C-peptide prevents NF-κB from recruiting p300 and binding to the inos promoter in diabetic nephropathy

Natural antioxidants in the treatment and prevention of diabetic nephropathy; a potential approach that warrants clinical trials

(2017) Noori Al-Waili et al.   REDOX REPORT

Long-Acting C-Peptide and Neuropathy in Type 1 Diabetes: A 12-Month Clinical Trial

(2016) John Wahren et al.   DIABETES CARE

C-peptide protects against hyperglycemic memory and vascular endothelial cell apoptosis

(2016) Mahendra Prasad Bhatt et al.   JOURNAL OF ENDOCRINOLOGY

C-peptide antioxidant adaptive pathways in β cells and diabetes

(2016) P. Luppi et al.   JOURNAL OF INTERNAL MEDICINE

C-peptide and diabetic kidney disease

(2016) N. J. Brunskill   JOURNAL OF INTERNAL MEDICINE

Up-Regulation of Human Inducible Nitric Oxide Synthase by p300 Transcriptional Complex

(2016) Zhong Guo et al.   PLoS One

C-peptide ameliorates renal injury in type 2 diabetic rats through protein kinase A-mediated inhibition of fibronectin synthesis

(2015) Shiqing Xu et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Novel curcumin analog C66 prevents diabetic nephropathy via JNK pathway with the involvement of p300/CBP-mediated histone acetylation

(2015) Yangwei Wang et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

C-peptide: New findings and therapeutic possibilities

(2015) John Wahren et al.   DIABETES RESEARCH AND CLINICAL PRACTICE

C-peptide modifies leptin and visfatin secretion in human adipose tissue

(2015) Sara Garcia-Serrano et al.   Obesity

C-peptide as a Therapy for Kidney Disease: A Systematic Review and Meta-Analysis

(2015) James A. Shaw et al.   PLoS One

A subdivided molecular architecture with separate features and stepwise emergence among proinsulin C-peptides

(2014) Michael Landreh et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Role of Transcription Factor Acetylation in Diabetic Kidney Disease

(2014) R. Liu et al.   DIABETES

Evaluating the Role of Epigenetic Histone Modifications in the Metabolic Memory of Type 1 Diabetes

(2014) Feng Miao et al.   DIABETES

MicroRNA-29a Promotion of Nephrin Acetylation Ameliorates Hyperglycemia-Induced Podocyte Dysfunction

(2014) C.-L. Lin et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Diabetic nephropathy—emerging epigenetic mechanisms

(2014) Mitsuo Kato et al.   Nature Reviews Nephrology

Prevention of VEGF-mediated microvascular permeability by C-peptide in diabetic mice

(2013) Y.-C. Lim et al.   CARDIOVASCULAR RESEARCH

Biochemical Basis of the Antidiabetic Activity of Oleanolic Acid and Related Pentacyclic Triterpenes

(2013) J. M. Castellano et al.   DIABETES

Up-down Regulation of HO-1 and iNOS Gene Expressions by Ethyl Pyruvate via Recruiting p300 to Nrf2 and Depriving It from p65

(2013) Seung-Woo Kim et al.   FREE RADICAL BIOLOGY AND MEDICINE

Losartan reverses permissive epigenetic changes in renal glomeruli of diabetic db/db mice

(2013) Marpadga A. Reddy et al.   KIDNEY INTERNATIONAL

Dynamic localization and functional implications of C-peptide might for suppression of iNOS in high glucose-stimulated rat mesangial cells

(2013) Yanning Li et al.   MOLECULAR AND CELLULAR ENDOCRINOLOGY

Protein nitration promotes inducible nitric oxide synthase transcription mediated by NF-κB in high glucose-stimulated human lens epithelial cells

(2013) Yanning Li et al.   MOLECULAR AND CELLULAR ENDOCRINOLOGY

Diabetic nephropathy: diagnosis and treatment

(2013) Daniel Fineberg et al.   Nature Reviews Endocrinology

Inhibition of lipopolysaccharide-induced inducible nitric oxide synthase expression by endoplasmic reticulum stress

(2012) Hui-Ju Ho et al.   CELLULAR SIGNALLING

The Clinical Potential of C-Peptide Replacement in Type 1 Diabetes

(2012) J. Wahren et al.   DIABETES

C-Peptide Prevents Hyperglycemia-Induced Endothelial Apoptosis Through Inhibition of Reactive Oxygen Species–Mediated Transglutaminase 2 Activation

(2012) Mahendra Prasad Bhatt et al.   DIABETES

Prediabetic Nephropathy as an Early Consequence of the High-Calorie/High-Fat Diet: Relation to Oxidative Stress

(2012) Hanna Shevalye et al.   ENDOCRINOLOGY

Proinsulin C-peptide activates α-enolase: implications for C-peptide–cell membrane interaction

(2012) Tatsuya Ishii et al.   JOURNAL OF BIOCHEMISTRY

Oxidative stress and myocardial injury in the diabetic heart

(2012) David M Ansley et al.   JOURNAL OF PATHOLOGY

Beneficial effects of C-peptide on renal morphology in diabetic rats

(2010) W. Sun et al.   ACTA BIOCHIMICA ET BIOPHYSICA SINICA

C-Peptide as a Therapeutic Tool in Diabetic Nephropathy

(2010) Claire E. Hills et al.   AMERICAN JOURNAL OF NEPHROLOGY

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(2010) Yanning Li et al.   MOLECULAR MEDICINE

C-peptide is internalised in human endothelial and vascular smooth muscle cells via early endosomes

(2009) P. Luppi et al.   DIABETOLOGIA

Therapeutic interventions and oxidative stress in diabetes

(2009) Shilpa Rahangdale   Frontiers in Bioscience-Landmark

Proinsulin C-peptide Regulates Ribosomal RNA Expression

(2009) Emma Lindahl et al.   JOURNAL OF BIOLOGICAL CHEMISTRY