Recent Advances in Models, Mechanisms, Biomarkers, and Interventions in Cisplatin-Induced Acute Kidney Injury

An Early Decrease in Release of Aquaporin-2 in Urinary Extracellular Vesicles After Cisplatin Treatment in Rats

(2019) Hiroko Sonoda et al.   Cells

Epigenetic Regulation in Kidney Toxicity: Insights From Cisplatin Nephrotoxicity

(2019) Xiaohong Xiang et al.   SEMINARS IN NEPHROLOGY

Anti-inflammatory role of tempol (4-hydroxy-2,2,6,6-tetramethylpiperidin-1-oxyl) in nephroprotection

(2019) MA Afjal et al.   HUMAN & EXPERIMENTAL TOXICOLOGY

Mesenchymal Stem Cells: a Promising Therapeutic Tool for Acute Kidney Injury

(2019) Rehab E. Selim et al.   APPLIED BIOCHEMISTRY AND BIOTECHNOLOGY

Renoprotective effect of scutellarin on cisplatin-induced renal injury in mice: Impact on inflammation, apoptosis, and autophagy

(2019) Chao-Yue Sun et al.   BIOMEDICINE & PHARMACOTHERAPY

Regulated necrosis and failed repair in cisplatin-induced chronic kidney disease

(2019) Sarah I. Landau et al.   KIDNEY INTERNATIONAL

Renalase attenuates mitochondrial fission in cisplatin-induced acute kidney injury via modulating sirtuin-3

(2019) Zhimin Huang et al.   LIFE SCIENCES

Endoplasmic reticulum stress in ischemic and nephrotoxic acute kidney injury

(2018) Mingjuan Yan et al.   ANNALS OF MEDICINE

Estrogen-related receptor α is essential for maintaining mitochondrial integrity in cisplatin-induced acute kidney injury

(2018) Keigo Tsushida et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Blockade of histone deacetylase 6 protects against cisplatin-induced acute kidney injury

(2018) Jinhua Tang et al.   CLINICAL SCIENCE

TLR2 and TLR4 Play Opposite Role in Autophagy associated with Cisplatin-Induced Acute Kidney Injury

(2018) Magaiver Andrade-Silva et al.   CLINICAL SCIENCE

Astilbin ameliorates cisplatin-induced nephrotoxicity through reducing oxidative stress and inflammation

(2018) Si-wei Wang et al.   FOOD AND CHEMICAL TOXICOLOGY

Morin hydrate ameliorates cisplatin-induced ER stress, inflammation and autophagy in HEK-293 cells and mice kidney via PARP-1 regulation

(2018) Mahendra Pal Singh et al.   INTERNATIONAL IMMUNOPHARMACOLOGY

Renoprotective effect of the isoflavonoid biochanin A against cisplatin induced acute kidney injury in mice: Effect on inflammatory burden and p53 apoptosis

(2018) Faiha A. Suliman et al.   INTERNATIONAL IMMUNOPHARMACOLOGY

Improvement of Cisplatin-induced renal dysfunction by Schisandra chinensis stems via anti-inflammation and anti-apoptosis effects

(2018) Yan-Zi Li et al.   JOURNAL OF ETHNOPHARMACOLOGY

Overexpressed SIRT6 attenuates cisplatin-induced acute kidney injury by inhibiting ERK1/2 signaling

(2018) Zhongchi Li et al.   KIDNEY INTERNATIONAL

Restoration of E-cadherin by PPBICA protects against cisplatin-induced acute kidney injury by attenuating inflammation and programmed cell death

(2018) Li Gao et al.   LABORATORY INVESTIGATION

Cisplatin nephrotoxicity as a model of chronic kidney disease

(2018) Mingjun Shi et al.   LABORATORY INVESTIGATION

Comparison of acute kidney injury of different etiology reveals in-common mechanisms of tissue damage

(2018) Michael Hultström et al.   PHYSIOLOGICAL GENOMICS

Cisplatin-induced oxidative stress stimulates renal Fas ligand shedding

(2018) Hitesh Soni et al.   RENAL FAILURE

Loss of DEPTOR in renal tubules protects against cisplatin-induced acute kidney injury

(2018) Caixia Wang et al.   Cell Death & Disease

Histone deacetylase inhibitors protect against cisplatin-induced acute kidney injury by activating autophagy in proximal tubular cells

(2018) Jing Liu et al.   Cell Death & Disease

Sirtuin 7 Deficiency Ameliorates Cisplatin-induced Acute Kidney Injury Through Regulation of the Inflammatory Response

(2018) Yoshikazu Miyasato et al.   Scientific Reports

Pretreatment of Huaiqihuang extractum protects against cisplatin-induced nephrotoxicity

(2018) Yujiao Guo et al.   Scientific Reports

Mangiferin Ameliorates Cisplatin Induced Acute Kidney Injury by Upregulating Nrf-2 via the Activation of PI3K and Exhibits Synergistic Anticancer Activity With Cisplatin

(2018) Pritam Sadhukhan et al.   Frontiers in Pharmacology

Protective Effect of Nanoceria on Cisplatin-Induced Nephrotoxicity by Amelioration of Oxidative Stress and Pro-inflammatory Mechanisms

(2018) Mohd Aslam Saifi et al.   BIOLOGICAL TRACE ELEMENT RESEARCH

Kidney Protection Effect of Ginsenoside Re and Its Underlying Mechanisms on Cisplatin-Induced Kidney Injury

(2018) Zi Wang et al.   CELLULAR PHYSIOLOGY AND BIOCHEMISTRY

Tracking of Adipose-Derived Mesenchymal Stromal/Stem Cells in a Model of Cisplatin-Induced Acute Kidney Injury: Comparison of Bioluminescence Imaging versus qRT-PCR

(2018) Ralf Schubert et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Platycodon grandiflorum Saponins Ameliorate Cisplatin-Induced Acute Nephrotoxicity through the NF-κB-Mediated Inflammation and PI3K/Akt/Apoptosis Signaling Pathways

(2018) Weizhe Zhang et al.   Nutrients

Wnt4 is significantly upregulated during the early phases of cisplatin-induced acute kidney injury

(2018) Yi-Xin He et al.   Scientific Reports

Cisplatin-Induced Rodent Model of Kidney Injury: Characteristics and Challenges

(2018) Martina Perše et al.   Biomed Research International

Homocysteine causes vascular endothelial dysfunction by disrupting endoplasmic reticulum redox homeostasis

(2018) Xun Wu et al.   Redox Biology

Persistent increase in mitochondrial superoxide mediates cisplatin-induced chronic kidney disease

(2018) Kranti A. Mapuskar et al.   Redox Biology

Fragmentation of kidney epithelial cell primary cilia occurs by cisplatin and these cilia fragments are excreted into the urine

(2018) Min Jung Kong et al.   Redox Biology

Celastrol ameliorates cisplatin nephrotoxicity by inhibiting NF-κB and improving mitochondrial function

(2018) Xiaowen Yu et al.   EBioMedicine

γ-secretase inhibitor DAPT mitigates cisplatin-induced acute kidney injury by suppressing Notch1 signaling

(2018) Hitesh Soni et al.   JOURNAL OF CELLULAR AND MOLECULAR MEDICINE

Pseudoginsengenin DQ Exhibits Therapeutic Effects in Cisplatin-Induced Acute Kidney Injury via Sirt1/NF-κB and Caspase Signaling Pathway without Compromising Its Antitumor Activity in Mice

(2018) Zeng Qi et al.   MOLECULES

PINK1/Parkin-mediated mitophagy is activated in cisplatin nephrotoxicity to protect against kidney injury

(2018) Ying Wang et al.   Cell Death & Disease

Nephroprotective Effects of Benzyl Isothiocyanate and Resveratrol Against Cisplatin-Induced Oxidative Stress and Inflammation

(2018) Abdelazim Ibrahim et al.   Frontiers in Pharmacology

Magnesium attenuates cisplatin-induced nephrotoxicity by regulating the expression of renal transporters

(2017) Yoshitaka Saito et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Total Coumarins from Hydrangea paniculata Protect against Cisplatin-Induced Acute Kidney Damage in Mice by Suppressing Renal Inflammation and Apoptosis

(2017) Zhang Sen et al.   Evidence-based Complementary and Alternative Medicine

Mouse population-based evaluation of urinary protein and miRNA biomarker performance associated with cisplatin renal injury

(2017) Alison H Harrill et al.   EXPERIMENTAL BIOLOGY AND MEDICINE

Urinary protein biomarkers of kidney injury in patients receiving cisplatin chemotherapy

(2017) Blessy George et al.   EXPERIMENTAL BIOLOGY AND MEDICINE

MicroRNA-140-5p attenuated oxidative stress in Cisplatin induced acute kidney injury by activating Nrf2/ARE pathway through a Keap1-independent mechanism

(2017) Weitang Liao et al.   EXPERIMENTAL CELL RESEARCH

Dexmedetomidine protects against cisplatin-induced acute kidney injury in mice through regulating apoptosis and inflammation

(2017) H. Liang et al.   INFLAMMATION RESEARCH

Hyperhomocysteinemia Exacerbates Cisplatin-induced Acute Kidney Injury

(2017) Yanjun Long et al.   International Journal of Biological Sciences

Nephroprotective Effects of Saponins from Leaves of Panax quinquefolius against Cisplatin-Induced Acute Kidney Injury

(2017) Zhi-Na Ma et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Inhibiting glucosylceramide synthase exacerbates cisplatin-induced acute kidney injury

(2017) Tess V. Dupre et al.   JOURNAL OF LIPID RESEARCH

Cisplatin nephrotoxicity: a review of the literature

(2017) Sandhya Manohar et al.   JOURNAL OF NEPHROLOGY

Causes of Death after a Hospitalization with AKI

(2017) Samuel A. Silver et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

MicroRNA-709 Mediates Acute Tubular Injury through Effects on Mitochondrial Function

(2017) Yan Guo et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

IL233, A Novel IL-2 and IL-33 Hybrid Cytokine, Ameliorates Renal Injury

(2017) Marta E. Stremska et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

DNA methylation protects against cisplatin-induced kidney injury by regulating specific genes, including interferon regulatory factor 8

(2017) Chunyuan Guo et al.   KIDNEY INTERNATIONAL

Wogonin protects against cisplatin-induced acute kidney injury by targeting RIPK1-mediated necroptosis

(2017) Xiao-Ming Meng et al.   LABORATORY INVESTIGATION

NADPH oxidase 4 promotes cisplatin-induced acute kidney injury via ROS-mediated programmed cell death and inflammation

(2017) Xiao-Ming Meng et al.   LABORATORY INVESTIGATION

MATE-1 modulation by kinin B1 receptor enhances cisplatin efflux from renal cells

(2017) Gabriel R. Estrela et al.   MOLECULAR AND CELLULAR BIOCHEMISTRY

Mitochondrial Abnormality Facilitates Cyst Formation in Autosomal Dominant Polycystic Kidney Disease

(2017) Yu Ishimoto et al.   MOLECULAR AND CELLULAR BIOLOGY

Protective effects of apigenin and myricetin against cisplatin-induced nephrotoxicity in mice

(2017) Samar M. Hassan et al.   PHARMACEUTICAL BIOLOGY

Nephroprotective Effects of Anthocyanin from the Fruits of Panax ginseng (GFA) on Cisplatin-Induced Acute Kidney Injury in Mice

(2017) Zhen-Lan Qi et al.   PHYTOTHERAPY RESEARCH

Precocious obesity predisposes the development of more severe cisplatin-induced acute kidney injury in young adult mice

(2017) Rosemara S. Ribeiro et al.   PLoS One

Galangin ameliorates cisplatin-induced nephrotoxicity by attenuating oxidative stress, inflammation and cell death in mice through inhibition of ERK and NF-kappaB signaling

(2017) Yu-Ching Huang et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

Suppression of BMP-7 by histone deacetylase 2 promoted apoptosis of renal tubular epithelial cells in acute kidney injury

(2017) Taotao Ma et al.   Cell Death & Disease

Human mesenchymal stromal cells transplanted into mice stimulate renal tubular cells and enhance mitochondrial function

(2017) Luca Perico et al.   Nature Communications

Pre-incubation with hucMSC-exosomes prevents cisplatin-induced nephrotoxicity by activating autophagy

(2017) Bingying Wang et al.   Stem Cell Research & Therapy

Cisplatin Nephrotoxicity Might Have a Sex Difference. An analysis Based on Women's Sex Hormone Changes.

(2017) Wei-Yu Chen et al.   Journal of Cancer

Activation of Sirtuin 3 by Silybin Attenuates Mitochondrial Dysfunction in Cisplatin-induced Acute Kidney Injury

(2017) Yin Li et al.   Frontiers in Pharmacology

Blocking junctional adhesion molecule C promotes the recovery of cisplatin-induced acute kidney injury

(2017) Sun Chul Kim et al.   KOREAN JOURNAL OF INTERNAL MEDICINE

Glutamyl aminopeptidase in microvesicular and exosomal fractions of urine is related with renal dysfunction in cisplatin-treated rats

(2017) Andrés Quesada et al.   PLoS One

Activation of endoplasmic reticulum stress response by enhanced polyamine catabolism is important in the mediation of cisplatin-induced acute kidney injury

(2017) Kamyar Zahedi et al.   PLoS One

Incidence of Severe Nephrotoxicity With Cisplatin Based on Renal Function Eligibility Criteria

(2016) Arati Dahal et al.   AMERICAN JOURNAL OF CLINICAL ONCOLOGY-CANCER CLINICAL TRIALS

Activation of apoptosis signalling pathways by reactive oxygen species

(2016) Maureen Redza-Dutordoir et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

Short-term preconditioning enhances the therapeutic potential of adipose-derived stromal/stem cell-conditioned medium in cisplatin-induced acute kidney injury

(2016) Jürgen M. Overath et al.   EXPERIMENTAL CELL RESEARCH

Carvacrol attenuates acute kidney injury induced by cisplatin through suppression of ERK and PI3K/Akt activation

(2016) Iva Potočnjak et al.   FOOD AND CHEMICAL TOXICOLOGY

The protective effects of Ribes diacanthum Pall on cisplatin-induced nephrotoxicity in mice

(2016) Akhtolkhyn Tilyek et al.   JOURNAL OF ETHNOPHARMACOLOGY

Competing Actions of Type 1 Angiotensin II Receptors Expressed on T Lymphocytes and Kidney Epithelium during Cisplatin-Induced AKI

(2016) J. Zhang et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Beneficial Effects ofMyo-Inositol Oxygenase Deficiency in Cisplatin-Induced AKI

(2016) Rajesh K. Dutta et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Protein Kinase C δ Suppresses Autophagy to Induce Kidney Cell Apoptosis in Cisplatin Nephrotoxicity

(2016) Dongshan Zhang et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Interstitial renal fibrosis due to multiple cisplatin treatments is ameliorated by semicarbazide-sensitive amine oxidase inhibition

(2016) Daisuke Katagiri et al.   KIDNEY INTERNATIONAL

Autophagy in acute kidney injury

(2016) Gur P. Kaushal et al.   KIDNEY INTERNATIONAL

Nephrotoxicity of anticancer treatment

(2016) Jolanta Małyszko et al.   NEPHROLOGY DIALYSIS TRANSPLANTATION

β-Lapachone enhances Mre11-Rad50-Nbs1 complex expression in cisplatin-induced nephrotoxicity

(2016) Tae-Won Kim et al.   Pharmacological Reports

Amelioration of cisplatin-induced acute kidney injury by recombinant neutrophil gelatinase-associated lipocalin

(2016) Qing Ma et al.   RENAL FAILURE

DNA damage response in nephrotoxic and ischemic kidney injury

(2016) Mingjuan Yan et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

Deletion of NAD(P)H:quinone oxidoreductase 1 represses Mre11-Rad50-Nbs1 complex protein expression in cisplatin-induced nephrotoxicity

(2016) Young-Jung Kim et al.   TOXICOLOGY LETTERS

NF-κB transcriptional inhibition ameliorates cisplatin-induced acute kidney injury (AKI)

(2016) Abdullah Ozkok et al.   TOXICOLOGY LETTERS

A potential adjuvant chemotherapeutics, 18β-glycyrrhetinic acid, inhibits renal tubular epithelial cells apoptosis via enhancing BMP-7 epigenetically through targeting HDAC2

(2016) Taotao Ma et al.   Scientific Reports

Improved Protective Effect of Umbilical Cord Stem Cell Transplantation on Cisplatin-Induced Kidney Injury in Mice Pretreated with Antithymocyte Globulin

(2016) Željka Večerić-Haler et al.   Stem Cells International

Metformin Protects Against Cisplatin-Induced Tubular Cell Apoptosis and Acute Kidney Injury via AMPKα-regulated Autophagy Induction

(2016) Jianzhong Li et al.   Scientific Reports

Organic Anion Transporter 5 (Oat5) Urinary Excretion Is a Specific Biomarker of Kidney Injury: Evaluation of Urinary Excretion of Exosomal Oat5 after N-Acetylcysteine Prevention of Cisplatin Induced Nephrotoxicity

(2015) Romina Paula Bulacio et al.   CHEMICAL RESEARCH IN TOXICOLOGY

Mitochondria-targeted antioxidants

(2015) Anne O. Oyewole et al.   FASEB JOURNAL

Renoprotective mechanisms of morin in cisplatin-induced kidney injury

(2015) Zhengkai Wei et al.   INTERNATIONAL IMMUNOPHARMACOLOGY

KIM-1–mediated phagocytosis reduces acute injury to the kidney

(2015) Li Yang et al.   JOURNAL OF CLINICAL INVESTIGATION

Sirtuin 3–dependent mitochondrial dynamic improvements protect against acute kidney injury

(2015) Marina Morigi et al.   JOURNAL OF CLINICAL INVESTIGATION

CD4 T cell knockout does not protect against kidney injury and worsens cancer

(2015) Kameswaran Ravichandran et al.   JOURNAL OF MOLECULAR MEDICINE-JMM

Three-Dimensional Morphology by Multiphoton Microscopy with Clearing in a Model of Cisplatin-Induced CKD

(2015) R. Torres et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

A Role for Tubular Necroptosis in Cisplatin-Induced AKI

(2015) Y. Xu et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Phospholipase A2 inhibits cisplatin-induced acute kidney injury by modulating regulatory T cells by the CD206 mannose receptor

(2015) Hyunseong Kim et al.   KIDNEY INTERNATIONAL

Oral administration of oleuropein attenuates cisplatin-induced acute renal injury in mice through inhibition of ERK signaling

(2015) Iva Potočnjak et al.   MOLECULAR NUTRITION & FOOD RESEARCH

MG53-mediated cell membrane repair protects against acute kidney injury

(2015) Pu Duann et al.   Science Translational Medicine

Role of transporters in the distribution of platinum-based drugs

(2015) Saliha Harrach et al.   Frontiers in Pharmacology

Renal Klotho expression in patients with acute kidney injury is associated with the severity of the injury

(2015) Min Young Seo et al.   KOREAN JOURNAL OF INTERNAL MEDICINE

Baicalein, a Bioflavonoid, Prevents Cisplatin-Induced Acute Kidney Injury by Up-Regulating Antioxidant Defenses and Down-Regulating the MAPKs and NF-κB Pathways

(2015) Bidya Dhar Sahu et al.   PLoS One

Transgenic Expression of the Human MRP2 Transporter Reduces Cisplatin Accumulation and Nephrotoxicity in Mrp2-Null Mice

(2014) Xia Wen et al.   AMERICAN JOURNAL OF PATHOLOGY

Age-related differences in kidney injury biomarkers induced by cisplatin

(2014) Yu Jin Shin et al.   ENVIRONMENTAL TOXICOLOGY AND PHARMACOLOGY

Cisplatin in cancer therapy: Molecular mechanisms of action

(2014) Shaloam Dasari et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Specific Macrophage Subtypes Influence the Progression of Rhabdomyolysis-Induced Kidney Injury

(2014) J. Belliere et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

G31P, CXCR1/2 inhibitor, with cisplatin inhibits the growth of mice hepatocellular carcinoma and mitigates high-dose cisplatin-induced nephrotoxicity

(2014) LINGYUN LI et al.   ONCOLOGY REPORTS

Long-Term Aerobic Exercise Protects against Cisplatin-Induced Nephrotoxicity by Modulating the Expression of IL-6 and HO-1

(2014) Mariana Yasue Saito Miyagi et al.   PLoS One

MicroRNA-155 Deficient Mice Experience Heightened Kidney Toxicity When Dosed with Cisplatin

(2014) Kathryn L. Pellegrini et al.   TOXICOLOGICAL SCIENCES

P2X7 receptor blockade protects against cisplatin-induced nephrotoxicity in mice by decreasing the activities of inflammasome components, oxidative stress and caspase-3

(2014) Yuanyuan Zhang et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

The pseudoginsenoside F11 ameliorates cisplatin-induced nephrotoxicity without compromising its anti-tumor activity in vivo

(2014) Hongbo Wang et al.   Scientific Reports

Pathophysiology of Cisplatin-Induced Acute Kidney Injury

(2014) Abdullah Ozkok et al.   Biomed Research International

Fibroblast Growth Factor 23 and Klotho: Physiology and Pathophysiology of an Endocrine Network of Mineral Metabolism

(2013) Ming Chang Hu et al.   Annual Review of Physiology

Urinary chemokine (C-C motif) ligand 2 (monocyte chemotactic protein-1) as a tubular injury marker for early detection of cisplatin-induced nephrotoxicity

(2013) Kumiko Nishihara et al.   BIOCHEMICAL PHARMACOLOGY

Regulatory T Cells in AKI

(2013) G. R. Kinsey et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Exosomes released by human umbilical cord mesenchymal stem cells protect against cisplatin-induced renal oxidative stress and apoptosis in vivo and in vitro

(2013) Ying Zhou et al.   Stem Cell Research & Therapy

Autophagy Guards Against Cisplatin-Induced Acute Kidney Injury

(2012) Atsushi Takahashi et al.   AMERICAN JOURNAL OF PATHOLOGY

Methods for Detection of Mitochondrial and Cellular Reactive Oxygen Species

(2012) Sergey I. Dikalov et al.   ANTIOXIDANTS & REDOX SIGNALING

Reactive oxygen species (ROS) homeostasis and redox regulation in cellular signaling

(2012) Paul D. Ray et al.   CELLULAR SIGNALLING

Tumor Necrosis Factor-α Signaling in Macrophages

(2012) Narayanan Parameswaran et al.   CRITICAL REVIEWS IN EUKARYOTIC GENE EXPRESSION

Cisplatin-loaded core cross-linked micelles: comparative pharmacokinetics, antitumor activity, and toxicity in mice

(2012) Hardeep Oberoi et al.   International Journal of Nanomedicine

Erythropoietin protects against cisplatin-induced nephrotoxicity by attenuating endoplasmic reticulum stress-induced apoptosis

(2012) Deyang Kong et al.   JOURNAL OF NEPHROLOGY

Yes, AKI Truly Leads to CKD

(2012) C.-y. Hsu   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Mononuclear phagocyte depletion strategies in models of acute kidney disease: what are they trying to tell us?

(2012) Matthew D. Griffin   KIDNEY INTERNATIONAL

Autophagy in proximal tubules protects against acute kidney injury

(2012) Man Jiang et al.   KIDNEY INTERNATIONAL

MFG-E8 Regulates the Immunogenic Potential of Dendritic Cells Primed with Necrotic Cell-Mediated Inflammatory Signals

(2012) Muhammad Baghdadi et al.   PLoS One

Mitochondrial Fission, Fusion, and Stress

(2012) R. J. Youle et al.   SCIENCE

Effect of erythropoietin therapy on the progression of cisplatin induced renal injury in rats

(2011) Hoda E. Mohamed et al.   EXPERIMENTAL AND TOXICOLOGIC PATHOLOGY

Phosphate and Klotho

(2011) Makoto Kuro-o   KIDNEY INTERNATIONAL

Increased risk of death and de novo chronic kidney disease following reversible acute kidney injury

(2011) Ion D. Bucaloiu et al.   KIDNEY INTERNATIONAL

Klotho suppresses RIG-I-mediated senescence-associated inflammation

(2011) Feng Liu et al.   NATURE CELL BIOLOGY

The junctional adhesion molecule JAM-C regulates polarized transendothelial migration of neutrophils in vivo

(2011) Abigail Woodfin et al.   NATURE IMMUNOLOGY

Necrotic Concentrations of Cisplatin Activate the Apoptotic Machinery but Inhibit Effector Caspases and Interfere with the Execution of Apoptosis

(2011) Sandra M. Sancho-Martínez et al.   TOXICOLOGICAL SCIENCES

Protecting Cisplatin-Induced Nephrotoxicity with Cimetidine Does Not Affect Antitumor Activity

(2010) Hiromu Katsuda et al.   BIOLOGICAL & PHARMACEUTICAL BULLETIN

Serum Creatinine and Glomerular Filtration Rate: Perception and Reality

(2010) R. N. Dalton   CLINICAL CHEMISTRY

Modeling metastasis in the mouse

(2010) Paula D Bos et al.   CURRENT OPINION IN PHARMACOLOGY

Dietary and genetic evidence for phosphate toxicity accelerating mammalian aging

(2010) Mutsuko Ohnishi et al.   FASEB JOURNAL

Klotho: a novel phosphaturic substance acting as an autocrine enzyme in the renal proximal tubule

(2010) Ming Chang Hu et al.   FASEB JOURNAL

Kidney-specific Overexpression of Sirt1 Protects against Acute Kidney Injury by Retaining Peroxisome Function

(2010) Kazuhiro Hasegawa et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Mechanisms of Cisplatin Nephrotoxicity

(2010) Ronald P. Miller et al.   Toxins

Guidelines for the use and interpretation of assays for monitoring cell death in higher eukaryotes

(2009) L Galluzzi et al.   CELL DEATH AND DIFFERENTIATION

Neutrophil Gelatinase-Associated Lipocalin (NGAL) and Progression of Chronic Kidney Disease

(2009) D. Bolignano et al.   Clinical Journal of the American Society of Nephrology

Renal Dendritic Cells Ameliorate Nephrotoxic Acute Kidney Injury

(2009) R. K. Tadagavadi et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Neutrophils in acute kidney injury: not neutral any more

(2009) Subhashini Bolisetty et al.   KIDNEY INTERNATIONAL

The Inflammatory Response to Cell Death

(2008) Kenneth L. Rock et al.   Annual Review of Pathology-Mechanisms of Disease

The mitochondrial p53 pathway

(2008) Angelina V. Vaseva et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOENERGETICS

Autophagy in the Pathogenesis of Disease

(2008) Beth Levine et al.   CELL

Epidemiology of Acute Kidney Injury

(2008) J. Cerda et al.   Clinical Journal of the American Society of Nephrology

Urinary exosomal transcription factors, a new class of biomarkers for renal disease

(2008) Hua Zhou et al.   KIDNEY INTERNATIONAL