Potential physio-pathological effects of branched fatty acid esters of hydroxy fatty acids

Effect of 9 - PAHSA on cognitive dysfunction in diabetic mice and its possible mechanism

(2020) Xiao-Hong Wen et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Long-term high intake of 9-PAHPA or 9-OAHPA increases basal metabolism and insulin sensitivity but disrupts liver homeostasis in healthy mice

(2020) Melha Benlebna et al.   JOURNAL OF NUTRITIONAL BIOCHEMISTRY

Interventional effects of the direct application of “Sanse powder” on knee osteoarthritis in rats as determined from lipidomics via UPLC-Q-Exactive Orbitrap MS

(2020) Peng Wu et al.   Chinese Medicine

Sensitive analysis of fatty acid esters of hydroxy fatty acids in biological lipid extracts by shotgun lipidomics after one-step derivatization

(2020) Changfeng Hu et al.   ANALYTICA CHIMICA ACTA

FAHFA footprint in the visceral fat of mice across their lifespan

(2020) Quan-Fei Zhu et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS

Metabolic Inflammation and Insulin Resistance in Obesity

(2020) Huaizhu Wu et al.   CIRCULATION RESEARCH

AIG1 and ADTRP are endogenous hydrolases of fatty acid esters of hydroxy fatty acids (FAHFAs) in mice

(2020) Meric Erikci Ertunc et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Triacylglycerol‐Rich Oils of Marine Origin are Optimal Nutrients for Induction of Polyunsaturated Docosahexaenoic Acid Ester of Hydroxy Linoleic Acid (13‐DHAHLA) with Anti‐Inflammatory Properties in Mice

(2020) Veronika Paluchova et al.   MOLECULAR NUTRITION & FOOD RESEARCH

Identification of short chain fatty acid esters of hydroxy fatty acids (SFAHFAs) in murine model by nontargeted analysis using ultra‐high‐performance liquid chromatography/linear trap quadrupole‐Orbitrap mass spectrometry

(2020) Siddabasave Gowda B. Gowda et al.   RAPID COMMUNICATIONS IN MASS SPECTROMETRY

Comparison of two anti-diabetic monoestolides regarding effects on intact murine liver tissue

(2020) David Rychtrmoc et al.   ARCHIVES OF PHYSIOLOGY AND BIOCHEMISTRY

Discovery of Eicosapentaenoic Acid Esters of Hydroxy Fatty Acids as Potent Nrf2 Activators

(2020) Siddabasave Gowda B. Gowda et al.   Antioxidants

Analytical Methods for the Determination of Fatty Acid Esters of Hydroxy Fatty Acids (FAHFAs) in Biological Samples, Plants and Foods

(2020) Maroula G. Kokotou   Biomolecules

Long-term intake of 9-PAHPA or 9-OAHPA modulates favorably the basal metabolism and exerts an insulin sensitizing effect in obesogenic diet-fed mice

(2020) Melha Benlebna et al.   EUROPEAN JOURNAL OF NUTRITION

Chemical Labeling Assisted Detection and Identification of Short Chain Fatty Acid Esters of Hydroxy Fatty Acid in Rat Colon and Cecum Contents

(2020) Siddabasave Gowda B. Gowda et al.   Metabolites

FAHFAs Regulate the Proliferation of C2C12 Myoblasts and Induce a Shift toward a More Oxidative Phenotype in Mouse Skeletal Muscle

(2020) Melha Benlebna et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Moose and Caribou as Novel Sources of Functional Lipids: Fatty Acid Esters of Hydroxy Fatty Acids, Diglycerides and Monoacetyldiglycerides

(2019) Thu Pham et al.   MOLECULES

High Glucose Concentration Impairs 5-PAHSA Activity by Inhibiting AMP-Activated Protein Kinase Activation and Promoting Nuclear Factor-Kappa-B-Mediated Inflammation

(2019) Yan-Mei Wang et al.   Frontiers in Pharmacology

Asymmetric Synthesis of Saturated Hydroxy Fatty Acids and Fatty Acid Esters of Hydroxy Fatty Acids

(2019) Olga G. Mountanea et al.   EUROPEAN JOURNAL OF ORGANIC CHEMISTRY

Synthesis of chemically edited derivatives of the endogenous regulator of inflammation 9-PAHSA

(2019) Huijing Wang et al.   JOURNAL OF ANTIBIOTICS

Discovery of FAHFA-Containing Triacylglycerols and Their Metabolic Regulation

(2019) Dan Tan et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Analysis of Fatty Acid Esters of Hydroxyl Fatty Acid in Selected Plant Food

(2019) Ana-Marija Liberati-Čizmek et al.   PLANT FOODS FOR HUMAN NUTRITION

Dynamic repression by BCL6 controls the genome-wide liver response to fasting and steatosis

(2019) Meredith A Sommars et al.   eLife

Sequestration of 9-Hydroxystearic Acid in FAHFA (Fatty Acid Esters of Hydroxy Fatty Acids) as a Protective Mechanism for Colon Carcinoma Cells to Avoid Apoptotic Cell Death

(2019) Juan P. Rodríguez et al.   Cancers

Linoleic acid esters of hydroxy linoleic acids are anti-inflammatory lipids found in plants and mammals

(2019) Matthew J. Kolar et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Enantioselective Organocatalysis-Based Synthesis of 3-Hydroxy Fatty Acids and Fatty γ-Lactones

(2019) Asimina Bourboula et al.   MOLECULES

PAHSAs attenuate immune responses and promote β cell survival in autoimmune diabetic mice

(2019) Ismail Syed et al.   JOURNAL OF CLINICAL INVESTIGATION

PAHSAs enhance hepatic and systemic insulin sensitivity through direct and indirect mechanisms

(2019) Peng Zhou et al.   JOURNAL OF CLINICAL INVESTIGATION

Stereochemistry of Linoleic Acid Esters of Hydroxy Linoleic Acids

(2019) Huijing Wang et al.   ORGANIC LETTERS

Free Fatty Acid Receptors in Health and Disease

(2019) Ikuo Kimura et al.   PHYSIOLOGICAL REVIEWS

Exercise training induces insulin-sensitizing PAHSAs in adipose tissue of elderly women

(2019) Marie Brezinova et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS

Lipokine 5-PAHSA Is Regulated by Adipose Triglyceride Lipase and Primes Adipocytes for De Novo Lipogenesis in Mice

(2019) Veronika Paluchova et al.   DIABETES

Synthesis of both enantiomers of the docosahexaenoic acid ester of 13-hydroxyoctadecadienoic acid (13-DHAHLA)

(2019) Anders Vik et al.   TETRAHEDRON LETTERS

The effect of ω-3 polyunsaturated fatty acids on the liver lipidome, proteome and bile acid profile: parenteral versus enteral administration

(2019) Kamila Bechynska et al.   Scientific Reports

Levels of palmitic acid ester of hydroxystearic acid (PAHSA) are reduced in the breast milk of obese mothers

(2018) Marie Brezinova et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS

Palmitic Acid Hydroxystearic Acids Activate GPR40, Which Is Involved in Their Beneficial Effects on Glucose Homeostasis

(2018) Ismail Syed et al.   Cell Metabolism

Acute and Repeated Treatment with 5-PAHSA or 9-PAHSA Isomers Does Not Improve Glucose Control in Mice

(2018) Elsa Pflimlin et al.   Cell Metabolism

Branched Fatty Acyl Esters of Hydroxyl Fatty Acids (FAHFAs), Appealing Beneficial Endogenous Fat against Obesity and Type-2 Diabetes

(2018) Laurence Balas et al.   CHEMISTRY-A EUROPEAN JOURNAL

Nrf2-Mediated Antioxidant Defense and Peroxiredoxin 6 Are Linked to Biosynthesis of Palmitic Acid Ester of 9-Hydroxystearic Acid

(2018) Ondrej Kuda et al.   DIABETES

Nrf2 at the heart of oxidative stress and cardiac protection

(2018) Qin M. Chen et al.   PHYSIOLOGICAL GENOMICS

Comprehensive Screening and Identification of Fatty Acid Esters of Hydroxy Fatty Acids in Plant Tissues by Chemical Isotope Labeling-Assisted Liquid Chromatography–Mass Spectrometry

(2018) Quan-Fei Zhu et al.   ANALYTICAL CHEMISTRY

On the Complexity of PAHSA Research

(2018) Ondrej Kuda   Cell Metabolism

Methodological Issues in Studying PAHSA Biology: Masking PAHSA Effects

(2018) Ismail Syed et al.   Cell Metabolism

Microfluidic-enabled quantitative measurements of insulin release dynamics from single islets of Langerhans in response to 5-palmitic acid hydroxy stearic acid

(2018) Basel Bandak et al.   LAB ON A CHIP

Adipose tissue dysfunction is associated with low levels of the novel Palmitic Acid Hydroxystearic Acids

(2018) Ann Hammarstedt et al.   Scientific Reports

9-PAHSA promotes browning of white fat via activating G-protein-coupled receptor 120 and inhibiting lipopolysaccharide / NF-kappa B pathway

(2018) Yan-Mei Wang et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Loss of Transcriptional Repression by BCL6 Confers Insulin Sensitivity in the Setting of Obesity

(2018) Madhavi D. Senagolage et al.   Cell Reports

Subterminal hydroxyeicosatetraenoic acids: Crucial lipid mediators in normal physiology and disease states

(2018) Sherif M. Shoieb et al.   CHEMICO-BIOLOGICAL INTERACTIONS

Highly sensitive determination of fatty acid esters of hydroxyl fatty acids by liquid chromatography-mass spectrometry

(2017) Quan-Fei Zhu et al.   JOURNAL OF CHROMATOGRAPHY B-ANALYTICAL TECHNOLOGIES IN THE BIOMEDICAL AND LIFE SCIENCES

Stereochemistry of Endogenous Palmitic Acid Ester of 9-Hydroxystearic Acid and Relevance of Absolute Configuration to Regulation

(2017) Andrew T. Nelson et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

FFA4 (GPR120) as a fatty acid sensor involved in appetite control, insulin sensitivity and inflammation regulation

(2017) Dong-Soon Im   MOLECULAR ASPECTS OF MEDICINE

Succinct synthesis of saturated hydroxy fatty acids and in vitro evaluation of all hydroxylauric acids on FFA1, FFA4 and GPR84

(2017) Mads Holmgaard Kaspersen et al.   MedChemComm

Absence of Carbohydrate Response Element Binding Protein in Adipocytes Causes Systemic Insulin Resistance and Impairs Glucose Transport

(2017) Archana Vijayakumar et al.   Cell Reports

Branched Fatty Acid Esters of Hydroxy Fatty Acids Are Preferred Substrates of the MODY8 Protein Carboxyl Ester Lipase

(2016) Matthew J. Kolar et al.   BIOCHEMISTRY

Docosahexaenoic Acid–Derived Fatty Acid Esters of Hydroxy Fatty Acids (FAHFAs) With Anti-inflammatory Properties

(2016) Ondrej Kuda et al.   DIABETES

GLUT4 Expression in Adipocytes Regulates De Novo Lipogenesis and Levels of a Novel Class of Lipids With Antidiabetic and Anti-inflammatory Effects

(2016) Pedro M. Moraes-Vieira et al.   DIABETES

Branched Fatty Acid Esters of Hydroxy Fatty Acids (FAHFAs) Protect against Colitis by Regulating Gut Innate and Adaptive Immune Responses

(2016) Jennifer Lee et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Adipose tissue regulates insulin sensitivity: role of adipogenesis,de novolipogenesis and novel lipids

(2016) U. Smith et al.   JOURNAL OF INTERNAL MEDICINE

AIG1 and ADTRP are atypical integral membrane hydrolases that degrade bioactive FAHFAs

(2016) William H Parsons et al.   Nature Chemical Biology

Structural verification via convergent total synthesis of dipeptide–lipids isolated from Porphyromonas gingivalis

(2016) Christopher Dietz et al.   TETRAHEDRON

Triacylglycerol Estolides, a New Class of Mammalian Lipids, in the Paracloacal Gland of the Brushtail Possum (Trichosurus vulpecula)

(2015) Stuart McLean et al.   LIPIDS

Discovery of a Class of Endogenous Mammalian Lipids with Anti-Diabetic and Anti-inflammatory Effects

(2014) Mark M. Yore et al.   CELL

Chemistry of phospholipid oxidation

(2012) Ana Reis et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES

FAT SIGNALS - Lipases and Lipolysis in Lipid Metabolism and Signaling

(2012) Rudolf Zechner et al.   Cell Metabolism

Adipose tissue dysregulation and reduced insulin sensitivity in non-obese individuals with enlarged abdominal adipose cells

(2012) Ann Hammarstedt et al.   Diabetology & Metabolic Syndrome

Thematic Review Series: Glycerolipids.DGAT enzymes and triacylglycerol biosynthesis

(2008) Chi-Liang Eric Yen et al.   JOURNAL OF LIPID RESEARCH

The Identification of Mono-, Di-, Tri-, and Tetragalactosyl-diacylglycerols and their Natural Estolides in Oat Kernels

(2008) Robert A. Moreau et al.   LIPIDS

Risk for colorectal cancer in ulcerative colitis: Changes, causes and management strategies

(2008) Peter Laszlo Lakatos et al.   WORLD JOURNAL OF GASTROENTEROLOGY