Overview of recent advances in liposomal nanoparticle-based cancer immunotherapy

Tumor-Targeted Chemoimmunotherapy with Immune-Checkpoint Blockade for Enhanced Anti-Melanoma Efficacy

(2019) Man Li et al.   AAPS Journal

Tumor Microenvironmental pH and Enzyme Dual Responsive Polymer-Liposomes for Synergistic Treatment of Cancer Immuno-Chemotherapy

(2019) Ya Liu et al.   BIOMACROMOLECULES

STAT3 inhibition specifically in human monocytes and macrophages by CD163-targeted corosolic acid-containing liposomes

(2019) Morten Nørgaard Andersen et al.   CANCER IMMUNOLOGY IMMUNOTHERAPY

A new immune-nanoplatform for promoting adaptive antitumor immune response

(2019) María Merino et al.   Nanomedicine-Nanotechnology Biology and Medicine

Tumor Microenvironment-Activatable Prodrug Vesicles for Nanoenabled Cancer Chemoimmunotherapy Combining Immunogenic Cell Death Induction and CD47 Blockade

(2019) Fangyuan Zhou et al.   ADVANCED MATERIALS

Natural killer cell membrane infused biomimetic liposomes for targeted tumor therapy

(2018) Arunkumar Pitchaimani et al.   BIOMATERIALS

Liposomal nanohybrid cerasomes targeted to PD-L1 enable dual-modality imaging and improve antitumor treatments

(2018) Yang Du et al.   CANCER LETTERS

Therapeutic Targeting of Tumor-Associated Macrophages in Pancreatic Neuroendocrine Tumors

(2018) Sebastian Krug et al.   INTERNATIONAL JOURNAL OF CANCER

Reversal of indoleamine 2,3-dioxygenase–mediated cancer immune suppression by systemic kynurenine depletion with a therapeutic enzyme

(2018) Todd A Triplett et al.   NATURE BIOTECHNOLOGY

Nanoparticle anchoring targets immune agonists to tumors enabling anti-cancer immunity without systemic toxicity

(2018) Yuan Zhang et al.   Nature Communications

Induction of enhanced immunogenic cell death through ultrasound-controlled release of doxorubicin by liposome-microbubble complexes

(2018) Feng-Ying Huang et al.   OncoImmunology

Binary Cooperative Prodrug Nanoparticles Improve Immunotherapy by Synergistically Modulating Immune Tumor Microenvironment

(2018) Bing Feng et al.   ADVANCED MATERIALS

Nanotechnology-mediated immunochemotherapy combined with docetaxel and PD-L1 antibody increase therapeutic effects and decrease systemic toxicity

(2018) Zili Gu et al.   JOURNAL OF CONTROLLED RELEASE

Personalized Tumor RNA Loaded Lipid-Nanoparticles Prime the Systemic and Intratumoral Milieu for Response to Cancer Immunotherapy

(2018) Elias J. Sayour et al.   NANO LETTERS

Self-Supplied Tumor Oxygenation through Separated Liposomal Delivery of H2O2 and Catalase for Enhanced Radio-Immunotherapy of Cancer

(2018) Xuejiao Song et al.   NANO LETTERS

EGFR-targeted liposomal nanohybrid cerasomes: theranostic function and immune checkpoint inhibition in a mouse model of colorectal cancer

(2018) Yuan Li et al.   Nanoscale

Breast Cancer Chemo-immunotherapy through Liposomal Delivery of an Immunogenic Cell Death Stimulus Plus Interference in the IDO-1 Pathway

(2018) Jianqin Lu et al.   ACS Nano

RNA-Based Immunostimulatory Liposomal Spherical Nucleic Acids as Potent TLR7/8 Modulators

(2018) Chenxia Guan et al.   Small

Strong adhesion by regulatory T cells induces dendritic cell cytoskeletal polarization and contact-dependent lethargy

(2017) Jiahuan Chen et al.   JOURNAL OF EXPERIMENTAL MEDICINE

De-novo and acquired resistance to immune checkpoint targeting

(2017) Nicholas L Syn et al.   LANCET ONCOLOGY

Elimination of tumor by CD47/PD-L1 dual-targeting fusion protein that engages innate and adaptive immune responses

(2017) Boning Liu et al.   mAbs

Phosphatidylserine Sensing by TAM Receptors Regulates AKT-Dependent Chemoresistance and PD-L1 Expression

(2017) Canan Kasikara et al.   MOLECULAR CANCER RESEARCH

Combination Cancer Therapy Using Chimeric Antigen Receptor-Engineered Natural Killer Cells as Drug Carriers

(2017) Elizabeth L. Siegler et al.   MOLECULAR THERAPY

Immunogenic Cell Death Amplified by Co-localized Adjuvant Delivery for Cancer Immunotherapy

(2017) Yuchen Fan et al.   NANO LETTERS

Reprogramming Tumor-Associated Macrophages To Reverse EGFRT790M Resistance by Dual-Targeting Codelivery of Gefitinib/Vorinostat

(2017) Huige Peng et al.   NANO LETTERS

Improved tumor accumulation and therapeutic efficacy of CTLA-4-blocking antibody using liposome-encapsulated antibody: In vitro and in vivo studies

(2017) Amin Reza Nikpoor et al.   Nanomedicine-Nanotechnology Biology and Medicine

Tumour-associated macrophages as treatment targets in oncology

(2017) Alberto Mantovani et al.   Nature Reviews Clinical Oncology

Aberrant control of NF-κB in cancer permits transcriptional and phenotypic plasticity, to curtail dependence on host tissue: molecular mode

(2017) A. Vlahopoulos Spiros   Cancer Biology & Medicine

Intracellularly Acid-Switchable Multifunctional Micelles for Combinational Photo/Chemotherapy of the Drug-Resistant Tumor

(2016) Tingting Wang et al.   ACS Nano

Super natural killer cells that target metastases in the tumor draining lymph nodes

(2016) Siddarth Chandrasekaran et al.   BIOMATERIALS

Exploiting in situ antigen generation and immune modulation to enhance chemotherapy response in advanced melanoma: A combination nanomedicine approach

(2016) Yao Lu et al.   CANCER LETTERS

Pharmacological macrophage inhibition decreases metastasis formation in a genetic model of pancreatic cancer

(2016) Heidi Griesmann et al.   GUT

Synthetic long peptide-based vaccine formulations for induction of cell mediated immunity: A comparative study of cationic liposomes and PLGA nanoparticles

(2016) Eleni Maria Varypataki et al.   JOURNAL OF CONTROLLED RELEASE

Acid-Activatable Versatile Micelleplexes for PD-L1 Blockade-Enhanced Cancer Photodynamic Immunotherapy

(2016) Dangge Wang et al.   NANO LETTERS

Drugs acting on homeostasis: challenging cancer cell adaptation

(2015) Maria Moschovi et al.   Expert Review of Anticancer Therapy

Multicomponent mannose-containing liposomes efficiently deliver RNA in murine immature dendritic cells and provide productive anti-tumour response in murine melanoma model

(2015) Oleg V. Markov et al.   JOURNAL OF CONTROLLED RELEASE

Liposomes loaded with a STING pathway ligand, cyclic di-GMP, enhance cancer immunotherapy against metastatic melanoma

(2015) Takashi Nakamura et al.   JOURNAL OF CONTROLLED RELEASE

Cationic Liposomes Loaded with a Synthetic Long Peptide and Poly(I:C): a Defined Adjuvanted Vaccine for Induction of Antigen-Specific T Cell Cytotoxicity

(2014) Eleni Maria Varypataki et al.   AAPS Journal

Nanoparticle-Delivered Transforming Growth Factor-β siRNA Enhances Vaccination against Advanced Melanoma by Modifying Tumor Microenvironment

(2014) Zhenghong Xu et al.   ACS Nano

The activation of the adaptive immune system: Cross-talk between antigen-presenting cells, T cells and B cells

(2014) Joke M.M. den Haan et al.   IMMUNOLOGY LETTERS

Structure-based programming of lymph-node targeting in molecular vaccines

(2014) Haipeng Liu et al.   NATURE

Induction of CD8+ T-cell responses against subunit antigens by the novel cationic liposomal CAF09 adjuvant

(2014) Karen Smith Korsholm et al.   VACCINE

Tumor metastasis: moving new biological insights into the clinic

(2013) Liling Wan et al.   NATURE MEDICINE

Immunogenic Cell Death in Cancer Therapy

(2012) Guido Kroemer et al.   Annual Review of Immunology

Innate or Adaptive Immunity? The Example of Natural Killer Cells

(2011) E. Vivier et al.   SCIENCE