Inhibition of p300 by Garcinol Protects against Cisplatin-Induced Acute Kidney Injury through Suppression of Oxidative Stress, Inflammation, and Tubular Cell Death in Mice

Increased p300/CBP expression in acute respiratory distress syndrome is associated with interleukin‐17 and prognosis

(2020) Yan Chen et al.   Clinical Respiratory Journal

Cardioprotective effects of garcinol following myocardial infarction in rats with isoproterenol-induced heart failure

(2020) Man Li et al.   AMB Express

Protective Effects of SPA0355, a Thiourea Analogue, Against Lipopolysaccharide-Induced Acute Kidney Injury in Mice

(2020) Jung-Yeon Kim et al.   Antioxidants

Protective Effects of Bee Venom against Endotoxemia-Related Acute Kidney Injury in Mice

(2020) Jung-Yeon Kim et al.   Biology-Basel

Epigenetic regulation in AKI and kidney repair: mechanisms and therapeutic implications

(2019) Chunyuan Guo et al.   Nature Reviews Nephrology

Inhibition of p300/CBP-Associated Factor Attenuates Renal Tubulointerstitial Fibrosis through Modulation of NF-kB and Nrf2

(2019) Sungjin Chung et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Garcinol Sensitizes NSCLC Cells to Standard Therapies by Regulating EMT-Modulating miRNAs

(2019) Mohd Farhan et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

The cleavage of gasdermin D by caspase-11 promotes tubular epithelial cell pyroptosis and urinary IL-18 excretion in acute kidney injury

(2019) Naijun Miao et al.   KIDNEY INTERNATIONAL

Garcinol Suppresses IL-1β-Induced Chondrocyte Inflammation and Osteoarthritis via Inhibition of the NF-κB Signaling Pathway

(2019) Yewei Jia et al.   INFLAMMATION

Recent Advances in Models, Mechanisms, Biomarkers, and Interventions in Cisplatin-Induced Acute Kidney Injury

(2019) Sara J. Holditch et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Supplementation of Saponins from Leaves of Panax quinquefolius Mitigates Cisplatin-Evoked Cardiotoxicity via Inhibiting Oxidative Stress-Associated Inflammation and Apoptosis in Mice

(2019) Jing-Jing Xing et al.   Antioxidants

Pharmacological Activation of Sirt1 Ameliorates Cisplatin-Induced Acute Kidney Injury by Suppressing Apoptosis, Oxidative Stress, and Inflammation in Mice

(2019) Jung-Yeon Kim et al.   Antioxidants

Protective Effects of Melatonin Against Aristolochic Acid-Induced Nephropathy in Mice

(2019) Jung-Yeon Kim et al.   Biomolecules

Loci-specific histone acetylation profiles associated with transcriptional coactivator p300 during early myoblast differentiation

(2018) Saadia Khilji et al.   Epigenetics

C-peptide prevents NF-κB from recruiting p300 and binding to the inos promoter in diabetic nephropathy

(2018) Yanning Li et al.   FASEB JOURNAL

Asiatic acid protects against cisplatin-induced acute kidney injury via anti-apoptosis and anti-inflammation

(2018) Chen Yang et al.   BIOMEDICINE & PHARMACOTHERAPY

Physical exercise contributes to cisplatin-induced nephrotoxicity protection with decreased CD4+ T cells activation

(2018) Mariana Yasue Saito Miyagi et al.   MOLECULAR IMMUNOLOGY

Pharmacological Inhibition of Caspase-1 Ameliorates Cisplatin-Induced Nephrotoxicity through Suppression of Apoptosis, Oxidative Stress, and Inflammation in Mice

(2018) Jung-Yeon Kim et al.   MEDIATORS OF INFLAMMATION

NADPH oxidase 4 promotes cisplatin-induced acute kidney injury via ROS-mediated programmed cell death and inflammation

(2017) Xiao-Ming Meng et al.   LABORATORY INVESTIGATION

Protective effects of Garcinol against neuropathic pain – Evidence from in vivo and in vitro studies

(2017) Yi-wei Wang et al.   NEUROSCIENCE LETTERS

The peroxisome proliferator-activated receptor γ agonist pioglitazone prevents NF-κB activation in cisplatin nephrotoxicity through the reduction of p65 acetylation via the AMPK-SIRT1/p300 pathway

(2016) Jiong Zhang et al.   BIOCHEMICAL PHARMACOLOGY

The inflammatory cytokine TWEAK decreases PGC-1α expression and mitochondrial function in acute kidney injury

(2016) Olga Ruiz-Andres et al.   KIDNEY INTERNATIONAL

HAT inhibitor, garcinol, exacerbates lipopolysaccharide-induced inflammation in vitro and in vivo

(2016) BIN WANG et al.   Molecular Medicine Reports

Garcinol Upregulates GABAA and GAD65 Expression, Modulates BDNF-TrkB Pathway to Reduce Seizures in Pentylenetetrazole (PTZ)-Induced Epilepsy

(2016) Fang Hao et al.   MEDICAL SCIENCE MONITOR

Histone acetyltransferase PCAF regulates inflammatory molecules in the development of renal injury

(2015) Jin Huang et al.   Epigenetics

Garcinol sensitizes human head and neck carcinoma to cisplatin in a xenograft mouse model despite downregulation of proliferative biomarkers

(2015) Feng Li et al.   Oncotarget

Protective effects of garcinol in mice with lipopolysaccharide/D-galactosamine-induced apoptotic liver injury

(2014) Yuping Jing et al.   INTERNATIONAL IMMUNOPHARMACOLOGY

Genome-wide and single-cell analyses reveal a context dependent relationship between CBP recruitment and gene expression

(2014) Lawryn H. Kasper et al.   NUCLEIC ACIDS RESEARCH

SIRT1 overexpression decreases cisplatin-induced acetylation of NF-κB p65 subunit and cytotoxicity in renal proximal tubule cells

(2012) Yu Jin Jung et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Chemoprevention of 7,12-dimethylbenz[a]anthracene (DMBA)-induced Hamster Cheek Pouch Carcinogenesis by a 5-Lipoxygenase Inhibitor, Garcinol

(2012) Xin Chen et al.   NUTRITION AND CANCER-AN INTERNATIONAL JOURNAL

An integrative view of the pathophysiological events leading to cisplatin nephrotoxicity

(2011) Penélope D. Sánchez-González et al.   CRITICAL REVIEWS IN TOXICOLOGY

Distinct roles of GCN5/PCAF-mediated H3K9ac and CBP/p300-mediated H3K18/27ac in nuclear receptor transactivation

(2010) Qihuang Jin et al.   EMBO JOURNAL

Kidney-specific Overexpression of Sirt1 Protects against Acute Kidney Injury by Retaining Peroxisome Function

(2010) Kazuhiro Hasegawa et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Salt-inducible kinase 2 links transcriptional coactivator p300 phosphorylation to the prevention of ChREBP-dependent hepatic steatosis in mice

(2010) Julien Bricambert et al.   JOURNAL OF CLINICAL INVESTIGATION

Amelioration of cisplatin nephrotoxicity by genetic or pharmacologic blockade of prostaglandin synthesis

(2010) Zhanjun Jia et al.   KIDNEY INTERNATIONAL

Curcumin prevents diabetes-associated abnormalities in the kidneys by inhibiting p300 and nuclear factor-κB

(2009) Jane Chiu et al.   NUTRITION

Effects of garcinol and guttiferone K isolated fromGarcinia cambogiaon oxidative/nitrative modifications in blood platelets and plasma

(2009) Joanna Kolodziejczyk et al.   PLATELETS

Interleukin-6 deficiency accelerates cisplatin-induced acute renal failure but not systemic injury

(2009) S. Mitazaki et al.   TOXICOLOGY

Epigenetic Regulation of BMP7 in the Regenerative Response to Ischemia

(2008) T. Marumo et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Cisplatin nephrotoxicity: Mechanisms and renoprotective strategies

(2008) N. Pabla et al.   KIDNEY INTERNATIONAL

Selective iNOS inhibition reduces renal damage induced by cisplatin

(2007) Yolanda I. Chirino et al.   TOXICOLOGY LETTERS