Nanoparticle-enhanced chemo-immunotherapy to trigger robust antitumor immunity

Top 10 Challenges in Cancer Immunotherapy

(2020) Priti S. Hegde et al.   IMMUNITY

Synthetic Immunogenic Cell Death Mediated by Intracellular Delivery of STING Agonist Nanoshells Enhances Anticancer Chemo-immunotherapy

(2020) Saborni Chattopadhyay et al.   NANO LETTERS

Endosomolytic polymersomes increase the activity of cyclic dinucleotide STING agonists to enhance cancer immunotherapy

(2019) Daniel Shae et al.   Nature Nanotechnology

Approaches to treat immune hot, altered and cold tumours with combination immunotherapies

(2019) Jérôme Galon et al.   NATURE REVIEWS DRUG DISCOVERY

Delivery technologies for cancer immunotherapy

(2019) Rachel S. Riley et al.   NATURE REVIEWS DRUG DISCOVERY

Cancer nanomedicine for combination cancer immunotherapy

(2019) Jutaek Nam et al.   Nature Reviews Materials

Organic Semiconducting Pro-nanostimulants for Near-Infrared Photoactivatable Cancer Immunotherapy

(2019) Jingchao Li et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Cooperation between Constitutive and Inducible Chemokines Enables T Cell Engraftment and Immune Attack in Solid Tumors

(2019) Denarda Dangaj et al.   CANCER CELL

STING pathway agonism as a cancer therapeutic

(2019) Blake A. Flood et al.   IMMUNOLOGICAL REVIEWS

Advances in cancer immunotherapy 2019 – latest trends

(2019) Stephan Kruger et al.   JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH

An inhalable nanoparticulate STING agonist synergizes with radiotherapy to confer long-term control of lung metastases

(2019) Yang Liu et al.   Nature Communications

High Drug Loading and Sub-Quantitative Loading Efficiency of Polymeric Micelles Driven by Donor–Receptor Coordination Interactions

(2018) Shixian Lv et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Disulfide Bond-Driven Oxidation- and Reduction-Responsive Prodrug Nanoassemblies for Cancer Therapy

(2018) Bingjun Sun et al.   NANO LETTERS

Cytokines in clinical cancer immunotherapy

(2018) Pedro Berraondo et al.   BRITISH JOURNAL OF CANCER

The Effect of Topoisomerase I Inhibitors on the Efficacy of T-Cell-Based Cancer Immunotherapy

(2017) Jodi A McKenzie et al.   JNCI-Journal of the National Cancer Institute

Spatial Targeting of Tumor-Associated Macrophages and Tumor Cells with a pH-Sensitive Cluster Nanocarrier for Cancer Chemoimmunotherapy

(2017) Song Shen et al.   NANO LETTERS

Host STING-dependent MDSC mobilization drives extrinsic radiation resistance

(2017) Hua Liang et al.   Nature Communications

The Effect of Topoisomerase I Inhibitors on the Efficacy of T-Cell-Based Cancer Immunotherapy

(2017) Jodi A McKenzie et al.   JNCI-Journal of the National Cancer Institute

Expansion and Activation of CD103 + Dendritic Cell Progenitors at the Tumor Site Enhances Tumor Responses to Therapeutic PD-L1 and BRAF Inhibition

(2016) Hélène Salmon et al.   IMMUNITY

The Role of Micelle Size in Tumor Accumulation, Penetration, and Treatment

(2015) Jinqiang Wang et al.   ACS Nano

Melanoma-intrinsic β-catenin signalling prevents anti-tumour immunity

(2015) Stefani Spranger et al.   NATURE

Cancer nanomedicine: from targeted delivery to combination therapy

(2015) Xiaoyang Xu et al.   TRENDS IN MOLECULAR MEDICINE

Tumour-infiltrating CD4+ and CD8+ lymphocytes as predictors of clinical outcome in glioma

(2014) S Han et al.   BRITISH JOURNAL OF CANCER

DMXAA Causes Tumor Site-Specific Vascular Disruption in Murine Non-Small Cell Lung Cancer, and like the Endogenous Non-Canonical Cyclic Dinucleotide STING Agonist, 2′3′-cGAMP, Induces M2 Macrophage Repolarization

(2014) Charlene M. Downey et al.   PLoS One

Preparation of a Camptothecin Prodrug with Glutathione-Responsive Disulfide Linker for Anticancer Drug Delivery

(2013) Zhigang Xu et al.   Chemistry-An Asian Journal

Up-Regulation of PD-L1, IDO, and Tregs in the Melanoma Tumor Microenvironment Is Driven by CD8+ T Cells

(2013) S. Spranger et al.   Science Translational Medicine

The role of non-covalent interactions in anticancer drug loading and kinetic stability of polymeric micelles

(2012) Chuan Yang et al.   BIOMATERIALS

Combined treatment of human colorectal tumor cell lines with chemotherapeutic agents and ionizing irradiation canin vitroinduce tumor cell death forms with immunogenic potential

(2012) Benjamin Frey et al.   Journal of Immunotoxicology

Intracellular glutathione redox status in human dendritic cells regulates IL-27 production and T-cell polarization

(2011) Y. Kamide et al.   ALLERGY

Chemotherapy Induces Intratumoral Expression of Chemokines in Cutaneous Melanoma, Favoring T-cell Infiltration and Tumor Control

(2011) M. Hong et al.   CANCER RESEARCH