Long-term intake of 9-PAHPA or 9-OAHPA modulates favorably the basal metabolism and exerts an insulin sensitizing effect in obesogenic diet-fed mice

Global and regional estimates and projections of diabetes-related health expenditure: results from the International Diabetes Federation Diabetes Atlas, 9th edition

(2020) Rhys Williams et al.   DIABETES RESEARCH AND CLINICAL PRACTICE

Depot-specific UCP1 expression in human white adipose tissue and its association with obesity-related markers

(2020) Jisun Lim et al.   INTERNATIONAL JOURNAL OF OBESITY

Long-term high intake of 9-PAHPA or 9-OAHPA increases basal metabolism and insulin sensitivity but disrupts liver homeostasis in healthy mice

(2020) Melha Benlebna et al.   JOURNAL OF NUTRITIONAL BIOCHEMISTRY

High Glucose Concentration Impairs 5-PAHSA Activity by Inhibiting AMP-Activated Protein Kinase Activation and Promoting Nuclear Factor-Kappa-B-Mediated Inflammation

(2019) Yan-Mei Wang et al.   Frontiers in Pharmacology

Discovery of FAHFA-Containing Triacylglycerols and Their Metabolic Regulation

(2019) Dan Tan et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Linoleic acid esters of hydroxy linoleic acids are anti-inflammatory lipids found in plants and mammals

(2019) Matthew J. Kolar et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

WITHDRAWN: Global and regional diabetes prevalence estimates for 2019 and projections for 2030 and 2045: results from the International Diabetes Federation Diabetes Atlas, 9th edition

(2019) Pouya Saeedi et al.   DIABETES RESEARCH AND CLINICAL PRACTICE

PAHSAs enhance hepatic and systemic insulin sensitivity through direct and indirect mechanisms

(2019) Peng Zhou et al.   JOURNAL OF CLINICAL INVESTIGATION

Lipokine 5-PAHSA Is Regulated by Adipose Triglyceride Lipase and Primes Adipocytes for De Novo Lipogenesis in Mice

(2019) Veronika Paluchova et al.   DIABETES

Palmitic Acid Hydroxystearic Acids Activate GPR40, Which Is Involved in Their Beneficial Effects on Glucose Homeostasis

(2018) Ismail Syed et al.   Cell Metabolism

Acute and Repeated Treatment with 5-PAHSA or 9-PAHSA Isomers Does Not Improve Glucose Control in Mice

(2018) Elsa Pflimlin et al.   Cell Metabolism

Branched Fatty Acyl Esters of Hydroxyl Fatty Acids (FAHFAs), Appealing Beneficial Endogenous Fat against Obesity and Type-2 Diabetes

(2018) Laurence Balas et al.   CHEMISTRY-A EUROPEAN JOURNAL

Pathophysiology of Nonalcoholic Fatty Liver Disease/Nonalcoholic Steatohepatitis

(2018) Vignan Manne et al.   Clinics in Liver Disease

High dietary fat and sucrose result in an extensive and time-dependent deterioration in health of multiple physiological systems in mice

(2018) James G. Burchfield et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Raspberry promotes brown and beige adipocyte development in mice fed high-fat diet through activation of AMP-activated protein kinase (AMPK) α1

(2018) Tiande Zou et al.   JOURNAL OF NUTRITIONAL BIOCHEMISTRY

Role of Oxidative Stress in Pathophysiology of Nonalcoholic Fatty Liver Disease

(2018) Mario Masarone et al.   Oxidative Medicine and Cellular Longevity

On the Complexity of PAHSA Research

(2018) Ondrej Kuda   Cell Metabolism

Methodological Issues in Studying PAHSA Biology: Masking PAHSA Effects

(2018) Ismail Syed et al.   Cell Metabolism

Microfluidic-enabled quantitative measurements of insulin release dynamics from single islets of Langerhans in response to 5-palmitic acid hydroxy stearic acid

(2018) Basel Bandak et al.   LAB ON A CHIP

Pathogenesis of Nonalcoholic Steatohepatitis and Hormone-Based Therapeutic Approaches

(2018) Kook Hwan Kim et al.   Frontiers in Endocrinology

9-PAHSA promotes browning of white fat via activating G-protein-coupled receptor 120 and inhibiting lipopolysaccharide / NF-kappa B pathway

(2018) Yan-Mei Wang et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Simultaneous quantitative profiling of 20 isoprostanoids from omega-3 and omega-6 polyunsaturated fatty acids by LC–MS/MS in various biological samples

(2016) Aude Dupuy et al.   ANALYTICA CHIMICA ACTA

A mitochondrial-targeted ubiquinone modulates muscle lipid profile and improves mitochondrial respiration in obesogenic diet-fed rats

(2016) Charles Coudray et al.   BRITISH JOURNAL OF NUTRITION

Docosahexaenoic Acid–Derived Fatty Acid Esters of Hydroxy Fatty Acids (FAHFAs) With Anti-inflammatory Properties

(2016) Ondrej Kuda et al.   DIABETES

GLUT4 Expression in Adipocytes Regulates De Novo Lipogenesis and Levels of a Novel Class of Lipids With Antidiabetic and Anti-inflammatory Effects

(2016) Pedro M. Moraes-Vieira et al.   DIABETES

Increased Energy Expenditure,Ucp1Expression, and Resistance to Diet-induced Obesity in Mice Lacking Nuclear Factor-Erythroid-2-related Transcription Factor-2 (Nrf2)

(2016) Kevin Schneider et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Regiocontrolled syntheses of FAHFAs and LC-MS/MS differentiation of regioisomers

(2016) Laurence Balas et al.   ORGANIC & BIOMOLECULAR CHEMISTRY

Discovery of a Class of Endogenous Mammalian Lipids with Anti-Diabetic and Anti-inflammatory Effects

(2014) Mark M. Yore et al.   CELL

Global, regional, and national prevalence of overweight and obesity in children and adults during 1980–2013: a systematic analysis for the Global Burden of Disease Study 2013

(2014) Marie Ng et al.   LANCET

Diet-induced mouse model of fatty liver disease and nonalcoholic steatohepatitis reflecting clinical disease progression and methods of assessment

(2013) Jason R. Clapper et al.   AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY

Differential effects of high-carbohydrate and high-fat diets on hepatic lipogenesis in rats

(2013) Alessandra Ferramosca et al.   EUROPEAN JOURNAL OF NUTRITION

Quantifying hepatic steatosis - more than meets the eye

(2012) Adam P Levene et al.   HISTOPATHOLOGY

Inflammation and fibrogenesis in steatohepatitis

(2012) Hideki Fujii et al.   JOURNAL OF GASTROENTEROLOGY

Pan-PPAR agonist beneficial effects in overweight mice fed a high-fat high-sucrose diet

(2009) Caroline Fernandes-Santos et al.   NUTRITION

Oxidative stress in rats fed a high-fat high-sucrose diet and preventive effect of polyphenols: Involvement of mitochondrial and NAD(P)H oxidase systems

(2008) C. Feillet-Coudray et al.   FREE RADICAL BIOLOGY AND MEDICINE