Supplementation of Saponins from Leaves of Panax quinquefolius Mitigates Cisplatin-Evoked Cardiotoxicity via Inhibiting Oxidative Stress-Associated Inflammation and Apoptosis in Mice

Maltol Mitigates Thioacetamide-induced Liver Fibrosis through TGF-β1-mediated Activation of PI3K/Akt Signaling Pathway

(2019) Xiao-jie Mi et al.   JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

Ginsenoside Rb3 provides protective effects against cisplatin‐induced nephrotoxicity via regulation of AMPK‐/mTOR‐mediated autophagy and inhibition of apoptosis in vitro and in vivo

(2019) Jing‐jing Xing et al.   CELL PROLIFERATION

Arginyl-fructosyl-glucose, a Major Maillard Reaction Product of Red Ginseng, Attenuates Cisplatin-Induced Acute Kidney Injury by Regulating Nuclear Factor κB and Phosphatidylinositol 3-Kinase/Protein Kinase B Signaling Pathways

(2019) Rong-yan Li et al.   JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

Leonurine protects cardiac function following acute myocardial infarction through anti‑apoptosis by the PI3K/AKT/GSK3β signaling pathway

(2018) Lin Xu et al.   Molecular Medicine Reports

Panax quinquefolius saponins combined with dual antiplatelet drug therapy alleviate gastric mucosal injury and thrombogenesis through the COX/PG pathway in a rat model of acute myocardial infarction

(2018) Na Kou et al.   PLoS One

The effect of rutin on cisplatin-induced oxidative cardiac damage in rats

(2018) Ismail Topal   Anatolian Journal of Cardiology

Protective effects of curcumin and beta-carotene on cisplatin-induced cardiotoxicity: An experimental rat model

(2018) Anzel Bahadır   Anatolian Journal of Cardiology

The protective effects of maltol on cisplatin-induced nephrotoxicity through the AMPK-mediated PI3K/Akt and p53 signaling pathways

(2018) Xiao-jie Mi et al.   Scientific Reports

Nephroprotective Effects of Saponins from Leaves of Panax quinquefolius against Cisplatin-Induced Acute Kidney Injury

(2017) Zhi-Na Ma et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Saponins (Ginsenosides) from the Leaves of Panax quinquefolius Ameliorated Acetaminophen-Induced Hepatotoxicity in Mice

(2017) Xing-Yue Xu et al.   JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

Cisplatin triggers cancer stem cell enrichment in platinum-resistant cells through NF-κB-TNFα-PIK3CA loop

(2017) Bhushan Thakur et al.   JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH

Protective effect of rutin supplementation against cisplatin-induced Nephrotoxicity in rats

(2017) Ali R. Alhoshani et al.   BMC Nephrology

Renoprotective effects of emodin against diabetic nephropathy in rat models are mediated via PI3K/Akt/GSK‑3β and Bax/caspase‑3 signaling pathways

(2017) Danqing Jing et al.   Experimental and Therapeutic Medicine

S‐Allylmercaptocysteine Attenuates Cisplatin‐Induced Nephrotoxicity through Suppression of Apoptosis, Oxidative Stress, and Inflammation

(2017) Xiaosong Zhu et al.   Nutrients

Drp1-dependent mitophagy protects against cisplatin-induced apoptosis of renal tubular epithelial cells by improving mitochondrial function

(2017) Chuanyan Zhao et al.   Oncotarget

Ginsenoside Rk1 ameliorates paracetamol-induced hepatotoxicity in mice through inhibition of inflammation, oxidative stress, nitrative stress and apoptosis

(2017) Jun-Nan Hu et al.   Journal of Ginseng Research

Brain-derived neurotrophic factor attenuates doxorubicin-induced cardiac dysfunction through activating Akt signalling in rats

(2016) Pengzhou Hang et al.   JOURNAL OF CELLULAR AND MOLECULAR MEDICINE

Insights into the Role and Interdependence of Oxidative Stress and Inflammation in Liver Diseases

(2016) Sha Li et al.   Oxidative Medicine and Cellular Longevity

An integrative view of cisplatin-induced renal and cardiac toxicities: Molecular mechanisms, current treatment challenges and potential protective measures

(2016) George J. Dugbartey et al.   TOXICOLOGY

Drug-induced mitochondrial dysfunction and cardiotoxicity

(2015) Zoltán V Varga et al.   AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY

PAK4 confers the malignance of cervical cancers and contributes to the cisplatin-resistance in cervical cancer cells via PI3K/AKT pathway

(2015) Xiang-Rong Shu et al.   Diagnostic Pathology

An integrated view of cisplatin-induced nephrotoxicity and ototoxicity

(2015) Takatoshi Karasawa et al.   TOXICOLOGY LETTERS

Mechanism of Cisplatin-Induced Cytotoxicity Is Correlated to Impaired Metabolism Due to Mitochondrial ROS Generation

(2015) Yong-Min Choi et al.   PLoS One

Cisplatin in cancer therapy: Molecular mechanisms of action

(2014) Shaloam Dasari et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Obesity Activates a Program of Lysosomal-Dependent Lipid Metabolism in Adipose Tissue Macrophages Independently of Classic Activation

(2013) Xiaoyuan Xu et al.   Cell Metabolism

Cisplatin Induces a Mitochondrial-ROS Response That Contributes to Cytotoxicity Depending on Mitochondrial Redox Status and Bioenergetic Functions

(2013) Rossella Marullo et al.   PLoS One

Protein tyrosine phosphatase 1B modulates GSK3β/Nrf2 and IGFIR signaling pathways in acetaminophen-induced hepatotoxicity

(2013) M A Mobasher et al.   Cell Death & Disease

Role of CFTR in oxidative stress and suicidal death of renal cells during cisplatin-induced nephrotoxicity

(2013) I Rubera et al.   Cell Death & Disease

Carbamylated erythropoietin attenuates cardiomyopathy via PI3K/Akt activation in rats with diabetic cardiomyopathy

(2013) HONGYING HE et al.   Experimental and Therapeutic Medicine

Poly(ADP-ribose) polymerase-1 is a key mediator of cisplatin-induced kidney inflammation and injury

(2011) Partha Mukhopadhyay et al.   FREE RADICAL BIOLOGY AND MEDICINE

Suppression of GSK-3  activation by M-cadherin protects myoblasts against mitochondria-associated apoptosis during myogenic differentiation

(2011) Y. Wang et al.   JOURNAL OF CELL SCIENCE