Peptide–TLR-7/8a conjugate vaccines chemically programmed for nanoparticle self-assembly enhance CD8 T-cell immunity to tumor antigens
Published 2020 View Full Article
- Home
- Publications
- Publication Search
- Publication Details
Title
Peptide–TLR-7/8a conjugate vaccines chemically programmed for nanoparticle self-assembly enhance CD8 T-cell immunity to tumor antigens
Authors
Keywords
-
Journal
NATURE BIOTECHNOLOGY
Volume -, Issue -, Pages -
Publisher
Springer Science and Business Media LLC
Online
2020-01-14
DOI
10.1038/s41587-019-0390-x
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- Impact of polymer-TLR-7/8 agonist (adjuvant) morphology on the potency and mechanism of CD8 T cell induction
- (2019) Geoffrey M. Lynn et al. BIOMACROMOLECULES
- Antigens reversibly conjugated to a polymeric glyco-adjuvant induce protective humoral and cellular immunity
- (2019) D. Scott Wilson et al. NATURE MATERIALS
- Induction of anti-cancer T cell immunity by in situ vaccination using systemically administered nanomedicines
- (2019) Geoffrey M. Lynn et al. CANCER LETTERS
- Synthesis and Evaluation of Novel TLR2 Agonists as Potential Adjuvants for Cancer Vaccines
- (2019) Benjamin L. Lu et al. JOURNAL OF MEDICINAL CHEMISTRY
- Engineering patient-specific cancer immunotherapies
- (2019) Lindsay Scheetz et al. Nature Biomedical Engineering
- Toll-like Receptor Agonist Conjugation: A Chemical Perspective
- (2018) Bob J. Ignacio et al. BIOCONJUGATE CHEMISTRY
- A facile approach to enhance antigen response for personalized cancer vaccination
- (2018) Aileen Weiwei Li et al. NATURE MATERIALS
- Personalized vaccines for cancer immunotherapy
- (2018) Ugur Sahin et al. SCIENCE
- Improving Vaccine and Immunotherapy Design Using Biomaterials
- (2018) Michelle L. Bookstaver et al. TRENDS IN IMMUNOLOGY
- Computational Pipeline for the PGV-001 Neoantigen Vaccine Trial
- (2018) Alex Rubinsteyn et al. Frontiers in Immunology
- Poly(propylacrylic acid)-peptide nanoplexes as a platform for enhancing the immunogenicity of neoantigen cancer vaccines
- (2018) Feng Qiu et al. BIOMATERIALS
- COSMIC: the Catalogue Of Somatic Mutations In Cancer
- (2018) John G Tate et al. NUCLEIC ACIDS RESEARCH
- Mass Spectrometry Profiling of HLA-Associated Peptidomes in Mono-allelic Cells Enables More Accurate Epitope Prediction
- (2017) Jennifer G. Abelin et al. IMMUNITY
- Personalized RNA mutanome vaccines mobilize poly-specific therapeutic immunity against cancer
- (2017) Ugur Sahin et al. NATURE
- An immunogenic personal neoantigen vaccine for patients with melanoma
- (2017) Patrick A. Ott et al. NATURE
- Albumin/vaccine nanocomplexes that assemble in vivo for combination cancer immunotherapy
- (2017) Guizhi Zhu et al. Nature Communications
- Designing therapeutic cancer vaccines by mimicking viral infections
- (2016) Hussein Sultan et al. CANCER IMMUNOLOGY IMMUNOTHERAPY
- Vaccination against Oncoproteins of HPV16 for Noninvasive Vulvar/Vaginal Lesions: Lesion Clearance Is Related to the Strength of the T-Cell Response
- (2016) M. I. E. van Poelgeest et al. CLINICAL CANCER RESEARCH
- dbNSFP v3.0: A One-Stop Database of Functional Predictions and Annotations for Human Nonsynonymous and Splice-Site SNVs
- (2016) Xiaoming Liu et al. HUMAN MUTATION
- Synthetic long peptide-based vaccine formulations for induction of cell mediated immunity: A comparative study of cationic liposomes and PLGA nanoparticles
- (2016) Eleni Maria Varypataki et al. JOURNAL OF CONTROLLED RELEASE
- Atezolizumab in patients with locally advanced and metastatic urothelial carcinoma who have progressed following treatment with platinum-based chemotherapy: a single-arm, multicentre, phase 2 trial
- (2016) Jonathan E Rosenberg et al. LANCET
- Systemic RNA delivery to dendritic cells exploits antiviral defence for cancer immunotherapy
- (2016) Lena M. Kranz et al. NATURE
- Designer vaccine nanodiscs for personalized cancer immunotherapy
- (2016) Rui Kuai et al. NATURE MATERIALS
- Protection against malaria at 1 year and immune correlates following PfSPZ vaccination
- (2016) Andrew S Ishizuka et al. NATURE MEDICINE
- Eradication of large established tumors in mice by combination immunotherapy that engages innate and adaptive immune responses
- (2016) Kelly D Moynihan et al. NATURE MEDICINE
- T-Cell Transfer Therapy Targeting Mutant KRAS in Cancer
- (2016) Eric Tran et al. NEW ENGLAND JOURNAL OF MEDICINE
- Ensembl 2017
- (2016) Bronwen L. Aken et al. NUCLEIC ACIDS RESEARCH
- pH-degradable imidazoquinoline-ligated nanogels for lymph node-focused immune activation
- (2016) Lutz Nuhn et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Vaccination during myeloid cell depletion by cancer chemotherapy fosters robust T cell responses
- (2016) Marij J. Welters et al. Science Translational Medicine
- Mutant MHC class II epitopes drive therapeutic immune responses to cancer
- (2015) Sebastian Kreiter et al. NATURE
- In vivo characterization of the physicochemical properties of polymer-linked TLR agonists that enhance vaccine immunogenicity
- (2015) Geoffrey M Lynn et al. NATURE BIOTECHNOLOGY
- Neoantigens in cancer immunotherapy
- (2015) T. N. Schumacher et al. SCIENCE
- Engineering New Approaches to Cancer Vaccines
- (2015) N. K. Mehta et al. Cancer Immunology Research
- TLR Signals Induce Phagosomal MHC-I Delivery from the Endosomal Recycling Compartment to Allow Cross-Presentation
- (2014) Priyanka Nair-Gupta et al. CELL
- Predicting immunogenic tumour mutations by combining mass spectrometry and exome sequencing
- (2014) Mahesh Yadav et al. NATURE
- Structure-based programming of lymph-node targeting in molecular vaccines
- (2014) Haipeng Liu et al. NATURE
- Genetic Basis for Clinical Response to CTLA-4 Blockade in Melanoma
- (2014) Alexandra Snyder et al. NEW ENGLAND JOURNAL OF MEDICINE
- Cancer Immunotherapy Based on Mutation-Specific CD4+ T Cells in a Patient with Epithelial Cancer
- (2014) E. Tran et al. SCIENCE
- Adjuvant-carrying synthetic vaccine particles augment the immune response to encapsulated antigen and exhibit strong local immune activation without inducing systemic cytokine release
- (2014) Petr O. Ilyinskii et al. VACCINE
- Efficient Induction of Antitumor Immunity by Synthetic Toll-like Receptor Ligand-Peptide Conjugates
- (2014) G. G. Zom et al. Cancer Immunology Research
- An update on safety and immunogenicity of vaccines containing emulsion-based adjuvants
- (2013) Christopher B Fox et al. Expert Review of Vaccines
- The use of Toll-like receptor 7/8 agonists as vaccine adjuvants
- (2013) John P Vasilakos et al. Expert Review of Vaccines
- Comparative Analysis of the Magnitude, Quality, Phenotype, and Protective Capacity of Simian Immunodeficiency Virus Gag-Specific CD8+ T Cells following Human-, Simian-, and Chimpanzee-Derived Recombinant Adenoviral Vector Immunization
- (2013) K. M. Quinn et al. JOURNAL OF IMMUNOLOGY
- Persistent antigen at vaccination sites induces tumor-specific CD8+ T cell sequestration, dysfunction and deletion
- (2013) Yared Hailemichael et al. NATURE MEDICINE
- Dendritic cell activation and T cell priming with adjuvant- and antigen-loaded oxidation-sensitive polymersomes
- (2012) Evan A. Scott et al. BIOMATERIALS
- BiVax: a peptide/poly-IC subunit vaccine that mimics an acute infection elicits vast and effective anti-tumor CD8 T-cell responses
- (2012) Hyun-Il Cho et al. CANCER IMMUNOLOGY IMMUNOTHERAPY
- Immune epitope database analysis resource
- (2012) Y. Kim et al. NUCLEIC ACIDS RESEARCH
- SPICE: Exploration and analysis of post-cytometric complex multivariate datasets
- (2011) Mario Roederer et al. CYTOMETRY PART A
- Cu-free click cycloaddition reactions in chemical biology
- (2010) John C. Jewett et al. CHEMICAL SOCIETY REVIEWS
- Vaccine Adjuvants: Putting Innate Immunity to Work
- (2010) Robert L. Coffman et al. IMMUNITY
- Structure−Activity Relationships in Human Toll-Like Receptor 7-Active Imidazoquinoline Analogues
- (2010) Nikunj M. Shukla et al. JOURNAL OF MEDICINAL CHEMISTRY
- Amphiphilic peptides and their cross-disciplinary role as building blocks for nanoscience
- (2009) Silvia Cavalli et al. CHEMICAL SOCIETY REVIEWS
- Vaccination against HPV-16 Oncoproteins for Vulvar Intraepithelial Neoplasia
- (2009) Gemma G. Kenter et al. NEW ENGLAND JOURNAL OF MEDICINE
- Nanoparticles target distinct dendritic cell populations according to their size
- (2008) Vania Manolova et al. EUROPEAN JOURNAL OF IMMUNOLOGY
- Superior induction of anti-tumor CTL immunity by extended peptide vaccines involves prolonged, DC-focused antigen presentation
- (2008) Martijn S. Bijker et al. EUROPEAN JOURNAL OF IMMUNOLOGY
Publish scientific posters with Peeref
Peeref publishes scientific posters from all research disciplines. Our Diamond Open Access policy means free access to content and no publication fees for authors.
Learn MoreAsk a Question. Answer a Question.
Quickly pose questions to the entire community. Debate answers and get clarity on the most important issues facing researchers.
Get Started