overview of recent advances in liposomal nanoparticle-based cancer immunotherapy

(2019) Ang Gao et al.   ACTA PHARMACOLOGICA SINICA

Organic Semiconducting Pro-nanostimulants for Near-Infrared Photoactivatable Cancer Immunotherapy

(2019) Jingchao Li et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Lipid nanoparticles for delivery of messenger RNA to the back of the eye

(2019) Siddharth Patel et al.   JOURNAL OF CONTROLLED RELEASE

Therapeutic mRNA delivery to leukocytes

(2019) Yasmin Granot-Matok et al.   JOURNAL OF CONTROLLED RELEASE

Cytomembrane nanovaccines show therapeutic effects by mimicking tumor cells and antigen presenting cells

(2019) Wen-Long Liu et al.   Nature Communications

Engineering nanoparticles to locally activate T cells in the tumor microenvironment

(2019) Dangge Wang et al.   Science Immunology

Development of an In Situ Cancer Vaccine via Combinational Radiation and Bacterial‐Membrane‐Coated Nanoparticles

(2019) Ravi B. Patel et al.   ADVANCED MATERIALS

A Designer Scaffold with Immune Nanoconverters for Reverting Immunosuppression and Enhancing Immune Checkpoint Blockade Therapy

(2019) Hathaichanok Phuengkham et al.   ADVANCED MATERIALS

Self‐Amplified Drug Delivery with Light‐Inducible Nanocargoes to Enhance Cancer Immunotherapy

(2019) Bing Feng et al.   ADVANCED MATERIALS

Opposing Functions of Interferon Coordinate Adaptive and Innate Immune Responses to Cancer Immune Checkpoint Blockade

(2019) Joseph L. Benci et al.   CELL

Peptides as cancer vaccines

(2019) Marta Calvo Tardón et al.   CURRENT OPINION IN PHARMACOLOGY

Neoantigen vaccine: an emerging tumor immunotherapy

(2019) Miao Peng et al.   Molecular Cancer

Delivery of mRNA vaccines with heterocyclic lipids increases anti-tumor efficacy by STING-mediated immune cell activation

(2019) Lei Miao et al.   NATURE BIOTECHNOLOGY

Immunization with mannosylated nanovaccines and inhibition of the immune-suppressing microenvironment sensitizes melanoma to immune checkpoint modulators

(2019) João Conniot et al.   Nature Nanotechnology

Neoantigen quality, not quantity

(2019) Nicholas McGranahan et al.   Science Translational Medicine

Mucosal Immunization with a pH-Responsive Nanoparticle Vaccine Induces Protective CD8+ Lung-Resident Memory T Cells

(2019) Frances C. Knight et al.   ACS Nano

Recent Progress in Ferroptosis Inducers for Cancer Therapy

(2019) Chen Liang et al.   ADVANCED MATERIALS

Engineering anti-cancer nanovaccine based on antigen cross-presentation

(2019) Vaishnavi U. Warrier et al.   BIOSCIENCE REPORTS

Developing neoantigen-targeted T cell–based treatments for solid tumors

(2019) Tori N. Yamamoto et al.   NATURE MEDICINE

Tailoring mRNA Vaccine to Balance Innate/Adaptive Immune Response

(2019) Sergio Linares-Fernández et al.   TRENDS IN MOLECULAR MEDICINE

Engineering dendritic cell vaccines to improve cancer immunotherapy

(2019) Caleb R. Perez et al.   Nature Communications

A cell-free biosynthesis platform for modular construction of protein glycosylation pathways

(2019) Weston Kightlinger et al.   Nature Communications

Oncolytic adenovirus programmed by synthetic gene circuit for cancer immunotherapy

(2019) Huiya Huang et al.   Nature Communications

Red blood cell–derived nanoerythrosome for antigen delivery with enhanced cancer immunotherapy

(2019) Xiao Han et al.   Science Advances

Co-localized delivery of nanomedicine and nanovaccine augments the postoperative cancer immunotherapy by amplifying T-cell responses

(2019) Xiang Liu et al.   BIOMATERIALS

Albumin-based cancer therapeutics for intraperitoneal drug delivery: a review

(2019) Leen Van de Sande et al.   DRUG DELIVERY

Development of novel nanoantibiotics using an outer membrane vesicle-based drug efflux mechanism

(2019) Weiwei Huang et al.   JOURNAL OF CONTROLLED RELEASE

Peptide-Based Multiepitopic Vaccine Platforms via Click Reactions

(2019) Mar Forner et al.   JOURNAL OF ORGANIC CHEMISTRY

Sheddable Prodrug Vesicles Combating Adaptive Immune Resistance for Improved Photodynamic Immunotherapy of Cancer

(2019) Ang Gao et al.   NANO LETTERS

Bioengineering Bacterial Vesicle-Coated Polymeric Nanomedicine for Enhanced Cancer Immunotherapy and Metastasis Prevention

(2019) Qi Chen et al.   NANO LETTERS

Intratumoral injection of the seasonal flu shot converts immunologically cold tumors to hot and serves as an immunotherapy for cancer

(2019) Jenna H. Newman et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Artificially cloaked viral nanovaccine for cancer immunotherapy

(2019) Manlio Fusciello et al.   Nature Communications

Cancer Cell Membrane-Coated Adjuvant Nanoparticles with Mannose Modification for Effective Anticancer Vaccination

(2018) Rong Yang et al.   ACS Nano

Bioinspired Stimuli-Responsive Color-Changing Systems

(2018) Golnaz Isapour et al.   ADVANCED MATERIALS

Cell Membrane Bioconjugation and Membrane-Derived Nanomaterials for Immunotherapy

(2018) Peter Y. Li et al.   BIOCONJUGATE CHEMISTRY

Necroptotic cancer cells-mimicry nanovaccine boosts anti-tumor immunity with tailored immune-stimulatory modality

(2018) Ting Kang et al.   BIOMATERIALS

Personalized neoantigen vaccines: A new approach to cancer immunotherapy

(2018) Amanda R. Aldous et al.   BIOORGANIC & MEDICINAL CHEMISTRY

Asymmetric mesoporous silica nanoparticles as potent and safe immunoadjuvants provoke high immune responses

(2018) Prasanna Lakshmi Abbaraju et al.   CHEMICAL COMMUNICATIONS

Making anti-cytokine therapy more selective: Studies in mice

(2018) Marina S. Drutskaya et al.   CYTOKINE

Navigating albumin-based nanoparticles through various drug delivery routes

(2018) Yeong L. Tan et al.   DRUG DISCOVERY TODAY

Polymer-coated viral vectors: hybrid nanosystems for gene therapy

(2018) Pratheppa Rajagopal et al.   JOURNAL OF GENE MEDICINE

Non-viral gene delivery systems for tissue repair and regeneration

(2018) Pan Wu et al.   Journal of Translational Medicine

Separating T Cell Targeting Components onto Magnetically Clustered Nanoparticles Boosts Activation

(2018) Alyssa K. Kosmides et al.   NANO LETTERS

Lipid Nanoparticle Formulations for Enhanced Co-delivery of siRNA and mRNA

(2018) Rebecca L. Ball et al.   NANO LETTERS

IL-7 and CCL19 expression in CAR-T cells improves immune cell infiltration and CAR-T cell survival in the tumor

(2018) Keishi Adachi et al.   NATURE BIOTECHNOLOGY

A facile approach to enhance antigen response for personalized cancer vaccination

(2018) Aileen Weiwei Li et al.   NATURE MATERIALS

Exploiting the pliability and lateral mobility of Pickering emulsion for enhanced vaccination

(2018) Yufei Xia et al.   NATURE MATERIALS

Understanding the tumor immune microenvironment (TIME) for effective therapy

(2018) Mikhail Binnewies et al.   NATURE MEDICINE

mRNA vaccines — a new era in vaccinology

(2018) Norbert Pardi et al.   NATURE REVIEWS DRUG DISCOVERY

Enhanced mRNA delivery into lymphocytes enabled by lipid-varied libraries of charge-altering releasable transporters

(2018) Colin J. McKinlay et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Personalized vaccines for cancer immunotherapy

(2018) Ugur Sahin et al.   SCIENCE

Improving Vaccine and Immunotherapy Design Using Biomaterials

(2018) Michelle L. Bookstaver et al.   TRENDS IN IMMUNOLOGY

Immunoengineering with biomaterials for enhanced cancer immunotherapy

(2018) Yu-Qing Xie et al.   Wiley Interdisciplinary Reviews-Nanomedicine and Nanobiotechnology

A cancer vaccine-mediated postoperative immunotherapy for recurrent and metastatic tumors

(2018) Tingting Wang et al.   Nature Communications

Human in vivo-generated monocyte-derived dendritic cells and macrophages cross-present antigens through a vacuolar pathway

(2018) Tsing-Lee Tang-Huau et al.   Nature Communications

Advances and Opportunities in Nanoparticle- and Nanomaterial-Based Vaccines against Bacterial Infections

(2018) Leon Chien-Wei Lin et al.   Advanced Healthcare Materials

Lymph Node-Targeting Nanovaccine through Antigen-CpG Self-Assembly Potentiates Cytotoxic T Cell Activation

(2018) Xiaobo Xi et al.   Journal of Immunology Research

Neoantigen Vaccine Delivery for Personalized Anticancer Immunotherapy

(2018) Yugang Guo et al.   Frontiers in Immunology

PEGylated tumor cell membrane vesicles as a new vaccine platform for cancer immunotherapy

(2018) Lukasz J. Ochyl et al.   BIOMATERIALS

Smart vaccine delivery based on microneedle arrays decorated with ultra-pH-responsive copolymers for cancer immunotherapy

(2018) Huu Thuy Trang Duong et al.   BIOMATERIALS

Efficient magnetic enrichment of antigen-specific T cells by engineering particle properties

(2018) John W. Hickey et al.   BIOMATERIALS

Mannose-functionalized Nanoscaffolds for Targeted Delivery in Biomedical Applications

(2018) Jian Yin et al.   Chemistry-An Asian Journal

Personalized Tumor RNA Loaded Lipid-Nanoparticles Prime the Systemic and Intratumoral Milieu for Response to Cancer Immunotherapy

(2018) Elias J. Sayour et al.   NANO LETTERS

Crumpled Aluminum Hydroxide Nanostructures as a Microenvironment Dysregulation Agent for Cancer Treatment

(2018) Marat I. Lerner et al.   NANO LETTERS

Robust prediction of response to immune checkpoint blockade therapy in metastatic melanoma

(2018) Noam Auslander et al.   NATURE MEDICINE

Serum albumin nanoparticles vaccine provides protection against a lethal Pseudomonas aeruginosa challenge

(2018) Stella Maria de Souza Morais et al.   VACCINE

Cationic lipid-assisted nanoparticles for delivery of mRNA cancer vaccine

(2018) Ya-Nan Fan et al.   Biomaterials Science

Exosomes: The next generation of endogenous nanomaterials for advanced drug delivery and therapy

(2018) Wen Liao et al.   Acta Biomaterialia

Large-Pore Mesoporous-Silica-Coated Upconversion Nanoparticles as Multifunctional Immunoadjuvants with Ultrahigh Photosensitizer and Antigen Loading Efficiency for Improved Cancer Photodynamic Immunotherapy

(2018) Binbin Ding et al.   ADVANCED MATERIALS

Cancer Neoantigens

(2018) Ton N. Schumacher et al.   Annual Review of Immunology

Efficient mRNA delivery system utilizing chimeric VSVG-L7Ae virus-like particles

(2018) Yulia Zhitnyuk et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Cytokines in clinical cancer immunotherapy

(2018) Pedro Berraondo et al.   BRITISH JOURNAL OF CANCER

Stimuli-Responsive Therapeutic Metallodrugs

(2018) Xiaohui Wang et al.   CHEMICAL REVIEWS

Modular core-shell polymeric nanoparticles mimicking viral structures for vaccination

(2018) Bo Lou et al.   JOURNAL OF CONTROLLED RELEASE

Cancer immunoediting and resistance to T cell-based immunotherapy

(2018) Jake S. O’Donnell et al.   Nature Reviews Clinical Oncology

Cell specific delivery of modified mRNA expressing therapeutic proteins to leukocytes

(2018) Nuphar Veiga et al.   Nature Communications

Engineered outer membrane vesicle is potent to elicit HPV16E7-specific cellular immunity in a mouse model of TC-1 graft tumor

(2017) Shijie Wang et al.   International Journal of Nanomedicine

Lymph node targeting strategies to improve vaccination efficacy

(2017) Hao Jiang et al.   JOURNAL OF CONTROLLED RELEASE

Chitosan-zein nano-in-microparticles capable of mediating in vivo transgene expression following oral delivery

(2017) Eric Farris et al.   JOURNAL OF CONTROLLED RELEASE

Dendritic cell-derived exosomes elicit tumor regression in autochthonous hepatocellular carcinoma mouse models

(2017) Zhen Lu et al.   JOURNAL OF HEPATOLOGY

Boosting Intracellular Delivery of Lipid Nanoparticle-Encapsulated mRNA

(2017) Siddharth Patel et al.   NANO LETTERS

Cell membrane coated nanoparticles: next-generation therapeutics

(2017) Ashwin Narain et al.   Nanomedicine

Cancer immunotherapy

(2017) Eric Bender   NATURE

An immunogenic personal neoantigen vaccine for patients with melanoma

(2017) Patrick A. Ott et al.   NATURE

A STING-activating nanovaccine for cancer immunotherapy

(2017) Min Luo et al.   Nature Nanotechnology

Antigen-capturing nanoparticles improve the abscopal effect and cancer immunotherapy

(2017) Yuanzeng Min et al.   Nature Nanotechnology

Immunotherapy: Cancer vaccines on the move

(2017) Jacques Banchereau et al.   Nature Reviews Clinical Oncology

Chimeric antigen receptor T-cell therapy — assessment and management of toxicities

(2017) Sattva S. Neelapu et al.   Nature Reviews Clinical Oncology

Radiotherapy and immunotherapy: a beneficial liaison?

(2017) Ralph R. Weichselbaum et al.   Nature Reviews Clinical Oncology

DNA vaccines for prostate cancer

(2017) Christopher D. Zahm et al.   PHARMACOLOGY & THERAPEUTICS

Sec61 blockade by mycolactone inhibits antigen cross-presentation independently of endosome-to-cytosol export

(2017) Jeff E. Grotzke et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Surface-Engineering of Red Blood Cells as Artificial Antigen Presenting Cells Promising for Cancer Immunotherapy

(2017) Xiaoqi Sun et al.   Small

Dissolving Microneedle Arrays for Transdermal Delivery of Amphiphilic Vaccines

(2017) Myunggi An et al.   Small

Outer membrane vesicles harboring modified lipid A moiety augment the efficacy of an influenza vaccine exhibiting reduced endotoxicity in a mouse model

(2017) Tae-Young Lee et al.   VACCINE

Platform technologies for modern vaccine manufacturing

(2017) Hayley K. Charlton Hume et al.   VACCINE

Bacterial outer membrane vesicles suppress tumor by interferon-γ-mediated antitumor response

(2017) Oh Youn Kim et al.   Nature Communications

Nano-enabled pancreas cancer immunotherapy using immunogenic cell death and reversing immunosuppression

(2017) Jianqin Lu et al.   Nature Communications

Albumin/vaccine nanocomplexes that assemble in vivo for combination cancer immunotherapy

(2017) Guizhi Zhu et al.   Nature Communications

Strategies for Preparing Albumin-based Nanoparticles for Multifunctional Bioimaging and Drug Delivery

(2017) Fei-Fei An et al.   Theranostics

Radionuclide I-131 Labeled Albumin-Paclitaxel Nanoparticles for Synergistic Combined Chemo-radioisotope Therapy of Cancer

(2017) Longlong Tian et al.   Theranostics

Recent Advances of Activatable Molecular Probes Based on Semiconducting Polymer Nanoparticles in Sensing and Imaging

(2017) Yan Lyu et al.   Advanced Science

Cancer Cell Membrane–Biomimetic Nanoparticles for Homologous-Targeting Dual-Modal Imaging and Photothermal Therapy

(2016) Ze Chen et al.   ACS Nano

Polymer-Lipid Nanoparticles for Systemic Delivery of mRNA to the Lungs

(2016) James C. Kaczmarek et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Immune targets and neoantigens for cancer immunotherapy and precision medicine

(2016) Rong-Fu Wang et al.   CELL RESEARCH

Degradable Controlled-Release Polymers and Polymeric Nanoparticles: Mechanisms of Controlling Drug Release

(2016) Nazila Kamaly et al.   CHEMICAL REVIEWS

Materials for non-viral intracellular delivery of messenger RNA therapeutics

(2016) Kevin J. Kauffman et al.   JOURNAL OF CONTROLLED RELEASE

Lipid Nanoparticle Assisted mRNA Delivery for Potent Cancer Immunotherapy

(2016) Matthias A. Oberli et al.   NANO LETTERS

Systemic RNA delivery to dendritic cells exploits antiviral defence for cancer immunotherapy

(2016) Lena M. Kranz et al.   NATURE

Designer vaccine nanodiscs for personalized cancer immunotherapy

(2016) Rui Kuai et al.   NATURE MATERIALS

Stimuli-Responsive Self-Assembled DNA Nanomaterials for Biomedical Applications

(2016) Ziwen Dai et al.   Small

Assessment of outer membrane vesicles of periodontopathic bacterium Porphyromonas gingivalis as possible mucosal immunogen

(2016) Ryoma Nakao et al.   VACCINE

Presenting native-like trimeric HIV-1 antigens with self-assembling nanoparticles

(2016) Linling He et al.   Nature Communications

Photothermal therapy with immune-adjuvant nanoparticles together with checkpoint blockade for effective cancer immunotherapy

(2016) Qian Chen et al.   Nature Communications

Designing hydrogels for controlled drug delivery

(2016) Jianyu Li et al.   Nature Reviews Materials

Novel adjuvant Alum-TLR7 significantly potentiates immune response to glycoconjugate vaccines

(2016) Cecilia Buonsanti et al.   Scientific Reports

Real-Time Monitoring of ATP-Responsive Drug Release Using Mesoporous-Silica-Coated Multicolor Upconversion Nanoparticles

(2015) Jinping Lai et al.   ACS Nano

Cancer immunotherapy: harnessing the immune system to battle cancer

(2015) Yiping Yang   JOURNAL OF CLINICAL INVESTIGATION

Cell membrane-camouflaged nanoparticles for drug delivery

(2015) Brian T. Luk et al.   JOURNAL OF CONTROLLED RELEASE

Expression kinetics of nucleoside-modified mRNA delivered in lipid nanoparticles to mice by various routes

(2015) Norbert Pardi et al.   JOURNAL OF CONTROLLED RELEASE

Using exosomes, naturally-equipped nanocarriers, for drug delivery

(2015) Elena V. Batrakova et al.   JOURNAL OF CONTROLLED RELEASE

Engineered materials for cancer immunotherapy

(2015) Alexander S. Cheung et al.   Nano Today

In vivo characterization of the physicochemical properties of polymer-linked TLR agonists that enhance vaccine immunogenicity

(2015) Geoffrey M Lynn et al.   NATURE BIOTECHNOLOGY

In situ vaccination with cowpea mosaic virus nanoparticles suppresses metastatic cancer

(2015) P. H. Lizotte et al.   Nature Nanotechnology

Biodegradable Nanoellipsoidal Artificial Antigen Presenting Cells for Antigen Specific T-Cell Activation

(2015) Randall A. Meyer et al.   Small

Cancer vaccines in the new era of cancer immunotherapy

(2015) Keith L. Knutson et al.   VACCINE

RNA-Based Vaccines in Cancer Immunotherapy

(2015) Megan A. McNamara et al.   Journal of Immunology Research

Modular Vaccine Design Using Carrier-Free Capsules Assembled from Polyionic Immune Signals

(2015) Yu-Chieh Chiu et al.   ACS Biomaterials-Science & Engineering

Modular Vaccine Design Using Carrier-Free Capsules Assembled from Polyionic Immune Signals

(2015) Yu-Chieh Chiu et al.   ACS Biomaterials Science & Engineering

DNA vaccine for cancer immunotherapy

(2015) Benjamin Yang et al.   Human Vaccines & Immunotherapeutics

Nanoparticle-Based Immunotherapy for Cancer

(2014) Kun Shao et al.   ACS Nano

Programmable Engineering of a Biosensing Interface with Tetrahedral DNA Nanostructures for Ultrasensitive DNA Detection

(2014) Meihua Lin et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Toll-like receptor agonists shape the immune responses to a mannose receptor-targeted cancer vaccine

(2014) Li-Zhen He et al.   Cellular & Molecular Immunology

Advances in lipid-based colloid systems as drug carrier for topic delivery

(2014) Yingjie Zhai et al.   JOURNAL OF CONTROLLED RELEASE

IL-2: The First Effective Immunotherapy for Human Cancer

(2014) S. A. Rosenberg   JOURNAL OF IMMUNOLOGY

Cancer Cell Membrane-Coated Nanoparticles for Anticancer Vaccination and Drug Delivery

(2014) Ronnie H. Fang et al.   NANO LETTERS

Messenger RNA (mRNA) nanoparticle tumour vaccination

(2014) Kyle K. L. Phua et al.   Nanoscale

Structure-based programming of lymph-node targeting in molecular vaccines

(2014) Haipeng Liu et al.   NATURE

Dual and multi-stimuli responsive polymeric nanoparticles for programmed site-specific drug delivery

(2013) Ru Cheng et al.   BIOMATERIALS

Innate and adaptive immune cells in the tumor microenvironment

(2013) Thomas F Gajewski et al.   NATURE IMMUNOLOGY

Stimuli-responsive nanocarriers for drug delivery

(2013) Simona Mura et al.   NATURE MATERIALS

Persistent antigen at vaccination sites induces tumor-specific CD8+ T cell sequestration, dysfunction and deletion

(2013) Yared Hailemichael et al.   NATURE MEDICINE

Toxicity profiling of several common RNAi-based nanomedicines: a comparative study

(2013) Dalit Landesman-Milo et al.   Drug Delivery and Translational Research

Liposomal drug delivery systems: From concept to clinical applications

(2012) Theresa M. Allen et al.   ADVANCED DRUG DELIVERY REVIEWS

Developing mRNA-vaccine technologies

(2012) Thomas Schlake et al.   RNA Biology

Stimulus-Sensitive Polymeric Nanoparticles and Their Applications as Drug and Gene Carriers

(2012) Yi Li et al.   Advanced Healthcare Materials

Overview of the cancer vaccine field

(2012) Alex Kudrin et al.   Human Vaccines & Immunotherapeutics

DNA vaccines: an historical perspective and view to the future

(2010) Margaret A. Liu   IMMUNOLOGICAL REVIEWS

Modular Nucleic Acid Assembled p/MHC Microarrays for Multiplexed Sorting of Antigen-Specific T Cells

(2009) Gabriel A. Kwong et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Methods for the Preparation and Manufacture of Polymeric Nanoparticles

(2008) Christine Vauthier et al.   PHARMACEUTICAL RESEARCH