Enantioselective Organocatalysis-Based Synthesis of 3-Hydroxy Fatty Acids and Fatty γ-Lactones

Asymmetric Synthesis of Saturated Hydroxy Fatty Acids and Fatty Acid Esters of Hydroxy Fatty Acids

(2019) Olga G. Mountanea et al.   EUROPEAN JOURNAL OF ORGANIC CHEMISTRY

Acute and Repeated Treatment with 5-PAHSA or 9-PAHSA Isomers Does Not Improve Glucose Control in Mice

(2018) Elsa Pflimlin et al.   Cell Metabolism

Stereochemistry of Endogenous Palmitic Acid Ester of 9-Hydroxystearic Acid and Relevance of Absolute Configuration to Regulation

(2017) Andrew T. Nelson et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

First deuterated drug approved

(2017) Charles Schmidt   NATURE BIOTECHNOLOGY

Succinct synthesis of saturated hydroxy fatty acids and in vitro evaluation of all hydroxylauric acids on FFA1, FFA4 and GPR84

(2017) Mads Holmgaard Kaspersen et al.   MedChemComm

Total Synthesis of Cryptocaryol A by Enantioselective Iridium-Catalyzed Alcohol C−H Allylation

(2016) Felix Perez et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Docosahexaenoic Acid–Derived Fatty Acid Esters of Hydroxy Fatty Acids (FAHFAs) With Anti-inflammatory Properties

(2016) Ondrej Kuda et al.   DIABETES

GLUT4 Expression in Adipocytes Regulates De Novo Lipogenesis and Levels of a Novel Class of Lipids With Antidiabetic and Anti-inflammatory Effects

(2016) Pedro M. Moraes-Vieira et al.   DIABETES

Profiling of 3-hydroxy fatty acids as environmental markers of endotoxin using liquid chromatography coupled to tandem mass spectrometry

(2016) Silvio Uhlig et al.   JOURNAL OF CHROMATOGRAPHY A

Total Synthesis of Tetraketide and Cryptorigidifoliol I via a Sequential Allylation Strategy

(2016) Birakishore Padhi et al.   JOURNAL OF NATURAL PRODUCTS

Total synthesis of fellutamides, lipopeptide proteasome inhibitors. More sustainable peptide bond formation

(2016) Michael C. Pirrung et al.   ORGANIC & BIOMOLECULAR CHEMISTRY

Enantioselective Organocatalytic Synthesis of 2-Oxopiperazines from Aldehydes: Identification of the Elusive Epoxy Lactone Intermediate

(2016) Nikolaos Kaplaneris et al.   ORGANIC LETTERS

An Easy Route to Enantiomerically Enriched 7- and 8-Hydroxy­stearic Acids by Olefin-Metathesis-Based Approach

(2016) Patrizia Nitti et al.   SYNLETT

Metabolite profiling, antioxidant and antibacterial activities of Brazilian propolis: Use of correlation and multivariate analyses to identify potential bioactive compounds

(2015) Mara L.F. Bittencourt et al.   FOOD RESEARCH INTERNATIONAL

Discovery of a Class of Endogenous Mammalian Lipids with Anti-Diabetic and Anti-inflammatory Effects

(2014) Mark M. Yore et al.   CELL

Free Fatty Acid (FFA) and Hydroxy Carboxylic Acid (HCA) Receptors

(2013) Stefan Offermanns   Annual Review of Pharmacology and Toxicology

Medium-chain Fatty Acid-sensing Receptor, GPR84, Is a Proinflammatory Receptor

(2013) Masakatsu Suzuki et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Using Deuterium in Drug Discovery: Leaving the Label in the Drug

(2013) Thomas G. Gant   JOURNAL OF MEDICINAL CHEMISTRY

Synthesis of optically active heterocyclic compounds via deracemization of 1,2-diol monotosylate derivatives bearing a long aliphatic chain by a combination of enzymatic hydrolysis with Mitsunobu inversion

(2013) Kazutsugu Matsumoto et al.   TETRAHEDRON-ASYMMETRY

Enantiodivergent Chemoenzymatic Synthesis of (S)- and (R)-(Z)-9-Dodecyl-4,5,8,9-tetrahydro-3H-oxonin-2-one as Analogues of Topsentolides

(2012) Isolde Wetzel et al.   LETTERS IN ORGANIC CHEMISTRY

Clinical applications of 3-hydroxy fatty acid analysis by gas chromatography–mass spectrometry

(2011) Patricia M. Jones et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS

Organocatalytic stereoselective synthesis of passifloricin A

(2011) Pradeep Kumar et al.   ORGANIC & BIOMOLECULAR CHEMISTRY

Preparation of α-labeled aldehydes by base-catalyzed exchange reactions

(2010) Xavier Ariza et al.   JOURNAL OF LABELLED COMPOUNDS & RADIOPHARMACEUTICALS

Enantioselective Linchpin Catalysis by SOMO Catalysis: An Approach to the Asymmetric α-Chlorination of Aldehydes and Terminal Epoxide Formation

(2009) Muriel Amatore et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Silver triflate-catalysed synthesis of γ-lactones from fatty acids

(2009) Lukas J. Gooßen et al.   GREEN CHEMISTRY

A simple and efficient enantioselective route to 2,6-disubstituted piperidines: synthesis of (2R,6S)-isosolenopsin A and (2S,6R)-isosolenopsin

(2009) R. Sateesh Chandra Kumar et al.   TETRAHEDRON-ASYMMETRY

The advent and development of organocatalysis

(2008) David W. C. MacMillan   NATURE