PAHSAs attenuate immune responses and promote β cell survival in autoimmune diabetic mice
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Title
PAHSAs attenuate immune responses and promote β cell survival in autoimmune diabetic mice
Authors
Keywords
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Journal
JOURNAL OF CLINICAL INVESTIGATION
Volume 129, Issue 9, Pages 3717-3731
Publisher
American Society for Clinical Investigation
Online
2019-08-05
DOI
10.1172/jci122445
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- (2017) Andrew T. Nelson et al. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
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- (2017) Miriam Cnop et al. Molecular Metabolism
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- (2016) Matthew J. Kolar et al. BIOCHEMISTRY
- NSC23766, a Known Inhibitor of Tiam1-Rac1 Signaling Module, Prevents the Onset of Type 1 Diabetes in the NOD Mouse Model
- (2016) Rajakrishnan Veluthakal et al. CELLULAR PHYSIOLOGY AND BIOCHEMISTRY
- Docosahexaenoic Acid–Derived Fatty Acid Esters of Hydroxy Fatty Acids (FAHFAs) With Anti-inflammatory Properties
- (2016) Ondrej Kuda et al. DIABETES
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- (2016) Jennifer Lee et al. JOURNAL OF BIOLOGICAL CHEMISTRY
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- (2016) William H Parsons et al. Nature Chemical Biology
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- (2016) Flora Brozzi et al. UPSALA JOURNAL OF MEDICAL SCIENCES
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- (2015) Susan J. Burke et al. AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM
- Thinking bedside at the bench: the NOD mouse model of T1DM
- (2015) James C. Reed et al. Nature Reviews Endocrinology
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- (2015) Yan Ma et al. Journal of Cheminformatics
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- (2014) Mark M. Yore et al. CELL
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- (2014) H Peter Chase et al. PEDIATRIC DIABETES
- Epigenetic modulation of type-1 diabetes via a dual effect on pancreatic macrophages and β cells
- (2014) Wenxian Fu et al. eLife
- The role of reactive oxygen species and proinflammatory cytokines in type 1 diabetes pathogenesis
- (2013) Lindsey E. Padgett et al. Annals of the New York Academy of Sciences
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- (2012) Johnny Ludvigsson et al. NEW ENGLAND JOURNAL OF MEDICINE
- Omega-3 fatty acids and their lipid mediators: Towards an understanding of resolvin and protectin formation
- (2012) Karsten H. Weylandt et al. PROSTAGLANDINS & OTHER LIPID MEDIATORS
- How Does Type 1 Diabetes Develop?: The Notion of Homicide or -Cell Suicide Revisited
- (2011) M. A. Atkinson et al. DIABETES
- Anti-CD3 antibodies for type 1 diabetes: beyond expectations
- (2011) Jean-François Bach LANCET
- Prediction model for the incidence and prevalence of type 1 diabetes in childhood and adolescence: evidence for a cohort-dependent increase within the next two decades in Germany
- (2011) Stefan Ehehalt et al. PEDIATRIC DIABETES
- Erythrocyte membrane omega-3 fatty acid levels and omega-3 fatty acid intake are not associated with conversion to type 1 diabetes in children with islet autoimmunity: The Diabetes Autoimmunity Study in the Young (DAISY)
- (2011) Melissa R Miller et al. PEDIATRIC DIABETES
- Effects of pharmacological inhibition of NADPH oxidase or iNOS on pro-inflammatory cytokine, palmitic acid or H2O2-induced mouse islet or clonal pancreatic β-cell dysfunction
- (2010) Marta Michalska et al. BIOSCIENCE REPORTS
- Ductal Origin Hypothesis of Pancreatic Regeneration under Attack
- (2010) Jake A. Kushner et al. Cell Metabolism
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- (2010) A. Kowluru et al. DIABETES
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- (2010) David M. Maahs et al. ENDOCRINOLOGY AND METABOLISM CLINICS OF NORTH AMERICA
- Conversion of adult pancreatic α-cells to β-cells after extreme β-cell loss
- (2010) Fabrizio Thorel et al. NATURE
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- (2009) L. G. Grunnet et al. DIABETES
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- (2009) M. M. Rankin et al. DIABETES
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- Exendin-4 Modulates Diabetes Onset in Nonobese Diabetic Mice
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