Asymmetric Synthesis of Saturated Hydroxy Fatty Acids and Fatty Acid Esters of Hydroxy Fatty Acids

Faster Protocol for Endogenous Fatty Acid Esters of Hydroxy Fatty Acid (FAHFA) Measurements

(2018) Matthew J. Kolar et al.   ANALYTICAL CHEMISTRY

Palmitic Acid Hydroxystearic Acids Activate GPR40, Which Is Involved in Their Beneficial Effects on Glucose Homeostasis

(2018) Ismail Syed et al.   Cell Metabolism

Acute and Repeated Treatment with 5-PAHSA or 9-PAHSA Isomers Does Not Improve Glucose Control in Mice

(2018) Elsa Pflimlin et al.   Cell Metabolism

Comprehensive Screening and Identification of Fatty Acid Esters of Hydroxy Fatty Acids in Plant Tissues by Chemical Isotope Labeling-Assisted Liquid Chromatography–Mass Spectrometry

(2018) Quan-Fei Zhu et al.   ANALYTICAL CHEMISTRY

An Efficient Synthesis of Chiral Non‐Racemic Hydroxyalkanoic Acids by Olefin Cross‐Metathesis Reactions

(2018) Fioretta Asaro et al.   ChemistrySelect

Stereochemistry of Endogenous Palmitic Acid Ester of 9-Hydroxystearic Acid and Relevance of Absolute Configuration to Regulation

(2017) Andrew T. Nelson et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

First deuterated drug approved

(2017) Charles Schmidt   NATURE BIOTECHNOLOGY

Succinct synthesis of saturated hydroxy fatty acids and in vitro evaluation of all hydroxylauric acids on FFA1, FFA4 and GPR84

(2017) Mads Holmgaard Kaspersen et al.   MedChemComm

GLUT4 Expression in Adipocytes Regulates De Novo Lipogenesis and Levels of a Novel Class of Lipids With Antidiabetic and Anti-inflammatory Effects

(2016) Pedro M. Moraes-Vieira et al.   DIABETES

Branched Fatty Acid Esters of Hydroxy Fatty Acids (FAHFAs) Protect against Colitis by Regulating Gut Innate and Adaptive Immune Responses

(2016) Jennifer Lee et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

A LC-MS–based workflow for measurement of branched fatty acid esters of hydroxy fatty acids

(2016) Tejia Zhang et al.   Nature Protocols

Regiocontrolled syntheses of FAHFAs and LC-MS/MS differentiation of regioisomers

(2016) Laurence Balas et al.   ORGANIC & BIOMOLECULAR CHEMISTRY

Enantioselective Organocatalytic Synthesis of 2-Oxopiperazines from Aldehydes: Identification of the Elusive Epoxy Lactone Intermediate

(2016) Nikolaos Kaplaneris et al.   ORGANIC LETTERS

Roles of specific lipid species in the cell and their molecular mechanism

(2016) Tomohiro Kimura et al.   PROGRESS IN LIPID RESEARCH

Discovery of a Class of Endogenous Mammalian Lipids with Anti-Diabetic and Anti-inflammatory Effects

(2014) Mark M. Yore et al.   CELL

Total Synthesis of Nominal Gobienine A

(2013) Azusa Kondoh et al.   CHEMISTRY-A EUROPEAN JOURNAL

Lipidomics in drug discovery

(2013) Terhi Vihervaara et al.   DRUG DISCOVERY TODAY

Using Deuterium in Drug Discovery: Leaving the Label in the Drug

(2013) Thomas G. Gant   JOURNAL OF MEDICINAL CHEMISTRY

Investigation of the origin and synthetic application of the pseudodilution effect for Pd-catalyzed macrocyclisations in concentrated solutions with immobilized catalysts

(2013) Elisabeth Brehm et al.   ORGANIC & BIOMOLECULAR CHEMISTRY

Synthesis of optically active heterocyclic compounds via deracemization of 1,2-diol monotosylate derivatives bearing a long aliphatic chain by a combination of enzymatic hydrolysis with Mitsunobu inversion

(2013) Kazutsugu Matsumoto et al.   TETRAHEDRON-ASYMMETRY

Organocatalysis in synthesis and reactions of epoxides and aziridines

(2013) Ruchi Chawla et al.   RSC Advances

Emerging targets in lipid-based therapy

(2012) Stephanie C. Tucker et al.   BIOCHEMICAL PHARMACOLOGY

Enzymatic kinetic resolution of hydroxystearic acids: A combined experimental and molecular modelling investigation

(2012) Cynthia Ebert et al.   JOURNAL OF MOLECULAR CATALYSIS B-ENZYMATIC

Preparation of α-labeled aldehydes by base-catalyzed exchange reactions

(2010) Xavier Ariza et al.   JOURNAL OF LABELLED COMPOUNDS & RADIOPHARMACEUTICALS

Activity-Based Probes That Target Functional Subclasses of Phospholipases in Proteomes

(2010) Sarah E. Tully et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Enantioselective synthesis of (+)-patulolide C via proline-catalyzed sequential α-aminooxylation and Horner–Wadsworth–Emmons olefination

(2010) Gowravaram Sabitha et al.   TETRAHEDRON LETTERS

Enantioselective Linchpin Catalysis by SOMO Catalysis: An Approach to the Asymmetric α-Chlorination of Aldehydes and Terminal Epoxide Formation

(2009) Muriel Amatore et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

The advent and development of organocatalysis

(2008) David W. C. MacMillan   NATURE